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Clinical Trials About "dATS Cumulative Irritation Sensitization" RSS

18:02 EST 23rd February 2020 | BioPortfolio

We list hundreds of Clinical Trials about "dATS Cumulative Irritation Sensitization" on BioPortfolio. We draw our references from global clinical trials data listed on ClinicalTrials.gov and refresh our database daily.

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Showing "dATS Cumulative Irritation Sensitization" Clinical Trials 1–25 of 853

Extremely Relevant

Irritation and Sensitization Study of d-Amphetamine Transdermal System

The study will assess skin irritation as well as sensitization for d-ATS patch in healthy subjects.


Cumulative Irritation Potential of 828 Ointment

Cumulative Irritation Patch Test

Cumulative Irritation Test

The purpose of this study is to determine the cumulative irritation potential of the products listed by the Sponsor.


Relevant

Cumulative Skin Irritation Potential of a New 15 mg Nicotine Patch

An investigation on the cumulative skin irritation potential of a newly developed 15 mg nicotine patch. Evaluation of skin irritation of a newly developed 15 mg nicotine transdermal patch.

A Skin Irritation Assessment of Once-Weekly Corplex™ Donepezil Transdermal Delivery System

A study to assess the skin irritation and sensitization potential of Corplex™ Donepezil Transdermal Delivery System (TDS)

A Phase 1 Study to Evaluate the Skin Irritation Potential of FMX-101 in Healthy Volunteers Using a Cumulative Irritant Patch Test Design

A 21-Day, Randomized, Controlled Study to Evaluate the Skin Irritation Potential of FMX-101 in Healthy Volunteers Using a Cumulative Irritant Patch Test Design

Phase I Study to Assess Irritation, Sensitization and Adhesion of a Novel Ibuprofen 200 mg TEPI Medicated Plaster

This trial will be conducted with the aim to investigate the dermal response (skin irritation, sensitization) and the adhesion of Ibuprofen 200 mg TEPI Medicated Plaster as compared to a Placebo TEPI Plaster in two phases: Induction Phase: multiple dose application of one active and one placebo plaster on 5 consecutive days in which the plasters remain in place for 23 hours ± 30 min a day and Challenge Phase: single dose application of one active and one placebo plaster which...

A Study to Determine the Safety and Sensitizing Potential of HAT1 Topical Products Using Skin Sensitivity Patch Tests

The objective of this clinical study is to assess the irritation and sensitisation potential of HAT1 topical products after repeated patch applications to healthy human participants by following conventional Repeated Insult (HRIPT), Cumulative Irritation (CIT), and Phototoxicity (PT) methodologies under the supervision of dermatologists.

A 21-Day Study to Evaluate the Skin Irritation Potential of CCP-020 (Diacerein 1%) Topical Ointment in Healthy Subjects Using a Cumulative Irritant Patch Test Design

Single center, randomized, controlled, evaluator blinded, within-subject comparison study to evaluate the irritation potential of CCP-020 (Diacerein 1%) topical ointment on normal skin.

To Assess the Cutaneous Irritation and Sensitization Potential of a Cosmetic Facial Product Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Participants

The objective of this clinical study is to assess the irritation and sensitisation potential of a cosmetic test product after repeated semi-occlusive patch applications to healthy human participants by following a conventional HRIPT methodology under supervision of a dermatologist.

Correlation Between Central Sensitization Inventory and Posturographic Data

To investigate the use of balance as a screening tool for Central Sensitization, a condition of the nervous system that is associated with the development and maintenance of chronic pain. This is to be done by comparing the scores of a gold standard screening tool (the Central Sensitization Inventory) with balance data

The Preventive Value of Acupoint Sensitization Based on Stable Angina Pectoris

The investigators used a double-blind single-center randomized controlled trial to explore the prevention value of acupoint sensitization based on stable angina pectoris, so as to verify the hypothesis that "acupoint sensitization by finger pressing in traditional Chinese medicine can alleviate the onset of stable angina pectoris".After the inclusion of eligible patients, the patients were randomly assigned to test their acupoint sensitization value. The first five acupoints in...

