Advertisement

Topics

DNA-FISH Probes - Biotech, Pharma and Life Science Channel

11:50 EDT 17th August 2017 | BioPortfolio

Fluorescent in situ hybridization (FISH) is a sensitive and accurate technique that allows the detection of chromosome aberrations. In this method, a single-stranded fluorescent-labeled nucleic acid sequence (probe) complementary to a target genomic sequence is hybridized to metaphase chromosomes and interphase nuclei to detect the presence and absence of a given abnormality. FISH complements traditional cytogenetic karyotype analysis.  The chief advantage of FISH is that is can be applied to non-dividing cells and a variety of specimen types.  FISH is a method of choice for diagnosis, prognosis, treatment response, and minimal residual disease detection in hematopoietic neoplasms (leukemia, lymphomas, multiple myeloma, and myelodysplasia) and solid tumors (breast cancer, non-small cell lung cancer, colorectal cancer, and cervical cancer).

Source: http://cancergenetics.com/cgi-research/dna-fish-probes/

PubMed Articles [5002 Associated PubMed Articles listed on BioPortfolio]

Development of a SYBR Green I real-time PCR for the detection of the orf virus.

Orf is a non-systemic, ubiquitous disease of sheep and goats caused by the orf virus (ORFV). ORFV occasionally causes cutaneous lesions in humans in contact with infected animals. In the present study...

Fullerene C60 Penetration into Leukemic Cells and Its Photoinduced Cytotoxic Effects.

Fullerene C60 as a representative of carbon nanocompounds is suggested to be promising agent for application in photodynamic therapy due to its unique physicochemical properties. The goal of this stud...

Mechanism of anti-Vibrio activity of marine probiotic strain Bacillus pumilus H2, and characterization of the active substance.

Vibriosis is a major epizootic disease that impacts free-living and farmed fish species worldwide. Use of probiotics is a promising approach for prevention of Vibrio infections in aquaculture. A probi...

PCM and TAT co-modified liposome with improved myocardium delivery: in vitro and in vivo evaluations.

In this study, PCM and TAT co-modified liposome was developed as a novel drug carrier for myocardium delivery with evaluation of its in vitro and in vivo properties. Liposomes containing fluorescent p...

N-Butyl-2-cyanoacrylate-based injectable and in situ-forming implants for efficient intratumoral chemotherapy.

The local delivery of chemotherapeutic drugs to tumor sites is an effective approach for achieving therapeutic drug concentrations in solid tumors. Injectable implants with the ability to form in situ...

Capillary electrophoresis coupled to mass spectrometry employing hexafluoro-2-propanol for the determination of nucleosides and nucleotide mono-, di- and tri-phosphates in baby foods.

The present work describes a method for the simultaneous determination of unmodified nucleosides and nucleotide mono-, di- and tri-phosphates by capillary electrophoresis coupled to mass spectrometry ...

Three monogeneans parasitic on marine sciaenid fish from Peru including description of Cynoscionicola veranoi n. sp. (Microcotylidae), and redescription of C. americanus Tantaleán, Martínez and Escalante, 1987 and Hargicotyle sciaenae Oliva and Luque, 1989 (Diclidophoridae).

Cynoscionicola veranoi n. sp. (Monogenea: Microcotylidae) is described based on specimens collected from the gills of lorna drum Sciaena deliciosa (Tschudi, 1846) (Sciaenidae) from Peru. The new speci...

Molecular characterization and functional analysis of a glutathione peroxidase gene from Aphelenchoides besseyi (Nematoda: Aphelenchoididae).

Aphelenchoides besseyi, the nematode agent of rice tip white disease, causes huge economic losses in almost all the rice-growing regions of the world. Glutathione peroxidase (GPx), an esophageal gland...

Population structure of the monogenean, Paramazocraes thrissocles (Mazocraeidae) on the gills of clupeoid fish, Thryssa mystax of Visakhapatnam coast, Bay of Bengal.

An investigation was undertaken on the population biology of the mazocraeid monogenean Paramazocreas thrissocles occurring on the gills of the engraulid fish Thryssa mystax at Visakhapatnam coast , Ba...

Diplectanids (Monogenea) parasitic on sciaenid fish from Peru with the proposal of Pseudorhamnocercoides n. gen., the description of Rhamnocercus dominguesi n. sp. and the redescription of Rhamnocercoides menticirrhi Luque and Iannacone, 1991.

