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Markers of Defective Membrane Remodelling in Scott-like Syndromes

2014-08-27 03:32:51 | BioPortfolio

Summary

Purpose: Identification of the gene(s) involved in plasma membrane remodelling. Identification of the circulating markers affected by the defective membrane remodelling in a collection of families with unexplained provoked hemorrhages and evaluation of their prognosis value in the assessment of the hemostatic cellular response.Hypothesis: Scott syndrome is rare a familial disorder characterized by provoked haemorrages in homozygous-type patients due to isolated membrane remodelling deficiency. Membrane remodelling is necessary for cellular hemostatic responses.

Study Design

Observational Model: Family-Based, Time Perspective: Prospective

Conditions

Unexplained Isolated Provoked Hemorrhages

Intervention

Blood withdrawal

Location

Hôpital Antoine Béclère, Service d'Hématologie Biologique
Clamart
France
92140

Status

Recruiting

Source

University Hospital, Strasbourg, France

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:32:51-0400

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