Interstitial Cystitis - Biotech, Pharma and Life Science Channel
PubMed Articles
Although intestinal microbiota are essential for the development of T cell-mediated colitis, it remains undetermined whether they enhance or suppress the chronic extraintestinal inflammation that ofte...
Rotating-shield brachytherapy for cervical cancer.
In this treatment planning study, the potential benefits of a rotating shield brachytherapy (RSBT) technique based on a partially-shielded electronic brachytherapy source were assessed for treating ce...
Oxygen doped SiC nanocrystals: first principles study of the optical properties.
We have studied a typical spherical SiC nanocrystal with a diameter of 1.2 nm (Si43C44H76) using linear combination of atomic orbitals in combination with pesudopotential density functional calculati...
Zyxin Regulates Cell Migration and Differentiation in EMT during Chicken AV Valve Morphogenesis.
During heart valve development, epithelial-mesenchymal transformation (EMT) is a key process for valve formation. EMT leads to the generation of mesenchymal cells that will eventually become the inter...
MUC5B promoter polymorphism and interstitial lung abnormalities.
A common promoter polymorphism (rs35705950) in MUC5B, the gene encoding mucin 5B, is associated with idiopathic pulmonary fibrosis. It is not known whether this polymorphism is associated with interst...
In systemic sclerosis (SSc), impaired diffusing capacity for carbon monoxide (DLCO) can indicate interstitial lung disease (ILD), pulmonary hypertension (PH), and/or other disease manifestations, incl...
Intravital analysis of vascular permeability in mice using two-photon microscopy.
Blood vessel endothelium forms a semi-permeable barrier and its permeability controls the traffics of plasma contents. Here we report an intravital evaluation system for vascular permeability in mice...
The use of MRI-guided laser-induced thermal ablation for epilepsy.
PURPOSE: Epilepsy surgery is constantly researching for new options for patients with refractory epilepsy. MRI-guided laser-induced thermal ablation for epilepsy is an exciting new minimally invasive...
Differential expression of long non-coding RNAs in bleomycin-induced lung fibrosis.
Recent studies suggest that long non‑coding RNAs (lncRNAs) are more involved in human diseases than previously realized. A growing body of evidence links lncRNA mutation and dysregulation to diverse...
Immune cells control skin lymphatic electrolyte homeostasis and blood pressure.
The skin interstitium sequesters excess Na+ and Cl- in salt-sensitive hypertension. Mononuclear phagocyte system (MPS) cells are recruited to the skin, sense the hypertonic electrolyte accumulation in...
News Articles
TOKYO, June 14, 2013 - Astellas Pharma Inc. (“Astellas”; Tokyo:4503; President and CEO: Yoshihiko Hatanaka) announced today that it has been granted approval in Japan for the additional...
On June 4, 2013, the Interstitial Cystitis Association, an organization advocating for about 12 million Americans with a painful chronic bladder condition, led a group, including the International Adh...
Transbronchial Biopsy Is Useful in Predicting UIP Pattern
What do you need to know to correctly diagnose Idiopathic Pulmonary Fibrosis and separate it from other interstitial pneumonias? Respiratory Research
ImportanceCurrent prediction models of mortality in idiopathic pulmonary fibrosis (IPF), which are based on clinical and physiological parameters, have modest value in predicting which patients will p...
Stem Cell Therapeutics' Clinical Advisor and Collaborator Receives Prestigious National Award
TORONTO, ONTARIO -- (Marketwired) -- 06/04/13 -- Stem Cell Therapeutics Corp. (TSX VENTURE: SSS) (OTCQX: SCTPF), a biopharmaceutical company developing cancer stem cell-related therapeutics, today a...
Dr. Ramirez of Weston, FL has been named a Patients' Choice Award Winner for 2012
WESTON, Fla., May 28, 2013 /PRNewswire-USNewswire/ -- Among the select few physicians honored with the prestigious Patients' Choice Award this year is Dr. Jose F Ramirez-Cleveland Clinic Florida - Wes...
Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo
Neutrophil recruitment from blood to extravascular sites of sterile or infectious tissue damage is a hallmark of early innate immune responses, and the molecular events leading to cell exit from the b...
