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Intraoperative M-Entropy Measurements

2014-07-24 14:19:09 | BioPortfolio

Summary

The purpose of this study is to learn more about an Entropy monitor that your anesthesiologist will be using.

Description

Depth of anesthesia monitors are increasingly used in clinical anesthesia practice. Bispectral Index (BIS) and M-Entropy are examples to these devices, both of which are available at our institution. Both BIS and M-Entropy use a unilateral, single channel of EEG to derive a number indicating the anesthetic depth. These devices have similar disposable skin probes that can be applied on either side of the forehead. Since the depth of anesthesia for an individual is the same over the whole brain cortex at a given point in time, BIS numbers obtained over the left and right side of the forehead should agree. The same should be true for M-Entropy as well.

A recent study, however, showed that two separate BIS probes, applied over the left and right forehead of the same patient at the same time, can give significantly different numbers. This has not been studied for M-Entropy. BIS and M-Entropy use different mathematical algorithms that process the raw EEG signal to compute a numeric value. Therefore, it is possible that M-Entropy may show different results in a similar study setup.

Our aim is to investigate the same-patient reproducibility of M-Entropy by monitoring and recording Entropy variables over both the left and the right side of the forehead of patients under general anesthesia.

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Conditions

General Anesthesia

Intervention

Entropy monitor (Datex-Ohmeda S/5 EntropyTM Module)

Location

OU MEDICAL CENTER, Presbyterian Tower, OR
Oklahoma City
Oklahoma
United States
73104

Status

Completed

Source

University of Oklahoma

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:19:09-0400

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