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Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

17:55 EDT 23rd September 2017 | BioPortfolio

PubMed Articles [12284 Associated PubMed Articles listed on BioPortfolio]

In Vitro Differentiation and Propagation of Urothelium from Pluripotent Stem Cell Lines.

Bioengineering of bladder tissue, particularly for those patients who have advanced bladder disease, requires a source of urothelium that is healthy, capable of significant proliferation in vitro and ...

Patient-Derived Bladder Cancer Xenografts.

Patient-derived xenograft (PDX ) tumors are models developed by direct transplant of human tumors into immune-compromised hosts such as nude mice. These models retain the histological and genetic char...

Orthotopic Mouse Models of Urothelial Cancer.

Orthotopic mouse models of urothelial cancer are essential for testing novel therapies and molecular manipulations of cell lines in vivo. These models are either established by orthotopic inoculation ...

Simultaneous Speciation of Selenoproteins and Selenometabolites in Plasma and Serum.

Selenium is an essential element incorporated to different proteins with important biological functions in connection to antioxidant activity, cancer-protective properties, neurodegenerative pathologi...

Radioactive (75)Se Labeling and Detection of Selenoproteins.

The trace element selenium (Se) is incorporated into proteins as the amino acid selenocysteine (Sec), which is cotranslationally inserted into specific proteins in response to a UGA codon. Proteins co...

Detection of Selenoproteins by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP MS) in Immobilized pH Gradient (IPG) Strips.

In contrast to other trace elements that are cofactors of enzymes and removed from proteins under denaturing conditions, Se is covalently bound to proteins when incorporated into selenoproteins, since...

Preparation of Selenocysteine-Containing Forms of Human SELENOK and SELENOS.

Selenoprotein K (SELENOK) and Selenoprotein S (SELENOS) are the members of the endoplasmic-reticulum-associated degradation (ERAD) complex, which is responsible for translocating misfolded proteins fr...

Selenocysteine-Mediated Expressed Protein Ligation of SELENOM.

A sizeable fraction of the selenoproteome encodes oxidoreductases possessing a thioredoxin fold, a structural motif that is shared among a diverse group of enzymes. In these oxidoreductases, the activ...

Simultaneous determination of designer benzodiazepines in human serum using non-aqueous capillary electrophoresis - Tandem mass spectrometry with successive multiple ionic - Polymer layer coated capillary.

A novel non-aqueous capillary electrophoresis - tandem mass spectrometry method for the simultaneous separation, identification and quantification of nine designer benzodiazepines (bentazepam, etizola...

Development and validation of a maleimide-based enzyme-linked immunosorbent assay for the detection of tetrodotoxin in oysters and mussels.

The recent detection of tetrodotoxins (TTXs) in puffer fish and shellfish in Europe highlights the necessity to monitor the levels of TTXs in seafood by rapid, specific, sensitive and reliable methods...

News Articles [4868 Associated News Articles listed on BioPortfolio]

Global Human Micobiome Market Data Survey Report 2025 [Report Updated: 28072017] Prices from USD $1500

SummaryThe Human Microbiome is the collection of all the microorganisms living in association with the human body. These communities consist of a variety of microorganisms including eukaryotes, archae...

News digest – lung cancer drug, vaping, HPV, and… CRISPR genome editing?

Science blog We reported on a promising immunotherapy drug, nivolumab (Opdivo), being made available to certain lung cancer patients in England.

UCI study improves understanding of brain's navigational system

The ability to successfully navigate in the environment is essential both for animals searching for food or escaping predators, as well as for human urban dwellers. It is something we take for granted...

From Ambient to Personal Temperature: Capturing the Experience of Heat Exposure

Heat exposure can have a wide range of adverse effects on the human body.1 But when researchers set out to measure the precise size of those effects across populations, they typically are forced to re...

Human medicines European public assessment report (EPAR): Vosevi, sofosbuvir / velpatasvir / voxilaprevi, Revision: 0, Authorised

Indivumed, Helomics partner on cancer biospecimens

Indivumed and Helomics announce their intentions to collaborate to analyze human cancer biospecimens and annotated clinical data from consenting patients around the world, enabling cutting-edge basic ...

