Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

12:49 EDT 30th June 2015 | BioPortfolio

PubMed Articles [11398 Associated PubMed Articles listed on BioPortfolio]

Corrigendum.

Human Chromosome Y and Haplogroups; introducing YDHS Database.

As the high throughput sequencing efforts generate more biological information, scientists from different disciplines are interpreting the polymorphisms that make us unique. In addition, there is an i...

A nerve guidance conduit with topographical and biochemical cues: potential application using human neural stem cells.

Despite major advances in the pathophysiological understanding of peripheral nerve damage, the treatment of nerve injuries still remains an unmet medical need. Nerve guidance conduits present a promis...

Effect of discarded keratin-based biocomposite hydrogels on the wound healing process in vivo.

Biocompatible keratin-based hydrogels prepared by electron beam irradiation (EBI) were examined in wound healing. As the EBI dose increased to 60kGy, the tensile strength of the hydrogels increased, w...

Silver nanoparticles with antimicrobial activities against Streptococcus mutans and their cytotoxic effect.

Microbial resistance represents a challenge for the scientific community to develop new bioactive compounds. The goal of this research was to evaluate the antimicrobial activity of silver nanoparticle...

Curcumin-reduced graphene oxide sheets and their effects on human breast cancer cells.

Curcumin (as a natural reductant material) was utilized for green reduction and functionalization of chemically exfoliated graphene oxide (GO) sheets. The π-π attachment of the curcumin molecules on...

Exploration of attenuated total reflectance mid-infrared spectroscopy and multivariate calibration to measure immunoglobulin G in human sera.

Immunoglobulin G (IgG) is crucial for the protection of the host from invasive pathogens. Due to its importance for human health, tools that enable the monitoring of IgG levels are highly desired. Con...

A simple and sensitive electrochemical immunosensor based on thiol aromatic aldehyde as a substrate for the antibody immobilization.

In this work, a novel sulfur-containing compound with aldehyde groups was synthesized, which was used to immobilize antibodies through the covalent bonding of the aldehyde groups with amino groups, in...

Label-free and homogeneous aptamer proximity binding assay for fluorescent detection of protein biomarkers in human serum.

By using the aptamer proximity binding assay strategy, the development of a label-free and homogeneous approach for fluorescent detection of human platelet-derived growth factor BB (PDGF-BB) is descri...

Sandwich-format electrochemiluminescence assay for PDGF-BB using quantum dots-dendrimer nanocomposites as probe.

This work describes a novel electrochemiluminescence aptasensor for highly sensitive detection of platelet-derived growth factor BB (PDGF-BB) using aptamer functionalized CdS quantum dots-polyamidoami...

News Articles [4259 Associated News Articles listed on BioPortfolio]

STEMCELL Technologies Launches Innovative Products to Support CAR T Cell Research

STEMCELL Technologies Inc. announces the launch of ImmunoCult™ Human T Cell Activator reagents and ImmunoCult™-XF T Cell Expansion Medium to support T cell researchers ...

Neural signatures of human fear conditioning: an updated and extended meta-analysis of fMRI studies

Treatment With PI3K Inhibitors May Cause Cancers to Become Aggressive, Metastatic

The enzyme phosphatidylinositol-3 kinase (PI3K) appears to be exploited in almost every type of human cancer, making it the focus of considerable interest as a therapeutic target, with many PI3K-inhib...

Discover the Real Beef About Meat

With the average cow producing 1000 times more methane than a human, meat production plays a big role in greenhouse gas emissions. But in a world where there’s a growing appetite for meat, how can o...

A gut feeling about immunity

As it becomes evident that the microbiome exerts an influence on the human immune system, scientists have begun to ponder therapies that might act on intestinal microbes to reduce harmful inflammation...

The emerging role of resident memory T cells in protective immunity and inflammatory disease

Tissue-resident memory T cells are increasingly being linked to human tissue-specific immune and inflammatory disease. These roles are discussed in this review.

Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient‐specific neural cells

Standardization of culture methods for human pluripotent stem cell (PSC) neural differentiation can greatly contribute to the development of novel clinical advancements through the comprehension of ne...

FDA's New HCT/P Draft Guidance Document: What is Minimal Manipulation in 2015?

On December 23, 2014, the FDA announced a new draft guidance document entitled “Minimal Manipulation of Human Cells, Tissues, and Cellular and Tissue-Based Products” (the “draft guidance documen...

Identification, by systematic RNA sequencing, of novel candidate biomarkers and therapeutic targets in human soft tissue tumors

Clinical significance of the integrin α6β4 in human malignancies

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Companies [286 Associated Companies listed on BioPortfolio]

Ritter Pharmaceuticals, Inc.

