Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

16:12 EST 27th February 2015 | BioPortfolio

PubMed Articles [10870 Associated PubMed Articles listed on BioPortfolio]

Linear-array-based photoacoustic imaging of human microcirculation with a range of high frequency transducer probes.

Selective removal of carious human dentin using a nanosecond pulsed laser operating at a wavelength of 5.85  μm.

Journal of cellular physiology: volume 230, number 5, may 2015.

Cover: Protein binding partners of human Notch1 are visualized using the BioGRID website. Only physical interactions are shown and interspecies interactions are excluded. Canonical Notch binding partn...

MAC-T Cells as a Tool to Evaluate Lentiviral Vector Construction Targeting Recombinant Protein Expression in Milk.

Prior to generating transgenic animals for bioreactors, it is important to evaluate the vector constructed to avoid poor protein expression. Mammary epithelial cells cultured in vitro have been propos...

In-vitro Characterization and Evaluation of Apoptotic Potential of Bicistronic Plasmid Encoding HN Gene of Newcastle Disease Virus and Human TNF-α

The viral gene oncotherapy in combination with cytokines emerges as an exciting strategy for cancer therapy due to its minimal side effects and tumor specificity. HN is the surface protein of NDV whic...

Evolutionary behavioral genetics.

We describe the scientific enterprise at the intersection of evolutionary psychology and behavioral genetics-a field that could be termed Evolutionary Behavioral Genetics-and how modern genetic data i...

Actomyosin contractility plays a role in MAP2 expression during nanotopography-directed neuronal differentiation of human embryonic stem cells.

Pluripotent human embryonic stem cells (hESCs) have the capability of differentiating into different lineages based on specific environmental cues. We had previously shown that hESCs can be primed to ...

Fabrication and evaluation of an improved polymer-based cochlear electrode array for atraumatic insertion.

An atraumatic cochlear electrode array has become indispensable to high-performance cochlear implants such as electric acoustic stimulation (EAS), wherein the preservation of residual hearing is signi...

Species-Dependent Chelation of 241Am by DTPA Di-Ethyl Ester.

Diethylenetriaminepentaacetic acid (DTPA) is an FDA-approved chelating agent for enhancing the elimination of transuranic elements such as americium from the body. Early access to therapy minimizes de...

Preventing and controlling zoonotic tuberculosis: a One Health approach.

The expression One Health refers to the unified human and veterinary approach to zoonoses, an approach that used to be identified with Medicine throughout the 20th Century. Zoonotic tuberculosis (TB),...

News Articles [4453 Associated News Articles listed on BioPortfolio]

Support Emerging Among GOP Lawmakers For Short-Term Tax Credits If High Court Strikes Down Health Law Subsidies

Meanwhile, a leading House Republicans says he's heard about a document detailing the Obama administration's contingency plans if the Supreme Court rules against federal exchange subsidies. Such plans...

Novartis's Lung Cancer Drug Recommended for EU Approval

Novartis announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency adopted a positive opinion for Zykadia (ceritinib) to treat adult patients with anapl...

Mystery of the reverse-wired eyeball solved

From a practical standpoint, the wiring of the human eye - a product of our evolutionary baggage - doesn't make a lot of sense. In vertebrates, photoreceptors are located behind the neurons in the bac...

Neurons controlling appetite made from skin cells

Researchers have for the first time successfully converted adult human skin cells into neurons of the type that regulate appetite, providing a patient-specific model for studying the neurophysiology o...

Toujeo® Receives Positive Opinion from the European Regulatory Authorities

Toujeo® Receives Positive Opinionfrom the European Regulatory Authorities Paris, France - February 27, 2015 - Sanofi announced today that the Committee for Medicinal Products f...

Novartis Receives Positive CHMP Opinion For Zykadia

BASEL (dpa-AFX) - Novartis (NVS) announced that the Committee for Medicinal Products for Human Use or CHMP of the European Medicines Agency adopted a positive opinion for Zykadia (ceritinib) to tr...

Triphase, Sunnybrook to advance development new bi-specific antibody for cancer patients

US-based Triphase Accelerator has entered into an academic center collaboration with Canada's Sunnybrook Research Institute to advance development of its new, first-in-class, fully human bi-specific a...

PromoCell – cell culture experts

PromoCell is a biotech company specialized in human primary cells, stem cells and blood cells, as well as optimized cell culture media. PromoCell – cell culture experts PromoCell proposes a wide...

It's time to fix our outdated guidelines for human vaccine trials

Recently, Phase II and III trials of two vaccines for Ebola started in West Africa. The development of possible vaccines is welcome news. Like most vaccine trials, the current Ebola trials are being c...

Antibiotic-resistant listeria in unprocessed salad not as widespread as feared

Antibiotic-resistant strains of the food-poisoning microbe Listeria monocytogenes in unprocessed salad products is not quite as widespread as scientists originally suspected. A new study from Malaysia...

