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Debate exists regarding the safety of metformin and the risk of metformin-associated lactic acidosis, particularly in the setting of kidney dysfunction. Data from two studies examining the interplay b...
Using metagenomic techniques, investigators determined that two Gram-negative anaerobes, Prevotella and Porphyromonas, predominate in hidradenitis suppurativa lesions. Two others, Fusobacterium and Pa...
The incidence of cardiovascular events decreased among adults with type 2 diabetes who received pioglitazone or a sulfonylurea as an add-on to metformin monotherapy, according to findings from the TOS...
(HealthDay)—A novel score can assess the severity of hidradenitis suppurativa (HS), according to a study published online June 21 in the British Journal of Dermatology.
Mounting evidence that biofilms are involved in hidradenitis suppurativa suggests that a biofilm-based treatment strategy, such as used in other chronic wound infections, may be effective. The Briti...
Women who have had diabetes during pregnancy appear to profit the most from metformin treatment to reduce the risk of developing type 2 diabetes, according to the latest findings from the DPP study. ...
Ergebnisse der randomisierten Phase-II-Studie zur Beurteilung von MABp1 für die Behandlung von Hidradenitis suppurativa AUSTIN, Texas (USA), 7. Sept. 2017 (GLOBE NEWSWIRE) - XBiotech Inc. (NASDAQ:.....
Here is evidence that metformin, especially at high doses and for long periods, is associated with increased risk for neurodegenerative diseases and dementia.
The Symposium on Hidradenitis Suppurativa Advances (SHSA) took place on 22-23 October 2016 at Women's College Hospital in Toronto, Canada. This symposium was a joint meeting of the Canadian Hidradenit...
Which treatments have been shown to be effective in randomized clinical trials (RCTs) for hidradenitis suppurativa (HS) in adults?
Metformin is widely used in the treatment of type 2 diabetes (T2D), but its mechanism of action is poorly defined. Recent evidence implicates the gut microbiota as a site of metformin action. In a dou...
A 56 year-old man presented to our Hidradenitis Clinic with an exophytic, bovine-red, ulcerated plaque in the left axillae (figure 1). He reported that he was diagnosed with hidradenitis suppurativa w...
The efficacy and safety of seven regimens based on metformin (placebo plus metformin, dapagliflozin plus metformin, vildagliptin plus metformin, saxagliptin plus metformin, empagliflozin plus metformi...