New Treatment for Donor Sites

2014-08-27 03:33:49 | BioPortfolio


Primary research questions/Purpose of the Research.

1. Determine the short term (epidermal regeneration, reduction of pain, infections and length of stay) and long term (scarring, long term recovery, and cost of treatment) outcomes of Microbial Nanocellulose (NC) and fine mesh gauze impregnated with hyaluronan and thrombin (HT).

2. Determine if donor site treatment with NC and HT is as safe as the use of Scarlet Red ointment dressing.

b. Describe the importance of the knowledge that you expect to gain from the research.

To find a donor site dressing that has outcomes equal or better than that of scarlet red.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment




Application of donor site dressing [scarlet red, Microbial Nanocellulose (NC), or hyaluronan and thrombin (HT)], Blood sample, Biopsy


University of Texas Medical Branch
United States




The University of Texas, Galveston

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:33:49-0400

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Medical and Biotech [MESH] Definitions

Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.

The grafting of bone from a donor site to a recipient site.

The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.

The body location or part from which tissue is taken for TRANSPLANTATION.

A mismatch between donor and recipient blood. Antibodies present in the recipient's serum are directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)

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