Smoking Cessation Report, 2009-2024

1 Executive Summary

2 Introduction to Smoking Cessation
2.1 Tobacco
2.1.1 Types of Tobacco Consumption
2.1.2 Tobacco Use is a Global Pandemic
2.2 Nicotine Addiction
2.3 Smoking Cessation
2.3.1 Why is it Difficult to Stop Smoking?
2.3.2 Methods for Smoking Cessation
2.3.3 Pharmacological Smoking Cessation Products
2.4 Nicotine Replacement Therapy (NRT)
2.4.1 Nicorette NRT (Johnson & Johnson/Takeda)
2.4.2 Nicabate/NicoDerm/Nicorette/NiQuitin NRT Brands (GSK)
2.4.3 Novartis NRT Brands
2.4.4 Other NRT Manufacturers
2.5 Bupropion
2.5.1 Zyban (GSK/Biovail)
2.5.2 Generic Bupropion Drugs
2.6 Chantix/Champix (varenicline, Pfizer)
2.7 Off-Label Drug Prescribing for Smoking Cessation

3 The Global Smoking Cessation Market
3.1 The Global Smoking Cessation Market, 2007-2008
3.1.1 Smoking Cessation Market Value, 2007-2008
3.1.2 Leading Smoking Cessation Product Types, 2007-2008
3.1.3 Leading Smoking Cessation Brands, 2007
3.1.4 Leading Manufacturers of Smoking Cessation Products, 2007
3.2 Global Smoking Cessation Market Forecasts, 2009-2024
3.2.1 Growth in the Smoking Cessation Market, 2009-2024
3.2.2 Emerging Markets and the Fate of Chantix: Smoking Cessation Market Forecast, 2009-2014
3.2.3 What are the Prospects for the Smoking Cessation Market during 2014-2019?
3.2.4 During 2019-2024 the Smoking Cessation Market Growth Will Accelerate
3.2.5 Smoking Cessation Product Type Sales Forecast, 2009-2024
3.2.6 Nicotine Replacement Therapies Sales Forecast, 2009-2024
3.2.7 Chantix/Champix Sales Forecast, 2009-2024
3.2.8 Bupropion Smoking Cessation Drugs Sales Forecast, 2009-2024

4 Leading Eight Smoking Cessation Country Markets
4.1 Eight Smoking Cessation Markets Had 74% of 2007 World Sales
4.2 Leading Eight Smoking Cessation Country Markets Forecast, 2009-2024
4.3 The US Smoking Cessation Market
4.3.1 Smoking Prevalence Declining in US
4.3.2 Availability and Reimbursement of Smoking Cessation Aids in the US
4.3.3 US Smoking Cessation Market Revenue, 2007-2008
4.3.4 Leading US Smoking Cessation Product Types, 2007-2008
4.3.5 Is there Scope for US Smoking Cessation Market Expansion?
4.3.6 US Smoking Cessation Market Forecast, 2009-2024
4.3.7 US Nicotine Replacement Therapies Sales Forecast, 2009-2024
4.3.8 Chantix (US) Sales Forecast, 2009-2024
4.4 The Canadian Smoking Cessation Market
4.4.1 Current Smoking Prevalence in Canada
4.4.2 Availability and Reimbursement of Smoking Cessation Products in Canada
4.4.3 Canadian Smoking Cessation Market Revenues and Market Shares, 2007
4.4.4 Factors Affecting the Canadian Smoking Cessation Market
4.4.5 Canadian Smoking Cessation Market Forecast, 2009-2024
4.5 The UK Smoking Cessation Market
4.5.1 Tobacco Use in the UK
4.5.2 The UK Pioneers Smoking Cessation Reimbursement and General Sales OTC Retailing of NRT
4.5.3 The UK is Europe’s Largest Smoking Cessation Market
4.5.4 UK Government Anti-Smoking Legislation Lifts Market
4.5.5 UK Smoking Cessation Market Forecast, 2009-2024
4.6 The French Smoking Cessation Market
4.6.1 French Smoking Prevalence
4.6.2 The French Smoking Cessation Market, 2007-2008
4.6.3 Leading Product Types in the French Smoking Cessation Market, 2007
4.6.4 French Government’s Provision of Smoking Cessation Aid Better than in Many Other European Countries
4.6.5 French Smoking Cessation Market Forecast, 2009-2024
4.7 The Swedish Smoking Cessation Market
4.7.1 Snus in Sweden Increasing in Prevalence
4.7.2 The Swedish Smoking Cessation Market, 2007-2008
4.7.3 Leading Product Types in the Swedish Smoking Cessation Market, 2007
4.7.4 Swedish Smoking Cessation Market Forecast, 2009-2024
4.8 The German Smoking Cessation Market
4.8.1 The German Smoking Cessation Market, 2007-2008
4.8.2 Leading Product Types in the German Smoking Cessation Market, 2007
4.8.3 Factors Holding Back the German Smoking Cessation Market
4.8.4 German Smoking Cessation Market Forecast, 2009-2024
4.9 The Australian Smoking Cessation Market
4.9.1 The Australian Smoking Cessation Market, 2007-2008
4.9.2 Leading Australian Smoking Cessation Product Types, 2007
4.9.3 Australian Smoking Cessation Market Forecast, 2009-2024
4.10 The Japanese Smoking Cessation Market
4.10.1 Japan has an Undeveloped Smoking Cessation Market
4.10.2 The Japanese Smoking Cessation Market, 2007-2008
4.10.3 Japanese Smoking Cessation Market Forecast, 2009-2024

