Clinical Trials About "Zimmer Biomet surpasses estimates maintains short term priorities" - Page: 2 RSS

03:00 EDT 19th October 2019 | BioPortfolio

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Showing "Zimmer Biomet surpasses estimates maintains short term priorities" Clinical Trials 26–50 of 12,000+


E-aid Cognitive Behavior Therapy for Insomnia to Prevent Transition From Short-term to Chronic Insomnia in China

Short-term insomnia is one of the most common sleep disorders. Online cognitive behavioral therapy for insomnia (e-aid Cognitive Behavioral Therapy for Insomnia, eCBTI) has received wide attention in recent years. Foreign countries already have some eCBTI treatment tool, shown similar efficacy as standard CBTI, but how eCBTI can help in short-term insomnia disorders require further exploration and examination. In this study, Investigators will establish eCBTI treatment tool to...

Machine-Generated Mortality Estimates and Nudges to Promote Advance Care Planning Discussion Among Cancer Patients

This study will use a stepped-wedge cluster randomized trial to evaluate the effect of a health system initiative using machine learning algorithms and behavioral nudges to prompt oncologists to have serious illness conversations with patients at high-risk of short-term mortality.

Short-Term Fasting: Impact on Toxicity

This is a study to determine the safety and feasibility of short-term fasting prior to administration of combination chemotherapy with gemcitabine and cisplatin in patients with advanced urothelial and pulmonary malignancies. The study will evaluate the toxicity profile of standard gemcitabine and cisplatin chemotherapy in subjects who eat normally compared to those who undertake short-term fasting. The investigators hypothesize that fasting will reduce the incidence of signifi...

Computer-Assisted Total Knee Arthroplasty (TKA) With Zimmer LPS Flex Knee System

To determine clinical outcomes and biomechanical gait performance of patients who receive the Zimmer Legacy® LPS Flex Knee system using a computer-assisted surgical technique. This study will provide evidence as to whether there are differences between the two surgical procedures with respect to complications such as infection and dislocations, rate and level of functional recovery, blood loss, operating time, degree of radiographic correction and quality and duration of post...

Short-term Starvation vs. Normal Diet Before Chemotherapy of Solid Tumors

Recent pre-clinical data provide strong evidence that short-term starvation before the administration of cytostatic drugs for the chemotherapy of solid tumors leads to significantly higher efficacy and lower toxicity levels. However, these findings have so far not been validated in patients. The aim of this trial is to provide first clinical evidence regarding the impact of pre-chemotherapeutic short-term starvation on response to therapy (primary endpoint). Additionally, progr...

Post Market Clinical Follow-Up of the Zimmer Stafit Acetabular System

This study is a Post Market Clinical Follow up study to fulfil the post market surveillance obligations according to Medical Device Directive and European Medical Device Vigilance System (MEDDEV) 2.12-2. The data collected from this study will serve the purpose of confirming safety and performance of the Zimmer Stafit Acetabular System.

Effects of Structured Simplified Short-term Intensive Insulin Therapy on Long-term Glycemic Remission

Short-term intensive insulin therapy is shown to induced glycemic remission, but traditionally patients were hospitalized for 2-4 weeks in order to receive the therapy, the long inpatient period precluded the wide application of the thrapy. This study aims to invesitgate whether simplified regimen is non-inferior to traditional regimen in achieving long-term glycemic remisson.

Short-term Effect of Positioning Cushions and Harmonic Techniques on Paratonia in Persons With Dementia

This study investigated the short-term effect of both harmonic techniques and supporting cushions on muscle tone, range of motion, pain and daily care activities in 22 patients with moderate to severe paratonia. The study consisted of two parts, each part was conducted during one week. In the first part of the study the short-term effect of supporting cushions was examined; in the second part of the study the additional short-term effect of harmonic techniques was investigated.

Zimmer CAS PSI X-Ray Knee in TKA (Total Knee Arthroplasty)

The objective of the observational study is to assess the positioning of customized guides designed from patients X-Rays (Zimmer® X-Ray PSI Knee) using optical navigation in primary total knee arthroplasty.

Short Message Service (SMS) Impact on Patient Compliance Receiving Long Term Lipid Lowering Therapy With Statins

The objective of the study is to determine whether short text massages could be used successfully as a compliance aid and improve clinical outcomes in long term lipid lowering therapy.

Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia

- To determine whether the success rate with drug treatment (atropine) of amblyopia due to strabismus or anisometropia in patients less than 7 years old is equivalent to the success rate with occlusion (patching) therapy - To develop more precise estimates of the success rates of amblyopia treatment - To identify factors that may be associated with successful treatment of amblyopia - To collect data on the course of treated amblyopia to provide more preci...

Prognosis and Survival Estimates in Palliative Therapy

The accuracy of clinical survival estimates is tested in comparison to objective prognostic scores.

