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Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

11:02 EDT 29th May 2017 | BioPortfolio

PubMed Articles [11986 Associated PubMed Articles listed on BioPortfolio]

Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors.

Melanogenesis is a process to synthesize melanin, which is a primary responsible for the pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and chemical reactions are invo...

Carbonic anhydrase inhibitory properties of some uracil derivatives.

Inhibitors of carbonic anhydrase (CA) have been carried out in many therapeutic applications, especially antiglaucoma activity. In this study, we investigated some uracil derivatives (4-12) to inhibit...

Priming increases the anti-tumor effect and therapeutic window of (177)Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1.

(177)Lu-[DOTA(0), Tyr(3)]-octreotate ((177)Lu-octreotate) is used for treatment of patients with somatostatin receptor (SSTR) expressing neuroendocrine tumors. However, complete tumor remission is rar...

Minimum lesion detectability as a measure of PET system performance.

A phantom in combination with an imaging protocol was developed to measure the limit of small lesion detection on different PET systems. Seven small spheres with inner diameters ranging from 3.95 up t...

Advance of autophagy in chronic kidney diseases.

Autophagy, a highly conserved mechanism for cell survival, emerges as an important pathway in many biological processes and diseases conditions. Studies of cultured renal cells, human kidney tissues a...

N-Butyl-2-cyanoacrylate-based injectable and in situ-forming implants for efficient intratumoral chemotherapy.

The local delivery of chemotherapeutic drugs to tumor sites is an effective approach for achieving therapeutic drug concentrations in solid tumors. Injectable implants with the ability to form in situ...

Trace elements in raw milk of buffaloes (Bubalus bubalis) from Campania, Italy.

The profile of 18 trace elements was traced in 68 milk samples collected from buffalo farms in the territory known as the "Land of Fires" in the Campania region (Italy). This area has been polluted by...

A Cisplatin Derivative Tetra-Pt(bpy) as an Oncotherapeutic Agent for Targeting ALT Cancer.

In approximately 15% of human cancers, telomere length is maintained independently of telomerase by the homologous recombination (HR)-mediated alternative lengthening of telomeres (ALT) pathway. Wheth...

High Infection Rates for Adult Macaques after Intravaginal or Intrarectal Inoculation with Zika Virus.

Unprotected sexual intercourse between persons residing in or traveling from regions with Zika virus transmission is a risk factor for infection. To model risk for infection after sexual intercourse, ...

Kinetics of the Human Papillomavirus Type 16 E6 Antibody Response Prior to Oropharyngeal Cancer.

In a European cohort, it was previously reported that 35% of oropharyngeal cancer (OPC) patients were human papillomavirus type-16 (HPV16) seropositive up to 10 years before diagnosis vs 0.6% of cance...

News Articles [5228 Associated News Articles listed on BioPortfolio]

A versatile nanoplatform for synergistic combination therapy to treat human esophageal cancer

Pterostilbene suppresses human endometrial cancer cells in vitro by down-regulating miR-663b

The regioselective glucuronidation of morphine by dimerized human UGT2B7, 1A1, 1A9 and their allelic variants

VIDEO: TxCell Plans First In Man Trial Of Regulatory T-Cells

Stéphane Boissel, CEO of TxCell, discusses the company's plans to advance its lead next-generation regulatory T-cell candidate into human studies...   

OBÉSITÉ : Dès l'adolescence, elle peut mener à l'hypertrophie cardiaque - Society of Human Genetics

Un indice de masse corporelle supérieur à la normale (IMC) est un facteur bien connu de maladie cardiovasculaire en milieu ou en fin de vie, mais cet effet n'a jamais ou peu ét&ea...

Neurimmune Holding AG Pharmaceuticals Healthcare Deals and Alliances Profile [Updated: 10052017] Prices from USD $250

SummaryNeurimmune Holding AG Neurimmune, formerly known as Neurimmune Therapeutics AG is a biopharmaceutical company that develops immunotherapeutics. The company's pipeline products include humanderi...

Oasmia Pharmaceutical AB: Oasmia Pharmaceutical Issues Clarification Regarding Clinical Study OAS-12DOC-BIO

Uppsala, Sweden, 2017-05-29 08:45 CEST (GLOBE NEWSWIRE) -- Oasmia Pharmaceutical AB (NASDAQ: OASM), a developer of a new generation of drugs within human and veterinary oncology, hereby issues a cl...

Stopping production and marketing of tobacco can be the only way to uphold basic human rights

After completing a collaboration with Philip Morris International to develop a “human rights implementation plan,” the Danish Institute for Human Rights concluded that immediately stopping the sal...

Increasing the age limit for Lynch syndrome genetic testing may save lives

(European Society of Human Genetics) Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts ...

