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Clinical Trials About "Omnidirectional Deep Brain Stimulation Directional Deep Brain Stimulation" RSS

02:48 EST 15th November 2019 | BioPortfolio

We list hundreds of Clinical Trials about "Omnidirectional Deep Brain Stimulation Directional Deep Brain Stimulation" on BioPortfolio. We draw our references from global clinical trials data listed on ClinicalTrials.gov and refresh our database daily.

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We have published hundreds of Omnidirectional Deep Brain Stimulation Directional Deep Brain Stimulation news stories on BioPortfolio along with dozens of Omnidirectional Deep Brain Stimulation Directional Deep Brain Stimulation Clinical Trials and PubMed Articles about Omnidirectional Deep Brain Stimulation Directional Deep Brain Stimulation for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Omnidirectional Deep Brain Stimulation Directional Deep Brain Stimulation Companies in our database. You can also find out about relevant Omnidirectional Deep Brain Stimulation Directional Deep Brain Stimulation Drugs and Medications on this site too.

Showing "Omnidirectional Deep Brain Stimulation Directional Deep Brain Stimulation" Clinical Trials 1–25 of 12,000+

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Subthalamic Steering for Therapy Optimization in Parkinson's Disease

Twenty patients with idiopathic Parkinson's disease (PD) will be included into this single center randomized controlled double-blind clinical trial (RCT) in a cross-over design. The treatment consists of two different stimulation settings using (i) conventional omnidirectional stimulation of the subthalamic nucleus [STN_O] as active comparator and (ii) directional steering of STN stimulation via a segmented electrode contact [STN_D].


Evaluation of Directional Recording and Stimulation Using spiderSTN

The purpose of this study is to provide proof-of-concept that directional stimulation and directional recording, in an intraoperative setting, is perceivable in a subject. The tests will be performed using a dedicated intraoperative lead connected to an external neuro-recorder/stimulator, during a deep brain stimulation implantation surgery.

Expanding the Therapeutic Window of Deep Brain Stimulation in Parkinson's Disease by Means of Directional Leads

Exploring directional lead


Deep Brain Stimulation for the Treatment of Traumatic Brain Injury

This study involves the treatment of cognitive impairment secondary to moderate to severe brain injury using central thalamic deep brain stimulation. Although all patients will receive stimulation continuously through an implanted pacemaker-like device, half of the patients will have the device deactivated during a blinded assessment phase. The device will be reactivated following this assessment and patients will have the option to continue stimulation in an open-label continu...

Clinical Outcomes for Deep Brain Stimulation

The object of this study is to longitudinally collect clinical outcomes of patients receiving deep brain stimulation for movement disorders with the objective of making retrospective comparisons and tracking of risks, benefits, and complications.

Deep Brain Stimulation in Treating Patients With Dystonia

RATIONALE: Dystonia is a disorder in which the muscles that control voluntary movements are persistently or intermittently contracted (not relaxed). Deep brain stimulation is provided by a small, battery operated implant placed under the skin of the chest that delivers low voltage electrical pulses through a wire under the skin that is connected to a specific area of the brain. Deep brain stimulation may help lessen the symptoms of dystonia. PURPOSE: Phase II/III trial to stud...

Effects of Deep Brain Stimulation of the Dentate Nucleus on Cerebellar Ataxia

Cerebellar ataxias are a group of disorders caused by cerebellar affections, for which currently no specific treatment is available. Some limited studies verified the effects of cerebellar transcranial magnetic stimulation (TMS) on ataxic symptoms, with good results. The hypothesis is that cerebellar TMS could improve ataxic symptoms in some patients and in these patients, chronic cerebellar stimulation through deep brain stimulation could be a therapeutic option. The rationale...

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

The primary objective of this study is to characterize real-world clinical outcomes of Deep Brain Stimulation (DBS) using retrospective review of de-identified patient records.

Deep Brain Stimulation in Patients With Dystonia

The purpose of this study is to evaluate the safety and effectiveness of deep brain stimulation (DBS) of the subthalamic nucleus (STN)for dystonia.

Analgesic Effects of Expectation and Deep Brain Stimulation in Patients With Parkinson's Disease

The study investigates analgesic effects of expectations and deep brain stimulation on chronic and evoked pain in patients with Parkinson's disease. The study includes patients with Parkinson's disease that are exposed to pain stimuli through injection of hypertonic saline. During pain induction and chronic pain evaluation deep brain stimulation treatment is regulated. Pain stimuli and regulation of deep brain stimulation are accompanied by verbal suggestions as to the analges...

Deep Brain Stimulation for Treatment of Severe Alzheimer's Disease

To investigate the safety of deep brain stimulation in the treatment of severe Alzheimer's disease (AD); to investigate the effectiveness of deep brain stimulation in the treatment of severe AD, i.e., effects of deep brain stimulation on cognitive function in patients with severe AD and dementia grading; to investigate the effects of deep brain stimulation on cerebral glucose metabolism in patients with severe AD.

