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Selective serotonin reuptake inhibitors SSRIs

17:14 EST 22nd November 2017 | BioPortfolio

Serotonin and norepinephrine reuptake inhibitors (SNRIs) are a class of medications that are effective at easing depression symptoms. SNRIs are also sometimes used to treat other conditions such as anxiety and nerve pain.

How SNRIs work

Serotonin (ser-o-TOE-nin) and norepinephrine (nor-ep-ih-NEF-rin) reuptake inhibitors ease depression by affecting chemical messengers (neurotransmitters) used to communicate between brain cells. Like most antidepressants, SNRIs work by changing the levels of one or more of these naturally occurring brain chemicals.

SNRIs block the absorption (reuptake) of the neurotransmitters serotonin and norepinephrine in the brain. They also affect certain other neurotransmitters. Changing the balance of these chemicals seems to help brain cells send and receive messages, which in turn boosts mood. Medications in this group of antidepressants are sometimes called dual-action antidepressants.

Top U.S. market share of SNRIs  based on revenue 2013

Top U.S. market share of SNRIs based on revenue 2013
Cymbalta 84.0
Pristiq 9.7
Venlafaxine HCl ER 3.6
Effexor XR 1.8
Venlafaxine HCl 0.9


Source IMS Health

Note * SNRI: Serotonin-norepinephrine reuptake inhibitor.

Publication

Published by Drug Store News
Publication date February 2014
Original source Drug Store News, February 2014, page 36
 
For further information:

http://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20044970
 
 
 

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