Human Chorionic Gonadotropin Hcg rDNA - Biotech, Pharma and Life Science Channel

05:05 EST 31st January 2015 | BioPortfolio

PubMed Articles [10698 Associated PubMed Articles listed on BioPortfolio]

Selective removal of carious human dentin using a nanosecond pulsed laser operating at a wavelength of 5.85  μm.

Linear-array-based photoacoustic imaging of human microcirculation with a range of high frequency transducer probes.

Journal of cellular physiology: volume 230, number 5, may 2015.

Cover: Protein binding partners of human Notch1 are visualized using the BioGRID website. Only physical interactions are shown and interspecies interactions are excluded. Canonical Notch binding partn...

In-vitro Characterization and Evaluation of Apoptotic Potential of Bicistronic Plasmid Encoding HN Gene of Newcastle Disease Virus and Human TNF-α

The viral gene oncotherapy in combination with cytokines emerges as an exciting strategy for cancer therapy due to its minimal side effects and tumor specificity. HN is the surface protein of NDV whic...

MAC-T Cells as a Tool to Evaluate Lentiviral Vector Construction Targeting Recombinant Protein Expression in Milk.

Prior to generating transgenic animals for bioreactors, it is important to evaluate the vector constructed to avoid poor protein expression. Mammary epithelial cells cultured in vitro have been propos...

Evolutionary behavioral genetics.

We describe the scientific enterprise at the intersection of evolutionary psychology and behavioral genetics-a field that could be termed Evolutionary Behavioral Genetics-and how modern genetic data i...

Preventing and controlling zoonotic tuberculosis: a One Health approach.

The expression One Health refers to the unified human and veterinary approach to zoonoses, an approach that used to be identified with Medicine throughout the 20th Century. Zoonotic tuberculosis (TB),...

New patterns in human biogeography revealed by networks of contacts between linguistic groups.

Human languages differ broadly in abundance and are distributed highly unevenly on the Earth. In many qualitative and quantitative aspects, they strongly resemble biodiversity distributions. An intrig...

Variation of mineral composition in different parts of taro (Colocasia esculenta) corms.

Taro (Colocasia esculenta) is an important root crop in the humid tropics and a valuable source of essential mineral nutrients. In the presented study, we compared the mineral compositions of four mai...

Stable isotope and trace metal compositions of Australian prawns as a guide to authenticity and wholesomeness.

This research has explored the potential of stable isotope and trace metal profiles to distinguish Australian prawns from prawns imported from neighbouring Asian countries. Australian prawns were coll...

News Articles [5208 Associated News Articles listed on BioPortfolio]

Will nanotechnology soon allow you to ‘swallow the doctor’?

SOURCE January 29, 2015 Story highlights Advancements in nanotechnology have created robots small enough to enter the human body Using magnets, they can be steered to the desired location to target di...

Prezcobix from Janssen Therapeutics granted FDA approval

Ryan ChavisJanssen Therapeutics on Thursday announced that the Food and Drug Administration has approved its Prezcobix (darunavir 800 mg/cobicistat 150 mg) tablets. The drug is used to treat human imm...

UPDATE 1-U.S. proposes effort to analyze DNA from 1 million people

WASHINGTON, Jan 30 (Reuters) - The United States has proposed analyzing genetic information from more than 1 million American volunteers as part of a new initiative to understand human disease and dev...

OPKO Submits Investigational New Drug Application to Initiate a Phase 2a Trial for its Long-Acting Coagulation Factor VIIa-CTP to Treat Hemophilia

OPKO Health, Inc. (NYSE:OPK) announced the submission of an Investigational New Drug Application (IND) to the U.S. Food and Drug Administration (FDA) to conduct a Phase 2a study ...

HHS issues three-year plan to reach electronic health interoperability

Michael JohnsenThe Department of Health and Human Services’ Office of the National Coordinator for Health Information Technology on Friday released a draft roadmap toward the safe and secure exc...

New Pew Survey Shows The Public Disagrees With Scientists On GMOs, Climate Change

A new Pew survey compares the attitudes of 3,748 scientists (members of the American Association for the Advancement of Science) to those of 2,002 members of the general public and reveals scientists ...

Healthpointe’s Los Angeles Clinic Welcomes Dr. Mark Nario

Dr. Nario brings his chiropractic specialties to Healthpointe in Los Angeles County La Mirada, CA (PRWEB) January 30, 2015 Healthpointe, a multidisciplinary medical provider in Southern California, p...

UK to launch 100,000 genomes project as Obama backs DNA drive

LONDON, Jan 30 (Reuters) - Gene research is getting a boost on both sides of the Atlantic, with scientists in England set to launch a project on Feb. 2 to analyse 100,000 entire human genomes and U.S....

Janssen's PREZCOBIX gets FDA approval to treat adults living with HIV-1

Janssen Therapeutics, Division of Janssen Products, LP (Janssen), announced the U.S. Food and Drug Administration (FDA) has approved PREZCOBIX (darunavir 800 mg/cobicistat 150 mg) tablets, an HIV-1 pr...

