Anthrax Vaccines and Therapeutics - Biotech, Pharma and Life Science Channel
Anthrax is a zoonotic disease caused by the spore-forming bacterium Bacillus anthracis. The disease most commonly occurs in mammals (e.g., cattle, sheep, goats, camels, antelope. Anthrax occurs in humans when they are exposed to infected animals or tissue from infected animals or when they are directly exposed to B. anthracis, e.g. by intentional contamination. Depending on the route of infection, anthrax disease can occur in three forms: cutaneous, gastrointestinal, and inhalation.
Currently approved anthrax vaccines in the US and in the UK are Anthrax Vaccine Absorved (AVA) and Anthrax Vaccine Precipitated (AVP), respectively, require a subcutaneous six-dose primary immunization schedule. The complex vaccination scheme, local injection site reactions, the limited spectrum of protective efficacy and the threat of the use of anthrax as a biological weapon urged governments to sponsor considerable efforts to develop novel vaccines and therapeutic antibodies against anthrax. As a result, the development pipeline substantially has grown over the last years with next generation molecules.
News Articles
Sinovac to Host Conference Call to Report First Quarter 2013 Unaudited Financial Results
BEIJING, May 17, 2013 /PRNewswire/ -- Sinovac Biotech Ltd. (Nasdaq: SVA), a leading provider of vaccines in China, today announced that it will release its unaudited financial results for the...
Pennsylvania Physicians Urge State Legislators to Support Immunization Expansion Bill
HARRISBURG, Pa., May 16, 2013 /PRNewswire/ -- The Pennsylvania Pharmacists Association announced today that numerous physicians throughout the Commonwealth are urging state legislators to support Hous...
The World Small Animal Veterinary Association Recommends Canine VacciCheck
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Immunovaccine Announces Financial Results for the Quarter Ended March 31, 2013
HALIFAX, NOVA SCOTIA -- (Marketwired) -- 05/16/13 -- Immunovaccine Inc. ("Immunovaccine" or "IMV") (TSX VENTURE: IMV), a clinical stage vaccine company, today released its financial and operational...
Research Team Publishes New Methods for Synthetic Generation of Influenza Vaccines
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Sinovac Appoints Ernst & Young Hua Ming Llp China as External Auditor
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Prevalence of Flu and Use of Flu Shots Last Winter Fairly Typical of Last Decade
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Companies
Merck is a global healthcare leader working to help the world be well. Merck is known as MSD outside the United States and Canada. Through our prescription medicines, vaccines, biologic therapies, a...
Xenetic is a leading UK-based biopharmaceutical company providing leading-edge expertise in the development of a whole new generation of drugs and vaccines. Working with some of the largest pharma...
VGTI Florida is the Florida-funded expansion of Oregon Health & Science University's highly successful Vaccine and Gene Therapy Institute. Research at the facility will focus on v...
Etubics Corporation, based in Seattle, Wash., is a clinical stage bio-pharmaceutical company, which has developed a proprietary platform technology consisting of a next generation...
Fraunhofer USA CMB, a division of Fraunhofer USA, Inc., is a not-for-profit research organization whose mission is to develop safe and effective vaccines targeting infectious dise...
Profectus BioSciences, Inc. is a technology based vaccine company devoted to the treatment and prevention of chronic viral diseases with a goal of reducing morbidity and mo...
Genocea Biosciences is a vaccine discovery and development company targeting major infectious diseases with high unmet medical needs, in which T cell response helps confer protect...
Advaxis is a biotechnology company developing proprietary, live but attenuated Listeria monocytogenes (Listeria) vaccines that deliver engineered tumor antigens, which stimulate...
Genocea Biosciences is a vaccine discovery and development company targeting major infectious diseases with high unmet medical needs, in which T cell responses help confer protect...
Today's Merck is a global healthcare leader working to help the world be well. Merck is known as MSD outside the United States and Canada. Through our prescription medicines, vacc...
Clinical Trials
RATIONALE: Vaccines made from a person's white blood cells may help the body build an effective immune response. PURPOSE: This phase I trial is studying the side effects of vaccine therap...
Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy
Background: - Drugs given to treat cancer (chemotherapy) can weaken the human immune system. But it can also become weaker because of aging. Interleukin (IL)-7, a molecule produced natura...
GSK Biologicals is developing in partnership with the Malaria Vaccine Initiative at PATH a candidate malaria vaccine RTS,S/AS02 for the routine immunization of infants and children living...