Nature paper describes expansion of Human Microbiome Project

Editing Embryo DNA Yields Clues About Early Human Development

(NPR) – For the first time, scientists have edited the DNA in human embryos to make a fundamental discovery about the earliest days of human development. By modifying a key gene in very early-st...

Push for Three-Parent Technique in Australia to Save Babies from Mitochondrial Disease

(Australian Broadcasting Co) – Scientists are pushing to overhaul human cloning laws in Australia so they can use DNA from three different people to create a baby when there is a risk of the chi...

New lung cell type identified.

There are two classifications of cells in the human body, namely, germ cells which are used to make sperm and eggs, and somatic cells that make up every other cell in the body including lung cells....

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Companies [333 Associated Companies listed on BioPortfolio]

KalVista Pharmaceuticals, Inc.

KalVista Pharmaceuticals, Inc. is a pharmaceuticals company focused on the discovery, development, and commercialization of small molecule protease inhibitors for diseases with si...

Ambry Genetics Corporation

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Prellis Biologics

Prellis Biologics aims to eliminate the wait list for human organ transplants and speed up development of vital new drug therapies. Using innovations in 3D printing and stem cell ...

Cellular Dynamics International (CDI), a FUJIFILM company

Cellular Dynamics International (CDI), a FUJIFILM company, is a leading developer and supplier of human cells used in drug discovery, toxicity testing, and regenerative medicine a...

Eureka Therapeutics, Inc.

Eureka Therapeutics, Inc. is a privately held biotechnology company, headquartered in the San Francisco Bay area, focused on developing first-in-class T cell immunotherapies for h...

Visible Body

Visible Body’s 3D anatomical models and animations of the human body make learning and teaching anatomy and physiology visual and engaging. Visible Body creates apps that adv...

Quidel

Quidel Corporation discovers, develops, manufactures and markets rapid immunodiagnostic products for point-of-care detection of human medical conditions and illnesses. These products provide simple, a...

NewLink Genetics Corporation

NewLink Genetics Corporation is a biopharmaceutical company developing novel drugs and functional genomics solutions with a primary focus on cancer.The successful completion of the Human Genome Projec...

Electricity Human Resources Canada

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Tissue Regenix is a leading medical devices company in the field of regenerative medicine. The company's patented decellularisation ('dCELL®') Technology removes DNA and other ...

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The GAVI® closed vitrification system is a CE labelled device licensed for use in human IVF. It has been developed to standardize the process of vitrification and to increase the safety o...

A Phase 1 Double-Blind First-in-human Study of Orally Administered AL-034

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HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV

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Effects on Nurses' Quality of Working Life of an Educational Intervention to Strengthen Their Humanistic Practice

Haemodialysis (HD) patients constitute a vulnerable population with considerable health needs. They are often older persons with comorbid chronic conditions. Despite the substantial techni...

Panblok H7 Vaccine Adjuvanted With AS03 or MF59 Antigens

The main purpose of this study is to assess the safety and ability of a Panblok H7 influenza vaccine adjuvanted with AS03 or MF59 to generate an immune response after 2 doses separated by ...

Safety Study of Human Neural Stem Cells Injections for Secondary Progressive Multiple Sclerosis Patients

This will be a phase I, open, multicenter, international study performed by 3 participating centres across two countries (Italy and Switzerland). Fifteen to 24 patients affected by SPMS wi...

Comparative Study of Great Ape-caretaker Microbiome

The SHAPES-Captivity study seeks to identify metagenomic components of the intestinal microbiome shared by human beings and captive great apes living in proximity and in direct, daily cont...

Neuromed- Integrated Health Life Platform and Biobank

This project aims to create a digital platform for personal, clinical, diagnostic and environmental data collection, management and analysis of patients with cardiovascular and neurologica...

A Study to Determine the Safety and Immunogenicity of the Candidate Influenza Vaccine MVA-NP+M1

This is a first in human, phase I, open label study of the MVA viral vector (produced in the novel immortalised duck retinal cell line AGE1.CR.pIX) expressing the influenza antigens NP and...

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Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

Methods of detecting pregnancy by examining the levels of human chorionic gonadotropin (HCG) in plasma or urine.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

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