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Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

13:25 EST 4th December 2016 | BioPortfolio

PubMed Articles [11528 Associated PubMed Articles listed on BioPortfolio]

Impact of d-limonene synthase up- or down-regulation on sweet orange fruit and juice odor perception.

Citrus fruits are characterized by a complex mixture of volatiles making up their characteristic aromas, being the d-limonene the most abundant one. However, its role on citrus fruit and juice odor is...

Comparison of phytochemical profiles, antioxidant and cellular antioxidant activities of different varieties of blueberry (Vaccinium spp.).

Numerous reports have demonstrated that the consumption of fruits and vegetables is beneficial for the human health. Blueberries, in particular, are rich in phytochemicals including free and bound for...

CYP2D6 and CYP2A6 biotransform dietary tyrosol into hydroxytyrosol.

The dietary phenol tyrosol has been reported to be endogenously transformed into hydroxytyrosol, a potent antioxidant with multiple health benefits. In this work, we evaluated whether tyrosine hydroxy...

Speciation of chromium in bread and breakfast cereals.

Bread and breakfast cereals are a major constituents of the human diet, yet their Cr(VI) content is not known. Chromium(VI) was determined in these products by high resolution continuum source atomic ...

Comparison of gravimetric, creamatocrit and esterified fatty acid methods for determination of total fat content in human milk.

The gravimetric method is considered the gold standard for measuring the fat content of human milk. However, it is labor intensive and requires large volumes of human milk. Other methods, such as crea...

Nutritional value of duckweeds (Lemnaceae) as human food.

Duckweeds have been consumed as human food since long. Species of the duckweed genera, Spirodela, Landoltia, Lemna, Wolffiella and Wolffia were analysed for protein, fat, and starch contents as well a...

Biochemical and Pathophysiological Premises to Positron Emission Tomography With Choline Radiotracers.

Choline is a quaternary ammonium base that represents an essential component of phospholipids and cell membranes. Malignant transformation is associated with an abnormal choline metabolism at a higher...

An Innovative Assay for the Analysis of In Vitro Endothelial Remodeling: Experimental and Computational Evidence.

The molecular and cellular mechanisms underlying vascular remodeling are currently investigated by experimental strategies which aim to mimic the complex environmental conditions found in vivo. Some o...

Syntheses of Human TLR8-Specific Small-Molecule Agonists.

Human toll-like receptor (hTLR)-8 is expressed in myeloid dendritic cells, monocytes, and monocyte-derived dendritic cells. Engagement by TLR8 agonists evokes a distinct cytokine profile which favors ...

Biosynthetic Approaches to Squalene Production: The Case of Yeast.

Squalene is a precursor in the eukaryotic sterol biosynthesis. It is a valuable compound with several human health-related applications. Since the traditional natural resources of squalene are limited...

News Articles [5606 Associated News Articles listed on BioPortfolio]

Global Human Insulin Market USD 32.8 Billion by 2020, Research Study by iHealthcareAnalyst, Inc.

Maryland Heights, MO, December 04, 2016 --(PR.com)-- The global human insulin market is estimated to reach USD 32.8 Billion in 2020, expanding at a CAGR of 4.8% from 2016 to 2020, published by iHealt...

Genetic Literacy Project’s Top 6 Stories for the Week, December 5, 2016

Remissions following anti-CD22 CAR therapy in children with relapsed ALL

Dr Fry presents at ASH 2016 with results from the first-in-human anti-CD22 CAR T-cell therapy. More information is available in news coverage from ecancer here. These results were discussed further ...

Anti CD22 CAR T cell therapy for relapsed paediatric ALL

Dr Shah speaks with ecancertv at ASH 2016 about the first-in-human anti-CD22 CAR T-cell therapy. She describes how therapies targetting CD19 results in diminished expression in many patients, openi...

Human Blood Substitutes, Once Dead, Now Resuscitated

uBiome Awards Microbiome Impact Grant to Explore Effects of Heavy Drinking and Smoking on Oral Microbiome

uBiome, the leader in microbial genomics, awards scientific grant to Dr. Renato Polimanti of the Yale University School of Medicine, who will investigate the impact of heavy smoking and drinking behav...

CRISPR in color: Allen Institute edits genes to create color-coded stem cells

A cluster of human induced pluripotent stem cells contains dyes that highlight cell membranes (purple) and DNA in the nucleus (blue). Spindles from microtubules, shown in white at the center of the im...

Global Autoimmune Disease Diagnostics Market 20172021 Prices from USD $3500

About the Autoimmune Disease Diagnostics Market Abnormal immune responses of the innate immune system can cause autoimmune diseases, which can damage body tissues and lead to abnormal organ functions....

Meds don't cut trastuzumab-tied left ventricular remodeling

(HealthDay)—For patients with human epidermal growth factor receptor 2-overexpressing (HER2-positive) early breast cancer, perindopril and bisoprolol do not prevent trastuzumab-mediated left ventric...