A Study to Assess the Safety of Live Intranasal Sendai Virus Vaccine in Children and Toddlers
Croup is an illness of young children that is caused by a virus. With this illness, the child has fever, cough, and hoarseness. Although the illness usually gets better in 2 to 4 days, so...
Vitamin A Supplementation With Routine Childhood Vaccines and Mortality and Morbidity
Vitamin A supplementation (VAS) is important for the immune system and may interact with different childhood vaccinations. We have hypothesized that the improved survival after VAS may dep...
MMR and Varicella Vaccine in Premature Infants
This research is designed to address the question, "Does the relative deficit in vaccine immunogenicity in extremely premature infants persist beyond the first 6 months of life?" We propos...
Study to Eliminate Hib Carriage in Rural Alaska Native Villages
Hib disease rates in rural Alaska before introduction of HIb conjugate vaccine were among the highest in the world. Since vaccine introduction, rates have fallen by 90% but the disease ha...
Rituximab in the Treatment of Graves' Disease
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Antibody Responses to Pneumococcal Vaccines Among HIV-Infected Adults.
Streptococcus pneumoniae is the major cause of bacterial infection in HIV-infected patients. The current pneumococcal vaccine is poorly efficacious in patients with a CD4 cell count lower...
Monoclonal Antibody for Treatment of Inhalation Anthrax
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PubMed Articles
Anthrax is a bacterial disease caused by the aerobic sporeforming bacterium Bacillus anthracis, which is an important pathogen owing to its ability to be used as a terror agent. B. anthracis spores ca...
Using a capillary isoelectric focusing-whole column imaging detection (CIEF-WCID) method the isoelectric points (pI) of complete intact polioviruses were determined. The polio viruses that were analyz...
Cancer immunotherapies, their safety and toxicity.
Introduction: Cancer immunotherapy encompasses a wide range of treatment modalities that harness the anti-tumor effects of the immune system. Some immunotherapies broadly activate the immune system wh...
Designing CAF-adjuvanted dry powder vaccines: Spray drying preserves the adjuvant activity of CAF01.
Dry powder vaccine formulations are highly attractive due to improved storage stability and the possibility for particle engineering, as compared to liquid formulations. However, a prerequisite for fo...
This report summarizes recommendations approved on February 21, 2013, by the Advisory Committee on Immunization Practices (ACIP) for the use of influenza vaccines. An expanded 2013 ACIP influenza vacc...
The 2009 swine-origin H1N1 influenza, though antigenically novel to the population at the time, was antigenically similar to the 1918 H1N1 pandemic influenza, and consequently was considered to be "ar...
By employing modified Cornell model, we have evaluated the potential of adjunctive immunotherapy with DNA vaccines to shorten the tuberculosis chemotherapy period and reduce disease reactivation. We d...
Outer-membrane vesicles (OMVs) have inherent adjuvant properties, and many vaccines use OMV as vaccine components. Utilizing the adjuvant properties of OMV could lead to the formulation of vaccines th...
BACKGROUND: Reports of data mining results as an initial indication of a prospectively detected safety signal in the US Vaccine Adverse Event Reporting System (VAERS) have been limited. In April 2010...
The immune system has evolved regulatory mechanisms to control immune responses to self-antigens. Regulatory T (Treg) cells play a pivotal role in maintaining immune tolerance, but tumour growth is as...
Videos
Why Wasn't H1N1 Vaccine Available Before School Started?
The H1N1 emergency demonstrated that we need to produce vaccines and medicines faster and less expensively. Chicken eggs aren't the answer. This video was sp...
Medical and Biotech [MESH] Definitions
Tuberculosis Vaccines
Vaccines or candidate vaccines used to prevent or treat TUBERCULOSIS.
Ebola Vaccines
Vaccines or candidate vaccines used to prevent EBOLA HEMORRHAGIC FEVER.
Dengue Vaccines
Vaccines or candidate vaccines used to prevent infection with DENGUE VIRUS. These include live-attenuated, subunit, DNA, and inactivated vaccines.
West Nile Virus Vaccines
Vaccines or candidate vaccines used to prevent infection with WEST NILE VIRUS.
Electrochemotherapy
A treatment modality that uses pulsed electrical currents to permeabilize cell membranes (ELECTROPORATION) and thereby enhance the uptake of chemotherapeutic agents, vaccines, or genes into the body's cells.
