Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

06:21 EDT 29th August 2014 | BioPortfolio

PubMed Articles [9980 Associated PubMed Articles listed on BioPortfolio]

Preventing and controlling zoonotic tuberculosis: a One Health approach.

The expression One Health refers to the unified human and veterinary approach to zoonoses, an approach that used to be identified with Medicine throughout the 20th Century. Zoonotic tuberculosis (TB),...

Progenitor "Mycobacterium canettii" Clone Responsible for Lymph Node Tuberculosis Epidemic, Djibouti.

"Mycobacterium canettii," an opportunistic human pathogen living in an unknown environmental reservoir, is the progenitor species from which Mycobacterium tuberculosis emerged. Since its discovery in...

Qualitative screening of 116 veterinary drugs in feed by liquid chromatography-high resolution mass spectrometry: Potential application to quantitative analysis.

Veterinarian and human pharmaceuticals may be intentionally added to animal feed to enhance animal production. Monitoring these substances is necessary for protecting the consumers. In this work, a sc...

Specific tumor labeling enhanced by polyethylene glycol linkage of near infrared dyes conjugated to a chimeric anti-carcinoembryonic antigen antibody in a nude mouse model of human pancreatic cancer.

ABSTRACT. Labeling of metastatic tumors can aid in their staging and resection of cancer. Near infrared (NIR) dyes have been used in the clinic for tumor labeling. However, there can be a nonspecific...

Assessment of the risk of salmonellosis from internally contaminated shell eggs following initial storage at 18 °C (65 °F), compared with 7 °C (45 °F).

In the U.S., chicken-breeder farms that supply hatcheries typically store and transport eggs intended for broiler production at a temperature of 18.3 °C (65 °F). However, in case of surplus, some...

A comparison of the thermal inactivation kinetics of human norovirus surrogates and hepatitis A virus in buffered cell culture medium.

Human noroviruses and hepatitis A virus (HAV) are considered as epidemiologically significant causes of foodborne disease. Therefore, studies are needed to bridge existing data gaps and determine appr...

Multilocus sequence typing analysis and antibiotic resistance of Clostridium difficile strains isolated from retail meat and humans in Belgium.

Clostridium difficile has been isolated from food animals and meat, specially ground pork and ground beef. The recovered isolates were closely related to C. difficile human strains, indicating that a...

Candida milleri species reveals intraspecific genetic and metabolic polymorphisms.

Candida milleri, together with Candida humilis, is the most representative yeast species found in type I sourdough ecosystems. In this work, comparison of the ITS region and the D1/D2 domain of 26S rD...

Autoimmune Activation toward Embryo Implantation is Rare in Immune-Privileged Human Endometrium.

Human embryo implantation represents embryo apposition, adhesion to the endometrial epithelium, and invasion into the stromal extracellular matrix within 1 to 2 days during days 6 to 9 after ovulation...

How Cells of the Immune System Prepare the Endometrium for Implantation.

Characterized by its cyclical regeneration and differentiation, the endometrium is one of the most dynamic tissues of the human body. As a main player during implantation and later development of the...

News Articles [5230 Associated News Articles listed on BioPortfolio]

The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End

Now approaching the one-year mark since its founding, The Adult Stem Cell Technology Center, LLC (ASCTC) in Boston, Massachusetts has lined-up participation in three conferences focused on stem cells...

The Adult Stem Cell Technology Center, LLC Declines ALS Ice Bucket Challenge Donors Wishing to Support Ethical Research for New Stem Cell Therapies

For more than a week, Boston’s Adult Stem Cell Technology Center, LLC has been declining offers from participants in the Amyotrophic Lateral Sclerosis (ALS) Ice Bucket Challenge who wish to make don...

KRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition

Vaccine for Chagas disease expected to be available within the next three years

The medical development has been tested in animal models, where it was observed that the disease stopped in 80 percent of cases; physicians expect similar results from a human control group.

NIH to start initial human testing of investigational Ebola vaccine next week

Initial human testing of an investigational vaccine to prevent Ebola virus disease will begin next week by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of...

New Research Method Opens Door to Therapy with Human Muscle Stem Cells

Stem cells are essential for the repair of muscle damage, but all attempts to manipulate human muscle stem cells for therapy have thus far failed. Now Dr. Andreas Marg and Prof. Simone Spuler of the...

Human tests of GSK Ebola vaccine to start soon in UK

Human tests of GSK Ebola vaccine to start soon in UK

Chinese Hospital Accused of Stealing Patient’s Organ after Woman Goes in for Minor Surgery and Wakes Up to Find Her Kidney Has Been Removed

(Daily Mail) – A Chinese hospital is being investigated for human organ trafficking after a patient claimed they stole one of her kidneys. Factory worker Wai Jianmin, 29, was admitted to Shenzhe...

The universal 'anger face'

The next time you get really mad, take a look in the mirror. See the lowered brow, the thinned lips and the flared nostrils? That's what social scientists call the "anger face," and it appears to be p...

