Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

09:07 EDT 20th October 2014 | BioPortfolio

PubMed Articles [9971 Associated PubMed Articles listed on BioPortfolio]

Preventing and controlling zoonotic tuberculosis: a One Health approach.

The expression One Health refers to the unified human and veterinary approach to zoonoses, an approach that used to be identified with Medicine throughout the 20th Century. Zoonotic tuberculosis (TB),...

Variation of mineral composition in different parts of taro (Colocasia esculenta) corms.

Taro (Colocasia esculenta) is an important root crop in the humid tropics and a valuable source of essential mineral nutrients. In the presented study, we compared the mineral compositions of four mai...

Stable isotope and trace metal compositions of Australian prawns as a guide to authenticity and wholesomeness.

This research has explored the potential of stable isotope and trace metal profiles to distinguish Australian prawns from prawns imported from neighbouring Asian countries. Australian prawns were coll...

UPLC-MS/MS method for determination of selected pyrrolizidine alkaloids in feed.

Alkaloids known as secondary metabolites are grouped by typical structural characteristics into large families such as pyrrolizidine alkaloids (PAs) comprising more than 350 individual heterocyclic co...

In vitro genotoxicity of mycotoxins ochratoxin A and fumonisin B1 could be prevented by sodium copper chlorophyllin - Implication to their genotoxic mechanism.

The aim of this study was to investigate the possible protective effect of sodium copper chlorophyllin (CHL) against cytotoxicity and DNA damage induced by mycotoxins ochratoxin A (OTA) and fumonisin ...

Characterisation of interaction between food colourant allura red AC and human serum albumin: Multispectroscopic analyses and docking simulations.

Binding interaction of human serum albumin (HSA) with allura red AC, a food colourant, was investigated at the molecular level through fluorescence, ultraviolet-visible, circular dichroism (CD) and Ra...

Restricted access carbon nanotubes for direct extraction of cadmium from human serum samples followed by atomic absorption spectrometry analysis.

In this paper, we propose a new sorbent that is able to extract metal ions directly from untreated biological fluids, simultaneously excluding all proteins from these samples. The sorbent was obtained...

Reverse genetic engineering of the human rhinovirus serotype 16 genome to introduce an antibody-detectable tag.

The ability to accurately detect viral proteins during infection is essential for virology research, and the lack of specific antibodies can make this detection difficult. Reverse genetic engineering ...

Reverse genetics system for studying human rhinovirus infections.

Human rhinovirus (HRV) contains a 7.2 kb messenger-sense RNA genome which is the template for reproducing progeny viruses after it enters the cytoplasm of a host cell. Reverse genetics refers to the r...

A Protocol to Express and Isolate HRV16 3C Protease for Use in Protease Assays.

Human rhinovirus (HRV) proteases are highly conserved across serotypes and have very similar target specificity. However, there are some serotype-specific differences in their action. It is therefore ...

News Articles [5357 Associated News Articles listed on BioPortfolio]

Humacyte Selected to Join U.S. Secretary of Commerce On Trade Mission to Asia

Humacyte, a pioneer in regenerative medicine, today announced it will join U.S. Secretary of Commerce Penny Pritzker on a Development Mission to Japan and South Korea later this m...

Baxter Launches HYQVIA in the United States for Adult Patients with Primary Immunodeficiency

Baxter International Inc. (NYSE:BAX) and Halozyme Therapeutics, Inc., (NASDAQ:HALO) today announced the launch and first shipments of HYQVIA [Immune Globulin Infusion 10% (Human) ...

RainDance Technologies Showcases Leading Genomic Researchers and Novel Sequencing Solutions at American Society of Human Genetics Annual Meeting

Dr. Arthur Beaudet and Dr. Kejian Zhang to discuss how the ThunderStorm® NGS Content Enrichment System is transforming research of carrier screening and heterogeneous inherited d...

Personalis and the Garvan Institute Announce Commercial Partnership for Whole Human Genome Sequencing, Analysis and Interpretation

Collaboration to Bring Together High-Quality, Large-Scale Whole Genome Sequencing With Best-in-Class Analysis and Interpretation Services for Research and Clinical Applications ...

China Biologic gets approval to manufacture human prothrombin complex concentrate at Shandong Taibang facility

China Biologic Products, a leading fully integrated plasma-based biopharmaceutical company in China, announced that the company has received approval from the China Food and Drug Administration for co...

Study on blind cave fish could reveal mechanisms behind eye disease, other human ailments

Blind cave fish may not be the first thing that comes to mind when it comes to understanding human sight, but recent research indicates they may have quite a bit to teach us about the causes of many h...

BioNano Genomics Announces One Human : One Chip : One Day

SAN DIEGO, Oct. 20, 2014 /PRNewswire/ -- BioNano Genomics announced today achievement of a major milestone for the Irys system: the ability to collect human data at 30X depth, sufficient for a ge...

Researchers Identify “Naïve-Like” Human Stem Cells

In their search for the earliest possible stage of development of human embryonic stem cells (hESCs) that still have the potential to develop into any types of body cells and tissue, researchers from...

