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A Study to Investigate an Immunomodulatory Therapy in Adult Patients With Perennial Allergic Rhinoconjunctivits

2014-08-27 03:34:31 | BioPortfolio

Summary

The purpose of the study is to test the efficacy of the combination treatment AllQbG10 in patients with perennial allergic rhinoconjunctivits due to house dust mite allergy in a double-blind, placebo-controlled setting

Study Design

Allocation: Randomized, Control: Placebo Control, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Perennial Allergic Rhinoconjunctivitis

Intervention

CYT005-AllQbG10 (combination of house dust mite allergen extract with CYT003-QbG10), House dust mite allergen extract in combination with CYT003-QbG10-placebo, CYT003-AllQbG10 in combination with house dust mite allergen extract placebo, CYT003-QbG10-plac

Status

Completed

Source

Cytos Biotechnology AG

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:34:31-0400

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A Study to Investigate an Immunomodulatory Therapy in Adult Patients With Perennial Allergic Rhinoconjunctivitis

The purpose of the study is to test the efficacy of the combination treatment AllQbG10 in patients with perennial allergic rhinoconjunctivitis due to house dust mite allergy in a double-bl...

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PubMed Articles [2810 Associated PubMed Articles listed on BioPortfolio]

Underestimation of house dust mite-specific IgE with extract-based ImmunoCAPs compared to molecular ImmunoCAPs.

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Environmental exposure to endotoxin, Fel d I (cat) allergen and Der p I (house dust mite) allergen have been associated with asthma symptoms and have been measured in the environment using various sam...

Efficacy of house dust mite sublingual tablet in the treatment of allergic rhinoconjunctivitis: A randomized trial in a pediatric population.

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The emerging roles of the protease allergen Der p 1 in house dust mite-induced airway inflammation.

Allergen variability and house dust mite sensitivity in pre-school children with allergic complaints.

Yazıcı S, Güneş S, Kurtuluş-Çokboz M, Kemer Ö, Baranlı G, Aşık-Akman S, Can D. Allergen variability and house dust mite sensitivity in pre-school children with allergic complaints. Turk J Pe...

Medical and Biotech [MESH] Definitions

Species of European house dust mite, in the family PYROGLYPHIDAE. It is the most commonly found house dust mite.

Species of American house dust mite, in the family PYROGLYPHIDAE.

Antigens from the house dust mites (DERMATOPHAGOIDES), mainly D. farinae and D. pteronyssinus. They are proteins, found in mite feces or mite extracts, that can cause ASTHMA and other allergic diseases such as perennial rhinitis (RHINITIS, ALLERGIC, PERENNIAL) and atopic dermatitis (DERMATITIS, ATOPIC). More than 11 groups of Dermatophagoides ALLERGENS have been defined. Group I allergens, such as Der f I and Der p I from the above two species, are among the strongest mite immunogens in humans.

Earth or other matter in fine, dry particles. (Random House Unabridged Dictionary, 2d ed)

A plant genus of the family POACEAE that contains the Poa p Ia allergen and allergen C KBGP.

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