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A Multi-Centre Clinical Study in Chronic Spinal Cord Injury Patients

2014-08-27 03:33:47 | BioPortfolio

Summary

To establish a solid foundation, e.g. network and a coordinating centre for testing new SCI therapies in forthcoming randomized controlled multi-centre clinical trials following international standards and guidelines

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Spinal Cord Injuries

Location

First Affiliated Hospital of Fujian Medical University
Fuzhou
Fujian
China

Status

Completed

Source

China Spinal Cord Injury Network

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:33:47-0400

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Prospective Survey of Body Mass Index in People With Spinal Cord Injury.

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Long-term Outcomes and Life Satisfaction of Adults With Pediatric-Onset Spinal Cord Injuries

The purpose of this study is to assess life satisfaction and long-term outcomes (i.e., medical and psychosocial) of adults who sustained spinal cord injuries (SCI) as children or adolesce...

PubMed Articles [3226 Associated PubMed Articles listed on BioPortfolio]

Long Term Follow-up Results of Spinal Concussion Cases: Definition of Late Injuries of the Spinal Cord.

This study aims to evaluate the long-term clinical and radiological findings of cases diagnosed with spinal concussion and to describe the spinal cord injuries that are detected in the later course.

Survival in 222 patients with severe cervical spinal cord injuries: an 8-year epidemiological survey in Western China.

To assess the survival and the predictors of mortality in patients with severe cervical spinal cord injuries DESIGN: Retrospective study PARTICIPANTS: From January 1, 2010 to May 31, 2018, 222 patient...

Investigation Of The Effect Of Alemtuzumab In An Experimental Spinal Cord Trauma Model In Rats.

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Medical and Biotech [MESH] Definitions

Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.

Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)

Longitudinal cavities in the spinal cord, most often in the cervical region, which may extend for multiple spinal levels. The cavities are lined by dense, gliogenous tissue and may be associated with SPINAL CORD NEOPLASMS; spinal cord traumatic injuries; and vascular malformations. Syringomyelia is marked clinically by pain and PARESTHESIA, muscular atrophy of the hands, and analgesia with thermoanesthesia of the hands and arms, but with the tactile sense preserved (sensory dissociation). Lower extremity spasticity and incontinence may also develop. (From Adams et al., Principles of Neurology, 6th ed, p1269)

Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.

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Spinal Cord Disorders
The spinal cord is a bundle of nerves that runs down the middle of the back which carry signals back and forth between the body and brain. It is protected by vertebrae, which are the bone disks that make up the spine. An accident that damages the verte...


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