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Diseasemodifying drugs - Biotech, Pharma and Life Science Channel

06:28 EDT 28th August 2016 | BioPortfolio

PubMed Articles [4666 Associated PubMed Articles listed on BioPortfolio]

Sexual abstinence: What is the understanding and views of secondary school learners in a semi-rural area of North West Province, South Africa?

Among strategies to prevent HIV, other sexually transmitted infections (STIs) and unwanted pregnancies, are programs that promote sexual abstinence among adolescents. However, literature suggests that...

(177)Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment.

Metastatic bone lesion is a common syndrome of many cancer diseases in an advanced state. The major symptom is severe pain, spinal cord compression, and pathological fracture, associated with an obvio...

Multi-responsive magnetic microsphere of poly(N-isopropylacrylamide)/carboxymethylchitosan hydrogel for drug controlled release.

Multi-responsive composite microspheres were synthesized via an in situ free radical polymerization of thermo-responsive poly(N-isopropylacrylamide) (poly(NIPAAm)) in the presence of carboxymethylchit...

Magnetic field-responsive release of transforming growth factor beta 1 from heparin-modified alginate ferrogels.

Stimuli-responsive polymeric systems have been widely used for various drug delivery and tissue engineering applications. Magnetic stimulation can be also exploited to regulate the release of pharmace...

One-pot green synthesis of luminescent gold nanoparticles using imidazole derivative of chitosan.

Water soluble luminescent gold nanoparticles with average size 2.3nm were for the first time synthesized by completely green method of Au(III) reduction using chitosan derivative-biocompatible nontoxi...

Novel aqueous chitosan-based dispersions as efficient drug delivery systems for topical use. Rheological, textural and release studies.

The use of a novel cross-linked thiolated chitosan (CTS) was investigated as the main component of aqueous dispersions (at 1% and 3% w/v) for topical drug delivery systems. The nonionic theophiline (T...

Synthesis of novel amphiphilic hyaluronan containing-aromatic fatty acids for fabrication of polymeric micelles.

Novel hydrophobized hyaluronan (HA) derivatives, containing ω-phenylalkanoic acids (ω-PAA, 4-phenylbutyric acid, 6-phenylhexanoic, 8-phenyloctanoic or 11-tolylundecanoic acids) were prepared by este...

The antihyperlipidemic activities of enzymatic and acidic intracellular polysaccharides by Termitomyces albuminosus.

Two polysaccharides, EIPS and AIPS were obtained by the hydrolysis of IPS from Termitomyces albuminosus, and their pharmacological effects on blood lipid profiles metabolism and oxidative stress were ...

Polyethylene glycol-conjugated chondroitin sulfate A derivative nanoparticles for tumor-targeted delivery of anticancer drugs.

Polyethylene glycol (PEG)-decorated chondroitin sulfate A-deoxycholic acid (CSD) nanoparticles (NPs) were fabricated for the selective delivery of doxorubicin (DOX) to ovarian cancer. CSD-PEG was synt...

Treatment of periodontal disease in older adults.

Within the next 40 years the number of older adults worldwide will more than double. This will impact periodontal treatment needs and presents a challenge to health-care providers and governments wor...

News Articles [5757 Associated News Articles listed on BioPortfolio]

HIV woman facing jail after pricking boy with syringe – The Courier

The CourierHIV woman facing jail after pricking boy with syringeThe CourierAn HIV-infected woman is facing jail after sticking a 12-year-old boy with a hypodermic needle filled with her “body fluids...

Woman with HIV ‘jabbed boy with needle filled with her body fluids after he flushed her drugs down toilet’ – The Sun

The SunWoman with HIV 'jabbed boy with needle filled with her body fluids after he flushed her drugs down toilet'The SunA HIV infected woman who stuck a 12-year-old boy with a hypodermic needle filled...

Spotlight Innovation, FSU collaborate to support development of novel therapies for Zika virus infection

Spotlight Innovation Inc. has entered into a Sponsored Research Agreement with Florida State University to support research directed by FSU Prof. Hengli Tang aimed at developing safe and effective dru...

Can-Fite BioPharma reports financial results, provides update on drug development programs

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs being developed to treat inflammatory diseases, cancer and sexual dysfunction, today reported finan...

Top flight index stays in the red as drugs firms come under fire

London's top flight index remained in the red as drugs firms came under fire when US presidential nominee Hillary Clinton took a swipe at the pharmaceutical industry. http://www.belfasttelegraph.c...

EpiPen Users Have Few Options for Generic or Alternate Drugs

The drug epinephrine has been around for decades, but the EpiPen, which is made by Mylan, has become the go-to epinephrine auto injector for many people in the U.S. There are multiple reasons why the ...

Scientists Track Metabolic Pathways to Find Drug Combo for Pancreatic Cancer

NewsCancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments.

Pharma Has History of Price Gouging, Mylan Should Be No Surprise

Click to view a price quote on MYL. Click to research the Drugs industry.

Important advance made with new approach to ‘control’ cancer, not eliminate it

Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment – to dramatically slow and control tumors on a long-term...

Global drugmakers to conduct clinical trials in Ukraine

The Ministry of Health of Ukraine has officially approved the conduct of clinical trials of drugs imported…

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Companies [270 Associated Companies listed on BioPortfolio]

Reset Therapeutics, Inc.

