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Clinical Trials About "Late Focus LATE Overlooked Brain Disease" RSS

16:17 EDT 20th September 2019 | BioPortfolio

We list hundreds of Clinical Trials about "Late Focus LATE Overlooked Brain Disease" on BioPortfolio. We draw our references from global clinical trials data listed on ClinicalTrials.gov and refresh our database daily.

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We have published hundreds of Late Focus LATE Overlooked Brain Disease news stories on BioPortfolio along with dozens of Late Focus LATE Overlooked Brain Disease Clinical Trials and PubMed Articles about Late Focus LATE Overlooked Brain Disease for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Late Focus LATE Overlooked Brain Disease Companies in our database. You can also find out about relevant Late Focus LATE Overlooked Brain Disease Drugs and Medications on this site too.

Showing "Late Focus LATE Overlooked Brain Disease" Clinical Trials 1–25 of 28,000+

Extremely Relevant

Brain Imaging Biomarkers of Pathological Brain Aging in Late-life Depression

This study investigates the relationships and differences in PET-MRI brain imaging biomarkers of abnormal aging and behavioral measures in late life depression compared to healthy controls, and evaluates relationships and differences in the same imaging and behavioral measures following electroconvulsive therapy. The study tests the hypotheses that late-life depression will be associated with higher levels of accelerated aging and brain disease biomarkers, and that electroconvu...


Impact of Sleep and Meal Timing on Food Intake Regulation

This study will test the hypothesis that a late sleep (Ls) and/or late meal (Lm) behavioral pattern, with equal sleep duration, will promote positive energy balance and insulin resistance (IR).

Effect of Brain Lesion Severity on Treatment Response in Late-Life Depression

This study will determine the relationship between brain lesion severity, treatment response, and frontal lobe brain function in people with late-life depression (LLD).


Is Gastroesophageal Reflux Really a Potential Risk for the Late Symptoms of Bronchopulmonary Dysplasia?

Bronchopulmonory dysplasia(BPD) is a common condition in the low birth weight infants.Although most of the BPD symptoms improved after a regular treatment in infancy, there are still a few late symptoms left such as the frequent respiratory symptoms, a slower weight gain and even sudden death. These late symptoms have made so much trouble to the healthcare of BPD infants.How to find the risk factors and to reduce the prevalence of these late symptoms becomes necessary. It has b...

Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers

RATIONALE: Gathering information over time about patients' sense of being a burden on their caregiver, and caregivers' sense of burden on themselves, may help doctors learn more about the desire to die in patients with late-stage cancer. PURPOSE: This clinical trial is studying perceptions of burden in patients with late-stage cancer and their caregivers.

Central Glutathione Levels in Women With Late Life Depression: a Cross Sectional Pilot Feasibility Study

Female participants with an episode of late-life depression (LLD) and age-matched control participants with no history of mental disorder will attend a one hour Magnetic Resonance Imaging (MRI). A 3 Tesla MRI scanner will be used to measure levels of glutathione (GSH) in the brain via magnetic resonance spectroscopy (1H MRS).

Safety Study of a Gene Transfer Vector for Children With Late Infantile Neuronal Ceroid Lipofuscinosis

The aim of this study is to treat the signs and symptoms of late infantile neuronal ceroid lipofuscinosis (LINCL), a fatal inherited disease in the brain. This will be accomplished by using delivery of a gene (method called gene transfer) to administer to the brain an experimental drug called AAV2CUhCLN2, a gene transfer vector.

Relevant

Early Versus Late FDG-PET/CT in Bladder Cancer

The aim of this study is to examine if late FDG-PET/CT images after intravenous FDG injection has a higher sensitivity and specificity in detecting local lymph node metastases in patients with muscle invasive BC than FDG-PET/CT images 60 minutes after FDG injection. The latter procedure has been used routinely until now.

A Study to Evaluate the Safety and Effectiveness of WF10 Given to Patients With Late-Stage HIV Disease

The purpose of this study is to see if it is safe and effective to give WF10 to adults with late-stage HIV disease. WF10 is suspected to help the immune system fight infection and slow HIV disease progression.

Treatment of Anxiety in Late Adolescents With Autism

Autism spectrum disorders (ASD) affect approximately 1.1% of late adolescents and young adults, making it one of the most common neurodevelopmental disorders. Comorbid anxiety disorders affect many higher-functioning adolescents and young adults with ASD, causing substantial distress and impairment over and above that caused by an ASD diagnosis alone. While cognitive-behavioral therapy (CBT) is a first-line treatment for anxiety disorders among typically developing late adolesc...

Health Status and Burden of Late Effects in Very Long-term Testicular Cancer Survivors (STANDBY-study)

Depending on disease stage, testicular cancer (TC) treatment consists of an orchidectomy, alone or followed by radiotherapy (RT) or platinum-based chemotherapy (CT). TC survival rates are above 90% nowadays, which results in growing TC survivor population. Because of the long life expectancy of these survivors, prevention or early detection of late treatment effects has become increasingly relevant. Yet known late effects are nephrotoxicity, cardiovascular disease (CVD), second...

