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Debate exists regarding the safety of metformin and the risk of metformin-associated lactic acidosis, particularly in the setting of kidney dysfunction. Data from two studies examining the interplay b...
The incidence of cardiovascular events decreased among adults with type 2 diabetes who received pioglitazone or a sulfonylurea as an add-on to metformin monotherapy, according to findings from the TOS...
Women who have had diabetes during pregnancy appear to profit the most from metformin treatment to reduce the risk of developing type 2 diabetes, according to the latest findings from the DPP study. ...
Here is evidence that metformin, especially at high doses and for long periods, is associated with increased risk for neurodegenerative diseases and dementia.
New REMOVAL data presented at EASD 2017 reveal effects of metformin on renal function, biomarkers, and more in patients with type 1 diabetes. Medscape Diabetes & Endocrinology
Metformin is widely used in the treatment of type 2 diabetes (T2D), but its mechanism of action is poorly defined. Recent evidence implicates the gut microbiota as a site of metformin action. In a dou...
The efficacy and safety of seven regimens based on metformin (placebo plus metformin, dapagliflozin plus metformin, vildagliptin plus metformin, saxagliptin plus metformin, empagliflozin plus metformi...
Metformin presents better survival rates than other oral antidiabetics in the treatment of type 2 diabetes. However, these benefits may be dampened by inadequate treatment adherence.
Temporal lobe epilepsy (TLE) is a common form of drug-resistant epilepsy that sometimes responds to dietary manipulation such as the 'ketogenic diet'. Here we have investigated the effects of metformi...
Metformin is a commonly used oral antidiabetic agent that has been associated with decreased cancer risk. However, data regarding the association between metformin use and the risk of meningioma are u...