Human Genome Sciences, Inc. Mergers Acquisitions MA, Partnerships Alliances and Investment Report Prices from USD $350

SummaryMarketLine's Company Mergers Acquisitions MA, Partnerships Alliances and Investments reports offer a comprehensive breakdown of the organic and inorganic growth activity undertaken by an orga...

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Companies [316 Associated Companies listed on BioPortfolio]

Eccovia Solutions

Eccovia Solutions is a trusted provider of industry-leading software and services for health and human service organizations. As an innovator in cloud-based technology, we are at ...

Effective Health Systems, LLC

Effective Health Systems (www.effectivehealthsystems.com) was launched in 2007. Effective Health Systems is a human capital management firm whose focus is on delivering technologi...

Biomoda

Biomoda, Inc. is a developmental stage company engaged in the business of developing biopharmaceutical technology to diagnose and treat human diseases. The Company currently licenses two patents in th...

The International WELL Building Institute

The International WELL Building Institute (IWBI) is a for-benefit organization (B-Corp) whose mission is to improve human health and wellbeing through the built environment. IWBI ...

Mawi DNA Technologies

Mawi DNA Technologies was founded in 2013 and has developed and commercialized the iSWAB technology, an innovative system for collection of biosamples. The company’s flags...

Octapharma Group

Headquartered in Lachen, Switzerland, Octapharma is one of the largest human protein manufacturers in the world, developing and producing human proteins from human plasma and huma...

Unite US

Unite US is a technology platform reinventing the delivery of health, employment, and human services. The company is disrupting the fragmented health and human services industry b...

MOLOGEN AG

MOLOGEN is specializing in selected areas of Molecular Medicine. Our areas of competence are gene expression, gene therapy and bioinformatics. We are dedicated to the development of DNA expression and...

SAB Biotherapeutics, Inc.

SAB Biotherapeutics, Inc. (SAB), headquartered in Sioux Falls, S.D. is an established, biopharmaceutical company that is leading the science and manufacturing of immunoglobulin th...

Sandbox

Launched in 2016, Sandbox is an independent, full-service agency formed by four complementary entrepreneurial agencies united by a "play well together" ethos of collaboration. Hea...

Clinical Trials [1958 Associated Clinical Trials listed on BioPortfolio]

Effects of SNP of GnRH Receptor Genes in IVF Patients

Gonadotropin-releasing hormone analogue (GnRH-a) "long protocol" is a protocol for pituitary down-regulation in IVF. However, it is common in clinic that some patients are hypersensitive t...

Milk Biofortification Promotes Health Benefits in Institutionalized Elderly

The project aims to study the effects of inclusion of sunflower oil, vitamin E and selenium in the diet of dairy cows on milk composition and the influence of modified milk on nutrition an...

Phase I/II Study of U3-1402 in Subjects With Human Epidermal Growth Factor Receptor 3 (HER3) Positive Metastatic Breast Cancer

This is an open-label, three-part, non-randomized, multiple-dose study to evaluate safety, tolerability, and efficacy of U3-1402 in patients with HER3-positive metastatic breast cancer. HE...

Effects of Prolonged Roll-tilt in Healthy Human Subjects

The long-term goal of this research is to advance the investigators knowledge of how the brain combines the information of multiple sensory systems coding for spatial oriention and how ada...

Immunogenicity and Safety of a Tetravalent Dengue Vaccine Administered Concomitantly or Sequentially With Cervarix®

The aim of this study is to investigate the immunogenicity and safety of CYD dengue vaccine and Cervarix when administered concomitantly or sequentially in healthy female subjects aged 9-1...

A Randomized Controlled Trial Comparing a Solo and Non-solo Approach for Laparoscopic Cholecystectomy

To determine the safety and feasibility of solo laparoscopic cholecystectomy, which is defined as the application of solo surgery to laparoscopic cholecystectomy, by comparing consecutive ...

First In Human Safety, Pharmacokinetics and Anti-tumoral Activity of GM102 in Gynecological Cancers

First in human study, assessing the safety profile, the pharmacokinetics and preliminary antitumor activity of GM102, a new compound (a monoclonal antibody), administered alone in patients...

The Efficacy of Surgical Treatment in Combinations With Intraperitoneal Immunotherapy (With Interleykin-2 - Human Cytokine Reaction Activator) and Systemic Chemotherapy in Patients With Gastric Cancer and Verified Free Cancer Cells

The purpose of this study is to determine whether intraperitoneal immunotherapy (with interleykin-2 - human cytokine reaction activator) with systemic chemotherapy will be more effective t...

Artificial Shrinkage for Human Blastocyst Prior Vitrification

Investigators aim to investigate the effect of elimination of blastocoelic fluid by creating a large hole in the zona pellucida at the cellular junction of the trophectoderm cells located ...

Fibrinolysis vs Thoracoscopy for Pleural Infection

The purpose of this prospective randomized clinical trial is to compare two currently accepted standard-of-care treatment strategies: Medical thoracoscopy as compared to instillation of in...

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Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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