Diseasemodifying drugs - Biotech, Pharma and Life Science Channel

20:16 EDT 26th April 2015 | BioPortfolio

PubMed Articles [4667 Associated PubMed Articles listed on BioPortfolio]

Securing opioid substitution treatment access and quality for people who inject drugs.

The relevance of epigenetics to occlusive cerebral and peripheral arterial disease.

Athero-thrombosis of the arteries supplying the brain and lower limb are the main causes of stroke and limb loss. New therapies are needed to improve the outcomes of athero-thrombosis. Recent evidence...

Topical NSAIDs Effect on Corneal Sensitivity.

Topical nonsteroidal antiinflammatory drugs (NSAIDs) are administered topically for a variety of ophthalmologic conditions. Brand diclofenac and brand ketorolac were previously shown to have topical a...

Is this your (paediatric patient's) brain on (anaesthetic) drugs?: The search for a potential neurological phenotype of anaesthesia-related neurotoxicity in humans.

Overlapping Dopaminergic Pathway Genetic Susceptibility to Heroin and Cocaine Addictions in African Americans.

Drugs of abuse activate the mesolimbic dopaminergic pathway. Genetic variations in the dopaminergic system may contribute to drug addiction. Several processes are shared between cocaine and heroin add...

Transmission of Hepatitis C Virus among Prisoners, Australia, 2005-2012.

Hepatitis C virus (HCV) is predominantly transmitted between persons who inject drugs. For this population, global prevalence of HCV infection is high and incarceration is common and an independent ri...

Advances in Exotic Mammal Clinical Therapeutics.

It is important that veterinarians treating exotic companion mammals stay abreast of the latest developments relating to medications and drug delivery approaches for safety, efficacy and welfare issue...

Hippo pathway gene mutations in malignant mesothelioma: revealed by RNA and targeted exon sequencing.

Malignant mesothelioma (MM) is an aggressive neoplasm causatively associated with exposure to asbestos. MM is rarely responsive to conventional cytotoxic drugs, and the outcome remains dismal. It is, ...

Deuterated drugs: Relief from racemization.

Radiofrequency catheter ablation for atrial fibrillation.

Antiarrhythmic drugs are the first-line treatment for atrial fibrillation (AF); as a result, catheter ablation usually is not considered until a patient is experiencing symptomatic AF refractory to at...

News Articles [4797 Associated News Articles listed on BioPortfolio]

Trivedi Science™ Has Started Scientific Research to Create More Effective Pharmaceuticals and Nutraceuticals

Henderson, NV (PRWEB) April 26, 2015 From March 18th, 2015 toward the middle of April, Mahendra Trivedi and his wife, Trivedi Master™ Dahryn Trivedi, spent a month traveling in India to find s...

RPT-DEALTALK-Drug overlaps, shortages may complicate Teva bid for Mylan

NEW YORK, April 24 (Reuters) - Teva Pharmaceutical Industries' bid for Mylan NV would create a company controlling nearly 25 percent of the U.S. generics market, including drugs in short supply, accor...

EMA/CHMP recommends approval for seven generics

A total of seven generic drugs were recommended for approval at the April 2015 meeting of the European…

Teens With History of Self-Poisoning Face Greater Suicide Risk

SATURDAY, April 25, 2015 -- Teens who survive self-poisoning with drugs are at a significantly increased risk for suicide over the following decade, a new study shows. "Self-poisoning in adolescence i...

Growing Antibiotic Shortages Threaten Patient Care

A disturbing new report shows that shortages of many important antibiotics have been worsening since 2007. Antibiotics accounted for 15% of all drug shortages from 2001-13, affecting 148 anti-infectiv...

Prices of MS Drugs Soaring, Study Finds

FRIDAY, April 24, 2015 -- The prices of multiple sclerosis drugs have skyrocketed in the past two decades, in some cases rising more than 700 percent, a new study shows. The huge price increases have ...

Drug overlaps, shortages may complicate Teva bid for Mylan

NEW YORK (Reuters) - Teva Pharmaceutical Industries' bid for Mylan NV would create a company controlling nearly 25 percent of the U.S. generics market, including drugs in short supply, according to in...

DEALTALK-Drug overlaps, shortages may complicate Teva bid for Mylan

NEW YORK, April 24 (Reuters) - Teva Pharmaceutical Industries' bid for Mylan NV would create a company controlling nearly 25 percent of the U.S. generics market, including drugs in short supply, accor...

Some Progestins May Hike Cancer; Some Estrogens May Ward it Off

A recent analysis of  long-term after-effects of a specific hormone replacement therapy (HRT)—non-physiologic hormones created by Wyeth—finds that a pattern observed while women took the drugs du...

Wider Use of Naloxone Could Cut Deaths From Drug Overdoses: CDC

FRIDAY, April 24, 2015 -- Allowing more emergency medical service (EMS) workers to administer the prescription drug naloxone could reduce the number of overdose deaths caused by opioid drugs, U.S. hea...

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Companies [241 Associated Companies listed on BioPortfolio]

Iris Pharma

Iris Pharma is a Contract Research Organizations (CROs) providing drug development services to Research Institutes, Pharmaceutical or Biotechnology Industries, to support the preclinical development a...

