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Clinical Trials About "Efficacy, Safety, and Tolerability Study of RP-G28 in Subjects With Lactose Intolerance" RSS

00:15 EDT 19th July 2019 | BioPortfolio

We list hundreds of Clinical Trials about "Efficacy, Safety, and Tolerability Study of RP-G28 in Subjects With Lactose Intolerance" on BioPortfolio. We draw our references from global clinical trials data listed on ClinicalTrials.gov and refresh our database daily.

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We have published hundreds of Efficacy, Safety, and Tolerability Study of RP-G28 in Subjects With Lactose Intolerance news stories on BioPortfolio along with dozens of Efficacy, Safety, and Tolerability Study of RP-G28 in Subjects With Lactose Intolerance Clinical Trials and PubMed Articles about Efficacy, Safety, and Tolerability Study of RP-G28 in Subjects With Lactose Intolerance for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Efficacy, Safety, and Tolerability Study of RP-G28 in Subjects With Lactose Intolerance Companies in our database. You can also find out about relevant Efficacy, Safety, and Tolerability Study of RP-G28 in Subjects With Lactose Intolerance Drugs and Medications on this site too.

Showing "Efficacy Safety Tolerability Study Subjects With Lactose Intolerance" Clinical Trials 1–25 of 50,000+

Extremely Relevant

Efficacy, Safety, and Tolerability Study of RP-G28 in Subjects With Lactose Intolerance

RP-G28 is being investigated for treatment of moderate to severe lactose intolerance and its potential to improve the tolerance of lactose (dairy products).


Evaluation of Efficacy, Durability, Safety, and Tolerability of RP-G28 in Patients With Lactose Intolerance

Ritter Pharmaceuticals, Inc. is developing RP G28 as a treatment for Lactose Intolerance. Lactose intolerance is a syndrome of gastrointestinal symptoms resulting from a deficiency in intestinal lactase relative to the amount of lactose consumed. Efficacy of RP-G28 will be evaluated by the reduction of lactose intolerance-associated symptoms. The primary objective of this study is to assess the efficacy of RP G28 compared to placebo on symptom reduction related to lactose intol...

Evaluation of the Efficacy, Durability, Safety, and Tolerability of RP-G28 in Patients With Lactose Intolerance

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study conducted in the United States (US) to assess the efficacy of RP-G28 compared to placebo on symptom reduction related to lactose intolerance.


Effectiveness, Safety and Tolerability Study of Two RP-G28 Dose Regimens for Symptoms Associated With Lactose Intolerance

This is a Phase 2 study designed to assess the ability of RP-G28 to improve lactose digestion and tolerance.

Amount of Lactose Causing Symptoms in Lactose Intolerant People

The hypothesis underlying this study is that failure to recognise the role of lactose intolerance among patients has led to inappropriate dietary advice and treatment with drugs that contain lactose as a filler. These failures exacerbate symptoms and lead to the unnecessary use of immune suppressant drugs. This study will identify the threshold at which symptoms of lactose intolerance develop, to provide appropriate advice and treatment in the management of patients.

Amount of Lactose Causing Symptoms in People With Lactose Intolerance and Ulcerative Colitis

The hypothesis underlying this study is that failure to recognise the role of lactose intolerance among patients with ulcerative colitis has led to inappropriate dietary advice and treatment with drugs that contain lactose as a filler. These failures exacerbate symptoms and lead to the unnecessary use of immune suppressant drugs. There is disagreement amongst researchers regarding the amount of lactose needed to cause symptoms in those who are lactose intolerance. The general ...

Prevalence of Lactose Intolerance Following Stem Cell Transplantation

It is currently assumed that all patients are lactose intolerant post bone marrow transplantation. This pilot study is to assess what the incidence of lactose intolerance is after bone marrow transplantation in children. This will be done using a lactose breath test.

Evaluation of LacTEST for the Diagnosis of Hypolactasia in Adults and Elderly Patients Presenting With Clinical Symptoms of Lactose Intolerance

The purpose of this study is to evaluate both the impact of LacTEST on diagnostic thinking and on patient management, and its reproducibility (Test-Retest), for the diagnosis of hypolactasia in adults and elderly patients presenting with clinical symptoms of lactose intolerance.

Validation of a Home-Screening Test for Lactose Intolerance

The hypothesis underlying this study is that whilst there is no home-screening test for lactose intolerance, this test would have significant value as lactose tolerance tests and breath hydrogen tests are expensive and time consuming. Therefore, it would be highly beneficial to validate a simple home-screening test. This study will validate a simple home-screening test that uses lactose and not milk.

Whole Milk Intake and Cardio-metabolic Risk Factors

Milk is the source of high-quality protein, calcium, and other vitamins and minerals. Epidemiologic studies have linked high consumption of milk with risk of metabolic syndrome, T2DM, hypertension and obesity, which are independent risk factors of cardiovascular disease. However, milk contains disaccharide lactose, which may cause gastrointestinal problems in those adults with poor digestion. Recent studies have shown that subjects with intolerance to lactose tend to reduce the...

Association Between Lactase Deficiency, and the Small Intestinal Microbiome in Adults.

The purpose of this study is to study the role of the enzyme (substance produced by the body that helps in a biochemical reaction like digestion in the body) responsible for digestion of lactose and the role of the gut bacteria (bacteria in the intestine) in producing symptoms of lactose intolerance.