Central Sensitization and Outcome of Endometriosis Surgery

This study will evaluate whether the degree of central sensitization as measured by the questionnaire "central sensitization inventory CSI" is related to the outcome of surgical endometriosis treatment

Effects of Duloxetine on Pain Relief After Total Knee Arthroplasty in Central Sensitization Patient

This study aims to compare the effectiveness of duloxetine after total knee arthroplasty in Central sensitization patient. Central sensitization plays an important role in the chronic pain experienced by osteoarthritis patients.Elimination of the nociceptive input from the damaged joint by total joint arthroplasty was not always followed by a complete resolution of symptoms. Patients with high levels of preoperative pain and low pain thresholds had a higher risk of persistent p...

SENOC-I Det Sunda Huset II - Sensitization of Occupants of Water Damaged Buildings.

The study is focussed on two main questions: 1. The importance of dampness of the building and home dust as a factor of the subjects= responses. 2. Can measures used in KLINIR predict the subjects’ responses to the dust? This study therefore was arranged to test the following hypotheses: 1. Does dust in general cause inflammatory/body perceptions through e.g. an irritation symptoms index. 2. Does the dust include effective odorants which aff...

A Clinical Study to Evaluate the Sensitizing Potential of LEO 43204 Gel

This is a randomized, single-center, controlled, within-subject comparison study assessing the sensitization potential of the investigational product, LEO 43204 gel under open conditions in healthy volunteers. LEO 43204 Gel and Vehicle Gel will be applied to adjacent sites on the infrascapular area of the back. Evaluation of dermal reactions at the application sites will be assessed clinically using a visual scale that rates the degree of erythema, edema and other signs of ...

To Assess the Photosensitisation and Photoallergy Potential of a Cosmetic Facial Product in Healthy Participants

To evaluate the skin irritation and sensitization potential of a cosmetic facial product, under exaggerated conditions of use with controlled product application and under supervision of a dermatologist.

Dyspareunia and Central Sensitization

Background: Endometriosis affects 10% of reproductive aged females, and can have a negative impact on sexual quality of life. Endometriosis can cause pelvic pain with deep penetration during intercourse, as well as other sexual and non-sexual pains. This study will allow us to determine if an increase in sexual pain is related to central sensitization. Purpose: The purpose of this study is to determine if there is an association between the severity of sexual pain and central ...

Effect of High-dose Naloxone Following Third Molar Extraction

Recent studies have focused on the role of endogenous opioids on central sensitization. Central sensitization is known to be impaired or altered in chronic pain conditions, as fibromyalgia or chronic tension headache. Animal studies have shown reinstatement of mechanical hypersensitivity following naloxone administration after resolution of an injury. This suggests latent sensitization. In the present study, investigators hypothesize that a high-dose target-controlled naloxone...

Predominant Sensitizations to Single Bee Venom Allergens as a Risk Factor for Therapy Failure

Venom immunotherapy (VIT) is an established treatment for Hymenoptera venom allergy and provides long-term protection from further generalized reactions in almost all patients. However, it is still unclear why bee VIT is less effective than vespid VIT. The preliminary data show that not only predominant Api m 10 sensitization but also other predominant sensitizations may be relevant as risk factors for treatment failure. Interestingly, all patients with a predominant Api m 10 ...

An Irritation Study With New Calcipotriol Ointment Formulations in Healthy Subjects

The purpose of this trial is to compare the skin irritation potential of eight different formulations of vitamin D analogues after repeated applications on intact skin of healthy subjects.

Clinical Protocol of Sensitized Acupoint Changes in KOA Patients

Based on the research background and the preliminary research basis of the research group, in order to answer the material basis and micro-physical environment change characteristics of KOA sensitization acupoints and provide scientific basis for in-depth study of sensitization of acupoints. This study plans to use knee osteoarthritis as a research vehicle, and use microdialysis combined with high performance liquid chromatography to analyze the local material basis and key ind...

Biodiversity Intervention and Atopic Sensitization

Children will receive biodiversity intervention or placebo. The proof of concept trial is double blind. Intervention will start at the age of 2 months and last 10 months. Children will be randomized to arms. IgE sensitization is the primary outcome.

Evaluation of the Irritation Potential of Products in Human Eyes

To evaluate the human eye irritation potential of one test sunscreen formulation.

Sensitization Study of ATx201 in Healthy Volunteers

This is a Phase I, single-site study to evaluate the sensitization potential of topically applied ATx201 GEL, 2% and 4%, along with a placebo control, in healthy human subjects.


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