Clinical Trials About "Assessment toxicity application risk C4F7N alternative" RSS

04:22 EDT 19th May 2019 | BioPortfolio

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Showing "Assessment toxicity application risk C4F7N alternative" Clinical Trials 1–25 of 28,000+


HotShOT: Home Safety Occupational Therapy

The purpose of this research study is to examine home safety and fall risk for patients who have undergone hip replacement surgery. The investigators want to know whether evaluating home safety impacts perceived and real risk of falls at home. The study will utilize a fall risk assessment which is a questionnaire that focuses on perceived and real risk of falls at home, as well as a home safety assessment application, the Home for Life App. The participant will be asked about t...

An Oral Dose-Ranging Finding Study in Patients With HIV Disease, CDC Classification Groups IIB, III, and IV-C2

To establish the relationship between the oral dose of zidovudine (AZT) and its hematologic toxicity. AZT has preliminarily been shown to decrease significant events and death in a group of AIDS / Pneumocystis carinii pneumonia (PCP) and AIDS related complex (ARC) patients followed at this time for a limited period. If these data withstand further follow-up, it appears that AZT is a potential antiretroviral agent that may have application in the use of all stages of HIV disease...

Using HIV Risk Assessment Tool to Promote HIV Testing Among Men Who Have Sex With Men

The objective of the study is to evaluate the effectiveness of a HIV risk assessment tool to promote HIV testing and to reduce high risk sexual behaviors among men who have sex with men (MSM). It hypothesizes that the social media-based HIV risk assessment tool can increase 20% HIV testing proportion during the six months follow-up period.

Software for Alternative Communication

The aim of this study is evaluate a software developed for alternative communication designed for people with speech difficulties. The software was executed by 30 volunteers using mobile devices that helped to play the scenarios simulated of communication situations.

Feasibility and Utilization of an Application-based Question Prompt List

The overall goal of this research is to reduce financial toxicity related to the cost of cancer treatment in a diverse patient population. The research tests the feasibility of an application-based ("app") communication intervention designed to improve the frequency and quality of patient-oncologist treatment cost discussions during clinical interactions, which, in turn, should improve other short- and longer-term patient outcomes, including referrals to economic support (e.g.,...

The Alternative Position for the SedLine® Sensor

SedLine® Brain Function Monitoring provides real-time insight into a patient's depth of anesthesia with bilateral data acquisition and processing of electroencephalogram (EEG) signals. Four active EEG leads collect data from the frontal lobe with a sensor position on the patient's forehead. Whenever a frontal approach for neurosurgical procedures is required or the frontal placement of the EEG is not indicated, it would not be possible to place the SedLine® . Numerous...

Treatment Protocol of Voraxaze for Patients Experiencing or at Risk of Methotrexate Toxicity

This protocol evaluates adjunctive treatment of patients receiving high-dose methotrexate (HDMTX; > or = to 1 g/m2) who are experiencing or at risk of MTX toxicity. Patients are considered at risk of MTX toxicity if they have impaired renal function, which can lead to a delay in MTX elimination, or have evidence of delayed elimination based on MTX levels.

Feasibility Study of Monitoring by Web-application on Cytopenia Related to Chemotherapy

Patients should receive a chemotherapy regimen with an overall risk of febrile neutropenia ≥ 20%. The use of the web-application their will be proposed . They will be informed of the risk of neutropenia, fever and bleeding which may occur beyond the fifth day of each chemotherapy cycle (to eliminate fevers related to treatment). The temperature measurement is performed at home by an infrared forehead thermometer provided as part of the study, in a systematic manner once dai...

Geriatric Assessment in Predicting Chemotherapy Toxicity and Vulnerabilities in Older Patients With Cancer

This randomized clinical trial studies a geriatric assessment intervention in predicting chemotherapy toxicity and vulnerabilities (or weakness) in older patients with cancer. Assessing patients' functional status, comorbidities, psychological state, social support, nutritional status, and cognitive function before treatment may help identify vulnerabilities, improve care, and decrease chemotherapy side effects in older patients with cancer.

Alternative Risk Markers in Coronary Artery Disease (ARMCAD)

Estimating the risk of future cardiovascular events such as death, stroke and myocardial infarction using traditional risk factors (such as age, gender, smoking, diabetes, hyperlipidaemia and hypertension) is well accepted in patients with and without existing cardiovascular disease. These estimates are based on a number of robust observational studies, including the original Framingham study. While these methods apply reasonably well on a population level their application t...

Radiation Oncology Mobile Application

To develop a novel a mobile phone application (available on Android and IOS) for patients receiving radiation treatment for head and neck cancer. Through this application, patients will get access to their treatment calender, through a system connected with Mosiac database, which provides a timely and precise access to their treatments schedule. In addition, patients will be able to report their treatment related toxicity in real time fashion, these symptoms will be addressed ...

A Prospective Study for the Assessment of Recurrence Risk in Stage II Colon Cancer Patients Using ColoPrint

This prospective study will address the feasibility and quality assurance of the prognostic profile ColoPrint in clinical practice. ColoPrint risk assessment results will be compared to the risk assessment resulting from various clinical parameters following local protocol/ ASCO criteria and independent investigator risk assessment.

