Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

11:48 EST 28th November 2014 | BioPortfolio

PubMed Articles [10654 Associated PubMed Articles listed on BioPortfolio]

In-vitro Characterization and Evaluation of Apoptotic Potential of Bicistronic Plasmid Encoding HN Gene of Newcastle Disease Virus and Human TNF-α

The viral gene oncotherapy in combination with cytokines emerges as an exciting strategy for cancer therapy due to its minimal side effects and tumor specificity. HN is the surface protein of NDV whic...

MAC-T Cells as a Tool to Evaluate Lentiviral Vector Construction Targeting Recombinant Protein Expression in Milk.

Prior to generating transgenic animals for bioreactors, it is important to evaluate the vector constructed to avoid poor protein expression. Mammary epithelial cells cultured in vitro have been propos...

Preventing and controlling zoonotic tuberculosis: a One Health approach.

The expression One Health refers to the unified human and veterinary approach to zoonoses, an approach that used to be identified with Medicine throughout the 20th Century. Zoonotic tuberculosis (TB),...

Variation of mineral composition in different parts of taro (Colocasia esculenta) corms.

Taro (Colocasia esculenta) is an important root crop in the humid tropics and a valuable source of essential mineral nutrients. In the presented study, we compared the mineral compositions of four mai...

Stable isotope and trace metal compositions of Australian prawns as a guide to authenticity and wholesomeness.

This research has explored the potential of stable isotope and trace metal profiles to distinguish Australian prawns from prawns imported from neighbouring Asian countries. Australian prawns were coll...

In vitro genotoxicity of mycotoxins ochratoxin A and fumonisin B1 could be prevented by sodium copper chlorophyllin - Implication to their genotoxic mechanism.

The aim of this study was to investigate the possible protective effect of sodium copper chlorophyllin (CHL) against cytotoxicity and DNA damage induced by mycotoxins ochratoxin A (OTA) and fumonisin ...

Characterisation of interaction between food colourant allura red AC and human serum albumin: Multispectroscopic analyses and docking simulations.

Binding interaction of human serum albumin (HSA) with allura red AC, a food colourant, was investigated at the molecular level through fluorescence, ultraviolet-visible, circular dichroism (CD) and Ra...

Restricted access carbon nanotubes for direct extraction of cadmium from human serum samples followed by atomic absorption spectrometry analysis.

In this paper, we propose a new sorbent that is able to extract metal ions directly from untreated biological fluids, simultaneously excluding all proteins from these samples. The sorbent was obtained...

Reverse genetic engineering of the human rhinovirus serotype 16 genome to introduce an antibody-detectable tag.

The ability to accurately detect viral proteins during infection is essential for virology research, and the lack of specific antibodies can make this detection difficult. Reverse genetic engineering ...

Reverse genetics system for studying human rhinovirus infections.

Human rhinovirus (HRV) contains a 7.2 kb messenger-sense RNA genome which is the template for reproducing progeny viruses after it enters the cytoplasm of a host cell. Reverse genetics refers to the r...

News Articles [5291 Associated News Articles listed on BioPortfolio]

Novartis’ heart failure drug LCZ696 granted accelerated assessment by CHMP

Swiss drug major Novartis announced that the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has granted accelerated assessment to LCZ696, an investigational medici...

Duality in the human genome

Humans don't like being alone, and their genes are no different. Together we are stronger, and the two versions of a gene – one from each parent – need each other. Scientists at the Max Planck Ins...

Novartis: CHMP Grants Accelerated Assessment To Heart Failure Medicine LCZ696

BASEL (dpa-AFX) - Swiss pharmaceutical giant Novartis AG (NVS) said the Committee for Medicinal Products for Human Use or CHMP has granted accelerated assessment to LCZ696, an investigational medi...

γ134.5-deleted HSV-1-expressing human cytomegalovirus IRS1 gene kills human glioblastoma cells as efficiently as wild-type HSV-1 in normoxia or hypoxia

[Correspondence] Dose regimen of favipiravir for Ebola virus disease

Although several antivirals have shown efficacy against Ebola virus infection in vitro or in animal models, none of them have been yet assessed in human beings with Ebola virus disease.

[Comment] HPV transmission in adolescent men who have sex with men

Men who have sex with men (MSM) have a substantial burden of disease associated with human papillomavirus (HPV) infection, including anogenital warts, anal cancer, penile cancers, and oropharyngeal ca...

[Articles] Site-specific human papillomavirus infection in adolescent men who have sex with men (HYPER): an observational cohort study

High incidence rates suggest that the vaccination coverage in MSM will need to be high. The transmission estimates will inform HPV modelling.

Social media data contain pitfalls for understanding human behavior

A growing number of academic researchers are mining social media data to learn about both online and offline human behavior. In recent years, studies have claimed the ability to predict everything fro...