Trillium Therapeutics completes dosing in Phase I study of TTI-1612
Trillium Therapeutics, a wholly owned subsidiary of Stem Cell Therapeutics, has completed dosing of patients with interstitial cystitis/bladder pain syndrome (IC/BPS) in first phase study of TTI-1612.
Data Show Promise of PRM-151 in Diseases Involving Fibrosis Promedior, Inc., a clinical stage biotechnology company developing novel biologic therapeutics for th...
Events
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Companies
TARIS Biomedical Inc., a specialty pharmaceutical company with deep domain expertise in therapeutics and drug-delivery, is focused on local minimally-invasive drug-device converge...
Guided Therapeutics, Inc. (OTCBB: GTHP) is developing a rapid and painless test for the early detection of disease that leads to cervical cancer. The technology is designed...
Clinical Trials
Neurosurgical Use of Interstitial Laser Therapy (ILT)
The researchers' specific aims are to test the following hypotheses: Hypothesis 1: A tumor can be completely ablated by ILT with MRI-guidance. Hypothesis 2: The MRI-based 3D temperature...
Botox as a Treatment for Interstitial Cystitis in Women
Patients with interstitial cystitis have been well documented to have pelvic floor muscle tenderness as well as pain on bladder distension. Some investigators have even suggested that pel...
Laser Therapy of Benign Thyroid Nodules
Nodular goitre is common in the general population and less than 5% of the patients who undergo surgery for solitary thyroid nodules have cancer, in absence of clinical suspicion. Nodu...
Comparison of TransMID vs Standard Treatment of Cancerous Brain Tumors
Study Objectives: Primary Objective: To evaluate the efficacy of intratumoral/interstitial therapy with TransMID compared to best standard of care in patients with progressive and/...
Popcorn Lung: the Discovery of a New Disease
Recently, an epidemic of pulmonary disease has been recognized among workers in a popcorn factory in Jasper, Missouri. The exposure agent has not yet been identified, but suspects include...
Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma
IL13-PE38QQR is an oncology drug product consisting of IL13 (interleukin-13) and PE38QQR (a bacteria toxin). IL3-PE38QQR is a protein that exhibits cell killing activity against a variety...
RATIONALE: Radiofrequency interstitial tissue ablation may kill tumor cells by heating tumors to several degrees above body temperature. PURPOSE: This phase II trial is studying radiofreq...
OBJECTIVES: I. Estimate the optimal safe dose of intravesical capsaicin in patients with interstitial cystitis. II. Evaluate the efficacy of 0.025% topical capsaicin in relieving chroni...
Azathioprine and Prednisone in the Treatment of Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a diffuse lung disease, associated with the histological appearance of usual interstitial pneumonia (UIP), with an inexorably deteriorating clinical...
The Occurence of Inflammation and Oxidative Stress in Lung Diseases
Reactive oxygen species (ROS) are suggested to play a pivotal role in ILD. Little is known, however, about the endogenous antioxidant levels in ILD that can offer protection against ROS. I...
Videos
Managing Interstitial Cystitis Flares (Interstitial Cystitis Network)
Are you newly diagnosed and confused about what IC flares are? ICN President Jill Osborne talks about the two most common types of flares, how to recognize t...
Medical and Biotech [MESH] Definitions
Leukocyte L1 Antigen Complex
A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity.
Leptospira Interrogans Serovar Canicola
A serovar of the bacterial species LEPTOSPIRA INTERROGANS, whose natural host is DOGS where disease is characterized by GASTROENTERITIS, and INTERSTITIAL NEPHRITIS.
Mycoplasma Ovipneumoniae
A species of gram-negative bacteria originally isolated from the LUNGS; TRACHEA; and NASAL CAVITY of SHEEP. It causes chronic interstitial pneumonia (PNEUMONIA, MYCOPLASMA) in both SHEEP and GOATS.
Nocturia
Frequent URINATION at night that interrupts sleep. It is often associated with outflow obstruction, DIABETES MELLITUS, or bladder inflammation (CYSTITIS).
Idiopathic Interstitial Pneumonias
A group of interstitial lung diseases with no known etiology. There are several entities with varying patterns of inflammation and fibrosis. They are classified by their distinct clinical-radiological-pathological features and prognosis. They include IDIOPATHIC PULMONARY FIBROSIS; CRYPTOGENIC ORGANIZING PNEUMONIA; and others.
