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To compare the effect on blood retinal barrier disruption 3 and 12 months after implantation of either a blue light filtering intraocular lens(blue-filtering IOL) or an ultraviolet light filtering intraocular lens(UV-filtering IOL).
The following parameters were measured for evaluation of blood retinal barrier disruption.
- the incidence of macular leakage by fluorescence angiography (FA)
- the mean fluorescein concentration in the vitreous by fluorophotometry (VFP)
- the thickness of the macula by optical coherence tomography (OCT)
- the incidence fo macular leakage decreased significantly from 24%(3 months) to 5% (12 months) in the blue-filtering IOL group (P<0.05), and was significantly lower compared with the UV-filtering IOL group at 12 months.
- the VFP significantly decreased in both group from 3 to 12 months.
- the OCT decreased from 175 (3 months) to 166 um (12 months) in the blue- filtering IOL group.
Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
to Compare the Effect of Two Types of IOLs
intraocular lens implantation
Showa University Hospital
Published on BioPortfolio: 2014-08-27T03:34:38-0400
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Insertion of an artificial lens to replace the natural CRYSTALLINE LENS after CATARACT EXTRACTION or to supplement the natural lens which is left in place.
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The portion of the crystalline lens surrounding the nucleus and bound anteriorly by the epithelium and posteriorly by the capsule. It contains lens fibers and amorphous, intercellular substance.
Incomplete rupture of the zonule with the displaced lens remaining behind the pupil. In dislocation, or complete rupture, the lens is displaced forward into the anterior chamber or backward into the vitreous body. When congenital, this condition is known as ECTOPIA LENTIS.
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