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Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

05:59 EDT 1st July 2016 | BioPortfolio

PubMed Articles [11291 Associated PubMed Articles listed on BioPortfolio]

Difficulties facing healthcare workers in the era of AIDS treatment in Lesotho.

Sub-Saharan Africa is most affected by the AIDS pandemic and Lesotho is no exception. In many countries, healthcare workers are at the forefront of the fight against AIDS. This study explores the diff...

Pre-clinical evaluation of eight DOTA coupled gastrin-releasing peptide receptor (GRP-R) ligands for in vivo targeting of receptor-expressing tumors.

Overexpression of the gastrin-releasing peptide receptor (GRP-R) has been documented in several human neoplasms such as breast, prostate, and ovarian cancer. There is growing interest in developing ra...

Design and conduct of the activated protein C and corticosteroids for human septic shock (APROCCHSS) trial.

We aimed at assessing the benefit-to-risk ratio of activated protein C (drotrecogin-alfa activated, DAA) and corticosteroids, given alone or in combination, in patients with septic shock.

Modification biological activity of S and R forms of Proteus mirabilis and Burkholderia cepacia lipopolysaccharides by carrageenans.

The modification of biological features of S and R forms of Proteus mirabilis and Burkholderia cepacia LPS by kappa/iota and kappa/beta carrageenans was shown in Limulus activation test, ELISA, human ...

Possible Transmission of mcr-1-Harboring Escherichia coli between Companion Animals and Human.

Mutation in West Nile Virus Structural Protein prM during Human Infection.

A mutation leading to substitution of a key amino acid in the prM protein of West Nile virus (WNV) occurred during persistent infection of an immunocompetent patient. WNV RNA persisted in the patient'...

Improved stability and controlled release of CLA with spray-dried microcapsules of OSA-modified starch and xanthan gum.

The objective of this investigation was to improve the stability of CLA and to allow for its controlled release by encapsulating it with combinations of octenyl-succinic anhydride (OSA) starch and xan...

Three dimensional alginate-fucoidan composite hydrogel augments the chondrogenic differentiation of mesenchymal stromal cells.

Presence of sulfated polysaccharides like heparan sulphate has often been implicated in the regulation of chondrogenesis. However, recently there has been a plethora of interest in the use of non-anim...

Development of chitosan/β-glycerophosphate/glycerol hydrogel as a thermosensitive coupling agent.

This work develops a dual-function thermosensitive hydrogel to prevent overheating, a side effect of focused ultrasound therapy. The proposed hydrogel has the components of chitosan, β-glycerophospha...

Long non-coding RNA H19 can predict a poor prognosis and lymph node metastasis: a meta-analysis in human cancer.

A long non-coding RNA (lncRNA) H19 has been reported to be aberrantly regulated in a wide range of cancers. This meta-analysis was performed to explore the potential value of H19 as a biomarker for ca...

News Articles [5170 Associated News Articles listed on BioPortfolio]

Submerged Pigs Inform Forensics

Watching the decomposition of pig carcasses anchored to the seafloor is helping forensic researchers understand what to expect of human remains dumped in the ocean.

Pharmaceutical Research: Melatonin Delivery: Transdermal and Transbuccal Evaluation in Different Vehicles

Type: Original PaperPurposeMelatonin (MLT) could be candidate drug for treatment of several diseases because of its high antioxidant and anticarcinogenic activity and its important biological roles. T...

CRISPR gene-editing approved for first human trials

Backed by Sean Parker, researchers aim to reprogram T cells to fight cancer. SOURCE June, 2016 A federal ethics and biosafety panel has approved the first ever human trials of the CRISPR-Cas9 gene edi...

How boxes of infant skulls helped solve a 19th-century medical mystery

A new paper reveals the story behind 54 infant and fetal skulls dissected by medical scholars centuries ago, yielding important insights into human anatomy.

U.S. Needs Greater Preparation for Next Severe Public Health Threats, Panel Finds

In a report released today by the U.S. Department of Health and Human Services (HHS), an Independent Panel formed to review HHS's response to Ebola made several recommendations on how the nation's fed...

The impact of hypertension on leukocyte telomere length: a systematic review and meta-analysis of human studies

Jennifer Currao Joins ArroHealth

HAUPPAGUE, N.Y., June 30, 2016 /PRNewswire/ -- ArroHealth, a full-service provider of risk adjustment and HEDIS services, today announced it has hired Jennifer Currao as Chief Human Resources Off...

Survey of 15,000 women and men reveals scale of infertility

One in eight women and one in ten men have experienced infertility, yet nearly half of them have not sought medical help, according to a study of more than 15,000 women and men in Britain published in...