5 BRIC Smoking Cessation Markets
5.1 Greatest Market Growth Predicted in BRIC
5.2 The Brazilian Smoking Cessation Market
5.2.1 Brazilian Smoking Prevalence
5.2.2 The Brazilian Government has Set Smoking Cessation as a Health Priority
5.2.3 The Brazilian Smoking Cessation Market, 2007
5.2.4 Brazilian Smoking Cessation Market Forecast, 2009-2024
5.3 The Russian Smoking Cessation Market
5.3.1 High Smoking Prevalence in Russia
5.3.2 The Russian Smoking Cessation Market, 2007-2008
5.3.3 Russia Signed the Framework Convention on Tobacco Control in 2008
5.3.4 Russian Smoking Cessation Market Forecast, 2009-2024
5.4 The Indian Smoking Cessation Market
5.4.1 Tobacco in India is Both Smoked and Chewed
5.4.2 The Indian Smoking Cessation Market, 2007-2008
5.4.3 Indian Smoking Cessation Market Still in its Infancy
5.4.4 Prospects for Growth of the Indian Smoking Cessation Market
5.4.5 Indian Smoking Cessation Market Forecast, 2009-2024
5.5 The Chinese Smoking Cessation Market
5.5.1 More than 5 Billion Cigarettes are Smoked in China Every Day
5.5.2 The Chinese Smoking Cessation Market, 2007-2008
5.5.3 The Chinese Smoking Cessation Market is Undeveloped
5.5.4 Smoking Cessation Market Prospects in China and Hong Kong
5.5.5 Chinese Smoking Cessation Market Forecast, 2009-2024

