Clinical Trials About "issues emergency exemption banned neonicotinoid insecticide prevent virus∨derfield=score∨derval=desc" - Page: 4 RSS

13:46 EDT 18th July 2019 | BioPortfolio

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Showing "issues emergency exemption banned neonicotinoid insecticide prevent virus" Clinical Trials 76–100 of 10,000+

Thursday 11th July 2019

Effectiveness of Calcium Channel Blockade for OP and Carbamate Pesticide Poisoning

This study evaluates whether the addition of intravenous magnesium sulphate or nimodipine to standard therapy (supportive care plus for all patients atropine and, for OP insecticide poisoned patients, pralidoxime) benefits patients after acute anticholinesterase self-poisoning with OP or carbamate insecticides.

Usefulness of Early Warning Systems in Detecting Early Clinical Deterioration After Intensive Care Discharge

The VitalPac Early Warning Score (VIEWS) scoring system, developed by Prytherch et al., Is an early warning system that aims to predict the first 24-hour mortality in emergency patients. National early warning score (NEWS) is another early warning scoring system recommended by the Royal College of Physicians in London to detect early clinical deterioration in hospitalized patients. The aim of this study was to determine the early clinical deterioration after ICU and hence ...

Exercise With Music for ICU Survivors

This project will test whether the individualized music-enhanced exercise playlist (Exercise with Music intervention) can prevent further physical and psychological deterioration and motivate ICU survivors to more actively participate in their rehabilitation.

Bivalirudin in Elderly Patients With Acute ST-segment Elevation Myocardial Infarction

The study is an investigator-sponsored, prospective, multicenter, randomized, open-label study designed to compare efficacy and safety between bivalirudin and heparin in elderly patients with acute ST-segment elevation myocardial infarction undergoing emergency PCI.

Development of a Risk Score to Predict the Vacuum Extraction Failure

Safe operative vaginal delivery requires a careful assessment of the clinical situation. During the pushing efforts, the complexity of the delivery can lead to choose between an operative vaginal delivery attempt and a caesarean section straightaway. An emergency caesarean section for failed operative vaginal delivery is associated with a higher fetal and maternal morbidity, compared to a successful operative vaginal delivery and to a caesarean section straightaway. The...

Thrombin Generation as a New Test for Anticoagulation Management in Patients With ECMO

ECMO (Extracorporeal Membrane Oxygenation) is a circulatory assistance device aiming at maintaining or restoring cardiopulmonary circulation. Complications of this device are mainly hemorrhagic, related to coagulopathy induced by the initial pathology or by the device itself, or thrombotic and ischemic. One of the major challenges is therefore the management of a suitable curative anticoagulation, sufficient to limit the activation of hemostasis du to the ECMO, but reasonable t...

Wednesday 10th July 2019

Junior Emergency Physician Learning Curve to Perform Transcranial Doppler on Brain-damage Patients

Transcranial Doppler is a noninvasive tool. Using velocity measurements and pulsatility index it allows the evaluation of cerebral haemodynamics. In patients presenting brain injury cerebral perfusion may be impaired. Indirect cerebral blood flow can be monitored and risk of neurological worsening can be detected using transcranial Doppler. Education and performance of emergency physicians must be evaluated on brain-injured patients because this tool is operator dependent. The ...

Bivalirudin With Prolonged Full Dose Infusion Versus Heparin Alone During Emergency PCI

This study is aimed to investigate if the bivaliruding with prolonged full dose infusion after PCI is superior to heparin alone in reducing 30-day mortality or major bleeding for patients with STEMI treated with emergency PCI. A total of 6000 STEMI patients will be enrolled and randomly assigned to receive bivalirudin or heparin during emergency PCI in a 1:1 ratio. This study will provide key evidence for peri-operative anticoagulant therapy decisions in STEMI patients.

The Role of High-flow Nasal Cannula Therapy in the Treatment of Acute Carbon Monoxide Poisoning

The aim of the study is to test whether oxygen therapy delivered through high-flow nasal cannula devices in patients admitted to the emergency department for acute carbon monoxide poisoning is superior to the non-rebreathing oxygen face mask therapy with a 15 L/minute oxygen flow (currently the first-line therapy), in terms of reduction of carboxyhemoglobin (COHb) concentration and delayed neurological sequelae incidence.

Analysis of In-hospital Emergency Team Calls in a German Tertiary Care University Hospital From 2013 to 2016

A retrospective analysis of 1,664 emergency forms from MET activities, ranging from January 2013 to December 2016. Every MET activation call via the emergency telephone number ("5555") and following emergency treatment was recorded by a standardized documentation form.

