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10:06 EST 23rd November 2017 | BioPortfolio

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Elsevier launches solution to accelerate drug discovery through comprehensive prediction and assessment of drug-drug interactions

New PharmaPendium solution comes with DDI risk calculator enabling earlier and more complete risk mitigation strategies for potential drug-drug interactions

At $475,000, new cancer drug raises thorny questions about drug pricing — and value

Pricing for the Novartis drug, which treats an aggressive form of childhood leukemia, has stirred the heated national debate over prescription drug costs.

New Method Yields Shortcut in Drug Development

NewsThe majority of promising new drug candidates are effective only within the body’s cells, but quick general methods of determining intracellular drug quantities are lacking.

Shire Receives Orphan Drug Designation for Gene Therapy Candidate SHP654

NewsOrphan Drug Designation is intended to advance drug development for rare diseases.

France to prosecute its drug regulator and Servier in scandal over diabetes drug

France’s drug regulator and one of its leading drug companies, Servier, will stand trial as legal persons over the marketing of the antidiabetes and weight loss drug benfluorex (marketed in France a...

FDA declines to approve PTC's Duchenne drug

(Reuters) - The U.S. Food and Drug Administration has declined to approve PTC Therapeutics Inc's experimental drug to treat Duchenne muscular dystrophy, saying an additional clinical trial would be ne...

Drug Development at the Portfolio Level

This Viewpoint discusses the drug development portfolio—a family of trials assessing a drug for different indications or in different combinations with other drugs—and summarizes some of the chall...

Concern With Potential Rise in Super Potent Cannabis Concentrates

NewsThe research was based on data from the Global Drug Survey, the world’s largest drug survey that collects data about drug users.

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Preferences of Patients and Pharmacists with Regard to the Management of Drug-Drug Interactions: A Choice-Based Conjoint Analysis.

The management of drug-drug interactions (DDIs) is a complex process in which risk-benefit assessments should be combined with the patient's perspective.

Trends in reports of driving following illicit drug consumption among regular drug users in Australia, 2007-2013: Has random roadside drug testing had a deterrent effect?

Driving following illicit drug consumption ('drug-driving') is a potential road safety risk. Roadside drug testing (RDT) is conducted across Australia with the dual aims of prosecuting drivers with dr...

Drug use generations and patterns of injection drug use: Birth cohort differences among people who inject drugs in Los Angeles and San Francisco, California.

A robust literature documents generational trends in drug use. We examined the implications of changing national drug use patterns on drug injection histories of diverse people who inject drugs (PWID)...

Drug cue reactivity involves hierarchical instrumental learning: evidence from a biconditional Pavlovian to instrumental transfer task.

Drug cue reactivity plays a crucial role in addiction, yet the underlying mechanisms are poorly understood. According to the binary associative account, drug stimuli retrieve an expectation of the dru...

Managing Drug-Drug Interaction Between Ombitasvir, Paritaprevir/Ritonavir, Dasabuvir, and Mycophenolate Mofetil.

No drug-drug interaction study has been conducted to date for the combination of ombitasvir, paritaprevir/ritonavir, dasabuvir (3D), and mycophenolic acid (MPA). We here report the case of a hepatitis...

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