Proteo Biotech AG

The company researches, develops and markets compounds for biological and medical research as well as for use as pharmaceuticals. The main focus is on anti-inflammatory drugs, in ...

MedDay

MedDay is a privately held biotechnology company developing new drugs for nervous system disorders. The company was founded in 2011 by Frédéric Sedel, MD, PhD (Chief Executi...

Cerecor Inc.

Driven by an innovative team of industry experts and leading scientists, Cerecor aspires to develop neuroscience drugs that will make a difference. We are committed to improving t...

MediVector, Inc.

MediVector, Inc. is a Boston-based drug development company specializing in decreasing the time and cost of bringing drugs to market. The company complements its team’s clini...

Akaal Pharma Pty Ltd.

Akaal Pharma Pty Ltd (Akaal Pharma) is a clinical-stage drug discovery and development company focused on the development of novel small molecule drugs for the treatment of inflam...

Hydra Biosciences, Inc

Hydra Biosciences is a biopharmaceutical company developing molecular regeneration medicines, novel cardiovascular therapies and drugs targeting novel ion channels. Tapping the unharnessed power of th...

Voisin Consulting Life Sciences

Voisin Consulting assists biotechnology, pharmaceutical and biomedical companies in the design and implementation of innovative regulatory strategies to expedite product development programs such as d...

Prometheon Pharma

Prometheon Pharma is a biotechnology company housed in the globally #1-ranked Sid Martin Biotech Incubator at the University of Florida. Prometheon is dedicated to increasing pati...

ProteoTech Inc.

ProteoTech is a privately-held, drug development company that utilizes its amyloid expertise to discover and develop new drugs for treating misfolded protein disorders and amyloid...

Clinical Trials [186 Associated Clinical Trials listed on BioPortfolio]

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

The purpose of this study is to evaluate the pharmacokinetics (PKs) of antiretroviral (ARV) and tuberculosis (TB) medications in pregnant women and their infants. (Pharmacokinetics are the...

Clinical Trial of MK0683 in Combination With FDA Approved Cancer Drugs in Patients With Advanced NSCLC (MK0683-058)

This is a clinical trial to determine the safety and tolerability of MK0683 in combination with gemcitabine and cisplatin and/or carboplatin.

Vytorin Reexamination Study (0653A-174)

This survey is conducted for preparing application material for re-examination under the Pharmaceutical Affairs Laws and its Enforcement Regulation, its aim is to reconfirm the clinical us...

Cozaar XQ Re-examination Study (MK-0954-349)

This survey is conducted for preparing application material for re-examination under the Pharmaceutical Affairs Law and its Enforcement Regulation; its aim is to reconfirm the clinical use...

The Effects of the Drugs Used in Hypotensive Anaesthesia on Cochlea

The aim of this study is to find the Effects of Anesthetics Used in Hypotensive Anesthesia on Stapes Reflex and Distortion Product Auto Acoustic Emission.

When to Start Anti-HIV Drugs in Patients With Opportunistic Infections

The purpose of this study is to evaluate the effect of starting anti-HIV drugs in HIV infected patients who are being treated for opportunistic infections (OIs). This study will follow tw...

An Observational Study of Induction Therapy With Fuzeon (Enfuvirtide) in Combination With Antiretroviral Drugs in Patients With HIV-1 Infection

This multicenter, retrospective, observational study will evaluate the therapeut ic effectiveness of a strategy of induction with Fuzeon (enfuvirtide) within an optimized regimen of antire...

A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-182)

The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.

Investigation of Potential Drug-drug Interactions Between Faldaprevir and the Immunosuppressant Drugs Cyclosporine or Tacrolimus

The primary objective of this trial is to investigate the effect of multiple-dose faldaprevir (FDV) on the single-dose pharmacokinetics of cyclosporine or tacrolimus

Attention Deficit Hyperactivity Disorder Drugs Use Chronic Effects

The aim of the ADDUCE project is to investigate any adverse effects of methylphenidate (trade name ritalin) on growth, neurological system, psychiatric states and cardiovascular system ove...

Medical and Biotech [MESH] Definitions

Drugs used by veterinarians in the treatment of animal diseases. The veterinarian's pharmacological armamentarium is the counterpart of drugs treating human diseases, with dosage and administration adjusted to the size, weight, disease, and idiosyncrasies of the species. In the United States most drugs are subject to federal regulations with special reference to the safety of drugs and residues in edible animal products.

Drugs which have received FDA approval for human testing but have yet to be approved for commercial marketing. This includes drugs used for treatment while they still are undergoing clinical trials (Treatment IND). The main heading includes drugs under investigation in foreign countries.

The use of multiple drugs administered to the same patient, most commonly seen in elderly patients. It includes also the administration of excessive medication. Since in the United States most drugs are dispensed as single-agent formulations, polypharmacy, though using many drugs administered to the same patient, must be differentiated from DRUG COMBINATIONS, single preparations containing two or more drugs as a fixed dose, and from DRUG THERAPY, COMBINATION, two or more drugs administered separately for a combined effect. (From Segen, Dictionary of Modern Medicine, 1992)

Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here.

Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.

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