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Clearing and Opening the Upper Airway
Management Forum - highest quality conference, seminar and knowledge-based experiences
Since 1983, Management Forum have built a reputation on providing the highest quality conference, seminar and knowledge-based experiences for leading professionals in some of the world's most demanding industries. Based in Woking, Surrey, UK, Ma...
Autism affects half a million people in the UK. Men are affected more than women. People with autism have said that the world, to them, is a mass of people, places and events which they struggle to make sense of, and which can cause them considerable a...
Vitamin C (ascorbic acid) plays a role in collagen, carnitine, hormone, and amino acid formation. It is essential for wound healing and facilitates recovery from burns. Vitamin C is also an antioxidant, supports immune function, and facilitates the absor...
Swine flu is the common name given to a relatively new strain of influenza (flu) that caused a flu pandemic in 2009-2010. It is also referred to as H1N1 influenza (because it is the H1N1 strain of virus). The H1N1 flu virus will be one of the main vi...
Trigeminal Neuralgia (TN) is an extremely severe facial pain that tends to come and go unpredictably in sudden shock-like attacks. The pain is often described as stabbing, shooting, excruciating, burning, extremely strong. The pain usually lasts for a fe...
Technical Background Tumor necrosis factor (TNF) is a substance made by your body's immune system. People with inflammatory diseases such as rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, juvenile idiopathic arthritis, and ankylosing...
Tinnitus causes people to hear constant sounds in one ear, both ears or in their head. Tinnitus is the medical name for the perception of noise in one ear, both ears or in the head. The noise comes from inside the body rather than an outside source. Pe...
Smoking tobacco and cigarettes has long been associated with lung cancer and other respiratory conditions such as COPD. Since this link has become common knowledge, there has extensive programs to help people quit smoking, as well as political campaigns...
Statins (HMG-CoA reductase inhibitors) - a class of drug used to lower cholesterol levels
Statins (or HMG-CoA reductase inhibitors) are a class of drug used to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. Increased cholesterol levels have been as...
2.8 million people in the UK have been diagnosed with diabetes in the UK and a further 850,000 people are undiagnosed. Diabetes is characterized by high blood glucose levels, resulting from a problem with Insulin (which is the natural compound that reg...
GlaxoSmithKline is the third largest pharmaceutical company in the world, based on annual sales, which reached $37,134m in 2009. Spread over 100 countries, GSK employs 96,500 people, 13,000 of which are dedicated to research and development of the the...
In biology, and specifically genetics, epigenetics is the study of changes in gene expression caused by mechanisms other than changes in the underlying DNA sequence – hence the name epi- (Greek: επί- over, above, outer) -genetics. Examp...
Vasculitis (plural: vasculitides) refers to a heterogeneous group of disorders that are characterized by inflammatory destruction of blood vessels. Vasculitis is primarily due to leukocyte migration and resultant damage, but can be secondary to other dis...
Stridor is a high pitched wheezing sound resulting from turbulent air flow in the upper airway. It is primarily inspiratory. It can be indicative of serious airway obstruction from severe conditions such as epiglottitis, a foreign body lodged in the airw...
Histone Deacetylase HDAC Inhibitors
Histone deacetylase (HDAC) inhibitors are emerging as a new class of potential anticancer agents for the treatment of solid and hematological malignancies. HDAC inhibition causes acetylated nuclear histones to accumulate in both tumor and normal tissues,...
Nonalcoholic Steatohepatitis NASH
Nonalcoholic steatohepatitis or NASH is a common, often “silent” liver disease. It resembles alcoholic liver disease, but occurs in people who drink little or no alcohol. The major feature in NASH is fat in the liver, along with inflammation...
Sleep apnea (AP-ne-ah) is a common disorder in which you have one or more pauses in breathing or shallow breaths while you sleep. Breathing pauses can last from a few seconds to minutes. They often occur 5 to 30 times or more an hour. Typically, normal b...
Wnt is an anti-apoptotic ligand for the Fz (frizzled) receptor on cell membranes
Wnt is an anti-apoptotic ligand for the Fz (frizzled) receptor on cell membranes, meaning it attaches to the Fz receptor and prevents cell death (in effect with other cellular stimuli). Wnt molecules are a family of proteins that act as a paracrine stimu...
Epilepsy is defined as a disorder of brain function characterized by recurrent seizures that have a sudden onset. (Oxford Medical Dictionary). A seizure is caused by a sudden burst of excess electrical activity in the brain, causing a tempora...
Pseudomonas aeruginosa Vaccines
Pseudomonas aeruginosa is an opportunistic gram-negative bacteria that lives in soil, water, and even in environments like hot tubs. For most healthy people, this bacteria seldom poses a problem. Pseudomonas aeruginosa is much more dangerous to population...
Systemic Lupus Erythematosus SLE
Lupus is an autoimmune disease characterized by acute and chronic inflammation of various tissues of the body. Because the antibodies and accompanying cells of inflammation can affect tissues anywhere in the body, lupus has the potential to affect a vari...
Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks. Over half of Bipolar cases develops before the age of 25. Bipolar...
Of all the types of Dementia, Alzheimer's disease is the most common, affecting around 465,000 people in the UK. Neurons in the brain die, becuase 'plaques' and 'tangles' (mis-folded proteins) form in the brain. People with Al...
