Markers of Defective Membrane Remodelling in Scott-like Syndromes

2014-08-27 03:32:51 | BioPortfolio


Purpose: Identification of the gene(s) involved in plasma membrane remodelling. Identification of the circulating markers affected by the defective membrane remodelling in a collection of families with unexplained provoked hemorrhages and evaluation of their prognosis value in the assessment of the hemostatic cellular response.Hypothesis: Scott syndrome is rare a familial disorder characterized by provoked haemorrages in homozygous-type patients due to isolated membrane remodelling deficiency. Membrane remodelling is necessary for cellular hemostatic responses.

Study Design

Observational Model: Family-Based, Time Perspective: Prospective


Unexplained Isolated Provoked Hemorrhages


Blood withdrawal


Hôpital Antoine Béclère, Service d'Hématologie Biologique




University Hospital, Strasbourg, France

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:32:51-0400

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