New genomic analysis promises benefit in female urinary incontinence

(European Society of Human Genetics) Urinary incontinence in women is common, with almost 50 percent of adult women experiencing leakage at least occasionally. Genetic or heritable factors are known t...

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Companies [323 Associated Companies listed on BioPortfolio]

Alucent Medical, Inc.

Alucent Medical, Inc. is a privately held biotechnology company headquartered in Salt Lake City, Utah. Alucent Medical was founded by Avera Health to develop and market Natural Va...

Chan Zuckerberg Biohub

The CZ Biohub is an independent non-profit medical research organization collaborating with the University of California, Berkeley, Stanford University and the University of Calif...

Tiziana Life Sciences plc

Tiziana Life Sciences plc is a UK biotechnology company that focuses on the discovery and development of novel molecules that treat human disease in oncology and immunology. The C...

Cellular Dynamics International (CDI), a FUJIFILM company

Cellular Dynamics International (CDI), a FUJIFILM company, is a leading developer and supplier of human cells used in drug discovery, toxicity testing, and regenerative medicine a...

Immunomic Therapeutics, Inc.

Immunomic Therapeutics, Inc. (ITI) is a privately-held clinical stage biotechnology company headquartered in Hershey, PA with lab facilities in Rockville, MD. ITI is developing ne...

Evans Incorporated

Evans Incorporated is an award winning, industry leading Consulting and Solutions provider specializing in Human-Centered Solutions in Healthcare, Aviation and International Devel...

KARL STORZ GmbH & Co. KG

Karl Storz began producing instruments for ENT specialists in 1945. His intention was to develop instruments which would enable the practitioner to look inside the human body. The technology available...

TenEleven Group

The TenEleven Group is a software and services company based in Buffalo, NY that provides software solutions for health and human services agencies. Thousands of users in hundreds...

eGenesis

eGenesis is a life sciences company focused on leveraging genome editing technology to deliver safe and effective human transplantable cells, tissues and organs to the hundreds of...

Eccovia Solutions

Eccovia Solutions is a trusted provider of industry-leading software and services for health and human service organizations. As an innovator in cloud-based technology, we are at ...

Clinical Trials [2126 Associated Clinical Trials listed on BioPortfolio]

Carbon Dioxide Laser and Cryotherapy in Treatment of Warts

Viral warts are common skin conditions seen in both children and adults. Human papilloma virus is responsible for verrucae. Cutaneous manifestation of the human papillomavirus, are extreme...

A Safety Surveillance Study in Subjects With Macular Degenerative Disease Treated With Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cell Therapy

The purpose of this study is to is to evaluate the occurrence of late onset (i.e., greater than 5 years after treatment) safety events of special interest in participants who have received...

NLG802 Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors

This is an open-label Phase I study to evaluate the safety, tolerability, and pharmacokinetics of escalating oral doses of NLG802, an investigational agent intended to inhibit the indoleam...

First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide

This clinical trial studies the side effects of 18F-alphavbeta6-binding-peptide and how well it works in imaging patients with primary or cancer that has spread to the breast, colorectal, ...

Assessing the Safety and Efficacy of AVX-012 in Subjects With Mild-to-moderate Dry Eye Syndrome

This is a first-in-human phase I/II randomized, double-blind, placebo (vehicle)-controlled, multicenter study to assess the safety and efficacy of AVX-012 ophthalmic solution in subjects w...

Safety and Efficacy of MEDI0457 and Durvalumab in Patients With HPV Associated Recurrent/Metastatic Head and Neck Cancer

This is a Phase 1b/2a, open-label, multi-center study to evaluate the safety and tolerability, anti-tumor activity, and immunogenicity of MEDI0457 (also known as INO 3112) a HPV DNA vaccin...

Liver Fat and Iron Quantification MRI

The objective of this study is to develop and evaluate novel magnetic resonance imaging (MRI) protocols for studying the structure and function of the human body using 1.5T and 3.0T MRI sc...

Innovations in HIV Testing

The investigators propose to improve HIV prevention and care through expanding HIV testing options to include self-testing for young women, their peers and their sex partners, and by facil...

Controlling Oral Malodor by ClōSYS® Oral Rinse

The purpose of this Study is to assess the efficacy of two ClōSYS Oral Rinse products in human subjects in controlling oral malodor in partial fulfillment of the requirements for American...

Controlling Oral Malodor by ClōSYS Oral Rinse

The purpose of this Study is to assess the efficacy of two ClōSYS Oral Rinse products in human subjects in controlling oral malodor in partial fulfillment of the requirements for recognit...

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Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

Methods of detecting pregnancy by examining the levels of human chorionic gonadotropin (HCG) in plasma or urine.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

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