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Clinical Trials About "Amantadine Cocaine Related Disorders" RSS

21:24 EDT 23rd October 2018 | BioPortfolio

We list hundreds of Clinical Trials about "Amantadine Cocaine Related Disorders" on BioPortfolio. We draw our references from global clinical trials data listed on ClinicalTrials.gov and refresh our database daily.

More Information about "Amantadine Cocaine Related Disorders" on BioPortfolio

We have published hundreds of Amantadine Cocaine Related Disorders news stories on BioPortfolio along with dozens of Amantadine Cocaine Related Disorders Clinical Trials and PubMed Articles about Amantadine Cocaine Related Disorders for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Amantadine Cocaine Related Disorders Companies in our database. You can also find out about relevant Amantadine Cocaine Related Disorders Drugs and Medications on this site too.

Showing "Amantadine Cocaine Related Disorders" Clinical Trials 1–25 of 13,000+

Extremely Relevant

Effectiveness of Amantadine and Propranolol for Treating Cocaine Dependence - 2

Cocaine addiction is a serious health problem with no available medical treatment for preventing relapse. Amantadine, a medication that improves muscle control, and propranolol, a medication that lowers blood pressure, may be useful in treating cocaine addiction in individuals with severe cocaine withdrawal symptoms. This study will evaluate the effectiveness of amantadine and propranolol in preventing drug relapse among cocaine addicts.


Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4

The purpose of this study is to empirically test a series of medications to: 1) determine each medication's efficacy in treatment of cocaine abuse/dependence; 2) find most effective dose range for each medication. In this study, amantadine is tested."

Prepulse Inhibition of Startle in Cocaine Dependence - 7

The purpose of this study is to assess the effects of chronic cocaine use on the acoustic startle response and on gating of this response in humans.


Modeling Impaired Judgement in Cocaine Abusers - 6

The purpose of this study is for the modeling of impaired judgement in cocaine abusers.

Effectiveness of Amantadine Hydrochloride for Treatment of Severe Traumatic Brain Injury (TBI)

This is a controlled trial of amantadine to improve level of function following severe traumatic brain injury. The purpose of this study is: 1. To determine whether amantadine hydrochloride, given in a dose of 200-400 mg, improves functional recovery from the vegetative and minimally conscious states 2. To determine whether amantadine-related gains in function persist following drug discontinuation 3. To determine the safety profile of amantadine...

IV Cocaine Abuse: A Laboratory Model - 3

The purpose of this study is to evaluate the effects of buprenorpine on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving in non-opiate dependent cocaine users.

IV Cocaine Abuse: A Laboratory Model - 4

The purpose of this study is to evaluate the effects of pergolide on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving in non-opiate dependent cocaine users.

Development of Human Laboratory Study Model of Cocaine Relapse Prevention II - 1

To study of classical conditioning mechanisms associated with arousal, craving and cocaine use.

Cocaine Effects in Humans: Physiology and Behavior - 1

The purpose of this study is to compare the effects of buprenorphine or methadone maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving, in opiate-dependent cocaine users.

Topiramate to Reduce Cocaine Dependence

Cocaine addiction is a serious health problem with no available medical treatment for preventing relapse. Topiramate, a medication which lowers dopamine levels, may have the ability to diminish cocaine cravings in addicts. The purpose of this study is to determine the effectiveness of topiramate in reducing cocaine's rewarding effects in individuals addicted to cocaine.

IV Cocaine Abuse: A Laboratory Model - 2

The purpose of this study is to evaluate the effects of fluoxetine maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving.

IV Cocaine Abuse: A Laboratory Model - 1

The purpose of this study is to evaluate the effects of desipramine DMI maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving.

Cocaine-Methylphendidate Interaction Study - 4

The purpose of this study is to attempt to identify possible dangerous interactions between cocaine and methylphenidate (MPD). Additional objectives are to determine: a) if MPD reduces the craving and high for cocaine; b) if there are pharmacokinetic and pharmacodynamic interactions between cocaine and MPD; and c) the relationship between cocaine and benzoylecgonine (BE) levels in plasma and BE levels in urine.

Interaction of Stress and Progesterone Levels on Cocaine Cue Induced Craving in Cocaine Dependent Individuals

Stress and cues reminiscent of cocaine use promote craving and relapse in cocaine dependent individuals. In addition, there appears to be gender differences in determinants of relapse to drug use following abstinence in cocaine-dependent individuals. Therefore the purpose of the present study is to study the role of hormonal status on the response to cocaine-related cues with or without stress in cocaine-dependent women and men.

Human Dopamine Transported Imaging in Cocaine Abuse: 2 - 2

The purpose of this study is to determine the density of DA transporters during prolonged cocaine abuse and during withdrawal from cocaine use. This aim will test the hypothesis that DA transporters are altered by cocaine abuse and reestablished during withdrawal.

Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1

The purpose of this study is to determine the density of DA transporters during prolonged cocaine abuse and during withdrawal from cocaine use. This aim will test the hypothesis that DA transporters are altered by cocaine abuse and reestablished during withdrawal.

Disulfiram for Treating Cocaine Dependence in Individuals Maintained on Methadone

Cocaine is an extremely addictive stimulant drug that directly affects the brain. It is used in several different forms and can be snorted, smoked, or injected to achieve the desired effect. Cocaine users are at risk for many health problems, both directly and indirectly related to the effects of cocaine. Disulfiram, a drug used to treat chronic alcoholism, may be effective in reducing cocaine use. This study will evaluate the effectiveness of three different doses of disulfira...

Pharmacological Modulation of Cocaine Effects - 1

The purpose of this study is to conduct human laboratory studies of possible cocaine interactions with various potential treatment medications.

High Dose Nimodipine Treatment Adjunct - 1

The purpose of this study is to determine if nimodipine is more effective than placebo in reducing stimulated craving for cocaine in cocaine dependent individuals denied access to cocaine in inpatient unit.

Psychostimulant Abuse - Novel Treatment Approaches - 1

To determine if acute assessments of profasi and factrel affect plasma cocaine levels and cocaine-induced behavioral changes in men.

Stress and Medication Effects on Cocaine Cue Reactivity

Stressful situations and cues associated with cocaine can lead to craving in cocaine dependent individuals. The purpose of this study is to determine whether guanfacine or modafinil are effective in reducing stress and cue induced craving in cocaine dependent individuals.

Early Phase II Trials for Cocaine Medication Development - 1

The purpose of this study is to develop models for early Phase II testing of potential medications for cocaine dependence: amoxapine, risperidone and other agents. The study was a controlled pilot trial of risperidone in opiate-dependent patients on methadone maintenance. The study explored whether risperidone reduced cocaine use, cocaine craving, and cocaine subjective effects in patients on methadone maintenance who abused cocaine and whether it had an acceptable side effec...

Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1

The purpose of this study is to assess Potential Interactions Between iv Cocaine and RPR 102681

Quetiapine for Cocaine Use and Cravings

The purpose of this study was to collect pilot data on whether quetiapine may be effective in the reduction of cocaine use and cravings in cocaine dependent individuals.

Effectiveness of TA-CD Vaccine in Treating Cocaine Dependent Individuals

Cocaine dependence is a major public health problem; an effective treatment for cocaine dependent individuals has yet to be found. The purpose of this study is to evaluate the effectiveness of the cocaine vaccine candidate TA-CD in treating cocaine dependent individuals.


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