Triage Assessment and NEWS-score as Risk Predictor in Older Frailty Adults in the ED

Emergency Department Triage Systems have not been shown to sufficiently recognize frail elderly patients in need of urgent assessment and care. In this prospective, observational study the performance of the 3-level triage system and the National Early Warning Score (NEWS) 2 are assessed (separately and combined) for predicting adverse outcomes in older frailty patients visiting in the ED. Observational data for this study is gathered as part of GAOPS - main study (ClinicalTria...

Quality of Cardiopulmonary Resuscitation Guided by AED vs Telephone-assistance

The aim of this research is to evaluate the quality of the cardioapulmonary resuscitation (CPR) performed by lay people in two different situations: - 1. When a AED is available and the CPR is guided by it. - 2. When a AED is available and the CPR is guided telephonicaly by an emergency call center.

Tracheal Intubation Using Videolaryngoscope vs Fiberoptic Bronchoscope in Patients With Cervical Immobilization

In patients with suspected cervical spine injury, cervical immobilization, such as manual in-line stabilization or cervical collar has been adopted to prevent further neurologic injury due to cervical motion. In these patients, tracheal intubation with direct laryngoscopy is often challenging due to limited mouth opening, neck flexion, and head extension. In this situation, videolaryngoscope and fiberoptic bronchoscope have been used for tracheal intubation in such patients. We...

Geriatric Assessment and Intervention for Older Patients With Frailty in the Emergency Department

Comprehensive Geriatric Assessment (CGA) is an established approach for better detection of frailty-related problems and includes individualized treatment plan with multi-discipline supportive and treating measures for the older frailty patients. However, there is limited evidence of feasibility and efficacy of the CGA when provided in the emergency department setting. In the GAOPS-study the efficacy of the CGA in emergency department setting will be studied by randomize...

Etoposide in the First-line Treatment of Adult EBV-HLH

his study aimed to investigate the efficacy of etoposide as the first line therapy for adult Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.

The Effect of Message Framing on Blood Donation-Study 1

Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. On July 18, 2018 blood stockpile of O-negative and B-negative in Guangzhou Blood Center reached the warning line, and we took measures for emergency recruitment. O-negative and B-negative blood donors whose last donation dates were between January 1, 2015 a...

Mobile Education for Emergency Ultrasound

The investigators aim to investigate the feasibility of using mobile application platform for sonographic education. Junior physicians at the National Taiwan University Hospital will be enrolled in this study. To design and develop a secure mobile application platform (consisting of mobile device and a cloud-based server) for interactive teaching, remote social-based consultation and discussion. The information exchange through the platform carries images and simulated cases. ...

Intubation With TrueFlex Stylet

The protection of the airways in the conditions of emergency medicine is an important element of the rescue procedure. The aim of this study is comparison of endotracheal intubation with and without using the TrueFlex guide in different emergency situations.

Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors

SPK-8016 is in development for the treatment of patients with inhibitors to FVIII. This Phase 1/2, open-label, non-randomized, dose-finding study is part one of a planned two part study of SPK-8016. Part one will evaluate the safety, efficacy, and tolerability of SPK-8016 in adult males with clinically severe hemopihilia A and no measurable inhibitor against FVIII. Data obtained from Part 1 will inform the study design and dose selection for Part 2 in patients with FVIII inhibi...

Preventing Age-Related Weight Gain in the Workplace With Daily Weighing

To examine the effectiveness of daily weighing to prevent age-related weight gain.

"Early TIPS" Versus Glue Obliteration to Prevent Rebleeding From Gastric Varices

The primary objective of the study is to demonstrate the superiority of an "early tips" strategy over standard treatment by glue obliteration (G0) in preventing bleeding recurrence or death at one year after a non GOV1 gastric variceal bleeding in cirrhotic patients initially treated by GO.

Contingency Management for Alcohol Use Disorder

Randomized pilot study of a device (smartphone app) that poses non-significant risk to participants and is exempt from Investigational Device Exemption regulations [21 Code of Federal Regulations 812.2(c)

A Multimodal Exercise Program in Musculoskeletal System of the Community Elderly

The number of elderly has been increasing in recent decades. Current studies focused on the risk factors of poor physical performance, poor daily activity performance, and even disability in the elderly. We planned to evaluate the physical performance of elderly dwelling in the community and designed a multimodal exercise program which can improve physical performance, prevent disability and promote quality of life.

Safety, Tolerability, Pharmacokinetic Characteristics of hzVSF-v13 in Healthy Male Volunteers

To investigate the safety/tolerability and pharmacokinetic characteristics after single intravenous (IV) administration of hzVSF-v13 (humanized Virus Suppressing Factor-variant 13) in healthy male volunteers

Safety Issues and SurvIval For Medical Outliers

Each Investigator will have to record data concerning 70 patients. In particular 40 patients "outliers" and 30 patients "control".

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