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Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

02:22 EDT 28th March 2017 | BioPortfolio

PubMed Articles [11737 Associated PubMed Articles listed on BioPortfolio]

Carbonic anhydrase inhibitory properties of some uracil derivatives.

Inhibitors of carbonic anhydrase (CA) have been carried out in many therapeutic applications, especially antiglaucoma activity. In this study, we investigated some uracil derivatives (4-12) to inhibit...

Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors.

Melanogenesis is a process to synthesize melanin, which is a primary responsible for the pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and chemical reactions are invo...

Minimum lesion detectability as a measure of PET system performance.

A phantom in combination with an imaging protocol was developed to measure the limit of small lesion detection on different PET systems. Seven small spheres with inner diameters ranging from 3.95 up t...

Priming increases the anti-tumor effect and therapeutic window of (177)Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1.

(177)Lu-[DOTA(0), Tyr(3)]-octreotate ((177)Lu-octreotate) is used for treatment of patients with somatostatin receptor (SSTR) expressing neuroendocrine tumors. However, complete tumor remission is rar...

Advance of autophagy in chronic kidney diseases.

Autophagy, a highly conserved mechanism for cell survival, emerges as an important pathway in many biological processes and diseases conditions. Studies of cultured renal cells, human kidney tissues a...

Intraoperative intrinsic optical imaging of human somatosensory cortex during neurosurgical operations.

Intrinsic optical imaging as developed by Grinvald et al. is a powerful technique for monitoring neural function in the in vivo central nervous system. The advent of this dye-free imaging has also en...

Reassortant Clade 2.3.4.4 Avian Influenza A(H5N6) Virus in a Wild Mandarin Duck, South Korea, 2016.

A reassortant clade 2.3.4.4 avian influenza A(H5N6) virus was isolated from a fecal sample of a Mandarin duck (Aix galericulata) in South Korea during October 2016. This virus was genetically similar ...

Insight into halloysite nanotubes-loaded gellan gum hydrogels for soft tissue engineering applications.

A tri-component hydrogel, based on gellan gum (GG), glycerol (Gly) and halloysite nanotubes (HNT), is proposed in this work for soft tissue engineering applications. The FDA-approved GG polysaccharide...

A new unsaturated derivative of hyaluronic acid - Synthesis, analysis and applications.

Hyaluronic acid (HA) containing CC double bond in positions 4 and 5 of N-acetyl-glucosamine ring (ΔHA) is an unique material, which could be used for biomedical applications and cosmetics. The main a...

Formulation of olfactory-targeted microparticles with tamarind seed polysaccharide to improve nose-to-brain transport of drugs.

Targeted delivery and retention of drug formulations in the olfactory mucosa, the target site for nose-to-brain drug absorption is a major challenge due to the geometrical complexity of the nose and n...

News Articles [5070 Associated News Articles listed on BioPortfolio]

U.S. Department of Health and Human Services Pharmaceuticals Healthcare Deals and Alliances Profile [Updated: 24022017] Prices from USD $250

SummaryU.S. Department of Health and Human Services HHS is a healthcare service provider that offers patient care and support services. The organization's service areas include health insurance market...

Jellagen jellyfish collagen for cell culture

Collagen is abundant in all connective tissue, which makes it one of the most studied biomaterials of the extracellular matrix. Innovation with collagen biomaterials is witnessing significant growth, ...

Why the Rise of AI Makes Human Intelligence More Valuable Than Ever

SOURCE In the popular TV show Sherlock, visual depictions of our hero’s deductive reasoning often look like machine algorithms. And probably not by accident, given... Read More →

Study shows how epigenetic randomness helps cancer cells proliferate

In a research effort that merged genetics, physics and information theory, a team at the schools of medicine and engineering at The Johns Hopkins University has added significantly to evidence that la...

The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells

Philly.com Names SPIN, Inc. a Winner of the Delaware Valley 2017 Top Workplaces Award

For the eighth year in a row, SPIN, Inc. (Special People in Northeast) has been awarded a Top Workplaces honor by Philly.com. SPIN ranks among the top 12 large companies to...

Revisited: The Regenerative Power of Pig Guts

Bioengineers have made great strides harnessing the body’s ability to start over, whether regenerating heart tissue and bones, or using stem cells to regrow fingertips. Still, much of regenerative m...

Bartell introduces treatment for minor medical care needs

Brian BerkVia network of certified pharmacists, the types of care varies with patient needs, but examples include treatments for ailments such as insect stings, urinary tract infections, seasonal alle...

Southeast Regional Symposium on Mitochondrial Medicine Planned for April 7-8 in Birmingham, AL

The Foundation for Mitochondrial Medicine and The United Mitochondrial Disease Foundation are co-sponsors of the Southeast Regional Symposium on Mitochondrial Medicine, scheduled ...