Oral HPV Infection in HIV-Infected and HIV-Uninfected Adults

Human papillomavirus now causes the majority of oropharyngeal cancers in the US. This study examines the risk factors for and natural history of oral HPV incidence in HIV-infected and at-risk adults. ...

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Companies [263 Associated Companies listed on BioPortfolio]

Voisin Consulting Life Sciences

Voisin Consulting assists biotechnology, pharmaceutical and biomedical companies in the design and implementation of innovative regulatory strategies to expedite product development programs such as d...

Flex Pharma, Inc.

Flex Pharma, Inc. is a biopharmaceutical company dedicated to creating innovative, novel treatments for neuromuscular disorders. Flex Pharma has demonstrated initial human effi...

North Carolina Research Campus

The Campus is a public-private partnership on 350-acres in Kannapolis (Charlotte); it combines the research power of nine world-renowned universities and colleges, as well as the ...

Opsona Therapeutics Ltd

Opsona is a leading immunology drug development company, focused on novel therapeutic approaches to key targets of the innate immune system associated with a wide range of majo...

Humacyte, Inc.

Humacyte, Inc., a privately held company founded in 2004, is a medical research, discovery and development company with clinical and pre-clinical stage investigational products. H...

Endonovo Therapeutics, Inc.

Endonovo Therapeutics, Inc. is a publicly traded biotechnology company developing off the-shelf, cell-free regenerative products and non-invasive, bioelectronic therapies designed...

Lifecode, Inc.

Lifecode is a specialized CLIA certified clinical laboratory focused on the genetic basis of human disease. With an initial focus on oncology, we are committed to improving the li...

Liberty Behavioral Health Corporation

Liberty Behavioral Health Corporation is an affiliate of Liberty Healthcare Corporation, a Philadelphia-based health care and human services management company with a diverse port...

Hydra Biosciences, Inc

Hydra Biosciences is a biopharmaceutical company developing molecular regeneration medicines, novel cardiovascular therapies and drugs targeting novel ion channels. Tapping the unharnessed power of th...

Contextual Genomics

Contextual Genomics believes that DNA analysis significantly improves human health and that geography should not be a barrier to the benefits of using molecular information to gui...

Clinical Trials [1331 Associated Clinical Trials listed on BioPortfolio]

A First-in-Human Safety and Dose-Finding Study of New Type-16 Human Rhinovirus (RG-HRV16) Inoculum in Healthy Volunteers

This research study will test different doses of RG-HRV16 to find the minimum dose needed to give research subjects cold symptoms of at least moderate intensity. The study will also test t...

Gene Therapy for WAS

This is a phase I/II study to evaluate the safety and efficacy of Hematopoietic Stem Cell genetherapy for the Wiskott-Aldrich Syndrome.

A Double-blinded, Randomised, Three-period Crossover Euglycaemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Human Insulin, Human Insulin (Huminsulin® Normal) and Insulin Lispro (Humalog®) in Subjects With Ty

The addition of BioChaperone to already marketed prandial human insulin preparations may accelerate the onset and shorten the duration of action due to facilitation of the insulin absorpti...

Cervical Intraepithelial Neoplasm (CIN) in Women (Gardasil)(V501-015)

The primary purpose of the study is to determine if Gardasil (V501) an investigational vaccine with 4 components is able to prevent cervical cancer.

Prochymal™ Adult Human Mesenchymal Stem Cells for Treatment of Moderate-to-severe Crohn's Disease

Human mesenchymal stem cells (MSCs), derived from healthy adult volunteer human donors, can be obtained from bone marrow donation and cultured in the laboratory. MSCs have shown the abilit...

Evaluation of Skin, Colonic, and Oral Microbiome and Effect of Time and Antibiotic Treatment on Organism Diversity at Each Site

Background: - Most studies of infectious agents have focused on specific microbes, such as human papillomaviruses and cervical cancer, and the hepatitis B and C virus and liver ca...

Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes Mellitus

This is a multicenter, randomized, partial-blinded, five-arm, placebo-controlled study of human plasma-derived alpha1-proteinase inhibitor (alpha1-PI) in children (ages 6-11 years old) and...

Intestinal Permeability in Obesity

In rodents, obesity is associated with changes in tight junctions' structure in small intestine, which impacts intestinal permeability and results in metabolic complications. Few data exis...

Safety and Efficacy of Recombinant Human Acid Alpha-Glucosidase in the Treatment of Classical Infantile Pompe Disease

Pompe disease is caused by a deficiency of a critical enzyme in the body called acid alpha glucosidase (GAA). Normally, GAA is used by the body's cells to break down glycogen (a stored fo...

An Open Label Pharmacokinetic, Safety And Efficacy Study Of Maraviroc In Combination With Background Therapy For The Treatment Of HIV-1 Infected, CCR5 -Tropic Children

The primary purpose of this study is to determine the pharmacokinetic properties (what the body does to maraviroc) and to determine a suitable dosing schedule of maraviroc in HIV-1 infecte...

Medical and Biotech [MESH] Definitions

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

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