Clinical Trials About "Radiotherapy localized sebaceous carcinoma eyelid retrospective analysis patients" RSS

15:30 EST 21st January 2020 | BioPortfolio

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Showing "Radiotherapy localized sebaceous carcinoma eyelid retrospective analysis patients" Clinical Trials 1–25 of 18,000+

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Sentinel Lymph Node (SLN) Biopsy for Sebaceous Gland Carcinoma of Eyelid

Primary Objectives: 1. Identify the rate of SLN (sentinel lymph node) positivity for eyelid sebaceous gland carcinomas. 2. Identify the false negative events associated with SLN biopsy for sebaceous gland carcinomas. Secondary Objective: Record any side effects associated with SLN biopsy for sebaceous gland carcinoma of the eyelid.

Study of Sentinel Lymph Node Biopsy for Conjunctival Melanoma and Sebaceous Cell Carcinoma of the Eyelid

The goal of this clinical research study is to localize the sentinel lymph node (SLN) (s) and biopsy it (them) to see if the patient has small or low volume metastatic disease that would otherwise have been missed. Primary Objectives: - Identify the rate of sentinel lymph node (SLN) positivity in conjunctival/eyelid melanomas - Determine the false negative rate for SLN biopsy for the same Secondary Objective: - Determine the complication rat...


The Effect of Eyelid Margin Debridement on Contact Lens Discomfort

In this study, clinical variables related to eyelids that potentially have an effect on contact lens discomfort will be investigated such as eyelid signs and secretions, eyelid sensitivity, eyelid microbiome, Demodex infestation and tear film properties. The main aim of this study is to understand the duration of efficacy of debridement of the eyelid margin and its impact on various eyelid signs (such as lid wiper epitheliopathy, lid-parallel conjunctival folds, eyelid sensitiv...

Comfort Comparison of Intravitreal Injection Eyelid Retraction Techniques

This study evaluated the discomfort associated with eyelid retraction during intravitreal injections. Participants had eyelid retraction with one of three methods: eyelid speculum, unimanual eyelid retraction method or with a cotton tipped applicator eyelid retraction technique. All participants were given a pain survey immediately after the injection to evaluate their discomfort level.

Subbrow Blepharoplasty Combined With Double Eyelid Surgery for Upper Eyelid Rejuvenation in Asian Women

Subbrow blepharoplasty combined with double eyelid surgery excising the subbrow skin and the supratarsal upper eyelid skin, lifting and fixing the OOM flap, meanwhile restoring the natural and symmetrical appearance, is a safe, effective, and durable way for treating patients presenting with dermatochalasis.

Analysis of Expression of Specific Markers in Hepatocellular Carcinoma

Hepatocellular carcinoma is an aggressive disease with limited therapeutic options. Therefore, new approaches to treat this type of cancer are needed with immunotherapy potentially being one of these. As a first step in the development of novel therapies, expression analysis of specific markers, including tumor antigens will be carried out. This will be done retrospectively using available hepatocellular carcinoma tissue samples.

Physiological Upper Eyelid Laxity

This is a prospective, single-center study in normal subjects aged 20 to 89 years. The objective was to describe upper eyelid laxity by age group (20/29 years old, 30/39 years old, 40/49 years old, 50/59 years old, 60/69 years old, 70/79 years old and 80/89 years old) measured with the method of McNab and studying it according to her customary side of sleep. In addition, we evaluated a method for measuring tarsal laxity.

Study of XOPH5 Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon)

This study will test whether XOPH5 ointment, applied once daily to the lower eyelids for 10 weeks, reduces the prominence of lower eyelid fat in adults with moderate to severe steatoblepharon (excess eyelid fat).

De Novo Lipogenesis of Sebaceous Glands in Acne

There are two purposes of this study: 1. First, the investigators want to see what the differences are in de novo sebaceous lipid production of people with and without acne. 2. Secondly, the investigators want to know what happens to sebaceous gland de novo lipid production before and after treatment with topical tretinoin and oral isotretinoin.

Eyelid Position Interdependence in Involutional Ptosis Patients Submitted to 10% Phenylephrine

The primary aim of this study is to quantify eyelid position changes in tested and opposite eyes in ptosis patients submitted to 1, 2 or 4 drops of 10% phenylephrine in one eye. The secondary objective is to correlate the eye dominance, severity and laterality of ptosis with eyelid position changes in these 3 groups.

A Phase II Trial of Induction Chemotherapy With ND-420, Cisplatin and Fluorouracil Followed by Surgery in the Treatment of Patients With Localized Squamous Cell Carcinoma of the Esophagus

Investigator will assign 53 patients who had been histologically proven localized squamous cell carcinoma of esophagus to receive the induction chemotherapy regimen of ND-420 50 mg/m2 on day 1, cisplatin 70 mg/m2 on day1, plus fluorouracil 700 mg/m2 daily, day1 to day4, every 3 weeks for 2 cycles and then followed by surgical resection. The successful rate of complete treatment per protocol and complete resection will be the primary variant to evaluate in our study.

The Effect of Lumify™ Eyedrops on Eyelid Position

This research study designed to test if Lumify™ eyedrops temporarily raise the upper eyelid. Lumify™ is an FDA approved medication for reducing eye redness. A similar, but stronger product is also used to treat glaucoma. Whether or not it affects the position of the eyelids has not been studied, but we believe that it will raise the position of the upper eyelid, making the eye appear more open.