Mucosis Presents Data on Intranasal RSV Vaccine SynGEM® at Vaccines 2014 Conference

Mucosis B.V., a clinical stage biotechnology company using a proprietary technology platform to develop next-generation needle-free human vaccines for infectious diseases, will pr...

First GMP-Compliant Batch of a Biologic Drug Substance from a Moss Expression System Produced for Clinical Use

greenovation Biotech GmbH and BIOMEVA GmbH announced today the successful production of the world's first GMP (Good Manufacturing Practice)-compliant batch of drug substance manufactured in moss for c...

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Companies [251 Associated Companies listed on BioPortfolio]

Mucosis B.V.

Mucosis B.V. (Mucosis) is a clinical-stage biotechnology company using a proprietary technology platform to develop next-generation needle-free human vaccines for infectious disea...

Lab7 Systems, Inc.

Lab7 Systems is a software developer that has a vision to reduce the level of hands-on data management by bioinformaticians, scientists, and IT teams who are struggling with the m...

AnthroTronix

AnthroTronix, based in Silver Spring, Md., is a research and development (R&D) company that designs human-inspired products that define the future of mobile technology. AnthroTron...

Watson Inc.

Watson is one of the highest quality suppliers of products and services geared towards enhancing human health and nutrition around the world. We are a leader in developing quality...

Complete Genomics, Inc.

Complete Genomics is a leader in whole human genome sequencing based in Mountain View, California. Using its proprietary sequencing instruments, chemistry, and software, the compa...

Arcadia Biosciences

Arcadia Biosciences was founded in 2002 to pursue agriculture-based business opportunities that improve the environment or human health.Arcadia identifies and develops promising technologies. The Comp...

Vaxart, Inc.

Vaxart is a privately owned company developing oral recombinant vaccines based on its proprietary delivery platform. The Vaxart platform is suitable to deliver any protein vaccine...

International Conference on Human Milk Science and Innovation

About International Conference on Human Milk Science and Innovation

DiscoveryBioMed, Inc.

DiscoveryBioMed, Inc. is a life sciences and biotechnology company that engages in R&D and services work in human cell engineering and production and human cell-based drug discove...

Cerecor Inc.

Driven by an innovative team of industry experts and leading scientists, Cerecor aspires to develop neuroscience drugs that will make a difference. We are committed to improving t...

Clinical Trials [1291 Associated Clinical Trials listed on BioPortfolio]

An Open Label Pharmacokinetic, Safety And Efficacy Study Of Maraviroc In Combination With Background Therapy For The Treatment Of HIV-1 Infected, CCR5 -Tropic Children

The primary purpose of this study is to determine the pharmacokinetic properties (what the body does to maraviroc) and to determine a suitable dosing schedule of maraviroc in HIV-1 infecte...

A Phase IIIb Study of the Safety, Efficacy, and Tolerability of Switching to a Fixed-dose Combination of Abacavir/Dolutegravir/ Lamivudine From Current Antiretroviral Regimen

This study is a 48-week, Phase IIIb, randomly assigned, open-label, active-controlled, multicenter, parallel group, non-inferiority study. This study is designed to demonstrate the non-inf...

Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.

The main purpose of this first human study with CC-115 is to assess the safety and action of a new class of experimental drug (dual DNA-PK and TOR kinase inhibitors) in patients with advan...

Effects of Controlled Ovarian Hyperstimulation (COH) With Letrozole and Gonadotropin

Fertility drugs have the effect of increasing hormone levels. Higher hormone levels from infertility treatments may increase breast cancer risk, but there has not been enough research to k...

Feasibility Study of Human Umbilical Cord Tissue-Derived Mesenchymal Stem Cells in Patients With Multiple Sclerosis

Allogeneic human umbilical cord tissue-derived stem cells injected intravenously (IV) once per day for 7 days is a safe and will induce a therapeutic effect in multiple sclerosis (MS) pati...

PRO 140 for Human Immunodeficiency Virus Infection

PRO 140 2103 is a multicenter, randomized parallel group study, conducted in male and female adult subjects infected with CCR5-tropic HIV-1.

The Role of Metformin and Colesevelam in Human GLP-1 Secretion

Our primary hypothesis is that bile acid sequestrant colesevelam and the antidiabetic drug metformin potentiates the secretion of the gut hormone glucagon-like peptide 1 (GLP-1).

Efficacy and Tolerability Study of V501 in Japanese Males (V501-122)

A study to evaluate the efficacy, immunogenicity, and tolerability of V501 (quadrivalent Human Papilloma Virus [HPV] [Type 6, 11, 16 and 18] L1 Virus-Like Particle vaccine, GARDASIL™) in...

A Phase III Study to Compare Efficacy and Safety of AFOLIA vs. Gonal-f® in Infertile Women 35 to 42 Years of Age Undergoing in Vitro Fertilization (IVF)

The purpose of this study is to show that AFOLIA, a recombinant manufactured human follicle stimulating hormone (r-hFSH) has a similar efficacy and safety profile compared to the widely us...

MK0518 in the Treatment of HIV-Infected Patients Switched From a Protease Inhibitor Regimen (0518-033)(TERMINATED)

The purpose of this study is to investigate the efficacy, safety, and tolerability of an investigational treatment for patients with Human Immunodeficiency Virus (HIV).

Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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