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Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

04:43 EDT 26th May 2016 | BioPortfolio

PubMed Articles [11352 Associated PubMed Articles listed on BioPortfolio]

Difficulties facing healthcare workers in the era of AIDS treatment in Lesotho.

Sub-Saharan Africa is most affected by the AIDS pandemic and Lesotho is no exception. In many countries, healthcare workers are at the forefront of the fight against AIDS. This study explores the diff...

Pre-clinical evaluation of eight DOTA coupled gastrin-releasing peptide receptor (GRP-R) ligands for in vivo targeting of receptor-expressing tumors.

Overexpression of the gastrin-releasing peptide receptor (GRP-R) has been documented in several human neoplasms such as breast, prostate, and ovarian cancer. There is growing interest in developing ra...

Design and conduct of the activated protein C and corticosteroids for human septic shock (APROCCHSS) trial.

We aimed at assessing the benefit-to-risk ratio of activated protein C (drotrecogin-alfa activated, DAA) and corticosteroids, given alone or in combination, in patients with septic shock.

Possible Transmission of mcr-1-Harboring Escherichia coli between Companion Animals and Human.

Improved stability and controlled release of CLA with spray-dried microcapsules of OSA-modified starch and xanthan gum.

The objective of this investigation was to improve the stability of CLA and to allow for its controlled release by encapsulating it with combinations of octenyl-succinic anhydride (OSA) starch and xan...

Three dimensional alginate-fucoidan composite hydrogel augments the chondrogenic differentiation of mesenchymal stromal cells.

Presence of sulfated polysaccharides like heparan sulphate has often been implicated in the regulation of chondrogenesis. However, recently there has been a plethora of interest in the use of non-anim...

Development of chitosan/β-glycerophosphate/glycerol hydrogel as a thermosensitive coupling agent.

This work develops a dual-function thermosensitive hydrogel to prevent overheating, a side effect of focused ultrasound therapy. The proposed hydrogel has the components of chitosan, β-glycerophospha...

Probing the G‑quadruplex from hsa-miR-3620-5p and inhibition of its interaction with the target sequence.

G-quadruplexes have been reported to exist both in human genome and transcriptome and are of great interests due to their important biological functions. Up to now, the formation and property of G-qua...

Aptamer functionalized hydrophilic polymer monolith with gold nanoparticles modification for the sensitive detection of human α-thrombin.

Low abundant proteins of body fluids participate nearly all physiological processes and indicate various kinds of diseases. The development of specific enrichment techniques is the key to identify and...

A fast method for bisphenol A and six analogues (S, F, Z, P, AF, AP) determination in urine samples based on dispersive liquid-liquid microextraction and liquid chromatography-tandem mass spectrometry.

In this study, a novel method combining dispersive liquid-liquid microextraction (DLLME) and fast liquid chromatography coupled to mass spectrometry (LC-MS/MS) was developed and validated for the extr...

News Articles [5032 Associated News Articles listed on BioPortfolio]

Genes linked to the effects of mood and stress on longevity identified

The visible impacts of depression and stress that can be seen in a person's face -- and contribute to shorter lives -- can also be found in alterations in genetic activity, according to newly publishe...

UN chief lauds Pfizer’s decision to ban use of its drugs in executions

The United Nations high commissioner for human rights has praised pharmaceutical company Pfizer’s decision to ban the sale and distribution of its drugs to prisons for use in executions by lethal i...

“Frontiers in Human Microbiota Symbiotic Interactions” 3rd Annual Meeting of the Bridging Biomedical Worlds Series

Wednesday, May 25th 2016 at 7:00am UTC HONG KONG–(BUSINESS WIRE)– The third “Bridging Biomedical Worlds” meeting, entitled “Frontiers in Human Microbiota Symbiotic Interactions” wa...

Technology Advancements in Protein Therapeutics Spurring Market Growth

Protein drugs have gained importance for their therapeutic applications, and the numbers of products have increased in recent years. BCC Research reveals in its new report that novel technologies such...

Human amyloid-beta acts as natural antibiotic in the brain: Alzheimer's-associated amyloid plaques may trap microbes

A new study provides additional evidence that amyloid-beta protein -- which is deposited in the form of beta-amyloid plaques in the brains of patients with Alzheimer's disease -- is a normal part of t...

UofL expands oncology research with addition of 33,000 human tissue samples

The University of Louisville has expanded its oncology research strength through the addition of approximately 33,000 human tissue samples and specimens. The samples were transferred by Catholic Healt...

Human amyloid-beta acts as natural antibiotic in the brains of animal models

A new study from Massachusetts General Hospital (MGH) investigators provides additional evidence that amyloid-beta protein - which is deposited in the form of beta-amyloid plaques in the brains of pat...

