Search Results for "Apatinib"

22:40 EDT 18th March 2018 | BioPortfolio

Original Source: Apatinib in Combination With Docetaxel for Patients With Advanced NSCLC

In order to explore a new treatment strategy for patients with failed NSCLC platinum-containing double-drug therapy, this study was to investigate the clinical efficacy of apatinib in combination with docetaxel for patients with advanced NSCLC after failure of platinum-based regime

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LSKB Announces Official Nonproprietary Naming of Apatinib (YN968D1): RIVOCERANIB

LSKB, which owns the global rights to rivoceranib outside of Chinaand is conducting a global Phase 3 clinical study in gastric cancer, will hereafter Read more...

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Apatinib promotes autophagy and apoptosis through VEGFR2/STAT3/BCL-2 signaling in osteosarcoma.

The cure rate of osteosarcoma has not improved in the past 30 years. The search for new treatments and drugs is urgently needed. Apatinib is a high selectivity inhibitor of vascular endothelial growth...

Pharmacokinetic Drug Interactions of Apatinib With Rifampin and Itraconazole.

Apatinib is a small-molecule tyrosine kinase inhibitor that has been approved for the treatment of patients with advanced-stage gastric cancer or gastroesophageal junction cancer who have progressed o...

Novel role of apatinib as a multi-target RTK inhibitor in the direct suppression of hepatocellular carcinoma cells.

Although apatinib has been demonstrated with potential antitumor activity in multiple solid tumors, the underlying mechanism of apatinib for the treatment of hepatocellular carcinoma (HCC) remains unc...

Apatinib Inhibits Angiogenesis Via Suppressing Akt/GSK3β/ANG Signaling Pathway in Anaplastic Thyroid Cancer.

Anaplastic thyroid carcinoma (ATC) is one of the most lethal human malignancies, and there is no efficient method to slow its process. Apatinib, a novel tyrosine kinase inhibitor (TKI), has been confi...

Case report of apatinib mesylate treatment in rare advanced tracheal adenoid cystic carcinoma.

A 57-year-old man was admitted to our department 10 years ago, diagnosed with tracheal adenoid cystic carcinoma. After discontinuing chemotherapy and radiotherapy, the disease recurred in December 2...

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