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Companies [268 Associated Companies listed on BioPortfolio]

Station X, Inc.

Station X, Inc. was founded in 2010 by leaders in the fields of genomics and computational biology. The company’s flagship product, GenePool, enables scientists and clinician...

Cerecor Inc.

Driven by an innovative team of industry experts and leading scientists, Cerecor aspires to develop neuroscience drugs that will make a difference. We are committed to improving t...

CanBiocin Inc

CanBiocin was formed in 1998 as a University of Alberta spin-off company to commercialize novel technologies developed from research conducted by professors Michael Stiles, Lynn M...

Ritter Pharmaceuticals, Inc.

Ritter Pharmaceuticals, Inc. develops novel therapeutic products that modulate the human gut microbiome to treat inflammatory, gastrointestinal and metabolic diseases. Ritter i...

Flex Pharma, Inc.

Flex Pharma, Inc. is a biopharmaceutical company dedicated to creating innovative, novel treatments for neuromuscular disorders. Flex Pharma has demonstrated initial human effi...

Octapharma USA, Inc

Headquartered in Lachen, Switzerland, Octapharma is one of the largest human protein products manufacturers in the world and has been committed to patient care and medical innovat...

Hydra Biosciences, Inc

Hydra Biosciences is a biopharmaceutical company developing molecular regeneration medicines, novel cardiovascular therapies and drugs targeting novel ion channels. Tapping the unharnessed power of th...

WaVe Life Sciences

WaVe Life Sciences is leading a revolution in nucleic acid therapeutics and was founded on the core principle that medicines should possess precisely controlled molecular structur...

Voisin Consulting Life Sciences

Voisin Consulting assists biotechnology, pharmaceutical and biomedical companies in the design and implementation of innovative regulatory strategies to expedite product development programs such as d...

North Carolina Research Campus

The Campus is a public-private partnership on 350-acres in Kannapolis (Charlotte); it combines the research power of nine world-renowned universities and colleges, as well as the ...

Clinical Trials [1346 Associated Clinical Trials listed on BioPortfolio]

First-in-human Study to Assess the Safety and Pharmacokinetics of LML134 in Healthy Volunteers

Phase I study to assess the safety, tolerability and pharmacokinetics of ascending single and multiple doses of the investigational medicinal product in healthy volunteers

HIV Attachment Inhibitor to Treat Human Immunodeficiency Virus 1 (HIV-1) Infections

The purpose of this study is to assess the safety, efficacy, tolerability and pharmacokinetics of four doses of BMS-663068 with Raltegravir (RAL) + Tenofovir Disoproxil Fumarate (TDF). At ...

Correlates of Oral Human Papillomavirus Infection in Adolescents and Young Adults With Behaviorally Acquired HIV

The proposed study is a substudy of ATN 106 and a cross sectional study intended to be conducted at each of the AMTUs newly participating in ATN III. The intent is to enroll all youth with...

Phase I Study to Determine the Optimal Human Challenge Dose for a Norovirus GII.4 Challenge Stock (CIN-1)

This is phase I, double blind, placebo-controlled safety and infectivity study of experimental human Norovirus genogroup GII.4 administered to healthy adults 18-49 years of age. Subjects s...

HIV Non-Occupational Post-Exposure Prophylaxis

The purpose of this study is to see if an anti-HIV medication known as Stribild (elvitegravir/cobicistat/emtricitabine/tenofovir DF) is safe, tolerable and acceptable when taken for 28 day...

Safety, Pharmacokinetics and Pharmacodynamics Study With 2B3-201 in Healthy Subjects and Multiple Sclerosis(MS) Patients

In this first in human study the aim is to assess the safety, pharmacokinetics and pharmacodynamics of 2B3-201 in a randomized, first in human, double-blind, placebo- and active comparator...

Assess the Safety and Efficacy of Individually Tailored Prophylaxis With Human-cl rhFVIII in Patients With Severe Haemophilia A

To compare the number of breakthrough bleeds under tailored prophylaxis with human cell line recombinant factor FVIII (Human-cl rhFVIII) with the historical bleeding rate from patients who...

Human Chorionic Gonadotrophin in an Antagonist Protocol

A novel gonadotropin protocol for ovarian stimulation adds low-dose hCG (50- 200 IU) as a source of LH (luteinizing hormone) in the late follicular phase . This regimen reduces the numbe...

Role of Follicular Output Rate in the Prediction of in Vitro Fertilization and Intracytoplasmic Sperm Injection in Women With Unexplained Infertility

300 women with unexplained infertility who are already decided to be treated with ICSI will be recruited from Cairo university hospitals and Dar Al-Teb subfertility centre. On the second ...

Human Papilloma Virus Vaccine Consistency and Non-inferiority Trial in Young Adult Women With GSK Bio HPV-16/18

Human Papilloma virus (HPV) are viruses that cause a common infection of the skin and genitals in men and women. Several types of HPV infection are transmitted by sexual activity and, in w...

Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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