6 Issues Affecting the Smoking Cessation Market
6.1 SWOT Analysis for the Smoking Cessation Market
6.2 Strengths of the Smoking Cessation Industry
6.2.1 Innovation in Smoking Cessation Therapies
6.2.2 Innovative Marketing Techniques
6.2.3 Manufacturers are Providing Support Plans in Combination with Pharmacotherapy
6.2.4 OTC-Switching
6.3 Weaknesses of the Smoking Cessation Industry
6.3.1 Drugs Do Not Replace the Tactile and Oral Sensations Obtained from Smoking
6.3.2 Currently-Marketed Smoking Cessation Therapies Have High Relapse Rate
6.4 Opportunities for the Smoking Cessation Market
6.4.1 Smoking is Prevalent Worldwide and Slowly Increasing
6.4.2 Countries with Untapped Smoking Cessation Market Potential
6.4.3 Growth of Emerging-Economy Smoking Cessation Markets
6.4.4 Health Effects of Tobacco
6.4.5 Economic Impact of Tobacco
6.4.6 Framework Convention on Tobacco Control (FCTC)
6.4.7 Government Smoking Cessation Programmes
6.4.8 Increasing Tobacco Taxes
6.4.9 Smoking Bans
6.4.10 Warning Information on Tobacco Products
6.4.11 Bans on Tobacco Advertising, Promotion and Sponsorship
6.5 Threats to the Smoking Cessation Industry
6.5.1 Concern over Side-Effects of Smoking Cessation Drugs
6.5.1.1 Champix/Chantix Showed Potential, but then Hit by Safety Concerns
6.5.1.2 Side-Effect Concerns for NRT and Bupropion
6.5.1.3 The Result of Side-Effect Concerns
6.5.2 Lack of Reimbursement for Smoking Cessation Therapies
6.5.3 Traditional Smokeless Tobacco
6.5.3.1 Snus and Gutkha
6.5.3.2 A Possible Impact of Greater Smokeless Tobacco Prevalence
6.5.4 The E-Cigarette
6.5.4.1 What are E-Cigarettes?
6.5.4.2 The E-Cigarette Market
6.5.4.3 E-Cigarettes Will Revolutionise the Face of Tobacco Smoking and Could Pose a Threat to the Smoking Cessation Market
6.5.4.4 Will E-Cigarettes Compete with Smoking Cessation Therapies?

7 The Smoking Cessation Pipeline
7.1 Novel Vaccines Will Target Nicotine Addiction
7.1.1 NicVAX (Nabi Biopharmaceuticals)
7.1.2 NIC002 (Cytos Biotechnology/Novartis)
7.1.3 TA-NIC (Celtic Pharma)
7.1.4 Niccine (Independent Pharmaceutica)
7.2 Expert Opinion on Nicotine Vaccines from Dr Raafat Fahim, President and Chief Executive Officer, Nabi Biopharmaceuticals
7.2.1 Vaccines in the Pipeline for Nicotine Addiction
7.2.2 NicVAX Nicotine Vaccine
7.2.3 Other Nicotine Vaccines
7.3 Monoamine Oxidase Inhibitors
7.3.1 EVT 302 (Evotec)
7.3.2 Selegiline (National Institute on Drug Abuse [NIDA])
7.4 Glycine Antagonists
7.5 Opiate Antagonists and Agonists
7.6 Dopamine D3 Antagonists
7.7 Nicotinic Ligands
7.8 Dopamine Uptake Inhibitors
7.9 Cannabinoid Receptor 1 Antagonists

8 Conclusions
8.1 Smoking is a Global Pandemic of Enormous Proportions
8.2 Smoking Cessation
8.3 The Smoking Cessation Market in 2008
8.4 World Smoking Cessation Market, 2009-2024
8.5 Leading Eight Smoking Cessation Markets and BRIC