Humacyte receives FDA RMAT designation for Humacyl in vascular access for hemodialysis

Humacyte, an innovator in biotechnology and regenerative medicine, announced that the FDA has granted Humacyl, its investigational human acellular vessel (HAV), the Regenerative Medicine Advanced Ther...

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Companies [317 Associated Companies listed on BioPortfolio]

TenEleven Group

The TenEleven Group is a software and services company based in Buffalo, NY that provides software solutions for health and human services agencies. Thousands of users in hundreds...

eGenesis

eGenesis is a life sciences company focused on leveraging genome editing technology to deliver safe and effective human transplantable cells, tissues and organs to the hundreds of...

Eccovia Solutions

Eccovia Solutions is a trusted provider of industry-leading software and services for health and human service organizations. As an innovator in cloud-based technology, we are at ...

Ajinomoto Co., Inc.

Ajinomoto is a global manufacturer of high-quality seasonings, processed foods, beverages, amino acids, pharmaceuticals and specialty chemicals. For many decades Ajinomoto has con...

Immunomic Therapeutics, Inc. (ITI)

Immunomic Therapeutics, Inc. (ITI) is a privately-held clinical stage biotechnology company headquartered in Hershey, PA with lab facilities in Rockville, MD. ITI is developing ne...

Vycellix, Inc.

Vycellix, Inc. is a closely-held biotechnology company advancing innovative products designed to enhance cellular therapies, facilitate manufacturing processes and optimize human ...

Tri-Source Pharma

Established in 2016, Tri-Source Pharma was formed for capital investment and management oversight of its subsidiary companies. Its goal is to grow and synergize each of its compan...

Chan Zuckerberg Biohub

The CZ Biohub is an independent non-profit medical research organization collaborating with the University of California, Berkeley, Stanford University and the University of Calif...

Abilita Bio Inc.

Founded in 2014, Abilita Bio is an innovation-driven biotechnology company focused on enabling the discovery and development of drugs targeting challenging human membrane proteins...

Axial Biotherapeutics

Axial Biotherapeutics is a biopharmaceutical company harnessing the link between the human gut microbiome and the central nervous system to develop a new class of biotherapeutics ...

Clinical Trials [2073 Associated Clinical Trials listed on BioPortfolio]

Impact of Recombinant Human Growth Hormone on HIV Persistence

Antiretroviral therapy (ART) has improved the health of more than 18 million people infected with HIV by controlling viral replication, AIDS and non-AIDS events, and by reducing the risk o...

Optimizing Treatment on Idiopathic Inflammatory Myopathies

As a T2T, our patients with idiopathic inflammatory myopathies will receive pulse therapies with methyprednisolone and/or human intravenous immunoglobulin, or only methyprednisolone at dis...

Evaluating Genomic Testing in Human Cancer & Outcomes of Targeted Therapies

This is a substudy (Part 2) of a larger two-part clinical trial including both observational and therapeutic (interventional) cohorts to assess the progression free survival ratio of patie...

Alveolar Management Following Teeth Extraction

Investigation of the volume stability of the alveolar ridge, the bone structure and soft tissue appearance at a delayed dental implantation using two bone substitute materials (1. Human-Sp...

Characterization of Human Autoantibody Titers After Central Nervous System Insult

The aim of the study is to quantitate Central Nervous System (CNS) autoantibody development in human blood using ELISA after human brain injury, spinal cord injury, and intra-axial brain s...

A Study to Investigate the Regional Brain Kinetics of Brain Drug Transporters Using P-glycoprotein and Breast Cancer Resistance Protein Substrates and by Using the Positron Emission Tomography Ligand 11C-JNJ-63779586 in the Human Brain

The purpose of this study is to investigate the total body biodistribution and radiation dosimetry of 11C-JNJ-63779586 by Positron Emission Tomography (PET) in healthy young adult males (P...

Prospective Study on Efficacy and Safety of SCYX-7158 in Patients Infected by Human African Trypanosomiasis Due to T.b. Gambiense

The goal of this study is to assess efficacy and safety of SCYX-7158 given as a single dose oral treatment for adult patients (above or equal 15) in the fasting state with T.b. Gambiense H...

Haploidentical Stem Cell Transplantation Using Post-Transplant Cyclophosphamide

Historically, the best results of allogeneic SCT have been obtained when the stem cell donor is a human leukocyte antigen (HLA)-matched sibling, however, this is only available for approxi...

Metformin in Intracytoplasmic Sperm Injection Cycles

The relationship between serum progesterone level on the day of human chorionic gonadotropin administration and outcome of in vitro fertilization /intracytoplasmic sperm injection and embr...

Clinical Safety & Efficacy of a New Infant Formula With Specific Medical Purpose Containing Human Milk Oligosaccharides

The primary objective of the study is to show that infants with cow milk protein allergy (CMPA) fed with a new FSMP infant formula with reduced level of protein & with 2 Human Milk Oligosa...

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Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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