Human medicines European public assessment report (EPAR): Emselex, darifenacin hydrobromide, Revision: 17, Authorised

Needle-Free Drug Delivery Will Improve Treatments in the Global Human Growth Hormone Market: TechNavio

The Global Human Growth Hormone (HGH) Market is expected to grow at a CAGR of 4.22 percent from 2015-2019, in response to increased demand for HGH treatments, says research...

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Companies [256 Associated Companies listed on BioPortfolio]

Quartet Medicine

Quartet Medicine is a private, biotechnology company focused on discovering and developing novel treatments for chronic pain and inflammation. Human genetics and preclinical targe...

The International WELL Building Institute

The International WELL Building Institute (IWBI) is a for-benefit organization (B-Corp) whose mission is to improve human health and wellbeing through the built environment. IWBI ...

Mucosis B.V.

Mucosis B.V. (Mucosis) is a clinical-stage biotechnology company using a proprietary technology platform to develop next-generation needle-free human vaccines for infectious disea...

Lab7 Systems, Inc.

Lab7 Systems is a software developer that has a vision to reduce the level of hands-on data management by bioinformaticians, scientists, and IT teams who are struggling with the m...

AnthroTronix

AnthroTronix, based in Silver Spring, Md., is a research and development (R&D) company that designs human-inspired products that define the future of mobile technology. AnthroTron...

Watson Inc.

Watson is one of the highest quality suppliers of products and services geared towards enhancing human health and nutrition around the world. We are a leader in developing quality...

Complete Genomics, Inc.

Complete Genomics is a leader in whole human genome sequencing based in Mountain View, California. Using its proprietary sequencing instruments, chemistry, and software, the compa...

Arcadia Biosciences

Arcadia Biosciences was founded in 2002 to pursue agriculture-based business opportunities that improve the environment or human health.Arcadia identifies and develops promising technologies. The Comp...

Vaxart, Inc.

Vaxart is a privately owned company developing oral recombinant vaccines based on its proprietary delivery platform. The Vaxart platform is suitable to deliver any protein vaccine...

International Conference on Human Milk Science and Innovation

About International Conference on Human Milk Science and Innovation

Clinical Trials [1322 Associated Clinical Trials listed on BioPortfolio]

Safety of and Immune Response to the Human Papillomavirus (HPV) Vaccine in HIV-Infected Women

Human papillomavirus (HPV) is the most common sexually transmitted disease in the world. HPV infection can cause genital warts and certain cervical problems, including cervical cancer. HPV...

A First-In-Human Study of RO5503781 in Patients With Advanced Malignancies, Except Leukemia

This multicenter, open label, dose-escalating study will evaluate the safety, ph armacokinetics, pharmacodynamics and efficacy of RO5503781 in patients with adva nced malignancies except l...

Evaluation of Molecular Forms of PSA and Human Kallikrein 2 in a Cohort of Patients With Locally Resected Prostate Cancer But Biochemical Recurrence

The purpose of this study is to investigate if a new blood test looking at PSA and a group of PSA related proteins in a patient's blood can indicate which men after surgery with a rising P...

Next Generation to Identify Genetic Causes of Disease in Patients Participating in NICHD Clinical Protocols

Background: - The purpose of this study is to identify changes in genes that cause human diseases. We would like to obtain some of you or your child s DNA and test for changes in genes ...

Protein Synthesis in the Brain of Patients With Fragile X Syndrome

Biosynthesis of proteins is essential for growth and continued maintenance of the entire neuron including axons, dendrites, and synaptic terminals, and it is clearly one of the important b...

Human Papillomavirus Infection and Related Anal Lesions in HIV-positive Men Who Have Sex With Men

Multicentric epidemiological non-comparative study in France characterising evolution of anal Human papillomavirus (HPV) infection and related lesions and evaluating markers associated wit...

Prospective Observational Epidemiologic Study of Maraviroc's Safety

The study will assess if use of maraviroc along with an optimized background regimen of antiretroviral drugs in usual clinical practice is as safe as using only an optimized regimen of ant...

Evaluation of a Human Acellular Dermal Matrix in Post Mastectomy Reconstruction

Use of a HADM and implant in post-mastectomy breast reconstruction.

The Healthy Elderly Longevity Cohort

With the completion of the human genome project, investigators can now explore new questions in human biology. Previously human genetics focused on highly penetrant, Mendelian traits; how...

Pegylated Recombinant Human Arginase 1 in Combination With Oxaliplatin and Capecitabine for the Treatment of HCC

The propose of the study is to evaluate the maximum tolerated dose (MTD) of Oxaliplatin in combination with pegylated recombinant human arginase 1 (PEG-BCT-100) and Capecitabine and effica...

Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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