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Clinical Trials About "OptiBiotix strong 2019 agreements convert into revenues" RSS

18:44 EDT 15th September 2019 | BioPortfolio

We list hundreds of Clinical Trials about "OptiBiotix strong 2019 agreements convert into revenues" on BioPortfolio. We draw our references from global clinical trials data listed on ClinicalTrials.gov and refresh our database daily.

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Showing "OptiBiotix strong 2019 agreements convert into revenues" Clinical Trials 1–25 of 1,400+

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Fit and Strong! Plus Comparative Effectiveness Trial

This randomized controlled trial is comparing outcomes of customary Fit and Strong!, to Fit and Strong! Plus, an enhanced version of the program that incorporates weight management. We hypothesize that Fit and Strong! Plus participants will show improved diet behaviors at 2, 6, 12, and 18 months that will be accompanied by a significant 5% weight loss at 6 months and maintained to 18 months, compared to participants in customary Fit and Strong!.


Phase 1-2a Study of EBNA1 Inhibitor, VK-2019, in Patients With Epstein-Barr Virus-positive Nasopharyngeal Cancer

This study is a First-In-Human clinical trial to assess the safety and preliminary efficacy of VK-2019, an orally administered EBNA1 inhibitor, for the treatment of patients with advanced nasopharyngeal carcinoma.

Strong Families Strong Forces: Supporting Active Duty Families With Very Young Children

The purpose of this research is to evaluate the efficacy of the Strong Families Strong Forces Parenting Program compared to a parental self-care (Strong Parents) condition in a sample of 150 Active Duty Families with children ages birth to 5 years.


Basic Hemodynamic Monitoring Reliability During Percutaneous Nephrolithotomy.

This prospective pre and post-quasi-descriptive single group interventional study will be done at urology and nephrology center -Mansoura University during the year 2019, for a 3-month duration, starting 1-2-2019 till 1-4-2019 after approval of IRB (Institutional Review Board) code no R/18.03.103 on 5/5/2018, Mansoura Faculty of Medicine. correlating Basic hemodynamics with noninvasive cardiac output for diagnostic reliability during percutaneous nephrolithotomy hidden bleeding...

Safety and Immunogenicity of Fluzone® Quadrivalent, Flublok® Quadrivalent, and Fluzone® High-Dose, Influenza Vaccines, 2018-2019 Formulations

The primary objectives of this study are: - To describe the immunogenicity of the 2018-2019 formulation of Fluzone Quadrivalent vaccine in children 6 to < 36 months of age and 3 to < 9 years of age, and in adults 18 to < 65 years of age, the immunogenicity of the 2018-2019 formulation of Flublok Quadrivalent vaccine in adults 18 to < 65 years of age, and the immunogenicity of the 2018-2019 formulation of Fluzone High-Dose vaccine in adults ≥ 65 years o...

Safety, Reactogenicity and Immunogenicity of Two Quadrivalent Seasonal Influenza Vaccines (Fluzone(R) or Flublok(R)) With or Without One of Two Adjuvants (AF03 or Advax-CpG55.2) in Healthy Adults

This is a Phase I, randomized, double blinded, clinical trial in up to 240 males and non-pregnant females, 18-45 years of age, inclusive, who are in good health and meet all eligibility criteria. This clinical trial is designed to assess the safety, reactogenicity and immunogenicity of either the 2018/2019 seasonal Fluzone or Flublok Quadrivalent Influenza Vaccine (QIV) manufactured by Sanofi Pasteur (SP) given without adjuvant or with one of two adjuvant formulations, AF03 or ...

Functional Magnetic Resonance Imaging - Synthetic Aperture Magnetometry (fMRI-SAM) and Alzheimer's Disease

The aim of the protocol is to study the resting brain activation profile of 3 groups of people, using a new fMRI procedure, called fMRI-SAM. fMRI-SAM will be applied to 25 Alzheimer's disease (AD) patients, 25 patients suffering from amnestic - mild cognitive impairment (MCI) - a clinical picture which may be a prodromal form of AD - and 60 healthy controls. The first analysis of the data will search differences of brain activation profiles between the 3 groups. In the second s...

