Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

06:20 EDT 28th April 2015 | BioPortfolio

PubMed Articles [11082 Associated PubMed Articles listed on BioPortfolio]

Corrigendum.

Laboral health in Penitentiary Center of Chile: a look from policies of human resources.

This article examines the influence of human resources policies on occupational health variables, such as engagement and job satisfaction, with regard to Chilean prison employees. 80 workers at the Wo...

A mathematical model of HTLV-I infection with two time delays.

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Helicobacter pylori induces IL-1β and IL-18 production in human monocytic cell line through activation of NLRP3 inflammasome via ROS signaling pathway.

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Silver nanoparticles-enhanced rare earth co-luminescence effect of Tb(III)-Y(III)-dopamine system.

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Label-free nucleic acids detection based on DNA templated silver nanoclusters fluorescent probe.

Based on DNA templated Ag NCs (DNA/Ag NCs) fluorescent probe, a label-free fluorescent method was developed for the detection of clinical significant DNA fragments from human immunodeficiency virus ty...

Aptamer-based organic-silica hybrid affinity monolith prepared via "thiol-ene" click reaction for extraction of thrombin.

A novel strategy for preparing aptamer-based organic-silica hybrid monolithic column was developed via "thiol-ene" click chemistry. Due to the large specific surface area of the hybrid matrix and the ...

Biomaterials for promoting periodontal regeneration in human intrabony defects: a systematic review.

Intrabony periodontal defects are a frequent complication of periodontitis and, if left untreated, may negatively affect long-term tooth prognosis. The optimal outcome of treatment in intrabony defect...

Animal models for peri-implant mucositis and peri-implantitis.

The treatment of infectious diseases affecting osseointegrated implants in function has become a demanding issue in implant dentistry. Since the early 1990s, preclinical data from animal studies have ...

Wound models for periodontal and bone regeneration: the role of biologic research.

The ultimate goals of periodontal therapy remain the complete regeneration of those periodontal tissues lost to the destructive inflammatory-immune response, or to trauma, with tissues that possess th...

News Articles [4256 Associated News Articles listed on BioPortfolio]

Understanding multicellular function and disease with human tissue-specific networks

Olga Troyanskaya and colleagues present genome-wide functional interaction networks for 144 human tissues and cell types. They identify important disease-gene associations by combining data from GWAS ...

Improved genome inference in the MHC using a population reference graph

Gil McVean, Alexander Dilthey and colleagues present a graphical model-based method for accurate genomic assembly that uses the diversity present in multiple reference sequences, as represented by a p...

X-ray laser reveals structure of blood pressure regulator

With a sophisticated X-ray analysis, a US-German team of scientists has solved the molecular structure of an important regulator for blood pressure in the human body. The study gives new insights int...

Tyson Foods plans to cut human antibiotics in U.S. chicken flocks by 2017

CHICAGO, April 28 (Reuters) - Tyson Foods Inc, the largest U.S. poultry producer, plans to eliminate the use of human antibiotics in its chicken flocks by September 2017 - one of the most aggressive t...

Efficacy and safety of CDX-301, recombinant human Flt3L, at expanding dendritic cells and hematopoietic stem cells in healthy human volunteers

Human herpesvirus-6 encephalitis after allogeneic hematopoietic cell transplantation: What we do and do not know

Sequencing and beyond: integrating molecular 'omics' for microbial community profiling

In this Review, Huttenhower and colleagues discuss how integrating multi-omic data types — including genomics, transcriptomics, proteomics and metabolomics — enables a better characterization of t...

Codeine contraindicated in children

The use of codeine for cough and cold is now contraindicated in children aged under 12 years, and is not recommended in children and adolescents aged 12–18 years who have breathing difficulties. The...

Chinese scientists edit genes of human embryos

Chinese scientists report the first-ever genetic modification of human embryos using the CRISPR/Cas9 gene-editing technique, confirming rumours that these highly controversial experiments were underwa...

Lexicon To Report First Quarter 2015 Financial Results On April 29, 2015

THE WOODLANDS, Texas, April 27, 2015 /PRNewswire/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on developing breakthrough treatments for human disease, wil...

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Proteo Biotech AG

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PF-06342674 (RN168), being developed for the treatment of multiple sclerosis (MS), is an antibody that binds to and inhibits the human interleukin-7 receptor, a component potentially invol...

Relative Bioavailability Study of Candesartan Cilexetil Under Fasting Conditions

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Anticancer Activity of Nicotinamide on Lung Cancer

Nicotinamide is an inhibitor of human sirtuins (HDAC III), and is found to re-activate epigenetically silenced tumor suppressors, RUNX3 (runt-related gene 3) and others, in cancer cells. N...

Angioshield First-In-Human Study to Demonstrate the Preliminary Safety and Efficacy

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MK2461 in Patients With Advanced Cancer (2461-001)(COMPLETED)

This is a first-in-human trial to establish the safety, tolerability, Recommended Phase II Dose (RP2D), pharmacodynamic, and clinical activity of MK2461.

Endometrial Luteal Phase Characteristics and Luteal Phase Support in Controlled Ovarian Stimulation Protocols With GnRH Antagonists:Focusing on MicroRNA

MiRNAs are single-stranded small non-coding RNAs that act on specific mRNAs to regulate the gene expression. Studies have suggested that miRNAs influence cellular activities in the uterus...

Study of Radium-223 Dichloride Versus Placebo and Hormonal Treatment as Background Therapy in Subjects With Bone Predominant HER2 (Human Epidermal Growth Factor Receptor 2) Negative Hormone Receptor Positive Metastatic Breast Cancer

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Treatment of SCID Due to ADA Deficiency With Autologous Transplantation of Cord Blood or Hematopoietic CD 34+ Cells After Addition of a Normal Human ADA cDNA by the EFS-ADA Lentiviral Vector

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Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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