Search Results for "Gram Negative Bacteraemia Duration Antibiotics"

04:56 EDT 19th March 2018 | BioPortfolio

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Vancomycin is an antobiotic indicated for the treatment of serious, life-threatening infections by Gram-positive bacteria that are unresponsive to other less-toxic antibiotics. In particular, vancom...

Gram stain


Prophylactic antibiotics

Selection and Use of Antibiotics

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Mutabilis joins European ENABLE project to develop new antibiotics

Mutabilis has been selected by the European Gram-negative antibacterial engine (ENABLE) project to focus on the improved development of antibiotics against infections caused by multi-resistant, Gram-n...

Mixing and Cycling Similarly Effective on Gram-negative Bacteria in ICU

Cycling and mixing, two strategies for rotating antibiotics, do not differ significantly in their impact on the prevalence of antibiotic-resistant gram-negative bacteria in the ICU, new research from ...

[Comment] Evidence to improve the treatment of infections caused by carbapenem-resistant Gram-negative bacteria

WHO recognises carbapenem-resistant Acinetobacter baumannii, Pseudomonas aeruginosa, and Entero-bacteriaceae as pathogens of crucial importance for the development of novel antibiotics.1 These bacteri...

Membrane Vacuum Cleaner Suggested as Potential Gram-negative Bacteria Target

Scientists at the U.K.’s University of Newcastle suggest that a bacterial membrane protein that acts as a type of membrane vacuum cleaner could represent a promising new target for rendering harmful...

Therapy Duration and Follow-up Blood Cultures in Bacteremia

Two recent studies can help streamline therapy of gram-negative bloodstream infections. Society for Healthcare Epidemiology of America (SHEA)

Multidrug-resistant gram-negative bacterial infections in a teaching hospital in Ghana

Multidrug-resistant Gram-negative bacteria have emerged as major clinical and therapeutic dilemma in hospitals in Ghana.

Follow-up Blood Cultures in Gram-negative Bacteremia — Don’t Order Them

In contrast to blood cultures obtained on therapy in patients with Gram-positive bacteremia and endocarditis, follow-up blood cultures in patients with Gram-negative bacteremia seldom provide useful i...

[Articles] Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

Future development strategies should focus on antibiotics that are active against multidrug-resistant tuberculosis and Gram-negative bacteria. The global strategy should include antibiotic-resistant b...

Matching PubMed Articles

Duration of exposure to multiple antibiotics is associated with increased risk of VRE bacteraemia: a nested case-control study.

VRE bacteraemia has a high mortality and continues to defy control. Antibiotic risk factors for VRE bacteraemia have not been adequately defined. We aimed to determine the risk factors for VRE bactera...

Membrane-active macromolecules kill antibiotic-tolerant bacteria and potentiate antibiotics towards Gram-negative bacteria.

Chronic bacterial biofilms place a massive burden on healthcare due to the presence of antibiotic-tolerant dormant bacteria. Some of the conventional antibiotics such as erythromycin, vancomycin, line...

Claramines : A new class of broad-spectrum antimicrobial agents with bimodal activity.

The emergence of multidrug resistant bacteria/pathogens has highlighted the need for the development of new antibiotics. In this manuscript, we report herein our results dealing with the broad spectru...

Compound design guidelines for evading the efflux and permeation barriers of Escherichia coli with the oxazolidinone class of antibacterials: Test case for a general approach to improving whole cell Gram-negative activity.

Previously we reported the results from an effort to improve Gram-negative antibacterial activity in the oxazolidinone class of antibiotics via a systematic medicinal chemistry campaign focused entire...

Bacterial outer membrane constriction.

The outer membrane of Gram-negative bacteria is a crucial permeability barrier allowing the cells to survive a myriad of toxic compounds, including many antibiotics. This innate form of antibiotic res...

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