Fibrin sealant OMRIX - Biotech, Pharma and Life Science Channel
PubMed Articles
BACKGROUND: This study aimed to assess the feasibility of single-access fetal endoscopy (SAFE) for the management of myelomeningocele (MMC) using intrauterine carbon dioxide as a distension medium in...
In cartilage repair, scaffold-assisted one-step approaches are used to improve the microfracture (Mfx) technique. Since the number of progenitors in Mfx is low and may further decrease with age, aim o...
PURPOSE: Fibrin sealant for mesh fixation has significant positive effects on early outcome after laparoscopic ventral hernia repair (LVHR) compared with titanium tacks. Whether fibrin sealant fixatio...
Evidence indicates a critical role for cerebrovascular dysfunction in Alzheimer's disease (AD) pathophysiology. We have shown that fibrin(ogen), the principal blood-clotting protein, is deposited in t...
Aim:A novel hemostatic sealant based on the in situ gel formation of gelatin catalyzed by thrombin and crosslinked by transglutaminase was designed. The aim of this study was to investigate the effica...
Coagulation factor VIII (FVIII) plays an essential role in haemostasis. To date, physiologic activity of FVIII circulating in the bloodstream (S-FVIII) is evaluated by classic coagulation assays. Howe...
The Practitioners Engaged in Applied Research and Learning (PEARL) Network conducted a three-armed randomized clinical study to determine the comparative effectiveness of three treatments for hypersen...
Inflammation and oxidative stress play key roles in atherosclerotic plaque instability, and plaque rupture/erosion and subsequent thrombus formation constitute the principal mechanisms of total vessel...
Fibrinolysis (plasmin-mediated cleavage of fibrin structures) is a process in which fibrin clots can be removed from blood vessels, allowing the return of normal vascular function. Although several me...
Coronary atherothrombotic disease, including chronic stable angina and acute coronary syndromes (ACS), is associated with significant global burden. The acute clinical manifestations of atherothrombot...
News Articles
DuPont Packaging Survey Results: ‘Convenience’ Food Packaging Changed Our Lives
Winners Revealed at 25th DuPont Awards for Packaging Innovation. WILMINGTON, Del. (PRWEB) May 20, 2013 Recloseable packaging and microwaveable plastic trays were named top packaging breakthroughs tha...
Professionals Can Now Achieve PRP Training Through Elite AMBT
Ormond Beach, FL, May 15, 2013 --(PR.com)-- Specialists for cosmetic medical training courses, Elite AMBT have announced a new addition to the line-up of affordable, innovative courses within their s...
PITTSBURGH, May 14, 2013 /PRNewswire/ -- Cohera Medical, Inc.® (www.coheramedical.com), a leading innovator and developer of absorbable surgical adhesives and sealants, announced it has completed...
A DNA-unraveling enzyme in neutrophils is essential for deep vein thrombosis
BOSTON, May 6, 2013 /PRNewswire-USNewswire/ -- It takes more than platelets, thrombin and fibrin to build a deep vein thrombosis (DVT). Increasingly, researchers are recognizing that neutrophils—...
NEW YORK, NY and LONDON -- (Marketwired) -- 04/30/13 -- Celsus Therapeutics (OTCQB: MRRBY), an emerging growth, development-stage biotech company, announced the addition of Pharma/Biotech industry ve...
Cohera treats first patient in clinical study of Sylys Surgical Sealant
Cohera Medical, a developer of absorbable surgical adhesives and sealants, has treated the first patient in a clinical study of its Sylys surgical sealant.
First Patient Treated In Study Of Cohera Medical's Sylys™ Surgical Sealant
PITTSBURGH, April 23, 2013 /PRNewswire/ -- Cohera Medical, Inc.® (www.coheramedical.com), leading innovator and developer of absorbable surgical adhesives and sealants, today announced the t...
Novel Procedure Seals Corneal Perforations
A combination of an autologous fibrin membrane and platelet-rich plasma appears to be safe and effective for treating perforated corneal...
Events
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Companies
Ocular Therapeutix, Inc. is a privately held company based in Bedford, MA, focused on the development and commercialization of ophthalmic therapeutic products using its proprietar...
Clinical Trials
The assessment of patients with suspected deep vein thrombosis (DVT) is a common clinical scenario that, despite major advances in diagnostic testing, continues to be challenging. The dia...
RATIONALE: Fibrin sealant may decrease lymphedema following surgery to remove lymph nodes in the groin by helping to seal the lymphatic vessels. It is not yet known if fibrin sealant is ef...
Postoperative wound disturbances, particularly surgical site infection of the chest and leg incision site following cardiac surgery are associated with increased morbidity, mortality, and...
Evaluating the Use of Fibrin Tissue Adhesive in Melanoma Patients
Primary Objective: 1. To determine whether the use of a fibrin sealant applied to superficial groin soft tissues following node dissection can result in decreased cumulative postoperativ...
Assessment of Fibrin Glue in Pterygium Surgery and Other Forms of External Eye Surgery
Tisseel fibrin adhesive has been used extensively in many forms of surgery. Its use in eye surgery has been relatively recent. A few studies recently showed it was effective in securing co...
Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma
Background Seroma formation is a common problem after mastectomy. The incidence various between 30% to 92%. It is often an ongoing problem after removal of the suction drain, and repeated...
Safety and Efficacy Study of Eptifibatide in Primary Percutaneous Coronary Intervention (PCI)
Rationale: ST-elevation myocardial infarction (STEMI) is usually triggered by rupture of an atherosclerotic plaque that then accumulates platelets and fibrin and leads to an occlusive...
BRAIN (Biomarker Rapid Assessment of Ischemic iNjury)
This project is designed to evaluate the clinical utility of a novel blood test, the Triage Stroke Panel, as an aid in the diagnosis and assessment of stroke. The Triage Stroke Panel test...
Performance and Safety of Bone Substitute MBCP-FS in Maxillary Sinus Lift Procedures
The purpose of this study is to evaluate the performance and to monitor the safety of the bone substitute Macroporous Biphasic Calcium Phosphate-Fibrin Sealant Vapor Heated Solvent/Deterge...
The purpose of this study was to assess whether endoscopic sclerotherapy with Fibrin Sealant was superior to ligature, with or without Polidocanol, in achieving hemostasis in bleeding esop...
Videos
Evicel Partial Nephrectomy
Haemostatic techniques during partial nephrectomy using the daVinci Si at the Royal Liverpool University Hospital.
Medical and Biotech [MESH] Definitions
Fibrin Modulating Agents
Agents that affect the function of FIBRIN in BLOOD COAGULATION. They used as COAGULANTS for HEMORRHAGE or ANTICOAGULANTS for THROMBOSIS.
Antithrombin Proteins
An endogenous family of proteins belonging to the serpin superfamily that neutralizes the action of thrombin. Six naturally occurring antithrombins have been identified and are designated by Roman numerals I to VI. Of these, Antithrombin I (see FIBRIN) and ANTITHROMBIN III appear to be of major importance.
Thrombelastography
Use of a thrombelastograph, which provides a continuous graphic record of the physical shape of a clot during fibrin formation and subsequent lysis.
Thrombin
An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN.
Thrombin Time
Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin.
