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Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

22:34 EDT 26th July 2017 | BioPortfolio

PubMed Articles [12147 Associated PubMed Articles listed on BioPortfolio]

Autofluorescence imaging for improved visualization of joint structures during arthroscopic surgery.

The purpose of our study is to develop the arthroscopic autofluorescence imaging (AFI) system to improve the visualization during arthroscopic surgery by real-time enhancing the contrast between joint...

Assessment of gray and white matter structural alterations in migraineurs without aura.

Migraine constitute a disorder characterized by recurrent headaches, and have a high prevalence, a high socio-economic burden and severe effects on quality of life. Our previous fMRI study demonstrate...

Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors.

Melanogenesis is a process to synthesize melanin, which is a primary responsible for the pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and chemical reactions are invo...

Carbonic anhydrase inhibitory properties of some uracil derivatives.

Inhibitors of carbonic anhydrase (CA) have been carried out in many therapeutic applications, especially antiglaucoma activity. In this study, we investigated some uracil derivatives (4-12) to inhibit...

Priming increases the anti-tumor effect and therapeutic window of (177)Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1.

(177)Lu-[DOTA(0), Tyr(3)]-octreotate ((177)Lu-octreotate) is used for treatment of patients with somatostatin receptor (SSTR) expressing neuroendocrine tumors. However, complete tumor remission is rar...

Minimum lesion detectability as a measure of PET system performance.

A phantom in combination with an imaging protocol was developed to measure the limit of small lesion detection on different PET systems. Seven small spheres with inner diameters ranging from 3.95 up t...

Natural extracellular nanovesicles and photodynamic molecules: is there a future for drug delivery?

Photodynamic molecules represent an alternative approach for cancer therapy for their property (i) to be photo-reactive; (ii) to be not-toxic for target cells in absence of light; (iii) to accumulate ...

Advance of autophagy in chronic kidney diseases.

Autophagy, a highly conserved mechanism for cell survival, emerges as an important pathway in many biological processes and diseases conditions. Studies of cultured renal cells, human kidney tissues a...

N-Butyl-2-cyanoacrylate-based injectable and in situ-forming implants for efficient intratumoral chemotherapy.

The local delivery of chemotherapeutic drugs to tumor sites is an effective approach for achieving therapeutic drug concentrations in solid tumors. Injectable implants with the ability to form in situ...

Trace elements in raw milk of buffaloes (Bubalus bubalis) from Campania, Italy.

The profile of 18 trace elements was traced in 68 milk samples collected from buffalo farms in the territory known as the "Land of Fires" in the Campania region (Italy). This area has been polluted by...

News Articles [5072 Associated News Articles listed on BioPortfolio]

The antibiotic course has had its day

Antibiotics are vital to modern medicine and antibiotic resistance is a global, urgent threat to human health. The relation between antibiotic exposure and antibiotic resistance is unambiguous both......

Using CRISPR, scientists efficiently edit genome of viable human embryos

Some of the nation's leading scientists have long warned against such work, which was carried out by researchers at Oregon Health & Science University.

First Human Embryos Edited in U.S.

Researchers have demonstrated they can efficiently improve the DNA of human embryos.

Male Hypogonadism Market by Therapy Testosterone Replacement therapy and Gonadotropin and GonadotropinReleasing Hormones Therapy Luteinizing Hormone LH, FollicleStimulating Hormone FSH, Human Chorionic Gonadotropin hCG, and GonadotropinReleasing Hormone G

Male hypogonadism is a medical condition characterized by the inability of the testes to produce sufficient amount of testosterone, which is responsible for the development of secondary sexual charact...

Civitas Solutions, Inc. to Present at Canaccord Genuity Growth Conference in August

Civitas Solutions, Inc. (NYSE: CIVI) today announced that its management will present at the Canaccord Genuity 2017 Growth Conference in Boston. Civitas Solutions’ presentation ...

GSK Trims Nutritional Drink Lines, Wants All Of Its Consumer JV Pie

With its July 26 earnings report, the UK firm made clear it's ready to become sole owner of its consumer...    

Accounting for human immune diversity increases clinical relevance of fundamental immunological research

Mouse models have advanced our understanding of immune function and disease in many ways but they have failed to account for the natural diversity in human immune responses. As a result, insights gain...

Western sperm counts 'halved' in last 40 years

"Sperm counts among Western men have halved in last 40 years," The Guardian reports. A major review of research carried out since 1973 found an estimated 50-60% drop in sperm count in develo...

Human medicines European public assessment report (EPAR): Sevelamer carbonate Zentiva, sevelamer carbonate, Revision: 7, Authorised

Human medicines European public assessment report (EPAR): Renvela, sevelamer carbonate, Revision: 12, Authorised

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Companies [325 Associated Companies listed on BioPortfolio]

Tissue Regenix

Tissue Regenix is a leading medical devices company in the field of regenerative medicine. The company's patented decellularisation ('dCELL®') Technology removes DNA and other ...

