Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

17:48 EDT 18th September 2014 | BioPortfolio

PubMed Articles [9984 Associated PubMed Articles listed on BioPortfolio]

Preventing and controlling zoonotic tuberculosis: a One Health approach.

The expression One Health refers to the unified human and veterinary approach to zoonoses, an approach that used to be identified with Medicine throughout the 20th Century. Zoonotic tuberculosis (TB),...

Progenitor "Mycobacterium canettii" Clone Responsible for Lymph Node Tuberculosis Epidemic, Djibouti.

"Mycobacterium canettii," an opportunistic human pathogen living in an unknown environmental reservoir, is the progenitor species from which Mycobacterium tuberculosis emerged. Since its discovery in ...

Cardiovascular disease associated with the human immunodeficiency virus: an update.

With the advent of increasingly available antiretroviral therapy (ART), the life expectancy of HIV-infected persons is increasing. As they age, HIV-infected persons have increased propensity to typica...

Profile of Nucleosides and Nucleotides in Donkey's Milk.

Nucleotides play a crucial role to cellular functions; they can be obtained from the diet or through the nucleotide salvage pathway, however, in particular situations (occurring mainly in newborns) th...

Synthesis and Antiretroviral Activity of Novel 4'-Fluoro-5'-Deoxyphosphonic Acid Carbocyclic Nucleoside Analogs.

Novel 5'-deoxycarbocyclic purine phosphonic acid analogs with the 4'-electropositive moiety, fluorine were designed, and synthesized from glyceraldehyde. The cyclopentenol intermediate, 9, was success...

Qualitative screening of 116 veterinary drugs in feed by liquid chromatography-high resolution mass spectrometry: Potential application to quantitative analysis.

Veterinarian and human pharmaceuticals may be intentionally added to animal feed to enhance animal production. Monitoring these substances is necessary for protecting the consumers. In this work, a sc...

Specific tumor labeling enhanced by polyethylene glycol linkage of near infrared dyes conjugated to a chimeric anti-carcinoembryonic antigen antibody in a nude mouse model of human pancreatic cancer.

ABSTRACT. Labeling of metastatic tumors can aid in their staging and resection of cancer. Near infrared (NIR) dyes have been used in the clinic for tumor labeling. However, there can be a nonspecific ...

Assessment of the risk of salmonellosis from internally contaminated shell eggs following initial storage at 18 °C (65 °F), compared with 7 °C (45 °F).

In the U.S., chicken-breeder farms that supply hatcheries typically store and transport eggs intended for broiler production at a temperature of 18.3 °C (65 °F). However, in case of surplus, some ...

Infectious Diseases and Tropical Disease Pathology: SY16-2B PEDIATRIC CEREBRAL MALARIA PATHOLOGY.

Malaria kills more than half a million children a year in sub-Saharan Africa despite the availability of effective combination drug therapy, efficacy of bed nets, and environmental control measures. C...

Biotinidase deficiency and vascular ring malformation: case report.

Biotinidase deficiency is an autosomal recessive metabolic disorder that affects the cleavage of biotin. Family studies of the index case found that both parents are usually carriers and siblings have...

News Articles [5216 Associated News Articles listed on BioPortfolio]

FRC Joins Capitol Hill News Conference in Urging HHS, Congress to Act Following GAO Report on Taxpayer Funding of Abortion

WASHINGTON, Sept. 18, 2014 /PRNewswire-USNewswire/ -- Today, Arina Grossu, Family Research Council's Director of the Center for Human Dignity spoke at a news conference in support of the "No Taxpayer ...

Tumour suppressors: Notch blocks bladder tumorigenesis

Rampias et al. show that Notch signalling is frequently inactivated in human bladder cancers and its loss can promote tumorigenesis in mice through suppressing transcription of phosphatases that norma...

Animal behaviour: The evolutionary roots of lethal conflict

A comprehensive analysis of lethal coalitionary aggression in chimpanzees convincingly demonstrates that such aggression is an adaptive behaviour, not one that has emerged in response to human impacts...

Lethal aggression in Pan is better explained by adaptive strategies than human impacts

Observations of chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) provide valuable comparative data for understanding the significance of conspecific killing. Two kinds of hypothesis have been ...

Climate models: sunk by humans?

Paul Palmer and Matthew Smith's argument that human adaptation to climate change should be incorporated into climate-projection models is entirely reasonable (Nature512, 365–366;10.1038/512365a2014)...

Microbiology: Vaginal microbe makes drug

A bacterium that lives in the human vagina produces an antibiotic, suggesting how the microbiome could be mined for possible drug candidates.Michael Fischbach at the University of California, San Fran...

