Chronic neutropenia - Biotech, Pharma and Life Science Channel
PubMed Articles
The aim of the study is to evaluate the efficacy and safety of a three-drug chemotherapy regimen including gemcitabine, carboplatin, and paclitaxel as induction therapy in clinical stage III non-small...
Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults in Western countries. It is characterized by heterogeneous clinical course of the disease and new prognostic factors are still...
This study sought to examine the efficacy of ranolazine versus placebo on weekly angina frequency and sublingual nitroglycerin use in subjects with type 2 diabetes mellitus, coronary artery disease (C...
Effects of Hominis placenta on LPS-induced cell toxicity in BV2 microglial cells.
ETHONOPHARMACOLOGICAL RELEVANCE: Hominis placenta (HP) dried placenta extracted from pregnant women after delivery has been widely used to treat chronic inflammatory diseases. HP has been reported to...
Abstract Significance: Chronic obstructive pulmonary disease (COPD) is predominantly a tobacco smoke-triggered disease with features of chronic low-grade systemic inflammation and aging (inflammaging)...
Objective: The aims of this interventional were to evaluate the efficacy of functional endoscopic sinus surgery (FESS) -oriented multimodality treatment in chronic rhinosinusitis (CRS) patients with a...
There are various forms of periodontitis characterised as an inflammatory disease with more or less expressed alteration of genetic immunological components and associated with local as well as psycho...
Genetic Characterization of SF3B1 Mutations in Single Chronic Lymphocytic Leukemia Cells.
BACKGROUND AND OBJECTIVE: We sought to determine the relationship between chronic respiratory disease, cardiovascular disease, and mortality in a nationally representative cohort of the US population...
News Articles
Shorter Duration Steroid Therapy May Offer Similar Effectiveness In Reducing COPD Exacerbations
Among patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) requiring hospital admission, a 5-day glucocorticoid treatment course was non-inferior (not worse than) to a 14-...
COPD patients are more oliley to suffre from depression
Patients suffering from chronic obstructive pulmonary disease (COPD) typically suffer from depression more frequently than those without COPD, resulting in higher levels of disability and illness and...
Pain a Common Problem for People With COPD
TUESDAY, May 21 (HealthDay News) -- Chronic obstructive pulmonary disease (COPD) patients experience a significant amount of pain, new research suggests. Pain levels are nearly on par with the kind o...
Study: Use of bronchodilators linked with increased risks of cardiovascular events
A study of older patients with chronic obstructive pulmonary disease (COPD) suggests that new use of the long-acting bronchodilators β-agonists and anticholinergics was associated with similar increa...
ORLANDO, Fla., May 21, 2013 /PRNewswire/ -- Janssen R&D Ireland (Janssen) today announced primary efficacy and safety results from the global Phase 3 PROMISE study demonstrating that use of t...
Losing weight may ease chronic heartburn
(HealthDay)—Obese and overweight men and women who suffer from heartburn often report relief when they lose weight, a new study shows.
The Interactive Effects On Neurocognition Of Alcohol Consumption, Smoking And Age
Treatment for alcohol use disorders works best if the patient actively understands and incorporates the interventions provided in the clinic. Multiple factors can influence both the type and degree of...
(California Institute of Technology) A team of researchers led by biologists at the California Institute of Technology has found that, in mouse models, the molecule microRNA-146a acts as a critical re...
Inflammation is associated with depression in COPD patients
(American Thoracic Society) Depression is common in patients with chronic obstructive pulmonary disease (COPD) and has been linked with disease severity and impaired quality of life. Now, for the firs...
Study shows COPD is associated with significant and persistent pain
(American Thoracic Society) Chronic obstructive pulmonary disease is primarily associated with the respiratory symptoms that are its hallmark, but in fact, patients who struggle with the disease also...
Events
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Companies
Acorda Therapeutics, Inc. was established in March 1995 to develop therapeutic products for spinal cord injury ("SCI") and other central nervous system disorders. Acorda is focusing its initial develo...
ALung Technologies, Inc. is commercializing artificial lung devices for the treatment of acute and chronic respiratory disorders. The company's Hemolung System, designed to replace or supplement the u...
Neovacs is a French biotechnology company focused on active immunotherapy for autoimmune and inflammatory diseases and cancer. Neovacs is a spin-off from Université Pierre et Marie Curie in P...
Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...
Forest Laboratories, Inc. & Ironwood Pharmaceuticals, Inc.
Ironwood Pharmaceuticals (NASDAQ: IRWD) is an entrepreneurial pharmaceutical company dedicated to the art and science of great drugmaking. Linaclotide, Ironwood's GC-C agon...
National Fibromyalgia & Chronic Pain Association
NFMCPA, a not-for-profit organization, supports individuals living with fibromyalgia and other chronic pain illnesses by raising awareness through community outreach, education, a...
Ironwood Pharmaceuticals, Inc.
Ironwood Pharmaceuticals (NASDAQ: IRWD) is an entrepreneurial pharmaceutical company dedicated to the art and science of great drugmaking. Linaclotide, Ironwood's GC-C agonist, is...
Catasys, Inc. provides specialized behavioral health management services to health plans, employers and unions through a network of licensed and company managed health care provid...
Almirall, S.A. and Ironwood Pharmaceuticals, Inc.
Ironwood Pharmaceuticals (NASDAQ: IRWD) is an entrepreneurial pharmaceutical company dedicated to the art and science of great drugmaking. Linaclotide, Ironwood's GC-C agon...
Paradigm Medical Management, Inc
Paradigm Medical Management, Inc (PMM) headquartered in Los Angeles, California, is an industry leader focused on the development, implementation and management of hospital outpat...
Clinical Trials
Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants
To determine whether or not inhaled nitric oxide (iNO) safely decreases the incidence of chronic lung disease (CLD) in premature infants.
Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain
Noxious stimuli occurring intraoperatively and postoperatively generate central sensitization, decreasing pain thresholds and ultimately increasing analgesic requirements. The pathophysiol...
The purpose of the study is to determine the safety, pharmacokinetics and efficacy of orally administered VX-135 with ribavirin in treatment naive subjects with chronic hepatitis C infecti...
The Study of the Safety and Efficacy of Ampligen in Chronic Fatigue Syndrome
multi-center, double-blind, randomized, placebo-controlled study of the safety and efficacy.
The purpose of this study is to assess the efficacy of a short course of therapy (24 weeks) versus standard 48 week treatment in previously untreated adult participants with chronic hepati...
Mesenchymal Stromal Cells (MSCs) for the Treatment of Graft Versus Host Disease (GVHD)
This is a bicentric, prospective, non randomized study. Pediatric and adult patients will be treated. Rationale: MSC have shown promising effects by reversal of severe therapy-resistant a...
RATIONALE: Sorafenib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the cancer. PURPOSE: This randomized phase I...
Treatment with growth hormone (GH; a hormone made by the body that stimulates growth) has been shown to be helpful in treating children with chronic kidney disease who fail to grow. The a...
The purpose of this study is to see which of two doses of PEG (polyethylene glycol) interferon alfa-2b in combination with Ribavirin for 48 weeks is more effective at elimination of hepati...
Spinal Cord Stimulation for Low Back Pain
The purpose of this study is to assess the acute and chronic effectiveness of the Advanced Bionics Precision(TM) Spinal Cord Stimulation System in subjects with failed back surgery syndrom...
Videos
Save Ariana-Leilani!
Ariana- Leilani is a 9-year old dual German-American citizen who has been diagnosed with Severe Chronic Neutropenia, a life-threatening disease affecting onl...
Medical and Biotech [MESH] Definitions
Wasting Disease, Chronic
A transmissible spongiform encephalopathy (prion disease) of DEER and elk characterized by chronic weight loss leading to death. It is thought to spread by direct contact between animals or through environmental contamination with the prion protein (PRIONS).
Toxicity Tests, Chronic
Experiments designed to determine the potential toxic effects of a long-term exposure to a chemical or chemicals.
Post-concussion Syndrome
The organic and psychogenic disturbances observed after closed head injuries (HEAD INJURIES, CLOSED). Post-concussion syndrome includes subjective physical complaints (i.e. headache, dizziness), cognitive, emotional, and behavioral changes. These disturbances can be chronic, permanent, or late emerging.
American Public Health Association
Professional organization concerned with issues affecting personal and environmental health, including federal and state funding for health programs, programs related to chronic and infectious diseases, and professional education in public health.
Calgranulin A
A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.