The Experience of Older Adults Facing Depression for the First Time in Old Age

Analysis of recent studies show that researchers find it hard to distinguish between Late Onset Depression, a first diagnosed major depressive episode which occurs at old age, and Early Onset Depression, a depressive episode at old age with a history of previous episodes. Since current data, about the phenomenology and etiology of Late Onset Depression, lake conicity it is unclear whether this phenomena should be considered as a distinct subtype of depression. Nevertheless, the...

Brain Abnormalities in Late-Onset Major Depression

The objective of this project is to examine the state of the brain in people over 50 years old suffering from late-onset depression by means of an extensive clinical assessment programme, including magnetic resonance imaging (MRI), neuropsychological testing, neurological examination, eye examination as well as blood and saliva samples. The results are to be compared with results from a control group matched for gender and age.

Research of Systemic Management for Late Preterm Infants Nutrition in China

The purpose of the project is to investigate the status of nutrition management of late preterm infants in the member hospitals in the Beijing association of preterm infants, and set up the systemic management of late preterm infants nutrition, Including parenteral nutrition and enteral feeding. And to compare the differences between before and after the implementation of the systemic management specification, to validate its feasibility and validity.

A Long Term Follow up Study in Late-onset Pompe Disease

This study is to observe the progression of disease in late-onset Pompe disease

Safety and Effectiveness Study of rhGAA in Patients With Advanced Late-Onset Pompe Disease Receiving Respiratory Support

Pompe disease (also known as glycogen storage disease Type II) is caused by a deficiency of a critical enzyme in the body called acid alpha-glucosidase (GAA). Normally, GAA is used by the body's cells to break down glycogen (a stored form of sugar) within specialized structures called lysosomes. In patients with Pompe disease, an excessive amount of glycogen accumulates and is stored in various tissues, especially heart and skeletal muscle, which prevents their normal function....

A Prospective, Observational Study in Patients With Late-Onset Pompe Disease

Pompe disease (also known as glycogen storage disease type II, "GSD-II") is caused by a deficiency of a critical enzyme in the body called acid alpha-glucosidase (GAA). Normally, GAA is used by the body's cells to break down glycogen (a stored form of sugar) within specialized structures called lysosomes. In patients with Pompe disease, an excessive amount of glycogen accumulates and is stored in various tissues, especially heart and skeletal muscle, which prevents their normal...

Long-term Outcome in Late-onset Pompe Disease Treated Beyond 36 Months (ATBIG-Pompe-Study)

Long-term outcome in late-onset Pompe disease treated beyond 36 months (ATBIG-Pompe-Study), a multicenter, multinational, longitudinal, non-interventional observational study in subjects, at least 8 years old, diagnosed with late-onset Pompe disease retrospectively and prospectively collects data to understand clinical progression in terms of muscle and respiratory function, and clinical symptomology treated with alglucosidase alfa more than 36 months in 100 subjects.

A Gene Transfer Study for Late-Onset Pompe Disease

The purpose of this study is to evaluate the safety, tolerability, and efficacy of a single intravenous infusion of SPK-3006 in adults with clinically moderate, late-onset Pompe disease receiving enzyme replacement therapy (ERT). Participants will be treated in sequential, dose-level cohorts.

Effect of Late Dinner on Nocturnal Metabolism

This study examines the impact of routine dinner time versus late dinner time on nocturnal metabolism. Specifically, investigators will examine plasma profiles of free fatty acids, glucose, insulin, triglycerides, and oxidation of dietary fat.

A Placebo-Controlled Study of Safety and Effectiveness of Myozyme in Patients With Late-Onset Pompe Disease

Pompe disease (also known as glycogen storage disease Type II) is caused by a deficiency of a critical enzyme in the body called acid alpha-glucosidase (GAA). Normally, GAA is used by the body's cells to break down glycogen (a stored form of sugar) within specialized structures called lysosomes. In patients with Pompe disease, an excessive amount of glycogen accumulates and is stored in various tissues, especially heart and skeletal muscle, which prevents their normal function....

Associations Between Depression and Cardiovascular Disease - a Study of Patients With Late Onset Depression

Studies show that depression is a risk factor for the development of cardiovascular disease. Furthermore there is an increased occurrence of depression in patients with cardiovascular disease. Among other mechanisms atherosclerosis is believed to play an important part regarding these notable associations between depression and ischemic heart disease. Patients with late onset major depression have an increased number of small lesions found in the white matter of the brain, the ...

Pompe Gene Therapy- Screening for Eligibility

The purpose of this study is to determine eligibility for the future clinical trial of gene therapy in adults with late-onset Pompe disease. This screening protocol will enroll up to 20 adults patients (>=18 yo) with late-onset Pompe disease. Study assessments include review of medical history, vital signs, physical examination, muscle function testing, lung function testing, blood and urine collection, serum pregnancy test and ECG. The study results will be collected t...

GMA and Peri in Moderate-late Preterms

To analyze the relationship between the early diagnosis of cerebral palsy with the risk factors of this pathology in moderate and late premature infants

The Effect of Late Night Meals on Fasting Glucose in Type 2 Diabetes Patients

High fasting glucose is a very common problem in type 2 diabetic patients. The cause is probably glucose production by the liver, known as the "dawn phenomenon". The investigators hypothesize that a late night meal can lower the fasting glucose level by early morning insulin secretion stimulated by the food. In this study the investigators intend to test the effect of different kinds of late night meals on fasting glucose in type 2 diabetic patients.


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