Cardinal Health Appoints Pamela O. Kimmet Chief Human Resources Officer

DUBLIN, Ohio, June 30, 2016 /PRNewswire/ -- Cardinal Health, a global healthcare services and products company, today announced the appointment of Pamela O. Kimmet as Chief Human Resources Officer, ef...

Stem Cell Treatment for ALS May be Safe

NewsA phase II clinical trial in people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, suggests that transplanting human stem cells into the spinal cord may be done safely.

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Companies [316 Associated Companies listed on BioPortfolio]

Eccovia Solutions

Eccovia Solutions is a trusted provider of industry-leading software and services for health and human service organizations. As an innovator in cloud-based technology, we are at ...

Effective Health Systems, LLC

Effective Health Systems (www.effectivehealthsystems.com) was launched in 2007. Effective Health Systems is a human capital management firm whose focus is on delivering technologi...

Biomoda

Biomoda, Inc. is a developmental stage company engaged in the business of developing biopharmaceutical technology to diagnose and treat human diseases. The Company currently licenses two patents in th...

The International WELL Building Institute

The International WELL Building Institute (IWBI) is a for-benefit organization (B-Corp) whose mission is to improve human health and wellbeing through the built environment. IWBI ...

Mawi DNA Technologies

Mawi DNA Technologies was founded in 2013 and has developed and commercialized the iSWAB technology, an innovative system for collection of biosamples. The company’s flags...

Octapharma Group

Headquartered in Lachen, Switzerland, Octapharma is one of the largest human protein manufacturers in the world, developing and producing human proteins from human plasma and huma...

Unite US

Unite US is a technology platform reinventing the delivery of health, employment, and human services. The company is disrupting the fragmented health and human services industry b...

MOLOGEN AG

MOLOGEN is specializing in selected areas of Molecular Medicine. Our areas of competence are gene expression, gene therapy and bioinformatics. We are dedicated to the development of DNA expression and...

SAB Biotherapeutics, Inc.

SAB Biotherapeutics, Inc. (SAB), headquartered in Sioux Falls, S.D. is an established, biopharmaceutical company that is leading the science and manufacturing of immunoglobulin th...

Sandbox

Launched in 2016, Sandbox is an independent, full-service agency formed by four complementary entrepreneurial agencies united by a "play well together" ethos of collaboration. Hea...

Clinical Trials [1787 Associated Clinical Trials listed on BioPortfolio]

A First-in-Human Study of the Safety of Single Continuous Intravenous (IV) Infusions of CXL-1427 for up to 48 Hours in Healthy Volunteers

This study is designed to assess a safe dosage of the drug CXL-1427 (BMS-986231) in healthy volunteers.

Effects of Hypoxia and Inflammation on Citrulline Synthesis by Ornithine Transcarbamylase in Human Enterocytes

This study aims at exploring the effects of hypoxia and inflammation on the production of citrulline by ornithine transcarbamylase (OTC) activity in enterocytes from explant cultures of du...

Studies of Neuregulin/ERBB Signaling in Human Heart

This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.

Designing a Programming Language for Patient-Oriented Prescriptions

The purpose of this study is to create a human-readable and executable computer language to implement medical prescriptions and to evaluate and refine this language, with the goal of impro...

Soy Modulation of Immune Activation, LDL- Levels, and Lowering Inflammation by Pretzel Isoflavone Dietary Intervention

Combination antiretroviral therapy (ART, HIV medications) dramatically increases the expected lifespan of HIV (Human Immunodeficiency Virus)infected patients; yet, the risks for cardiovasc...

Shigella Sonnei 53G Challenge

Development of an S. sonnei human challenge model using a newly manufactured lyophilized lot of S. sonnei strain 53G (Lot 1794) that can be used in the future as a challenge strain for all...

Clinical Trial Study About Human Adipose-Derived Stem Cells in the Stroke

The objective of the study is to confirm the safety and possible efficacy of Adipose-Tissue Derived Stem Cells treatment of chronic stroke. Specifically, the study will transplant autologo...

Alisertib and TAK-228 in Participants With Human Papilloma Virus (HPV) Associated Malignancies

The goal of this clinical research study is to find the highest tolerable dose of the combination of alisertib and TAK-228 that can be given to participants with advanced solid tumors that...

Intervention to Encourage HIV Testing and Counseling Among Adolescents

This study aims to minimize risk of human immunodeficiency virus (HIV) in adolescent boys and girls, ages 15-16, by promoting HIV testing and counseling (HTC) through the use of an interac...

Recruiting African American Fathers/ Sons

The purpose of this study is to develop and pilot test recruitment methods for a future study of prevention of sexually transmitted infections (STI), including the human immunodeficiency v...

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Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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