Clinical Trials About "Neural networks everywhere" - Page: 3 RSS

17:12 EST 13th December 2018 | BioPortfolio

We list hundreds of Clinical Trials about "Neural networks everywhere" on BioPortfolio. We draw our references from global clinical trials data listed on and refresh our database daily.

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Showing "Neural networks everywhere" Clinical Trials 51–75 of 1,000+


Cause and Consequence of Neural Fatigue

While the scientific community understands quite well why muscles ache after prolonged exercise, the origins of mental fatigue remain totally mysterious. Existing theories remain at a psychological level, with scarce supporting evidence. Mental fatigue typically occurs after long episodes during which humans exert control on motor or cognitive processes, instead of executing routine or stimulus-driven behaviours. However, work organization (especially in risky job like airplane...

Study of Functional Networks in Resting fMRI

The primary purpose is to compare with resting fMRI the functional networks of rest (RTS) in unipolar depression and in bipolar depression. Hypothesis : the main objective of this work is to compare with the rest fMRI the Rest Functional Networks (RFN) in the unipolar depression and in the bipolar depression in order to identify specific biomarkers for each affection. The general hypothesis of this work is that intra- and inter RFN connectivity is different between bipolar pat...

Finding the Right Words in Neurogenic Communication Disorders

Every year thousands of persons suffer from brain damage resulting in anomia, that is, word finding difficulties affecting their ability to talk to other people. Anomia may be a result of stroke or of progressive neurological diseases such as Parkinson's disease or multiple sclerosis (MS). Word retrieval is dependent on a complex system of different neural networks and to name objects and activities can be affected to different degrees. The present project explores different as...

Post-stroke Immunological Changes in Younger Stroke Patients

In the present study, the investigators aim to elucidate the role of T-cells on cognitive decline in younger stroke patients, using repeated cognitive testing, brain imaging, and immunological analyses in the first 9 month after stroke. The examiners will investigate (i) the extent and duration of stroke-induced changes in T cell function within the peripheral blood of patients; (ii) changes within the cytokine spectrum in cerebrospinal fluid, and (iii) post-stroke cognitive fu...

Neural Correlates of Driving and Cannabis

Driving is a set of complex tasks and requires use of multiple cognitive domains, including attention, planning, and memory. In laboratory studies, the main psychoactive component in cannabis, delta-9-tetrahydrocannabinol (THC), was shown to impair short-term memory, attention, reaction time, tracking, and coordination, resulting, for instance, in significantly more deviations from the lane and increased break latency. Surveys and epidemiological studies suggest that cannabis c...

Neural Stem Cells Therapy for Cerebral Palsy

To evaluate the safety and efficacy of neural stem cells (NSCs) therapy for cerebral palsy.

Multi-modality MRI Study on Acupuncture Regulates the Default Mode Network in Subjective Cognitive Decline

This project is focused on 60 patients with subjective cognitive decline as the research object, by the multimodal neuroimaging techniques such as resting state in magnetic resonance imaging (fMRI), the arterial spin labeling (ASL) and diffusion tensor imaging (DTI), to observation changes of the white matter fibers from connections, cerebral blood flow perfusion and function integrity, for exploring the neural mechanism of acupuncture modulation in the default mode networks of...

Neural Stem Cell Transplantation in Multiple Sclerosis Patients

This is a phase I study evaluating the feasibility, safety and tolerability of intrathecally administered human Neural Stem Cells (hNSCs), at an escalating dose ranging from 0.7x10^6±10% cells to 5.7x10^6±10% cells/kg of body weight, in patients affected by Progressive Multiple Sclerosis

Comparison of Neural Mobilization Techniques to Standard Care Treatment in Patients With Lumbar Radiculitis

The purpose of this study is to determine the effectiveness of neural mobilization techniques compared to standard care treatment in patients with lumbar radiculitis.

Effectiveness of Cervical Traction and Neural Mobilization in Patients With Cervical Radiculopathy

The purpose of the study is to examine the effects of cervical traction with or without the addition of neural mobilization, in patients with cervical radiculopathy

Investigating Neural Processing of Social Stimuli

The primary goal of the present study is to test whether neural activity in brain regions associated with processing threat and social stimuli may underlie paranoid thinking.

Effect of Neural Mobilization on Lumbosacral Radiculopathy Patients With Peripheral Sensitization

The primary purpose of this study was to investigate the effects of slider and tensioner techniques on pain, hip and knee ROM in lumbosacral radiculopathy patients with peripheral sensitization. A secondary purpose was to evaluate the correlation between these outcomes measurements.

Gait Mate: Examining Neural Networks Engaged During Lower Extremity Movement in the MRI

Less than 50% of stroke survivors progress to independent community ambulation. Even among the stroke survivors who achieve independent ambulation, significant residual deficits persist in balance and gait speed, with 60% of persons post-stroke reporting limitations in mobility related to walking.Consequently maximizing recovery of locomotor function is the focus of neurorehabilitation efforts worldwide. A recently completed clinical trial from members of this investigative tea...