Rhamnocercoides menticirrhi Luque and Iannacone, 1991 is redescribed from newly collected material of snakehead kingcroaker Menticirrhus ophicephalus (Jenyns, 1840) from Peru, and as a result of this ...

News Articles [815 Associated News Articles listed on BioPortfolio]

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo

Developmental deconvolution of complex organs and tissues at the level of individual cells remains challenging. Non-invasive genetic fate mapping has been widely used, but the low number of distinct f...

Abcam and TTP Labtech Collaborate to Develop sol-R Reagent Kits

<!--[if gte mso 9]><xml> </xml><![endif]--><!--[if gte mso 9]><xml> Normal 0 false false false EN-GB X-NONE X-NONE ...

Exiqon AS Medical Equipment Deals and Alliances Profile [Report Updated: 12072017] Prices from USD $250

SummaryExiqon A/S Exiqon, a subsidiary of Qiagen NV is a medical device company that develops, manufactures and markets molecular diagnostic test products. The company's product categories include mic...

Latency of seizures determined by diet

(Hiroshima University) Scientists are increasingly appreciating estrogen's role in brain health. The latest research from Hiroshima University connecting DHA synthesis to estrogen production, and cons...

Super-photostable fluorescent labeling agent for super-resolution microscopy

(Institute of Transformative Bio-Molecules (ITbM), Nagoya University) Chemists at ITbM, Nagoya University have developed a super-photostable fluorescent dye, PhoxBright 430 (PB430), to visualize cellu...

Recent Awards of Multiple U.S. Patents Reinforce 
Spectro Scientific’s Leadership Role in Fluid Analysis Solutions

Spectro Scientific has been awarded three U.S. patents covering a spectrum of analysis technologies ranging from portable instruments and software to online sensors.  Patent US9228956, &ldqu...

Comparing the jaws of porcupine fish reveals three new species

(Smithsonian Tropical Research Institute) Researchers at the Smithsonian Tropical Research Institute and colleagues compared fossil porcupine fish jaws and tooth plates collected on expeditions to Pan...

Injecting manure instead of spreading on surface reduces estrogen loads

(Penn State) With water quality in the Chesapeake Bay suffering from excess nutrients and fish populations in rivers such as the Susquehanna experiencing gender skewing and other reproductive abnormal...

Fish database could help eliminate the ultimate bait and switch

(American Chemical Society) Fish fraud, the misrepresentation of cheaper fish as more expensive ones, is a rampant problem worldwide. Now in a study appearing ACS' Journal of Agricultural and Food Che...

Understanding how fish grow their hearts could help humans, professor finds

(University of Guelph) A University of Guelph professor has identified a protein that enables fish to change the size of their hearts based on the temperature of the water. Understanding how fish are ...

Events [0 Results]

None

Companies [35 Associated Companies listed on BioPortfolio]

ReadCoor, Inc.

ReadCoor is leading the next generation of omics by delivering the first panomic spatial sequencing platform to the global audience of researchers, clinicians, pharma and diagnost...

Quidel Corporation

Quidel Corporation serves to enhance the health and well being of people around the globe through the development of rapid diagnostic solutions that can lead to improved patient o...

Safe Catch

Safe Catch is a new mission driven company that makes canned tuna like no other. Safe Catch invented a breakthrough technology to test fish individually for mercury – and no ...

Immunetics Incorporated

Our accomplishments include the development of patented instruments such as the MiniblotterÒ for Western Blot, spoligotyping, and other multi-probe membrane assays, a new Flow Cell for microarray hyb...

Orion Energy Systems, Inc.

Orion is leading the transformation of commercial and industrial buildings with state-of-the-art energy efficient lighting systems and retrofit lighting solutions. Orion manufactu...

Catabasis Pharmaceuticals

Catabasis is dedicated to the discovery and development of innovative, effective and safe medicines to treat inflammatory and metabolic diseases. The company has assembled a team ...

Allele Biotechnology & Pharmaceuticals, Inc.

Allele Biotechnology and Pharmaceuticals, Inc. is a private, San Diego-based company that explores the mechanisms of biological processes to develop technologies and products for ...

In-Situ Inc.

Nutter McClennen & Fish LLP

Nutter McClennen & Fish LLP represents an international roster of innovative clients involved in a range of sophisticated technologies in the medical device, biotechnology and pha...