Studying DNA in Tumor Tissue Samples From Patients With Localized or Metastatic Osteosarcoma

RATIONALE: Studying samples of tumor tissue and blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at DNA in tumor tissue samples from patients with localized or metastatic osteosarcoma.

Clinicopathological Importance of Colorectal Medullary Carcinoma: Retrospective Cohort Study

Medullary carcinoma (MC) is a rare tumor with solid growth pattern without glandular differentiation and constitute less than 1% of colorectal cancer. Lymph node positivity and distant organ metastasis were reported to be lower than other poorly differentiated adenocarcinomas. Therefore, the diagnosis of MC is pathologically important in terms of follow-up and treatment. MC is commonly localized in the right colon, has a large tumor size, and is mostly diagnosed in the T4 stage...

Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface Surgeries

The aim of the study: Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface Surgeries. Study design: an interventional study that will be conducted at the ophthalmology department, Meir hospital, Kfar Saba, Israel. the study will include 60 healthy patients, at the ages of 40-80, which are candidates for eyelid surgery: blepharoptosis repair, blepharoplasty, ectropion repair and entropion repair. The patients will be recruited fro...

Clinical Safety Study on an Eyelid Warming Device to Evaluate the Eyelid and Cornea Temperature in Healthy Volunteers

The eyelid warming device is designed to relieve the symptoms of dysfunction of the glands in the eyelids. Prospective, non comparative, open, monocentre study. The objectives are: - To verify and establish the temperature of the eyelids and cornea for each eye before and after 10 minutes device application - To evaluate the ocular surface, NIBUT and IOP before and after device application - To determine the acceptability of healthy volunteers on ...

Nano-Pulse Stimulation (NPS) in Sebaceous Hyperplasia

This prospective, open label, muti-center study evaluates the use of Nano-Pulse Stimulation (NPS) in the treatment of Sebaceous Hyperplasia (SH) lesions less than 2.5mm in size.

Comfort Associated With The Use Of Eyelid Cleansing Products Available For The Management Of Demodex Folliculorum

This aim of this study to quantify the subjective ocular awareness of different eyelid cleansing wipes available for the management of Demodex folliculorum.

Use Of Oral Itraconazole In Patients With Locally Limited Basocellular Carcinoma Of Skin.

Patients with localized basocellular carcinoma of the skin, will receive oral Itraconazole, 200 mg twice daily, for 60 days, prior to curative intent surgery.

Localized Radiation Therapy or Recombinant Interferon Beta and MSB0010718C With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma

This phase I/II trial studies the side effects and how well localized radiation therapy or recombinant interferon beta and anti-programmed death-ligand 1 (PD-L1) monoclonal antibody MSB0010718C (MSB0010718C) with or without cellular adoptive immunotherapy works in treating patients with Merkel cell carcinoma that has spread to other parts of the body. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Interferon beta is a substance that can improve...

Shock Waves for Treatment of Gynoid Lipodystrophy and Localized Fat

PURPOSE: To evaluate the efficacy of shock waves extracorporea in improving body contour,decrease fat localized and appearance of gynoid lipodystrophy. SUBJECTS AND METHODS: A prospective and comparative longitudinal clinical study will be performed in 30 women with localized fat and gynoid lipodystrophy. Patients will be submitted data collection and assessments and before and after treatment. HYPOTHESES: It is expected that the patients will present improvement in the body ...

A Retrospective Multicenter Analysis of PD-L1 Expression in Japanese Renal Cell Carcinoma Patients

This is a multicenter retrospective study designed to compare overall survival (OS) by PD-L1 expression status in patients with RCC who have received systemic chemotherapy for recurrent or metastatic RCC, to determine whether the prognosis is worse in PD-L1-positive than in PD-L1-negative RCC. Total 600 RCC surgical specimens will be collected from patients who started systemic chemotherapy for recurrent or metastatic RCC between January 1, 2010 and December 31, 2015 at ...

Non-surgical Correction of Eyelid Paralysis With External Magnet Systems

Objective 1: Determine the safety and feasibility of externally mounted magnets for extended management of chronic eyelid movement disorders by measuring visual acuity and corneal and skin integrity and comfort over 8 weeks of wear. Objective 2: Collect preliminary data on the relative efficacy of external magnetic devices by comparing them to externally mounted lid weights and ptosis crutches using rating scales and video analysis of blink biomechanics.

Autoantibody Blood Test in Finding Metastasis in Patients With Localized or Metastatic Kidney Cancer

RATIONALE: Studying specific autoantibodies in blood samples from patients with cancer may help doctors find metastasis and help plan cancer treatment. PURPOSE: This clinical trial is studying an autoantibody blood test in finding metastasis in patients with localized or metastatic kidney cancer.

BreAst Cancer and Cardiotoxicity Induced by RAdioTherapy: the BACCARAT Study

Breast radiotherapy RT used until the 1990s was clearly responsible for increased mortality due to long term cardiac complications. Since the 2000s, improvements have appeared in dose distributions to organ at risks such as heart, but now, little is known on the risk of potential cardiac impairment in this population, in particular for chemotherapy naive patients. Based on the state that clinically detectable cardiotoxicity is generally preceded by subclinical cardiac dysfuncti...

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