An Open Label Comparing the Short Term Efficacy of Lacrisert

To evaluate the short term effects of LACRISERT®. upon fluorescein corneal staining, tear osmolarity and surface topography in human subjects with dry eye disease.

Naltrexone Maintenance Treatment of Alcoholism

The purpose of this study is to determine the long-term effectiveness of naltrexone treatment in alcohol-dependent patients who respond to short-term treatment. Those who respond to short-term treatment will be randomized to a 1-year, double-blind, placebo-controlled maintenance phase with a 6-month posttreatment followup.

Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power

This study will examine the short-term cardiovascular (CV) effects of e-cigarette device power in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=21). The specific aim is to determine the impact of e-cigarette power on nicotine pharmacology, systemic exposure to toxic volatile organic compounds (VOCs), and short-term cardiovascular effects.

Evaluation Of Different Rapid Orthodontic Expansion Devices

Evaluating and comparing the short term effects of different palatal expanders on the amount of palatal expansion and buccal tipping of posterior teeth. Hypothesis: H0: There is no difference in the short term effects between the different palatal expanders. H1: There is a significant difference in the short term effects between the different palatal expanders.

PRE-COG Validation to Predict the Risk of Hospitalization of Discharged Patients With Schizophrenia in the Short Term.

The purpose of this study is to establish and validate a scale/model that can be used in the evaluation of the duration of time and factors between short term hospital treatment and subsequent relapse periods in patients with schizoaffective/schizophreniform disorders.

The Effect of Short Term Amiodarone Treatment After Catheter Ablation for Atrial Fibrillation

The purpose of this study is to examine the overall effectiveness of short-time anti-arrhythmic drug treatment with amiodarone (to control heart rhythm) to prevent short-and long-term atrial fibrillation following an ablation procedure for atrial fibrillation.

Cochlear Promontory Stimulation for Treatment of Tinnitus

Tinnitus is the perception of sound when no external noise is present. The Center for Disease Control (CDC) estimates over 50 million - nearly 15% of the general public -experience some form of tinnitus. Roughly 20 million people struggle with burdensome chronic tinnitus, with 2 million experiencing extreme and debilitating symptoms. The 2014 Clinical Practice Guideline on tinnitus from the American Academy of Otolaryngology - Head and Neck Surgery summarized the existing stat...

Patient-Centered Risk Adjusted Surveillance After Curative Resection of Colorectal Cancer

The long-term goal of this research is to develop new tools to guide patients, caregivers, and clinicians in making individualized decisions regarding colorectal cancer (CRC) surveillance. As part of a Patient-Centered Outcomes Research Institute-funded contract, principal investigator will analyze surveillance data to determine the effectiveness of CRC surveillance and recurrence risk taking into account different patient and tumor characteristics; identify key issues about CR...

Expectations and Priorities of Elderly Patients for a First Medical Treatment for Cancer

The main objective of study is to describe the priorities of elderly patients (70 years and over) undergoing a first medical treatment for cancer, at initiation of treatment and after 3 months of treatment. The main criterion is a prioritization of 4 items per patient from a list of 8 expectations regarding the objectives of their treatment: treatment efficacy, life expectancy, autonomy, daily activities, social activities, heaviness of treatment, toxicity, economics.

Long-Term Study of Living Kidney Donors

Kidney transplantation, is the preferred treatment option of end stage renal disease. Compared to dialysis, patients who receive kidneys have a 70% reduction in death, a dramatically improved quality of life and cost the health care system considerably less. As a result, there are over 3000 Canadians on the waiting list for a kidney. In order to meet the shortage of cadaveric kidneys, the rates of living kidney donation have nearly doubled over the last 10 years. Yet despite...

Intensive Short-Term Dynamic Psychotherapy (ISTDP) in the Emergency Department

Objective: Somatization of emotions accounts for excess Emergency department (ED) visits. Intensive Short-term Dynamic Psychotherapy (ISTDP) has methods to diagnose and manage somatization. We examined the feasibility, acceptability and effectiveness of ISTDP diagnostic and treatment methods used for patients with repeated ED presentations for medically unexplained physical symptoms (MUS)

Enhancing Adjustment to Parental Cancer: Short-term Counselling for Families

A parental cancer diagnosis challenges the family's stability and the parent-child relationship. It may impact the children's well-being, so that about one third of them develop clinically relevant levels of psychological distress. Psycho-oncological family-based counselling programs have been shown to elevate children's and parents' well-being. However, there is still a dearth of familial health services in Switzerland, which has also been recognized by the Swiss National Canc...

Risk of Chronic Kidney Disease Progression

While there are proven therapies that slow CKD progression, these therapies can at times be harmful and costly. The ability to accurately predict the risk of CKD progression to ESRD would be extremely valuable. The short term versus lifetime risk of CKD progression should be taken into account when making risk based clinical decisions. In a representative CKD practice, we compared the short term and lifetime risk assessment in our stage 3 CKD patients to determine whether decis...

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