Verlasso

Verlasso®, the world’s first provider of harmoniously raised fish, is the first and only ocean-raised farmed Atlantic salmon to receive the yellow “Good Alternativeâ...

Clinical Trials [614 Associated Clinical Trials listed on BioPortfolio]

Effect of Oily Fish Intake, Sex, Age, BMI, and APOE Genotype on Plasma Long Chain n-3 Fatty Acid Composition

The purpose of this study is to investigate the effect of habitual oily fish intake, sex, age, BMI, and APOE genotype on plasma long chain n-3 fatty acid composition.

Egg White for Phosphorus Control in Haemodialysis Patients

To evaluate the effect on phosphatemia in hemodialysis patients of replacing the meat or fish included in two meals a week with an amount of egg white containing the same quantity of prote...

Pre-Treatment of Highly Suspicious Pigmented Skin Lesions With Interleukin-2

This study is meant to assess the use of intralesional IL-2 to modulate the immunological response to suspected melanoma, or melanoma in situ, in an effort to increase lymphocyte infiltrat...

ARQ 087 in Subjects With FGFR2 Gene Fusion Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma

This pivotal, open-label, single-arm study will evaluate the anti-cancer activity of ARQ 087 by Objective Response Rate (ORR) by central radiology review as per RECIST v1.1 in subjects wit...

Evaluation of Trastuzumab in Combination With Lapatinib or Pertuzumab in Combination With Trastuzumab-Emtansine to Treat Patients With HER2-positive Metastatic Colorectal Cancer

This is a Phase II multi-center 2-sequential cohorts trial, designed to assess the objective response rate of two anti HER2 combination in advanced disease CRC patients harbouring an ampli...

Proteomics Investigation of Subpopulation of Exosomes Released From Sepsis-damaged Organs-double-markers Identification of Specific Organ Failure Using Fluorescent Nanoparticle Tracking Analysis

Systematic establishment of exosome proteomics in co-culture medium and clinical sepsis specimens will be done. Ubiquitination-autophagy-apoptosis biomarkers in exosomes will be detected a...

Study of Performance of Confocal Endomicroscope With Fluorescein Imaging Agent in the Colon

The overall aim of this research project is to evaluate the imaging performance of a confocal endomicroscope. Fluorescein, an FDA-approved topical fluorescent dye, will be used to provide ...

A2 AR as a Novel Biomarkers for Physician Decision-making Improvement Evaluation's Patients With Suspected Acute Coronary Syndrome But Negative Troponin.

One proposed strategy is the stratification of troponin-negative patients with biomarker testing at presentation to facilitate the clinically-appropriate rapid discharge from the emergency...

Intraoperative Radiation Therapy (IORT) in DCIS

The goal of this study is to examine the role of Intraoperative Radiotherapy (IORT) in Ductal Carcinoma In-Situ (DCIS) and to improve the understanding of the clinical, radiographic, and p...

Microbiome Involvement With Barrett's Esophagus and Progression to Esophageal Adenocarcinoma

This study will examine the hypothesis that altered esophageal microbiome leads to the development of esophageal adenocarcinoma (EAC). The aims of the project are, firstly the confirmation...

Videos

None available.

Medical and Biotech [MESH] Definitions

A type of IN SITU HYBRIDIZATION in which target sequences are stained with fluorescent dye so their location and size can be determined using fluorescence microscopy. This staining is sufficiently distinct that the hybridization signal can be seen both in metaphase spreads and in interphase nuclei.

The simultaneous identification of all chromosomes from a cell by fluorescence in situ hybridization (IN SITU HYBRIDIZATION, FLUORESCENCE) with chromosome-specific florescent probes that are discerned by their different emission spectra.

A condition in which abnormal cells have not spread outside the duct, lobule, or nipple to other tissues of the breast. There are 3 types of breast carcinoma in situ: DUCTAL CARCINOMA IN SITU; LOBULAR CARCINOMA IN SITU; and PAGET DISEASE OF THE NIPPLE

A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.

Fish of the genera ONCORHYNCHUS and Salmo in the family SALMONIDAE. They are anadromous game fish, frequenting the coastal waters of both the North Atlantic and Pacific. They are known for their gameness as a sport fish and for the quality of their flesh as a table fish. (Webster, 3d ed).

Quick Search
Advertisement
 

Relevant Topics

Bioinformatics
Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...

Leukemia
Leukemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader grou...

review and buy DNA-FISH Probes market research data and corporate reports here

Channels Quicklinks