Ritter Pharmaceuticals, Inc. develops novel therapeutic products that modulate the human gut microbiome to treat inflammatory, gastrointestinal and metabolic diseases. Ritter i...

Paycom Software, Inc.

As a leader in payroll and HR technology, Oklahoma City-based Paycom redefines the human capital management industry by allowing companies to effectively navigate a rapidly changi...

Square Roots

Square Roots is a life sciences company focused on integrating new technology and scientific findings to examine, improve and optimize the state of maternal and infant care. We ar...

Arcadia Biosciences, Inc.

Based in Davis, Calif., with additional facilities in Seattle, Wash. and Phoenix, Ariz., Arcadia Biosciences is an agricultural technology company focused on developing technologi...

KellyOCG

Kelly offers a competitive advantage to biopharmaceutical sponsors in the Life Sciences market sector predicated upon 65 years of success in deploying experienced talent during th...

Allele Biotechnology & Pharmaceuticals, Inc.

Allele Biotechnology and Pharmaceuticals, Inc. is a private, San Diego-based company that explores the mechanisms of biological processes to develop technologies and products for ...

FocusMotion

Founded in 2013, FocusMotion is a Los Angeles-based company using innovative, proprietary technology to track a broad range of human movement. FocusMotion is assembling the world...

Trophogen, Inc.

Trophogen, Inc. is a U.S.-based biotechnology company founded in 2001 with Series A funding from Toucan Capital, in late stage preclinical focusing on development of human and bov...

i-Human Patients, Inc. (IHP)

i-Human Patients, Inc. (IHP) develops virtual medical training products and services, including its flagship i-Human Patients® platform, launched in November 2012, which educat...

dorsaVi Ltd

dorsaVi Ltd (ASX: DVL) is an ASX company focused on developing innovative motion analysis device technologies for use in clinical practice, elite sports, and occupational health a...

Clinical Trials [1433 Associated Clinical Trials listed on BioPortfolio]

Gonadotropin-Releasing Hormone Agonist for the Preservation of Ovarian Function During Chemotherapy in Premenopausal Breast Cancer

The study is a prospective randomized control clinical trial which is sponsored by the researchers. The purpose of this study is to determine the effectiveness of Gonadotropin-Releasing ho...

Impact of the Virtual Human Project on Team-based Learning: A Randomized-controlled Trial

Team-based learning (TBL) is a learner-centered, instructor-directed strategy for small group active learning in large group educational settings. When TBL is conducted correctly, the stud...

Metabolic Changes in the Activated Human Visual Cortex During Mild Hypoxia

The primary objective of this research is to measure neurochemicals in the activated human brain during both normoxia (normal oxygen availability) and induced mild hypoxia (reduced oxygen ...

Comparison of Two Different Alveolar Ridge Preservation Techniques

The purpose of this study is to compare two barrier membrane products, Cytoplast (dPTFE) and BioXclude (human amnion chorion allograft), for their relative efficacies in dental socket pres...

Study to Evaluate the Safety and Immunogenicity of 'IL-YANG Flu Vaccine Quadrivalent Inj' in Healthy Korean Adults

This study evaluates the safety, tolerability and immunogenicity of IL-YANG quadrivalent vaccine versus IL-YANG trivalent vaccine after a single intramuscular administration in healthy Kor...

Pharmacokinetic Study of Cabotegravir Long-acting in Healthy Adult Volunteers

Cabotegravir (CAB) long-acting (LA) is a promising candidate for human immunodeficiency virus (HIV) pre exposure prophylaxis (PrEP) due to its potent antiretroviral activity and infrequent...

Using Ex-vivo Normothermic Machine Perfusion With the Organox Metra™ Device to Store Human Livers for Transplantation

This trial will examine the safety and feasibility of using the OrganOx Metra device to transport and store donor livers under normothermic conditions prior to transplantation. Participant...

Bone Mineral Density in Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Adult Subjects Switching From a Tenofovir Regimen to a Dolutegravir Plus Rilpivirine Regimen

The purpose of this study is to evaluate any change from baseline in bone mineral density (BMD) in subjects following the switch from a triple antiretroviral therapy (ART) regimen containi...

Impact of Butyricicoccus Pullicaecorum in Healthy Subjects

During this project the safety, tolerability and effect on gut microbiota of oral administration of Butyricicoccus pullicaecorum was investigated in healthy human volunteers by a placebo-c...

Hepatic RFA Increases T Cell Infiltraion and PD-L1 Expression in Primary Colorecatl Cancer

It has been shown that RFA induced systemic tumor antigen-specific T cell responses in human carcinoma. However, there are insufficient studies on the immune modulation of tumor microenvir...

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Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).


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