Reset, a discovery-stage biopharma company co-founded by leaders in the field of circadian biology and Bay City Capital, is developing first-in-class approaches to treating diseas...

SciFluor Life Sciences, Inc.

SciFluor Life Sciences is a drug discovery company developing a best-in-class portfolio of partnership-ready therapeutic drugs strategically capitalizing on the transformational p...

Altan Pharma Limited

Altan Pharma Ltd. is a privately held, specialty pharmaceutical company that develops, manufactures and commercialises injectable drugs for the hospital and other provider segm...

Ensemble Therapeutics

EnsemblinsTM are a new class of synthetic macrocycles developed by Ensemble using its proprietary chemistry platforms, including DNA-Programmed ChemistryTM. Macrocyc...

XenoPort

We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

Verseon

Verseon is a technology-based pharmaceutical company that employs its proprietary computational drug discovery platform to develop novel therapeutics for today’s challenging ...

Enable Injections

Founded February 2010 by medical device industry veterans, Cincinnati, OH-based Enable Injections develops and manufactures devices that allow easy, comfortable patient self-admin...

Icagen, Inc.

Icagen, Inc. is a biopharmaceutical company based in Research Triangle Park, North Carolina, focused on the discovery, development and commercialization of novel orally-administered small molecule...

CureDuchenne Ventures LLC

CureDuchenne Ventures LLC collaborates with pharmaceutical and biotechnology companies to facilitate the development of drugs to treat Duchenne muscular dystrophy. CureDuchenne Ve...

XL-protein GmbH

XL-protein is a privately owned biopharmaceutical company based in Freising, Germany, which exploits its proprietary PASylation® technology to develop biologics with extended p...

Clinical Trials [645 Associated Clinical Trials listed on BioPortfolio]

Paeoniflorin Combination of Hepatoprotective Drugs Versus Hepatoprotective Drugs Only for Auto-immune Hepatitis

An open-label,prospective, randomized pilot study to evaluate the efficacy, safety and tolerability of paeoniflorin, for the treatment of autoimmune hepatitis (AIH) with mild necroinflamma...

Evaluation of Changes in Consumption of Drugs and Substances After Incarceration

To improve the management and risk reduction, it is essential to understand the evolution of the consumption of psychoactive substances, medicated or not in detention; it does not have at ...

Evaluation of Aerosolized Drugs Deposition During Mechanical Ventilation

Aerosol delivery through a ventilator is influenced by numerous factors from ventilator-related, circuit-related to device-related factors. Aerosolized drug delivery through a ventilator s...

The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial

For the past 130 years, appendectomy has been the standard treatment for appendicitis. Recent studies from Europe have challenged the notion that surgery is the best option, showing that a...

Perioperative Antiplatelet Therapy in Patients With Drug-eluting Stent Undergoing Noncardiac Surgery

The purpose of this study is to evaluate the safety and effectiveness of perioperative antiplatelet therapy in patients with drug-eluting stent undergoing non-cardiac surgery.

Implementation of PPI Medication PGX Testing

USING GENETIC INFORMATION ABOUT THE INDIVIDUAL TO PICK THE RIGHT DRUG FOR THE RIGHT DISEASE AT THE RIGHT DOSE DEFINES PERSONALIZED MEDICINE. THIS PILOT STUDY SEEKS TO INSTITUTE PHARMACOGEN...

This Study Tests the Effect of BI 655066 on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis

To assess the influence of BI 655066 onkinetics of cytochrome P450 (CYP) probe drugs as a means of predicting drug-drug interactions

Evaluating Newly Approved Drugs for Multidrug-resistant TB

endTB Clinical Trial a Phase III, randomized, controlled, open-label, non-inferiority, multi-country trial evaluating the efficacy and safety of five new, all-oral, shortened regimens for ...

"Drugs in Lactation" Analysis Consortium

Some medications taken by the breastfeeding women are excreted into milk, posing a potential risk of toxicity to the infant. The first line of evidence required for toxicity risk assessmen...

Application of Two Anti-angiogenesis Drugs Combined With Chemotherapy in Advanced Colorectal Cancer Under the Background of Precision Medical

The purpose of this study is to determine whether Endostar pumping into vein with Thalidomide are more effective in the treatment of Advanced Colorectal Cancer (ACRC).

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Medical and Biotech [MESH] Definitions

Drugs used by veterinarians in the treatment of animal diseases. The veterinarian's pharmacological armamentarium is the counterpart of drugs treating human diseases, with dosage and administration adjusted to the size, weight, disease, and idiosyncrasies of the species. In the United States most drugs are subject to federal regulations with special reference to the safety of drugs and residues in edible animal products.

Drugs which have received FDA approval for human testing but have yet to be approved for commercial marketing. This includes drugs used for treatment while they still are undergoing clinical trials (Treatment IND). The main heading includes drugs under investigation in foreign countries.

The use of multiple drugs administered to the same patient, most commonly seen in elderly patients. It includes also the administration of excessive medication. Since in the United States most drugs are dispensed as single-agent formulations, polypharmacy, though using many drugs administered to the same patient, must be differentiated from DRUG COMBINATIONS, single preparations containing two or more drugs as a fixed dose, and from DRUG THERAPY, COMBINATION, two or more drugs administered separately for a combined effect. (From Segen, Dictionary of Modern Medicine, 1992)

Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here.

Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.

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