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Can a Nasal Decongestant Test Predict Treatment Outcomes in Seasonal Allergic Rhinitis?

2014-07-24 14:18:48 | BioPortfolio

Summary

We hypothesize that those patients with purely seasonal allergic rhinitis will decongest better than those subjects with another cause contributing to their symptoms. These latter patients will not improve as well on an intranasal steroid as those who decongest well, potentially explaining the 60% response rate in prior studies.

Study Design

Allocation: Randomized, Control: Placebo Control, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator)

Conditions

Seasonal Allergic Rhinitis

Intervention

mometasone furoate nasal spray, placebo

Location

University of Chicago
Chicago
Illinois
United States
60637

Status

Active, not recruiting

Source

University of Chicago

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:18:48-0400

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Medical and Biotech [MESH] Definitions

A pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for skin disorders.

Application of allergens to the nasal mucosa. Interpretation includes observation of nasal symptoms, rhinoscopy, and rhinomanometry. Nasal provocation tests are used in the diagnosis of nasal hypersensitivity, including RHINITIS, ALLERGIC, SEASONAL.

Allergic rhinitis that occurs at the same time every year. It is characterized by acute CONJUNCTIVITIS with lacrimation and ITCHING, and regarded as an allergic condition triggered by specific ALLERGENS.

A pharmaceutical preparation of mometasone furoate and formoterol fumarate that is used as an inhaled dosage form for the treatment of ASTHMA.

A form of non-allergic rhinitis that is characterized by nasal congestion and posterior pharyngeal drainage.

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