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Search Results for "Melanin Ulk1"

21:06 EST 24th November 2017 | BioPortfolio

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Melanin-linked skin conditions: Breakthrough

Spots resulting from too much sun exposure and other effects of dysfunctional melanin production may become a thing of the past. Scientists have solved the structure of one of the three enzymes that g...

Scalable process discovered to produce structural colors inspired by bird feathers

(University of Akron) Researchers made nano-sized balls of melanin aggregate into clusters called supraballs. Melanin appears black in individual nanoparticles. But altering spacing of the nanoparticl...

New breakthrough opens doors to treat melanin-linked skin conditions

(European Synchrotron Radiation Facility) Spots resulting from too much sun exposure and other effects of dysfunctional melanin production may become a thing of the past. Scientists have solved the st...

Cancer immunotherapy uses melanin against melanoma

(North Carolina State University) Researchers have developed a melanin-enhanced cancer immunotherapy technique that can also serve as a vaccine, based on early experiments done in a mouse model. The t...

Researchers look to improve detection of skin cancer lacking pigment melanin

(UNC Lineberger Comprehensive Cancer Center) UNC Lineberger scientists were part of a multi-institution research team that identifed key features linked to amelanotic melanoma, a form of skin cancer t...

Facial Pores in Melanin Layer and Genetic Algorithms for Human Face Characterization

Facial Pores in Melanin Layer and Genetic Algorithms for Human Face CharacterizationPages 12-21Author Carlos Villegas-QuezadaJoan ClimenAbstract The characterization of a face is a vital element for ...

Study Illuminates Genetics of Skin Color

Researchers identified genes related to melanin levels in African populations.

Researchers Discover How UV Rays Cause Skin Cancer

ArticleUnder normal conditions, UV radiation from the sun activates melanocytes to release melanin.Staff Author: 

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Ulk1 over-expression in human gastric cancer is correlated with patients' T classification and cancer relapse.

Ulk1 is a key autophagy protein. Here, we tested expression and potential function of Ulk1 in human gastric cancer. Ulk1 mRNA and protein were significantly elevated in multiple fresh human gastric ca...

ULK1 ubiquitylation is regulated by phosphorylation on its carboxy terminus.

Autophagy is a highly conserved process that acts sequestering cytoplasmic components for their degradation by the lysosomes. It consists of several sequential steps that have to be finely regulated t...

Autophagy participates in isoliquiritigenin-induced melanin degradation in human epidermal keratinocytes through PI3K/AKT/mTOR signaling.

Melanin is the pigment responsible for the color of human skin and hair. Melanin serves as a double-edge sword which can exert both protective and spot-causing effects on skin. Although melanin has an...

SBI0206965, a novel inhibitor of Ulk1, suppresses non-small cell lung cancer cell growth by modulating both autophagy and apoptosis pathways.

Lung cancer is a major public health problem worldwide. Non-small cell lung cancer (NSCLC) accounts for 85% of lung cancer cases. Autophagy has recently sparked great interest, and it is thought to pa...

Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo.

UNC-51-like kinase 1 (ULK1) is well-known to initiate autophagy, and the downregulation of ULK1 has been found in most breast cancer tissues. Thus, the activation of ULK1-modulated autophagy could be ...

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