Humans less likely to return to an automated advisor once given bad advice

The ubiquitous Chat Bot popping up on websites asking if you need help has become standard on many sites. We dismiss, we engage, but do we trust the algorithm that is aiding our experience? Giving us ...

Next-Generation Fitness Trackers May Attach Directly To Your Skin

Researchers have developed a small, wearable patch capable of monitoring both biochemical and electric signals in the human body that could be more accurate that your current fitness tracker.

Association between lutein intake and lutein concentrations in human milk samples from lactating mothers in South Korea

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Companies [316 Associated Companies listed on BioPortfolio]

Eccovia Solutions

Eccovia Solutions is a trusted provider of industry-leading software and services for health and human service organizations. As an innovator in cloud-based technology, we are at ...

Effective Health Systems, LLC

Effective Health Systems (www.effectivehealthsystems.com) was launched in 2007. Effective Health Systems is a human capital management firm whose focus is on delivering technologi...

Biomoda

Biomoda, Inc. is a developmental stage company engaged in the business of developing biopharmaceutical technology to diagnose and treat human diseases. The Company currently licenses two patents in th...

The International WELL Building Institute

The International WELL Building Institute (IWBI) is a for-benefit organization (B-Corp) whose mission is to improve human health and wellbeing through the built environment. IWBI ...

Mawi DNA Technologies

Mawi DNA Technologies was founded in 2013 and has developed and commercialized the iSWAB technology, an innovative system for collection of biosamples. The company’s flags...

Octapharma Group

Headquartered in Lachen, Switzerland, Octapharma is one of the largest human protein manufacturers in the world, developing and producing human proteins from human plasma and huma...

Unite US

Unite US is a technology platform reinventing the delivery of health, employment, and human services. The company is disrupting the fragmented health and human services industry b...

MOLOGEN AG

MOLOGEN is specializing in selected areas of Molecular Medicine. Our areas of competence are gene expression, gene therapy and bioinformatics. We are dedicated to the development of DNA expression and...

SAB Biotherapeutics, Inc.

SAB Biotherapeutics, Inc. (SAB), headquartered in Sioux Falls, S.D. is an established, biopharmaceutical company that is leading the science and manufacturing of immunoglobulin th...

Sandbox

Launched in 2016, Sandbox is an independent, full-service agency formed by four complementary entrepreneurial agencies united by a "play well together" ethos of collaboration. Hea...

Clinical Trials [1740 Associated Clinical Trials listed on BioPortfolio]

Study of Recombinant Human Serum Albumin/Interferon alpha2b Fusion Protein in Chinese Healthy Volunteers

The purpose of this study is to evaluate the dosages of recombinant human serum albumin/interferon alpha2b fusion protein injection in healthy subjects.

Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)

A 52 week trial of TransCon hGH (ACP-011), a long-acting growth hormone product, versus human growth hormone therapy. TransCon hGH will be given once-a-week, human growth hormone (hGH) wil...

A Safety Study of Human Cord Blood Derived, Culture Expanded Natural Killer Cell (PNK-007) Infusion With Subcutaneous Recombinant Human IL-2 (rhIL-2) in Adults With Relapsed and/or Refractory Acute Myeloid Leukemia (AML)

This study will find the highest acceptable treatment dose of cord blood, culture expanded natural killer (NK) cells, a kind of immune cell, in patients with relapsed and/or refractory acu...

Human Papillomavirus (HPV) Self-sampling as a Test of Cure After Treatment of Cervical Intra-epithelial Neoplasia

The purpose of this study is to evaluate the performance of HPV self-sampling (self-HPV) in detecting residual/recurrent disease in women treated by loop electro-surgical excision (LEEP) f...

Parkinsonian Brain Repair Using Human Stem Cells

Implantation of Celavie human stem cells (OK99) is intended to address the underlying pathology of the disease by replacing damaged/destroyed cells of the brain, and/or stimulating the pat...

PfSPZ Challenge in Non-immune Adults in Baltimore, USA

This is a single center, randomized and controlled human study to optimize controlled human malaria infection (CHMI) administered by direct venous inoculation (DVI). 36 healthy adults aged...

A Study of AL2846 on Tolerance and Pharmacokinetics

To study the pharmacokinetic characteristics of Anlotinib in the human body, recommend a reasonable regimen for subsequent research.

18431-Sun Protection Factor Assay

To evaluate the Sun Protection Factor efficacy on human skin.

18432-Sun Protection Factor Assay

To evaluate the Sun Protection Factor efficacy on human skin.

18572 - Sun Protection Factor Assay

To evaluate the Sun Protection Factor efficacy on human skin.

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Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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