Advertisement

Topics

Diseasemodifying drugs - Biotech, Pharma and Life Science Channel

21:53 EDT 3rd May 2016 | BioPortfolio

PubMed Articles [4735 Associated PubMed Articles listed on BioPortfolio]

(177)Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment.

Metastatic bone lesion is a common syndrome of many cancer diseases in an advanced state. The major symptom is severe pain, spinal cord compression, and pathological fracture, associated with an obvio...

Pyogenic granuloma in patients treated with selective BRAF inhibitors: another manifestation of paradoxical pathway activation.

Cutaneous toxicities under therapy with selective BRAF inhibitors such as vemurafenib or encorafenib (LGX818) are frequent, including plantar hyperkeratosis, squamous cell carcinoma, and second primar...

Hypertension Is a Key Feature of the Metabolic Syndrome in Subjects Aging with HIV.

With widespread and effective antiretroviral therapy, the life expectancy in the HIV population has dramatically improved over the last two decades. Consequently, as patients are aging with HIV, other...

Sex, Drugs, and the Neurobiology of the Placebo Effect.

Update on Novel Drugs for Primary Care Practice: Drugs Approved by the U.S. Food and Drug Administration in 2015.

Lipid Rescue - Efficacy and Safety Still Unproven.

Intralipid(®) , the soybean oil-based nutritional lipid emulsion for intravenous administration, has maintained a remarkably safe record for more than 50 years. In conventional use, its rare adverse ...

Molecular Basis of the Receptor Interactions of Polysialic Acid (polySia), polySia Mimetics, and Sulfated Polysaccharides.

Polysialic acid (polySia) and polySia glycomimetic molecules support nerve cell regeneration, differentiation, and neuronal plasticity. With a combination of biophysical and biochemical methods, as we...

Recent progress in the development of Toll-like receptor (TLR) antagonists.

Pattern recognition receptors (PRRs) of the innate immune system mediate and control the activation and progression of adaptive immunity. Toll-like receptors (TLRs) are the most notable of the PRRs: t...

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs.

Drug sensitivity and resistance are conventionally quantified by IC50 or Emax values, but these metrics are highly sensitive to the number of divisions taking place over the course of a response assay...

Remote Ischemic Conditioning - Endogenous Tissue Protection and its Possible Applications in Surgery.

Tissue perfusion is pivotal to wound healing and tissue regeneration after surgery. Ischemia and reperfusion lead to inflammatory reactions with consecutive tissue damage and necrosis. Multiple condit...

News Articles [5391 Associated News Articles listed on BioPortfolio]

BioNovus Innovations and the University of Kansas Medical Center's Institute for Advancing Medical Innovation Announce Partnership

KANSAS CITY, Mo., May 3, 2016 /PRNewswire/ -- BioNovus Innovations LLC and the University of Kansas Medical Center's Institute for Advancing Medical Innovation (IAMI) today announced a new partnership...

1 in 3 Antibiotics Prescribed in the U.S. Are Unnecessary, Major Study Finds

(Washington Post) – Nearly a third of antibiotics prescribed in doctors’ offices, emergency rooms and hospital-based clinics in the United States are not needed, according to the most in...

Pfizer revenues surge as vaccines, new drugs rack up sales

The strong performance in the first quarter gives the drug giant some consolation after its $160 billion merger with Allergan was scuttled by new tax rules. 

Got Unused Meds? Here's What to Do

TUESDAY, May 3, 2016 -- While doing your spring cleaning, don't just toss out expired or unused prescription medications. Unwanted drugs need to be properly disposed of to reduce the risk of abuse or ...

For ADHD, Start With Behavior Therapy, Not Drugs: CDC

TUESDAY, May 3, 2016 -- Behavior modification therapy is preferable to drugs for treating children 2 to 5 years old who have attention deficit hyperactivity disorder, U.S. health officials say. "Behav...

Will Biogen's Hemophilia Spinoff Hurt the Company Long Term?

Click to view a price quote on BIIB. Click to research the Drugs industry.

CDC: Preschoolers with ADHD often given drugs before therapy

Too many preschoolers with ADHD still are being put on drugs right away, before behavior therapy is tried, health officials say.

Pfizer boosted by strong Q1 and possible cancer blockbuster

After the bruising encounter with US tax authorities that ended its $160 billion merger with Allergan last month, Pfizer can take some solace from a strong first quarter performance of its new drugs ...

Recap: BIO Stakeholder Briefing on the Medicare Part B Drug Payment Model

On March 8, 2016, the Centers for Medicare and Medicaid Services’ (CMS) Center for Medicare and Medicaid Innovation (CMMI) published a Proposed Rule to test alternative payment models for the reimbu...

FDA Drug Shortages: 05/02/16 Update

NewsThe FDA sent an update on 05/02 of the drugs that are currently in shortage.Staff Author: 

Events [0 Results]

None

Companies [270 Associated Companies listed on BioPortfolio]

Reset Therapeutics, Inc.

Reset, a discovery-stage biopharma company co-founded by leaders in the field of circadian biology and Bay City Capital, is developing first-in-class approaches to treating diseas...

SciFluor Life Sciences, Inc.