Eureka Therapeutics Inc.

Eureka Therapeutics Inc. is a privately held biotechnology company, headquartered in the San Francisco Bay area, focused on developing first-in-class T cell immunotherapies for he...

Alucent Medical, Inc.

Alucent Medical, Inc. is a privately held biotechnology company headquartered in Salt Lake City, Utah. Alucent Medical was founded by Avera Health to develop and market Natural Va...

Chan Zuckerberg Biohub

The CZ Biohub is an independent non-profit medical research organization collaborating with the University of California, Berkeley, Stanford University and the University of Calif...

Tiziana Life Sciences plc

Tiziana Life Sciences plc is a UK biotechnology company that focuses on the discovery and development of novel molecules that treat human disease in oncology and immunology. The C...

Cellular Dynamics International (CDI), a FUJIFILM company

Cellular Dynamics International (CDI), a FUJIFILM company, is a leading developer and supplier of human cells used in drug discovery, toxicity testing, and regenerative medicine a...

Immunomic Therapeutics, Inc.

Immunomic Therapeutics, Inc. (ITI) is a privately-held clinical stage biotechnology company headquartered in Hershey, PA with lab facilities in Rockville, MD. ITI is developing ne...

Evans Incorporated

Evans Incorporated is an award winning, industry leading Consulting and Solutions provider specializing in Human-Centered Solutions in Healthcare, Aviation and International Devel...

KARL STORZ GmbH & Co. KG

Karl Storz began producing instruments for ENT specialists in 1945. His intention was to develop instruments which would enable the practitioner to look inside the human body. The technology available...

TenEleven Group

The TenEleven Group is a software and services company based in Buffalo, NY that provides software solutions for health and human services agencies. Thousands of users in hundreds...

Clinical Trials [2188 Associated Clinical Trials listed on BioPortfolio]

Treating Inflammation in Polycystic Ovary Syndrome to Ameliorate Ovarian Dysfunction

Polycystic Ovary Syndrome (PCOS) is characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovaries. Insulin resistance (IR) is a common feature of PCOS, and the resultant ...

Alterations of Muscle Secretome Associated With Muscle Atrophy Caused by Glucocorticoids

Several studies have shown that lean mass, in particular muscle mass, is an excellent predictive survival factor in many diseases. A better knowledge of the mechanisms responsible for musc...

A Study to Evaluate the Efficacy and Safety of (D/C/F/TAF) Once Daily Fixed Dose Combination (FDC) Regimen in Newly Diagnosed, Antiretroviral Treatment-naive Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants Receiving Care in a Test and Tr

The purpose of this study is to assess the efficacy of Darunavir/ Cobicistat/ Emtricitabine/ Tenofovir Alafenamide (D/C/F/TAF) fixed-dose combination (FDC) in a Test and Treat model of car...

MicroRNAs as Diagnostic Biomarkers in Hepatocellular Carcinoma Among Somali Patients

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and is the third leading cause of cancer that related death in the worldwide. Although, current most of doctors and l...

Study of Targeted Therapy Using Transcription Activator-like Effector Nucleases in Cervical Precancerous Lesions

This is an open-label and triple cohort study of the safety and efficacy of T27 and T512 to possibly treat cervical intraepithelial neoplasia(CIN).

Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients

This is a double-blind, randomized-withdrawal, placebo-controlled study in kidney transplant patients with AMR to evaluate the efficacy and safety of human plasma-derived C1-esterase inhib...

A Study of Recombinant Human Growth Hormone Injection(JINTOPIN AQ)for Short Children With Small for SGA

To preliminary assess the efficacy and safety of recombinant human growth hormone injection on the treatment of small for gestational age (SGA), and determine the best dose.

A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Treatment-Naïve and Treatment-Experienced, Non-Cirrhotic Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With or Without Human Immunodeficiency Virus Co-Infect

A Phase 3, double-blind (DB), placebo-controlled study to evaluate the efficacy and safety of ABT-493/ABT-530 in non-cirrhotic chronic hepatitis C virus (HCV) genotype (GT)1 to GT6-infecte...

Relationship Between Gut Microbiota And Anemia In Chronic Kidney Disease (CKD) Patients

The human intestinal tract harbours a diverse and complex microbial community which plays a central role in human health. It has been estimated that our gut contains in the range of 1000 b...

Impact of Hepatitis C Therapy and Bone Health

An evaluation of the impact of Elbasvir and Grazoprevir (EBR/GZR) HCV therapy on the heart risk and bone health of HCV mono-infected and HIV/HCV co-infected patients.

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Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

Methods of detecting pregnancy by examining the levels of human chorionic gonadotropin (HCG) in plasma or urine.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

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