Paracetamol Versus Placebo in Conjunction With Strong Opioids for Cancer Pain

National guidelines advocate the use of paracetamol in conjunction with strong opioids for cancer pain, despite a lack of evidence for its efficacy. Work is needed to examine the analgesic benefit of paracetamol in this large patient group. The investigators aim to establish if paracetamol in combination with strong opioids provides superior analgesia for cancer related pain over strong opioids alone.

The Effect of Cinnamon on Ovulation Induction in Women With Polycystic Ovary Syndrome

Title: The effect of cinnamon supplementation on ovulation induction in women with polycystic ovary syndrome, Jeddah 2019: Randomized Double-Blind Placebo-controlled trial Phase: III Population: 118 women with polycystic ovary syndrome will be recruited from Obstetrics and Gynecology clinics in King Abdul-Aziz University Hospital, Jeddah 2019. Subject Participation Duration: Each participant will be followed for three months. Intervention: 2g of cinnamon capsules dail...

Strong Hearts: Rural CVD Prevention

Strong Hearts, Healthy Communities is a research study which aims to reduce cardiovascular disease (CVD), improve quality of life, and reduce CVD related health care costs in rural communities. The investigators' aim is to better understand how changes in lifestyle can affect the health of rural women and others in their communities.

INTERCEPTOR Project: From MCI to Dementia

In the next years a number of phase 2-3 trials which utilize experimental drugs possibly disease modifying for Alzheimer Dementia will reach their conclusion. This dense clinical trials activity has triggered a fundamental question both from Patients and Scientific Communities and Health Authorities/Insurances: on which basis will the new drugs -if effective-be distributed to patients or at-risk population? This question mainly deals with the "MCI prodromal to AD"condition sinc...

Investigating the Effectiveness of a Seasonal Influenza Vaccination Promotion Campaign for Members of a Non-Profit, Community-Based Health Insurance Plan: 2018-2019

• This study will assess the effect of promotional messaging and incentives encouraging influenza vaccination in the Sendero IdealCare policy holders during the 2018-2019 Flu Season. The intervention will consist of influenza vaccination promotion/reminders from Sendero Health Plans to subscribers, including text messages, emails, and tailored direct mail outs, i.e. postcard or a personalized letter, and incentive. The study population consists of approximately 22,500 subscri...

Head Start Family and Child Experiences Survey (FACES 2019)

For over two decades, the Head Start Family and Child Experiences Survey (FACES) has been an invaluable source of information on the Head Start program and the children and families it serves. FACES 2019 is the next phase of this important endeavor, and extends a previously conducted data collection to a new sample of Head Start programs, families, and children. Mathematica Policy Research and its partners, Juárez and Associates, Educational Testing Service, and consultants Ma...

Phase 2 Dose and Formulation Confirmation of Quad-NIV in Older Adults

A Phase 2 trial to confirm the dose and formulation, demonstrate adjuvant effect, and evaluate the safety and tolerability of a single intramuscular injection of Quad-NIV with or without Matrix-M1 adjuvant in healthy adults ≥ 65 years of age. A total of approximately 1375 subjects will be randomized to seven treatment groups to receive Quad-NIV or an active comparator.

2019 National Survey of Early Care and Education

The primary purpose of the 2019 National Survey of Early Care and Education (NSECE) is to provide a comprehensive picture of both the availability and utilization of early care and education (ECE) in the United States. This study builds on the work of the 2012 NSECE which was the first nationally-representative survey of ECE providers, workers, and households with young children in more than 20 years. Multiple policy and programmatic changes affecting the supply and quality of ...