SciFluor Life Sciences is a drug discovery company developing a best-in-class portfolio of partnership-ready therapeutic drugs strategically capitalizing on the transformational p...

Altan Pharma Limited

Altan Pharma Ltd. is a privately held, specialty pharmaceutical company that develops, manufactures and commercialises injectable drugs for the hospital and other provider segm...

Ensemble Therapeutics

EnsemblinsTM are a new class of synthetic macrocycles developed by Ensemble using its proprietary chemistry platforms, including DNA-Programmed ChemistryTM. Macrocyc...

XenoPort

We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

Verseon

Verseon is a technology-based pharmaceutical company that employs its proprietary computational drug discovery platform to develop novel therapeutics for today’s challenging ...

Enable Injections

Founded February 2010 by medical device industry veterans, Cincinnati, OH-based Enable Injections develops and manufactures devices that allow easy, comfortable patient self-admin...

Icagen, Inc.

Icagen, Inc. is a biopharmaceutical company based in Research Triangle Park, North Carolina, focused on the discovery, development and commercialization of novel orally-administered small molecule...

CureDuchenne Ventures LLC

CureDuchenne Ventures LLC collaborates with pharmaceutical and biotechnology companies to facilitate the development of drugs to treat Duchenne muscular dystrophy. CureDuchenne Ve...

XL-protein GmbH

XL-protein is a privately owned biopharmaceutical company based in Freising, Germany, which exploits its proprietary PASylation® technology to develop biologics with extended p...

Clinical Trials [509 Associated Clinical Trials listed on BioPortfolio]

Evaluating Newly Approved Drugs for Multidrug-resistant TB

endTB Clinical Trial a Phase III, randomized, controlled, open-label, non-inferiority, multi-country trial evaluating the efficacy and safety of five new, all-oral, shortened regimens for ...

"Drugs in Lactation" Analysis Consortium

Some medications taken by the breastfeeding women are excreted into milk, posing a potential risk of toxicity to the infant. The first line of evidence required for toxicity risk assessmen...

Application of Two Anti-angiogenesis Drugs Combined With Chemotherapy in Advanced Colorectal Cancer Under the Background of Precision Medical

The purpose of this study is to determine whether Endostar pumping into vein with Thalidomide are more effective in the treatment of Advanced Colorectal Cancer (ACRC).

Low-dose Combination of Three Antihypertensive Drugs

The aim of the study is to compare the efficacy and safety of low-dose combination of three antihypertensive drugs versus fixed high-dose combination of two antihypertensive drugs in arter...

Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

The purpose of the study is to learn from the real world practice of prescribing targeted therapies to patients with advanced cancer whose tumor harbors a genomic variant known to be a dru...

Incretin-mimetic Hypoglycemic Drugs and Severe Retinopathy

Experimental data suggest that GLP-1 promote endothelial cell growth and angiogenesis which may have beneficial effects on the cardiovascular system but harmful effects on the retina . Thi...

Peripheral Blood Biomarkers Associated With CIPN

The investigators are doing a research study that will teach us about the tingly pain that people develop when they get chemotherapy.

Triumeq As an Integrase Single Tablet Regimen in People With HIV Who Inject Drugs

The purpose of this study is to assess the tolerability, adherence and efficacy of single tablet dolutegravir/abacavir/lamivudine antiretroviral therapy in people living with HIV with a hi...

Clinical Trial of Tumor Cell-derived Microparticles Packaging Chemotherapeutic Drugs to Treat Malignant Pleural Effusion

The study is to investigate the anticancer effect and the related immunological mechanism of MTX-ATMPs in the treatment of malignant pleural effusion.

EMBRACE-SC: Observational Study of Subcutaneous (SC) Tocilizumab Alone or in Combination With Conventional Disease-Modifying Antirheumatic Drugs (cDMARDs) in Rheumatoid Arthritis

The purpose of this study is to evaluate the percentage of participants treated with subcutaneous (SC) Tocilizumab who are still on treatment after 52 weeks and the factors that play a maj...

Videos

None available.

Medical and Biotech [MESH] Definitions

Drugs used by veterinarians in the treatment of animal diseases. The veterinarian's pharmacological armamentarium is the counterpart of drugs treating human diseases, with dosage and administration adjusted to the size, weight, disease, and idiosyncrasies of the species. In the United States most drugs are subject to federal regulations with special reference to the safety of drugs and residues in edible animal products.

Drugs which have received FDA approval for human testing but have yet to be approved for commercial marketing. This includes drugs used for treatment while they still are undergoing clinical trials (Treatment IND). The main heading includes drugs under investigation in foreign countries.

The use of multiple drugs administered to the same patient, most commonly seen in elderly patients. It includes also the administration of excessive medication. Since in the United States most drugs are dispensed as single-agent formulations, polypharmacy, though using many drugs administered to the same patient, must be differentiated from DRUG COMBINATIONS, single preparations containing two or more drugs as a fixed dose, and from DRUG THERAPY, COMBINATION, two or more drugs administered separately for a combined effect. (From Segen, Dictionary of Modern Medicine, 1992)

Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here.

Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.

Quick Search
Advertisement
 
review and buy Diseasemodifying drugs market research data and corporate reports here

Channels Quicklinks