List of Tables
Table 2.1 Nicotine Replacement Therapy Types
Table 2.2 Nicorette NRT Brands (Johnson & Johnson/Takeda)
Table 2.3 Nicabate/NicoDerm/Nicorette/NiQuitin NRT Brands (GSK)
Table 2.4 Novartis NRT Brands
Table 2.5 Other NRT Brands
Table 2.6 Key Drugs Prescribed Off-Label for Smoking Cessation
Table 3.1 World Smoking Cessation Market Sales, 2007-2008
Table 3.2 Leading Smoking Cessation Product Types, 2007-2008
Table 3.3 Leading Smoking Cessation Brands, 2007
Table 3.4 Leading Manufacturers of Smoking Cessation Products, 2007
Table 3.5 World Smoking Cessation Market Forecast, 2009-2014
Table 3.6 World Smoking Cessation Market Forecast, 2015-2024
Table 3.7 Smoking Cessation Product Type Sales Forecast, 2009-2014
Table 3.8 Smoking Cessation Product Type Sales Forecast, 2015-2024
Table 4.1 Leading Eight Smoking Cessation Markets, 2007-2008
Table 4.2 Smoking Cessation Country Markets Forecasts, 2009-2014
Table 4.3 Smoking Cessation Country Markets Forecasts, 2015-2024
Table 4.4 US Smoking Cessation Market Sales, 2007-2008
Table 4.5 Leading US Smoking Cessation Product Types, 2007-2008
Table 4.6 US Smoking Cessation Product Type Sales Forecast, 2009-2014
Table 4.7 US Smoking Cessation Product Type Sales Forecast, 2015-2024
Table 4.8 Leading Canadian Smoking Cessation Product Types, 2007
Table 4.9 Leading UK Smoking Cessation Product Types, 2007
Table 4.10 Leading French Smoking Cessation Product Types, 2007
Table 4.11 Leading Swedish Smoking Cessation Product Types, 2007
Table 4.12 Leading German Smoking Cessation Product Types, 2007
Table 4.13 Leading Australian Smoking Cessation Product Types, 2007
Table 5.1 BRIC Smoking Cessation Markets, 2007 & 2024
Table 6.1 SWOT Chart for the Smoking Cessation Market
Table 6.2 Smoking Prevalence and Smoking Cessation Revenue Per Smoker in Twenty Countries with Highest Number of Smokers
Table 7.1 Key Smoking Cessation Pipeline Products
Table 8.1 Smoking Cessation Country Markets 2008 Sales and CAGR, 2008-2024

List of Figures
Figure 3.1 Leading Smoking Cessation Product Types, 2007
Figure 3.2 Leading Smoking Cessation Brands, 2007
Figure 3.3 Leading Manufacturers of Smoking Cessation Products, 2007
Figure 3.4 Global Smoking Cessation Market Forecast, 2009-2024
Figure 3.5 Smoking Cessation Product Type Sales Forecast, 2009-2024
Figure 3.6 Smoking Cessation Product Type Sales & Market Share, 2007, 2014, 2019 and 2024
Figure 3.7 Nicotine Replacement Therapies Sales Forecast, 2009-2024
Figure 3.8 Chantix/Champix Sales Forecast, 2009-2024
Figure 4.1 2007 Smoking Cessation Market Share by Country
Figure 4.2 2014 Smoking Cessation Market Share by Country
Figure 4.3 2019 Smoking Cessation Market Share by Country
Figure 4.4 2024 Smoking Cessation Market Share by Country
Figure 4.5 Leading US Smoking Cessation Product Types, 2007
Figure 4.6 US Smoking Cessation Market Forecast, 2009-2024
Figure 4.7 US Nicotine Replacement Therapies Sales Forecast, 2009-2024
Figure 4.8 Chantix (US) Sales Forecast, 2009-2024
Figure 4.9 Canadian Smoking Cessation Market Forecast, 2009-2024
Figure 4.10 UK Smoking Cessation Market Forecast, 2009-2024
Figure 4.11 French Smoking Cessation Market Forecast, 2009-2024
Figure 4.12 Swedish Smoking Cessation Market Forecast, 2009-2024
Figure 4.13 German Smoking Cessation Market Forecast, 2009-2024
Figure 4.14 Australian Smoking Cessation Market Forecast, 2009-2024
Figure 4.15 Japanese Smoking Cessation Market Forecast, 2009-2024
Figure 5.1 BRIC Smoking Cessation Markets CAGR, 2008-2024
Figure 5.2 Brazilian Smoking Cessation Market Forecast, 2009-2024
Figure 5.3 Russian Smoking Cessation Market Forecast, 2009-2024
Figure 5.4 Indian Smoking Cessation Market Forecast, 2009-2024
Figure 5.5 Chinese Smoking Cessation Market Forecast, 2009-2024
Figure 6.1 Twenty Countries with Highest Number of Tobacco Smokers
Figure 8.1 Global Smoking Cessation Market Forecast, 2009-2024