Topics

New Treatment for Donor Sites

2014-08-27 03:33:49 | BioPortfolio

Summary

Primary research questions/Purpose of the Research.

1. Determine the short term (epidermal regeneration, reduction of pain, infections and length of stay) and long term (scarring, long term recovery, and cost of treatment) outcomes of Microbial Nanocellulose (NC) and fine mesh gauze impregnated with hyaluronan and thrombin (HT).

2. Determine if donor site treatment with NC and HT is as safe as the use of Scarlet Red ointment dressing.

b. Describe the importance of the knowledge that you expect to gain from the research.

To find a donor site dressing that has outcomes equal or better than that of scarlet red.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Burn

Intervention

Application of donor site dressing [scarlet red, Microbial Nanocellulose (NC), or hyaluronan and thrombin (HT)], Blood sample, Biopsy

Location

University of Texas Medical Branch
Galveston
Texas
United States
77551

Status

Recruiting

Source

The University of Texas, Galveston

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:33:49-0400

Clinical Trials [1743 Associated Clinical Trials listed on BioPortfolio]

Use of Banana Leaf Dressing on Donor Site Wounds

Prospective Randomized double-blind controlled trial comparing the healing rate, infection rate, pain score, ease of care and scar formation of Banana leaf dressing versus hydrocolloid dre...

Amniotic Membrane for Donor Site Healing

The purpose of this study is to compare the effectiveness of applying amniotic membrane dressings compared to gentamicin and xeroform dressings to donor sites for skin grafts. This study w...

Efficacy Study of a Bioelectric Dressing to Treat Skin Graft Donor Site Wounds

The purpose of this study is to determine whether the use of a bioelectric wound dressing is effective in the healing of skin graft donor site wounds.

Evaluation of ACell Hydrated Wound Dressing for Autogenous Skin Donor Sites

The purpose of this study is to see if treating a donor site wound with the ACell dressing is as good as or better than the dressings we currently treat harvested donor sites with. This wi...

Suprathel Versus Xeroform for the Management of Skin Graft Donor Sites

The investigators aim to study whether Suprathel, a synthetic temporary skin substitute developed by PolyMedics Innovations GmBH aids in the management of patient pain and wound healing wh...

PubMed Articles [13162 Associated PubMed Articles listed on BioPortfolio]

Effects of Dressing Materials on Donor Site Morbidity: A Comparative Study at a Tertiary Hospital in Kenya.

Skin graft donor wounds should heal with rapid epithelialization resulting in good aesthetic and minimal donor site morbidity. Several dressing materials are now available for the dressing of the dono...

Engineering nanocellulose hydrogels for biomedical applications.

Nanocellulose hydrogels are highly hydrated porous cellulosic soft materials with good mechanical properties. These cellulose-based gels can be produced from bacterial or plant cellulose nanofibrils, ...

Dermabond and Tegaderm, A Better Surgical Incision Dressing.

Surgical site infections (SSI) are a common source of morbidity with vascular surgery incisions, especially in the groin. Single institution case series' have widely varying, but high incidences of gr...

On-site fabrication of Bi-layered adhesive mesenchymal stromal cell-dressings for the treatment of heart failure.

Mesenchymal stromal/stem cell (MSC)-based therapy is a promising approach for the treatment of heart failure. However, current MSC-delivery methods result in poor donor cell engraftment, limiting the ...

Intracellular hyaluronan: Importance for cellular functions.

Hyaluronan-rich matrices are abundant in ECM and are involved in biological processes, such as cell growth and migration. Hyaluronan is synthesized by the hyaluronan synthase family of enzymes, HAS1, ...

Medical and Biotech [MESH] Definitions

Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.

The grafting of bone from a donor site to a recipient site.

The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.

The body location or part from which tissue is taken for TRANSPLANTATION.

A mismatch between donor and recipient blood. Antibodies present in the recipient's serum are directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)

More From BioPortfolio on "New Treatment for Donor Sites"

Quick Search

Relevant Topic

Pain
Pain is defined by the International Association for the Study of Pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage”. Some illnesses can be excruci...


Searches Linking to this Trial