Conversion From MPA to Zortress (Everolimus) for GI Toxicity Post-renal Transplantation

Patients who receive renal transplantation at BJH are placed on triple maintenance immunosuppression, which means that patients take 3 types of immunosuppression drugs to suppress their immune system including tacrolimus, mycophenolate (MPA), and prednisone. However, due to the effects of MPA on the gastrointestinal tract, patients often complain of GI adverse effects. Current practice is to either dose-reduce MPA or convert the patient to an alternative agent, typically Azathi...

Safety and Effectiveness of THIODERM STRONG in the Correction of Nasolabial Folds

This is a prospective, open label, dose-escalating, multicenter clinical investigation to evaluate the safety and effectiveness of THIODERM STRONG in the correction of nasolabial folds. The performance is assessed using the 5-point Nasolabial Folds Severity Rating Scale (NLF-SRS) at Week 12 compared to baseline.

Pragmatic Assessment Study Influenza Vaccine Effectiveness in DoD

A total of 10,650 eligible subjects (or 3,550 subject distributed evenly between the 3 study arms) will be enrolled. eligible subjects will be randomized in 1:1:1 (cell-culture-based vaccine, the recombinant vaccine, or the egg-based vaccine) over two influenza seasons (2018-2019, 2019-2020).

Safety and Efficacy of Dexmedetomidine in Painless Colonoscopy

50 patients who undergo painless colonoscopy from May 1, 2019 to December 30, 2019 will be randomized to two groups: Propofol group: propofol is used as a sedative strategy; Dexmedetomidine group: Dexmedetomidine as a sedative strategy. Compared of comfort and pain score of patients, the occurrence of adverse events and the satisfaction score of endoscopists between two groups. This study aims to investigate whether dexmedetomidine is effectively and safely in Painless Colonosc...

Professional Development Tools to Improve the Quality of Infant and Toddler Care

Mathematica Policy Research, funded by OPRE, ACF, DHHS, will conduct a field test of We Grow Together: The Q-CCIIT Professional Development System. These professional development (PD) tools and the interactive website featuring the materials were developed to promote high-quality caregiver-child interactions in non-parental care settings serving infants and toddlers. This field test aims to: (1) examine changes in caregiver practice that the investigators expect to be associate...

Differential Diagnosis Between Granuloma and Radicular Cyst: Effectiveness of Magnetic Resonance Imaging.

The radiolucent periapical jaw lesions of 34 patients, which were surgically enucleated, were investigated by two radiologists using MRI, based on the same six criteria, to categorize the lesions as granulomas or radicular cysts. After apicoectomies, two oral pathologists (blinded to the radiologist's diagnoses) analyzed all specimens by referring to seven specific parameters and diagnosed the specimens as granulomas or radicular cysts. The inter-rater agreements between the ra...

Clinical Evaluation of the Application of the FilmArray GI Panel in Post-HSCT Diarrhea Patients

This is a prospective single arm study with the study period from June 1st, 2019 to May 31st, 2020. An historical control group will be used in the study, which includes all patients received HSCT but not GI panel detection between June 1st, 2018 to May 31st, 2019. All patients receiving HSCT within the year at SCMC will be enrolled in the study. The stool samples will be collected from each patient at 2-3 time points, including the day before pre-conditioning (T1), 28+-3 days ...

Strong Heart Study Analyses Obesity and Lipoproteins

To examine the relationship of obesity and body fat distribution to lipoprotein concentrations in members of the Strong Heart Study.

Live Long Walk Strong (LLWS) Rehabilitation Program: What Features Improve Mobility Skills

This study is being performed to evaluate the efficacy of the Live Long Walk Strong rehabilitation program in Veterans 50 years and older. This study will also examine the features of the program that contribute to improved gait speed.

International Programs Collaborative Studies Coordinating Center

To continue the work of the Collaborative Studies Coordinating Center (CSCC) on international studies in cardiopulmonary disease epidemiology. The work was being performed under bilateral agreements that the NHLBI had entered into with Russia, The People's Republic of China and Pakistan. The contract provided nutritional, epidemiologic and biostatistical services in support of these studies.


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