Genomic Profiling of Human Leishmania braziliensis Lesions Identifies Transcriptional Modules Associated with Cutaneous Immunopathology

POF1B Localizes to Desmosomes and Regulates Cell Adhesion in Human Intestinal and Keratinocyte Cell Lines

Fortune 500 employees can expect to pay more for health insurance, survey says

Employees working for Fortune 500 companies can expect to pay higher employee contributions for their health insurance, according to a survey of chief human resource officers about the impact of the P...

Providence Service to acquire CCHN Group Holdings

The Providence Service Corporation, a leader in the management and provision of human social services, innovative global employment services and non-emergency transportation through a variety of gover...

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Companies [240 Associated Companies listed on BioPortfolio]

Civitas Solutions, Inc.

Civitas Solutions, Inc., which markets its services nationally as The MENTOR Network, is the leading national provider of home- and community-based health and human services to mu...

BioTime, Inc. and Abcodia Ltd.

BioTime is a biotechnology company engaged in research and product development in the field of regenerative medicine. Regenerative medicine refers to therapies based on stem cell ...

NABsys, Inc.

NABsys is a life sciences company working at the intersection of physics, biology, and computer science to develop its proprietary electronic, solid-state DNA sequencing platform. NABsys is one of fiv...

i-Human Patients, Inc.

i-Human Patients, Inc. develops virtual medical training products and services, including its flagship i-Human Patients® platform, launched in November 2012, which educators at...

Flex Pharma, Inc.

Flex Pharma, Inc. is a biopharmaceutical company dedicated to creating innovative, novel treatments for neuromuscular disorders. Flex Pharma has demonstrated initial human effi...

New Leaf Africa

New Leaf Africa is a collaboration of leaders in technology, population health and renewable energy who have joined together to bring sustainable development solutions to A...

Agenus, Inc.

Agenus is an immuno-oncology company developing a portfolio of checkpoint modulators (CPMs), heat shock protein vaccines and adjuvants. Agenus’ checkpoint modulator programs ...

CRISPR Therapeutics

CRISPR Therapeutics is a biopharmaceutical company created to translate CRISPR-Cas9, a breakthrough gene-editing technology, into transformative medicines for serious human geneti...

TransTech Pharma, LLC

TransTech Pharma is a privately held, company focused on the discovery, development, and commercialization of human therapeutics to fill unmet medical needs. The Company’s hi...

Contextual Genomics

Contextual Genomics believes that DNA analysis significantly improves human health and that geography should not be a barrier to the benefits of using molecular information to gui...

Clinical Trials [1271 Associated Clinical Trials listed on BioPortfolio]

Exploratory Study of Natural Killer Cells in Human Skin

Natural Killer (NK) cells play a unique role during innate immune responses as they are able to recognize and eliminate, without specific sensitization, tumors, microbe-infected cells as w...

The Cancer of the Pancreas Screening-5 CAPS5)Study

Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Principal Investigator at each site will be responsible for internal...

Abuse Liability and Human Pharmacology of Mephedrone

The purposes of this study are 1) to evaluate the abuse liability and human pharmacology of mephedrone after oral administration and 2) to compare the pharmacological effects of mephedrone...

Phase II Pharmacokinetics Study of Humalog and Humulin-R With and Without rHuPH20 in Type 1 Diabetes Mellitus

Humalog and Humulin-R (recombinant human insulin) are Food and Drug Administration (FDA) approved medications for the treatment of diabetes mellitus. Recombinant human hyaluronidase PH20 (...

An Open Label Pharmacokinetic, Safety And Efficacy Study Of Maraviroc In Combination With Background Therapy For The Treatment Of HIV-1 Infected, CCR5 -Tropic Children

The primary purpose of this study is to determine the pharmacokinetic properties (what the body does to maraviroc) and to determine a suitable dosing schedule of maraviroc in HIV-1 infecte...

The Effect of Subcutaneous Infusions of 3 Doses of DG3173 on Growth Hormone Levels in Untreated Acromegalics

This study is designed to assess the effect of the different continuous s.c. infusion treatments on the human growth hormone (hGH) levels in untreated acromegalic patients in comparison to...

ICI-VPH: Impact of HPV Immunisation Schedules Against HPV

This randomised clinical trial aims to determine whether an immunization schedule comprising two doses of Gardasil administered six months apart is non-inferior to a schedule comprising th...

Transplantation of Human Embryonic Stem Cell-derived Progenitors in Severe Heart Failure

The purpose of the study is to assess the feasibility and safety of a transplantation of cardiac-committed progenitor cells derived from human embryonic stem cells in patients with severe ...

Digestibility of Selected Resistant Starches in Humans

Dietary fiber is a type of carbohydrate which is not digested in the human small intestine. Whole grains are a source of dietary fiber that are used to promote health; however, using whole...

Stool Composition and Stool Characteristics in Healthy Term Infants Fed Human Milk or Infant Formulas

The primary efficacy objective was to determine and compare stool composition (stool soap and non-soap fatty acids, total fatty acids, minerals, and other stool constituents) among the fee...

Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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