Effect of Deep Brain Stimulation on Depression and Quality of Life in Parkinson’s Patients

We will evaluate the effect of deep brain stimulation on the depression and quality of life in Parkinson’s disease. We aim to compare depression pre-operatively and post-operatively in Parkinson’s patients with deep brain stimulation to Parkinson’s patients evaluated and approved for deep brain stimulation but who did not complete surgery. We will also compare quality of life measures between patients with and without deep brain stimulation.

Invasive Approach to Model Human Cortex-Basal Ganglia Action-Regulating Networks

The brain networks controlling movement are complex, involving multiple areas of the brain. Some neurological diseases, like Parkinson's disease, cause abnormalities in the brain networks. Deep brain stimulation is a treatment that is used to treat these types of neurological diseases. Through this research, the investigators will take advantage of the unique opportunity provided by awake deep brain stimulation surgery to learn more about how the brain functions in a diseased s...

Effect of Deep Brain Stimulation on Lower Urinary Tract Function

The precise mechanisms underlying cerebral regulation of lower urinary tract (LUT) function are still poorly understood. Patients with deep brain stimulation (DBS) offer the unique opportunity to investigate the role of different cerebral centers on LUT function. We hypothesize that DBS has a significant effect on LUT function and that these effects depend on the specific stimulated cerebral center.

Study to Characterize Acute and Chronic Directional Aspects of Deep Brain Stimulation

The primary objective is to characterize the programming effects of Boston Scientific Vercise™ PC System using the DBS Directional Lead for bilateral STN DBS for the treatment of Parkinson's disease in acute and chronic settings.

Deep Brain Stimulation in HUCH Region Between 2006 and 2014

This study reviews the outcome of deep brain stimulation treated patients in Helsinki and Uusimaa University Hospital between 2006 and 2014. The aim of the study is to investigate the outcome and possible side effects of deep brain stimulation treatment.

Flexible vs. Standard Deep Brain Stimulation Programming in Parkinson Disease Patients

Exploring the benefits of the linear lead in deep brain stimulation.

Effects of Deep Brain Stimulation in Parkinson's Disease

The purpose of this study is to identify factors predicting good results in patients treated with deep brain stimulation for Parkinson's disease. The study includes a comparison of two surgical methods used to provide this therapy.

Deep Brain Stimulation for Parkinson's Disease Trial

The purpose of this trial is to evaluate the effect of deep brain stimulation in the the globus pallidus (Gpi) and the subthalamic nucleus (STN) on motor, neuropsychological and psychiatric function, and quality of life in patients with Parkinson's disease.

Effect of Deep Brain Stimulation on Gastrointestinal (GI) Motility

Parkinson's disease is characterized by extra-pyramidal symptoms as well as digestive involvement with gastrointestinal motility (GI) impairment. Deep brain stimulation has been recently developed as a successful treatment for extrapyramidal symptoms. In addition, preliminary reports suggest that this therapy might be successful to relieve GI symptoms as well. The aim of this study is therefore to assess the effect of deep brain stimulation on GI voluntary as well as involuntar...

Deep Brain Stimulation for Morbid Obesity

This is an open-label, phase I pilot trial designed to evaluate the safety and feasibility of deep brain stimulation (DBS) for the treatment of refractory morbid obesity. Patients with diagnoses of morbid obesity will be recruited and enrolled. All patients will receive DBS targeting two brains areas involved in the pathophysiology of obesity and will be followed post-operatively for 12 months.

Deep Brain Stimulation (DBS) for Depression Using Directional Current Steering and Individualized Network Targeting

The goal of the study is to address the unmet need of TRD patients by identifying brain networks critical for treating depression and to use next generation precision DBS with steering capability to engage these targeted networks. The study's goal will be achieved through 3 specific aims: 1. Demonstrate device capability to selectively and predictably engage distinct brain networks 2. Delineate depression-relevant networks and demonstrate behavioral changes wit...

Deep Brain Stimulation (DBS) for Depression Using Directional Current Steering and Individualized Network Targeting

The goal of the study is to address the unmet need of TRD patients by identifying brain networks critical for treating depression and to use next generation precision DBS with steering capability to engage these targeted networks. The study's goal will be achieved through 3 specific aims: Demonstrate device capability to selectively and predictably engage distinct brain networks Delineate depression-relevant networks and demonstrate behavioral changes with network-target...

Deep Brain Stimulation for Treatment-Refractory Major Depression

This study will investigate the use of deep brain stimulation (DBS) to reduce symptom severity and enhance the quality of life for patients with treatment-refractory major depression.

Registry of Deep Brain Stimulation With the VERCISE™ System for Treatment of Dystonia: Vercise DBS Dystonia Registry

To compile characteristics of real-world outcomes of Boston Scientific Corporation's commercially approved VerciseTM Deep Brain Stimulation (DBS) Systems for the treatment of dystonia.


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