Human Networks for Behaviors Related to the Expectation of Pain.

The conditioned expectation of pain is an important aspect of pain-related disability produced by environments and stimuli associated with a painful injury on the job, although the neuroscience of this expectation is unclear. The mechanisms of expectation of pain will be studied by recording electrical signals through electrodes implanted at sites in the brain during the surgical treatment of epilepsy. These sites will be identified by electrical activity novel connectivity bas...

Effectiveness of an HIV Prevention Program That Targets the Inner Workings of High-Risk Social Networks

This study will determine whether an HIV prevention program that targets the inner workings of social networks at high risk for HIV and other sexually transmitted diseases is effective in reducing frequency of high-risk sexual behaviors among network members.

SLeep and IMagery Correlates

This study is designed to determine the neural networks underlying the sleep-related motor consolidation process following motor imagery practice. While beneficial effects of sleep are expected for sequential movement but not for adaptation motor tasks, the corresponding neuroanatomical correlates have not yet been investigated when participants acquired the motor tasks through mental practice. Data should substantially promote how designing motor imagery interventions targetin...

Use of Neurofeedback to Enhance Attention After Brain Injury

Difficulty to sustain attention over a prolonged period of time is one of the core difficulties experienced by people who have undergone traumatic brain injury. Rehabilitation of attention is often based on compensatory strategies, because of the limited impact of cognitive training on improving attentional capacity after brain injury. New therapeutic approaches to explore the plastic recovery of the brain after injury, and consequent performance improvement, are warranted. ...

The Neural Basis of Oxytocin's Effects on Empathy

The main focus of this study is to examine oxytocin effects on behavioral and neural indices of empathy processing.

Mediators of Atherosclerosis in South Asians Living in America (MASALA) Social Network Study

It has been argued that social relationships are important to health and well-being. This study will investigate links between social networks and cardiovascular disease risk factors in South Asians, the second fastest growing ethnic group in the US and one with disparate rates of coronary heart disease. Identifying and understanding the links between social networks and cardiovascular disease is key to the development and testing of family- and community-level prevention inter...

Effectiveness of a Novel Neural Tissue Management to Improve Short-term Pain and Disability in Patients With Sciatica

Objectives: To analyse the effects of sciatic neural mobilisation, in combination to the treatment of the surrounding structures, on pain and disability. Secondly, to investigate baseline characteristics that may be associated with improvements in pain and lumbar disability. Methods: Twenty-eight patients with a clinical diagnosis of sciatica were treated with neural mobilization, joint mobilisation and soft tissue techniques. Pain intensity and lumbar disability were assessed ...

Neural Biomarkers of Clozapine Response

Clozapine has consistently shown to be a superior drug for psychosis in patients who do not respond to other treatments, but its mechanism of action remains unknown. The overall goal of this study is to examine the functional neural circuitry that underlies successful treatment with clozapine, which may lead to the identification of biomarkers that will allow for more efficient use of clozapine, as well as additional treatment targets for patients with refractory illness.

Neural Dynamics Technique for the Treatment of Chronic Radicular Low Back Pain

Low back pain ( LBP) is a significant health problem which affects about 70%-80% of the population during the course of their life . The majority of LBP is resolved within 3 months; however, up to 40% of LBP becomes chronic. One subgroup of chronic LBP is patients with sciatica. Sciatica is characterized by radiating pain to the buttock and lower limb, with or without low back pain. It has been shown in the upper limb that by positioning the contra-lateral arm in tension ...

Neural Correlates of Self

Despite the increasing popularity of mindfulness meditation and hypnosis in healthcare and in the general community the underlying neurobiological mechanisms are unclear. The change in the relationship between the self and the conscious experience that they bring about may be crucial. This study aims to identify the neural correlates of self-consciousness in meta-awareness and absorption - using functional Magnetic Resonance Imaging (fMRI) in healthy participants combined with ...

Virtual Neuroprosthesis: Restoring a Sense of Touch to Amputees

The overall goal of this project is to develop a virtual neuroprosthesis in which a facsimile of a neural implant is externalized and housed in a well-controlled microfluidic chamber, thereby abating the intrinsic limitations of highly invasive studies with neural implants. Able-bodied and upper limb amputee subjects will be recruited to control a dexterous artificial hand and arm with electromyogram signals while electroencephalogram (EEG) signals are simultaneously measured. ...

CPAP Titration Using an Artificial Neural Network: A Randomized Controlled Study

The purpose of the study is to determine the validity of the prediction model in reducing the rate of CPAP titration failure and in achieving a shorter time to optimal pressure

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