Incidence of Lactose Intolerance Among Self-reported Lactose Intolerant People

This is a 3-sites, double-blinded, randomized, 2X2 cross-over study aiming to compare effects of milk containing only A2 type beta casein versus milk containing both A1 and A2 beta casein proteins on the gastrointestinal symptoms for the health people who self-reported to be lactose intolerant.

β-galactosidase Producing Probiotic Strains to Improve Lactose Digestion

The purpose of this study is to assess that two β-galactosidase Producing Probiotic Strains help improve lactose digestion in subjects with lactose maldigestion.

HYBRID: Hydrogen Breath Test in Lactose Digestion

The purpose of this study is to investigate the effect of a fermented infant formula on lactose digestion in lactose intolerant adults.

Effect of a Standard Meal on the Pharmacokinetic Profile of RP-G28 in Healthy Adult Male and Female Subjects

This randomized, open-label, 2-period, 2-sequence, crossover study is designed to evaluate the effect of a standard meal on the pharmacokinetic (PK) profile of orally administered RP-G28, which is being developed for the treatment of lactose intolerance. The study consists of a screening visit (during the interval from Day 21 to Day -3), baseline/check-in to the clinical research unit (Day -2 to Day -1), 2 treatment periods (Day 1 and Day 3), a 48-hour washout between doses, ch...

Relevant

Effects of Lactose on Fecal Microflora

The genetics of lactase divides the population into 2 phenotypes: Those who can(LP) and those who cannot(LNP)digest lactose. This division may help modify disease risks according to geographic population distribution. At least some of the putative mechanism of risk modification may relate to an effect of undigested lactose on lower intestinal bacteria. The effect may provide for support of beneficial microbes. The amount of lactose reaching the colon is made easier in LNP than ...

Effect of B.Bifidum 900791 Intake in Adult With Hypolactasia and Lactose Intolerance

Lactase is high in the newborn intestine, allowing him to digest the high amounts of lactose present in breastmilk. From weaning, lactase is genetically programmed to decrease, reaching residual levels in the adult. This situation occurs in 75% of the world population and is known as "adult primary hypolactasia" while the remaining 25% is "lactase persistent" i.e. maintains in adulthood lactase values similar to these of newborns. In subjects with hypolactasia, the intake of mi...

Study in Healthy Subjects to Compare Two Tablet Formulations of Memantine (Ebixa®) in Fasted and Fed Conditions

The purpose of this study is to investigate the release of memantine into the bloodstream of two different formulations: one formulation containing lactose and one without lactose.

A Non-inferiority, Multicenter and Randomized, Single-Dose Study About a Treatment to Hypolactasia (LAILAI)

The study primary objective is to compare the clinical efficacy of two formulations in the supportive treatment of lactose intolerance.

The Effect of Probiotics on Lactose Intolerance

Lactose intolerance (LI), also known as lactose malabsorption is the most common type of carbohydrate malabsorption. It is associated with the inability to digest lactose into its constituents, glucose and galactose, due to low levels of lactase enzyme activity (1-2). At birth, lactase activity is at the highest and it declines after weaning (1-2). The unabsorbed lactose is metabolized by colonic bacteria to produce gas (hydrogen (H2) and methane (CH4)) and short chain fatty ac...

Comparing the Digestion of Milk With Different Beta-casein Protein Content by Dairy Intolerant Persons

Persons with dairy intolerance may experience cramps/abdominal pain, bloating, flatulence, acute diarrhea, or fecal urgency when they ingest excessive amounts of lactose. The intensity of these conditions can be mild or severe and likely depends on numerous variables including dose, transit time, intestinal residual lactase activity and microbiome potential to ferment lactose (Haverberg et al, 1980; Johnson et al, 1993; Newcomer et al, 1978; Rask Pedersen et al, 1982; Reasoner ...

Study of FLEXISEQ® for Treatment of Osteoarthritis of the Knee in NSAID-compromised Patients

Primary Objective To substantiate the efficacy of 2.2 g FLEXISEQ® for the treatment of pain related to osteoarthritis (OA) of the knee in patients contraindicated for or with clinical intolerance to NSAIDs. Secondary Objectives - To substantiate the efficacy of 2.2 g FLEXISEQ® for the treatment of stiffness and improvement of joint function in patients contraindicated for or with clinical intolerance to NSAIDs and with OA of the knee. - To subst...

Role of Low Lactose Infant Formula In The Management of Neonatal Abstinence Syndrome

Currently Morphine and or Methadone are the most commonly used drugs in the treatment for NAS along with supportive care. Many care providers offer tolerance "low lactose" formula to these infants to alleviate gastrointestinal symptoms. There are no clinical studies to support this practice and it is currently unknown that low lactose formula really helps or not in management of NAS. This is a Randomized Double Blind Clinical Trial to assess the role of low lactose formula ...

Efficacy, Safety, and PK Study of Ulimorelin in Patients With Enteral Feeding Intolerance: The PROMOTE Trial

The purpose of this study is to evaluate the effect Ulimorelin in patients with enteral feeding intolerance.

Computerized Cognitive Bias Intervention for Intolerance of Uncertainty

This investigation examines the efficacy of a brief, one-session computerized interpretation bias modification paradigm (CBM-I) in the reduction of intolerance of uncertainty. Intolerance of uncertainty is a risk factor for the development and maintenance of various forms of psychopathology.


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