J&J's Hera Therapeutics Presents Antiviral Drug For HPV

Scientists from Hera Therapeutics, part of the Janssen Labs under the Johnson & Johnson’s external R&D engine, presented results suggesting that its small molecule HTI-1968 has potential...

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Companies [238 Associated Companies listed on BioPortfolio]

i-Human Patients, Inc.

i-Human Patients, Inc. develops virtual medical training products and services, including its flagship i-Human Patients® platform, launched in November 2012, which educators at...

Flex Pharma, Inc.

Flex Pharma, Inc. is a biopharmaceutical company dedicated to creating innovative, novel treatments for neuromuscular disorders. Flex Pharma has demonstrated initial human effi...

New Leaf Africa

New Leaf Africa is a collaboration of leaders in technology, population health and renewable energy who have joined together to bring sustainable development solutions to A...

Agenus, Inc.

Agenus is an immuno-oncology company developing a portfolio of checkpoint modulators (CPMs), heat shock protein vaccines and adjuvants. Agenus’ checkpoint modulator programs...

CRISPR Therapeutics

CRISPR Therapeutics is a biopharmaceutical company created to translate CRISPR-Cas9, a breakthrough gene-editing technology, into transformative medicines for serious human geneti...

TransTech Pharma, LLC

TransTech Pharma is a privately held, company focused on the discovery, development, and commercialization of human therapeutics to fill unmet medical needs. The Company’s hi...

Contextual Genomics

Contextual Genomics believes that DNA analysis significantly improves human health and that geography should not be a barrier to the benefits of using molecular information to gui...

Chelsea Therapeutics International, Ltd.

Chelsea Therapeutics (Nasdaq:CHTP) is a biopharmaceutical development company that acquires, develops and commercializes innovative products for the treatment of a variety of huma...

Isarna Therapeutics GmbH

Isarna Therapeutics has an unmatched commitment to developing TGF-β inhibitors that stimulate the human immune system to effectively fight cancer. Isarna Therapeutics are advancing a unique pip...

Adenovir Pharma AB

Adenovir Pharma AB is a development company developing new solutions for treatment of infectious diseases affecting the eyes. Adenovir Pharma was founded by researchers at the department of Virolo...

Clinical Trials [1271 Associated Clinical Trials listed on BioPortfolio]

An Open Label Pharmacokinetic, Safety And Efficacy Study Of Maraviroc In Combination With Background Therapy For The Treatment Of HIV-1 Infected, CCR5 -Tropic Children

The primary purpose of this study is to determine the pharmacokinetic properties (what the body does to maraviroc) and to determine a suitable dosing schedule of maraviroc in HIV-1 infecte...

ICI-VPH: Impact of HPV Immunisation Schedules Against HPV

This randomised clinical trial aims to determine whether an immunization schedule comprising two doses of Gardasil administered six months apart is non-inferior to a schedule comprising th...

Transplantation of Human Embryonic Stem Cell-derived Progenitors in Severe Heart Failure

The purpose of the study is to assess the feasibility and safety of a transplantation of cardiac-committed progenitor cells derived from human embryonic stem cells in patients with severe...

Digestibility of Selected Resistant Starches in Humans

Dietary fiber is a type of carbohydrate which is not digested in the human small intestine. Whole grains are a source of dietary fiber that are used to promote health; however, using whole...

Stool Composition and Stool Characteristics in Healthy Term Infants Fed Human Milk or Infant Formulas

The primary efficacy objective was to determine and compare stool composition (stool soap and non-soap fatty acids, total fatty acids, minerals, and other stool constituents) among the fee...

Bioequivalence Study of Lisinopril and Hydrochlorothiazide Tablets (20+25) mg Under Fasting Conditions

This is a randomized, open Label, balanced, two-treatment, two-period, two-sequence, single dose, cross over pivotal study. The purpose of this study is to assess the bioequivalence betwee...

Identification the Expression of Sox2 in Colorectal Cancer Tissues

Sox2 has been studied in several types of human solid tumors. The investigators found that Sox2 had higher expression level in colorectal cancer and metastatic tissues than normal tissues....

Real Time Optical Coherence Tomography (OCT) of Human Tissue

This is a single-arm, prospective, study of an optical imaging device on approximately twenty (20) subjects undergoing lumpectomies at one study site. In vivo and ex vivo imaging will be p...

First Human Dose Trial of NNC0195-0092 in Healthy Subjects

This trial is conducted in Europe. The aim of this trial is to assess safety, tolerability, pharmacokinetics (the exposure of the trial drug in the body) and pharmacodynamics (the effect o...

Observational Study of Nevirapine Extended Release in Human Immunodeficiency Virus (HIV) Patients in Daily Clinical Practice

This Post Marketing Surveillance study will be performed as an open-label, prospective, non-interventional, uncontrolled study in Human immunodeficit Virus-1 (HIV-1) infected patients. Dat...

Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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