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Albumin Use in Burn Patients

2014-08-27 03:33:10 | BioPortfolio

Summary

This is a study of why and how physicians use albumin during the first 72 hours after a burn injury.

Description

While albumin has been a part of burn resuscitation for many years, its use remains varied and controversial. The purpose of this study is to describe the current practices of albumin administration during the first 72 hours after a burn injury. Participating sites will collect data on patients with at least a 20% Total Body Surface Area (TBSA) burn. Information will be recorded on type and extent of burn injury, basic demographic data, co-morbidities, outcomes and, for the first 72 hours post injury, if albumin was used and why, amount of resuscitation fluids and urine output, and use of vasopressors and diuretics.

Each participating site will retrospectively review 20 charts of consecutive admissions with at least a 20% TBSA burn. In addition, each site will collect data prospectively on 20 more patients with 20% TBSA burns. Prospective data is requested in order to capture as close as possible to "real time" the reasons physicians choose to give albumin. No Protected Health Information (PHI) will be recorded.

Data will be analyzed for patterns of albumin use and reasons for albumin administration.

Study Design

Time Perspective: Prospective

Conditions

Burns

Location

Arizona Burn Center, Maricopa Medical Center
Phoenix
Arizona
United States
85008

Status

Completed

Source

University of North Carolina, Chapel Hill

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:33:10-0400

Clinical Trials [83 Associated Clinical Trials listed on BioPortfolio]

Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults

This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in adult patients with partial deep dermal and full thickness bur...

The Effects of Hyperbaric Oxygen Therapy (HBOT) on Acute Thermal Burns

The blinded RCTstudy aims to: - Determine the effects of HBOT on burns conversion for patients who have fresh thermal burns injury using the LDI. - Objectively determine...

Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Children

This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in children with partial deep dermal and full thickness burns.

The Role of Amniotic Membrane Transplantation in Ocular Chemical Burns

This is a randomized clinical trial study to identify the role of AMT (amniotic membrane transplantation) in treating epithelial defect, symblepharon prevention preventing corneal vascular...

Efficacy and Safety Study of Soluble Beta-1,3/1,6-Glucan in Thermal Burns

The purpose of this study is to determine whether soluble beta-1,3/1,6-glucan is an effective and safe treatment of thermal burns and non-injured skin where skin grafts are harvested. ...

PubMed Articles [170 Associated PubMed Articles listed on BioPortfolio]

The Southwest UK Burns Network (SWUK) experience of electronic cigarette explosions and review of literature.

Since the introduction of e-cigarettes to the UK market in 2007 their popularity amongst young adults has significantly increased. These lithium-ion powered devices remain unregulated by the Standards...

Two new risk factors for heterotopic ossification development after severe burns.

Life after severe burns is conditioned by the remaining sequelae. The pathophysiology and risk factors of Heterotopic Ossification (HO) after burns are still poorly understood. The aim of this study w...

Differing energy densities with laser 670nm InGaP controls inflammation and collagen reorganization in burns.

This study compared different energy densities of laser on second degrees burns in rats aiming to determine the most effective dosimetry in stimulation of the healing process.

A difference in outcomes for diabetic patients with burns to their feet.

Consideration of the use of commercial flights to transfer patients with burns.

Medical and Biotech [MESH] Definitions

Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Burns caused by contact with or exposure to CAUSTICS or strong ACIDS.

Burns of the respiratory tract caused by heat or inhaled chemicals.

Burns produced by contact with electric current or from a sudden discharge of electricity.

Injuries caused by electric currents. The concept excludes electric burns (BURNS, ELECTRIC), but includes accidental electrocution and electric shock.

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