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02:20 EDT 23rd July 2018 | BioPortfolio

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TICH-2: Tranexamic Acid for ICH Yields Mixed Results

An agent often prescribed to stop bleeding from trauma and postpartum hemorrhage is now being tested in intracerebral hemorrhage. Medscape Medical News

[Articles] Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial

Functional status 90 days after intracerebral haemorrhage did not differ significantly between patients who received tranexamic acid and those who received placebo, despite a reduction in early deaths...

Tranexamic Acid Immediately After Vaginal Delivery Cuts Risk of PPH

(MedPage Today) -- Higher rates of nausea/vomiting, but not severe adverse events

Low cost, easy to administer drug may be the key to preventing maternal deaths

(Society for Maternal-Fetal Medicine) In a multicenter, randomized controlled trial, researchers demonstrated that tranexamic acid can prevent postpartum hemorrhage in certain vaginal deliveries.

Early Antifibrinolytic Therapy Cuts Mortality in Postpartum Hemorrhage

Tranexamic acid (TXA) reduces the risk of death from primary postpartum hemorrhage (PPH), but only when given within three hours of delivery, according to a new Cochrane review. Reuters Health Infor...

Most Bleeding Events in Non-CVD Patients Are GI-Related

WEDNESDAY, June 27, 2018 -- Among a cohort of individuals without cardiovascular disease (CVD) not receiving antiplatelet therapy, most major bleeding events involved gastrointestinal bleeding and 7 p...

'We've Scared Women': The Growth of Prophylactic Mastectomy

Why is it that women with cancer in one breast are increasingly likely to opt for contralateral prophylactic mastectomy, when the evidence shows no survival benefit? Medscape Oncology

The Cost of Contralateral Prophylactic Mastectomy

In this article, the economic value of contralateral prophylactic mastectomy among women with early-stage unilateral breast cancer is explored. Plastic and Reconstructive Surgery

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Supportive topical tranexamic acid application for hemostasis in oral bleeding events - Retrospective cohort study of 542 patients.

Tranexamic acid (TXA) is widely used in the prevention of postsurgical oral bleeding. Tranexamic acid in addition to further surgical measures is widely utilized in prevention of post-surgical oral bl...

Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial.

Tranexamic acid can prevent death due to bleeding after trauma and post-partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma expansion and improves outcome in adults with s...

Left atrial thrombi following tranexamic acid in a bleeding trauma patient-A word of caution.

We describe the case of a bleeding trauma patient who received tranexamic acid (TXA) during air transport who subsequently developed multiple intra-cardiac thrombi. The administration of TXA during tr...

Treatment of melasma using tranexamic acid: what's known and what's next.

Tranexamic acid is a procoagulant agent that is approved by the US Food and Drug Administration for treatment of menorrhagia and to prevent hemorrhage in patients with hemophilia undergoing tooth extr...

Comparison of the efficacy of intravenous tranexamic acid with and without topical administration versus placebo in urgent endoscopy rate for acute gastrointestinal bleeding: A double-blind randomized controlled trial.

Tranexamic acid (TXA), a synthetic antifibrinolytic drug, is effective as a treatment for serious hemorrhage, including bleeding arising from major trauma and post-operative interventions. Significant...

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