Towards Reducing Resistance and Hematological Toxicity of Linezolid

The study will evaluate and improve the performance of pharmaco-statistical models previously developed in the compassionate use program in patients being treated with linezolid under clinical usage conditions. This study will also develop a sensitive and specific tool that may be used to predict patients at risk of hematological toxicity, based on factors including linezolid concentration and duration of therapy and use these models to better understand the determinants of tox...

Clinical Phase II Clinical Study Evaluating the Toxicity and Efficacy of mFOLFIRINOX Associated With SBRT (Stereotactic Radiotherapy) in Patients With Unresectable Locally Advanced Pancreatic Cancer

Primary goal: Improvement of the therapeutic index by reducing the toxicity of treatment and increasing local control of the cancer process while evaluating the possibility of conversion to the surgical status. Secondary targets: - Survival rate (OS) assessment in patients treated with mFOLFIRINOX + SBRT - Assessment of quality of life using questionnaires: EQ-5D, EORTC (QLQ-C30) and pancreatic cancer-specific QLQ PAS module 26 - Early toxic...

Ecological Momentary Mental Assessment

Suicide is a major health problem that causes annually a million death worldwide. Suicide and suicide attempts are preventable. A history of self-injuries or suicidal attempts are known to be the most important risk factor for death by suicide. Suicidal ideation is also strongly correlated with suicide attempts. The development of Smartphones applications offers new possibilities for data collection and transmission. Moreover, the online help function, when a sui...

Needs Assessment of Cancer Patients With Complementary and Alternative Medicines

The chronic cancer status, multidisciplinary and ambulatory care, as well as the cumbersome effects of the disease and treatments, lead patients to consider other options than those offered by traditional medicine, such as alternative medicine and complementary (CAM)

Biomimetic Remineralization Using Self-Assembling Peptide P11-4 in the Prevention and Treatment of Early Carious Lesions in Primary Anterior Teeth

This study is a single blinded randomized controlled clinical trial on primary anterior teeth of 3-5 year-old patients suffering from 1 or more white spot lesions Class V (ICDAS system II scores 1-2). 48 teeth will be divided into two groups where Group 1 (24 teeth) will receive Self-Assembling Peptide P11-4 at Day 0 and 12 of these will get a re-application at Day 90. Group 2 (24 teeth) will receive Topical Fluoride Varnish Application (Duraphat) at Day 0 and 12 of these will...

Use of a Smartphone© Application to Study Autism Spectrum Disorders (ASD)

This is a prospective, longitudinal, exploratory, open study with a 6-month follow-up period to explore via a specific Smartphone© application the evolution of a child's behavior over 6 months and the (psychological and social) effects of these changes on the family.

Benchmarking the iOS Balance Application Against the Berg Balance Test

This study aims to benchmark the performance of an iOS application against the Berg Balance Scale (BBS), which is the most commonly used assessment tool by clinicians for measuring balance across the continuum from acute care to community-based care. An iPhone will be tied around the waist of the participant and concurrent measurements will be taken for five of the fourteen stances which comprise the BBS.

Prognostic and Predictive Impact of Circulating Tumor DNA in Gastric Cancer Treatment

The evaluation of the chemotherapy efficacy for gastric cancer patients is usually evaluated by computer tomography scans with RECIST criteria that are performed every two months during the treatment. The management of treatment for gastric cancer needs the development of early biomarkers to evaluate the efficacy in order to avoid unnecessary toxicity in case of early chemotherapy resistance. In this prospective study, we will compare the monitoring of circulating tumor DNA wit...

Validation of a Preoperative Cognitive Assessment Tool to Predict the Risk for Postoperative Delirium

This observational cohort study is designed to validate the BrainCheckpreop application as a risk prediction tool for postoperative delirium in patients undergoing cardiac surgery.

Pilot Study of Alternative Treatments of Unexplained Chronic Fatigue

The investigators' long-term goal is to identify, and then provide general practitioners with evidence-based recommendations for therapeutic interventions for unexplained chronic fatigue (UCF). The investigators' central hypothesis guiding this application is that some complimentary and alternative medicine (CAM) practitioners have developed management approaches that are more helpful to patients with UCF than usual care.

Critical Treatment of Coronary Artery Disease

Identifying the critical lesion of coronary artery disease and determining the interventional plan are significant for reducing adverse cardiovascular adverse events. The assessment of critical lesion requires the consideration of plaque morphology, tissue composition, and endometrial stress which leading to rupture. In summary, accurate assessment of critical lesions has high application value. In this study, patients with critical coronary artery disease were divided into two...

A Web Application for Improving Communication on Hemodialysis Rounds

To evaluate a web application tool that hemodialysis patients can use outside of dialysis time to log and prioritize their concerns for the nephrologists. Specifically, the investigators will compare the usability of a web application tool to a structured paper form. The investigators will also use data from semi-structured interviews to better understand the experience and acceptability of the web app among patient participants randomized to the web application and among parti...

Assessment of Limb Perfusion During Junctional Tourniquet

The goal of this study is to use contrast enhanced ultrasound to determine the degree to which flow is reduced during application of a junctional tourniquet (JT). Contrast enhanced ultrasound is performed to quantify thigh and calf perfusion at baseline and during application of the JT

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