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Effect of EGb 761® on Patients With Mild to Moderate Alzheimer's Disease

2014-08-27 03:37:23 | BioPortfolio

Summary

The aim of this study is to measure the effect of EGb 761® versus placebo on the ratio of the isoform of the protein precursor of beta amyloid platelets, in patients with mild to moderate Alzheimer's disease.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Alzheimer Disease

Intervention

EGb 761® (Tanakan®)

Location

Hôpital La Timone
Marseille
France
13 005

Status

Terminated

Source

Ipsen

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:37:23-0400

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Abnormal structures located chiefly in distal dendrites and, along with NEUROFIBRILLARY TANGLES and SENILE PLAQUES, constitute the three morphological hallmarks of ALZHEIMER DISEASE. Neuropil threads are made up of straight and paired helical filaments which consist of abnormally phosphorylated microtubule-associated tau proteins. It has been suggested that the threads have a major role in the cognitive impairment seen in Alzheimer disease.

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