Advertisement

Topics

VEGF as a Prognostic Factor for White Matter Damage in Preterm Infants

2014-08-27 03:34:53 | BioPortfolio

Summary

We hypothesize that misexpression of vascular endothelial growth factor (VEGF) in the CSF of preterm infants can be used as a biomarker to predict the risk for developming white matter damage.

Study Design

Time Perspective: Prospective

Conditions

Preterm Infants With White Matter Damage

Status

Not yet recruiting

Source

Hadassah Medical Organization

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:34:53-0400

Clinical Trials [1919 Associated Clinical Trials listed on BioPortfolio]

Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental Outcome

Preterm and very preterm infants are at risk of developing encephalopathy of prematurity and long-term neurodevelopmental delay. Magnetic resonance imaging (MRI) allows the characterizatio...

Pharmacological Recruitment of Endogenous Neural Precursors to Promote Pediatric White Matter Repair: Establishing Correlations Between Visual Outcomes, Saccadic Function and MEG Oscillations in Children With Demyelinating Disorders in Comparison to Healt

The neural circuits in our brains require a layer of insulation in order to transmit signals in a rapid and efficient fashion. This insulation is called White Matter and is comprised of a ...

Brain Networks and Mobility Function: B-NET

Rapidly accumulating evidence indicates that the central nervous system (CNS) plays a pivotal role in mobility function with age-associated CNS changes strongly contributing to declining m...

Meningeal Inflammation on 7T MRI as a Tool for Measuring and Predicting Ocrelizumab Response in Multiple Sclerosis

Multiple Sclerosis (MS) is an autoimmune disorder of the central nervous system. In MS, inflammation is known to attack areas of the brain, spinal cord, and optic nerves; resulting in disa...

The Relationship Between Right-to-left Shunt and Brain White Matter Lesions in Patients With Migraine

The purpose of the study is to evaluate the prevalence of white matter lesions in Chinese migraineurs with and without right-to-left shunt. The aim is to study the relationship among right...

PubMed Articles [9256 Associated PubMed Articles listed on BioPortfolio]

The optimal choices of animal models of white matter injury.

White matter injury, the most common neurological injury in preterm infants, is a major cause of chronic neurological morbidity, including cerebral palsy. Although there has been great progress in the...

Accelerated Small-World Property of Structural Brain Networks in Preterm Infants at Term-Equivalent Age.

The prediction of neurodevelopmental outcomes in preterm infants is one of the clinical challenges of pediatrics. Despite the recent interest in brain development and white matter connectivity using a...

Circular RNA Expression in the Brain of a Neonatal Rat Model of Periventricular White Matter Damage.

Periventricular white matter damage (PWMD) is the predominant neurologic lesion in preterm infants who survive brain injury. In this study, we assessed the global changes in and characteristics of the...

White matter microstructure is associated with language in children born very preterm.

Very preterm birth is associated with altered white matter microstructure and language difficulties, which may compromise communication, social function and academic achievement, but the relationship ...

Early breast milk exposure modifies brain connectivity in preterm infants.

Preterm infants are at increased risk of alterations in brain structure and connectivity, and subsequent neurocognitive impairment. Breast milk may be more advantageous than formula feed for promoting...

Medical and Biotech [MESH] Definitions

A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.

Striped gray and white matter consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the thalamus in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The white matter is the internal capsule.

The region of CENTRAL NERVOUS SYSTEM that appears lighter in color than the other type, GRAY MATTER. It mainly consists of MYELINATED NERVE FIBERS and contains few neuronal cell bodies or DENDRITES.

Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)

Region of CENTRAL NERVOUS SYSTEM that appears darker in color than the other type, WHITE MATTER. It is composed of neuronal CELL BODIES; NEUROPIL; GLIAL CELLS and CAPILLARIES but few MYELINATED NERVE FIBERS.

More From BioPortfolio on "VEGF as a Prognostic Factor for White Matter Damage in Preterm Infants"

Advertisement
Quick Search
Advertisement
Advertisement

 

Searches Linking to this Trial