Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic Women

2014-08-27 03:32:56 | BioPortfolio


This study will enroll 20 adult Hispanic women. Participants will apply 4% hydroquinone cream twice daily to affected areas on the face for 14 weeks and half the face will be peeled with 20-30% salicylic acid every two weeks for a total of 4 peels. The first two peels will be 20% salicylic acid and the second two peels will be with 30% salicylic acid. The purpose of the study will be to evaluate the safety and efficacy of salicylic acid combined with 4% hydroquinone versus 4% hydroquinone alone.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment




20-30% Salicylic Acid peels to the right side of the face, 20-30% Salicylic Acid peels to the left side of the face


UT Southwestern Medical Center at Dallas - Dermatology Clinical Trials
United States




University of Texas Southwestern Medical Center

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:32:56-0400

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Medical and Biotech [MESH] Definitions

Derivatives and salts of SALICYLIC ACID.

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