Iron Overload - Biotech, Pharma and Life Science Channel
PubMed Articles
Objective-To investigate cardiovascular changes and survival times following complete interventional device occlusion of uncomplicated left-to-right shunting patent ductus arteriosus in dogs. Design-R...
Bioavailable affinity label for collagen prolyl 4-hydroxylase.
Collagen is the most abundant protein in animals. Its prevalent 4-hydroxyproline residues contribute greatly to its conformational stability. The hydroxyl groups arise from a post-translational modifi...
Micro-electrolysis of Cr (VI) in the nanoscale zero-valent iron loaded activated carbon.
In this paper we prepared a novel material of activated carbon/nanoscale zero-valent iron (C-Fe(0)) composite. The C-Fe(0) was proved to possess large specific surface area and outstanding reducibilit...
Ionic liquids (ILs) have potential applications in many areas of chemical industry because of their unique properties. However, it has been shown that the ILs commonly used to date are toxic and not b...
Effect and mechanism of persulfate activated by different methods for PAHs removal in soil.
The influence of persulfate activation methods on polycyclic aromatic hydrocarbons (PAHs) degradation was investigated and included thermal, citrate chelated iron, and alkaline, and a hydrogen peroxid...
Degradation of p-nitrophenol in a BES-Fenton system based on limonite.
This study confirmed the feasibility of natural limonite working as the iron catalyst for the PNP wastewater treatment in the BES-Fenton system. After the start-up period of the BES-Fenton systems, ai...
The present research work is focused on the development of an alternative microwave reductive roasting process of red mud using lignite (30.15wt.%Cfix), followed by wet magnetic separation, in order t...
Brain metal accumulation in Wilson's disease.
Brain metal accumulation is suggested in the pathogenesis of numerous neurodegenerative disorders. In Wilson's disease (WD), only copper has been examined. The aim of the present study was to evaluate...
Manganese (hydr)oxides are powerful oxidants mediating the transformation of As(III) to As(V) under natural conditions, however, the presence of Mn(II) on the oxidation of As(III) in the pH range of 7...
Silica supported hematite (Fe2O3/silica) that is more active but less stable than the supported hematite for organic photodegradation in aqueous solution has been reported. In this work, we report on...
News Articles
Twice weekly iron supplementation to pregnant women as effective as a daily regime
Daily supplementation of iron tablets to pregnant women does not provide any benefits in birth weight or improved infant growth compared to twice weekly supplementation, according to a study by intern...
MARIETTA, Ga., June 18, 2013 /PRNewswire/ -- Feosol® Iron Supplements, distributed by Meda Consumer Healthcare's US headquarters in Marietta, Georgia, has been awarded the #1 Pharmacist Recommend...
A versatile mill for universal use in laboratory and production areas This compact yet powerful mill is designed for crushing and grinding all types of materials up to the medium-hard range within a v...
Rockwell Medical Receives $20 Million in New Financing
WIXOM, MI -- (Marketwired) -- 06/18/13 -- Rockwell Medical (NASDAQ: RMTI), a fully-integrated biopharmaceutical company targeting end-stage renal disease (ESRD) and chronic kidney disease (CKD) with...
TAIPEI, Taiwan, June 17, 2013 /PRNewswire/ -- TWi Biotechnology, Inc. today announced that it has completed the patient enrollment in a phase II trial of AC-201 for Gout Flare Prophylaxis (GFP)...
PPIs and Risk of Vitamin and Mineral Deficiency
How do PPIs affect calcium, magnesium, and iron levels? Therapeutic Advances in Drug Safety
IV Iron in CKD: Understanding the Guidelines
Dr. Jeffrey Berns provides perspective on sections in the KDIGO guidelines on managing chronic kidney disease that deal with intravenous iron. Medscape Nephrology
Sugar overload can damage heart
Too much sugar can set people down a pathway to heart failure, according to a new study.
Sugar overload can damage heart, research shows
Too much sugar can set people down a pathway to heart failure, according to a study led by researchers at The University of Texas Health Science Center at Houston (UTHealth).
EHA 2013: Mini-hormone fights iron
Dr Elizabeta Nemeth presents findings of a study in patients with iron overload disorders that will contribute to the design of a potential new treatment at the 18th Congress of the European Hematolog...
Events
None
Companies
Iron Mountain Incorporated (NYSE: IRM) provides information management services that help organizations lower the costs, risks and inefficiencies of managing their physical and di...
Clinical Trials
Effects of Anemia Correction on Vascular and Monocyte Function in Renal Transplant Recipients
Correction of anaemia in renal transplant recipients by parenteral application of recombinant erythropoietin and if necessary iron will improve large artery function (endothelial function...
Iron Sucrose in Stage 3/4 Kidney Disease
One of the complications of late stage kidney disease is the development of a low red blood cell count (anaemia/low haemoglobin concentration). The Australian Commonwealth government limit...
Sickle cell disease is a life-long blood condition that can cause damage to the brain and other organs of the body. Children may develop severe, debilitating clinical states, with stroke o...
This is a multi-center open label, randomized phase-3 study with stratification according to diagnosis and baseline serum-EPO level. The correction of mild or moderate anemia and the effec...
Study for the Treatment of Transfusional Iron Overload in Myelodysplastic Patients
Thirty patients will be enrolled into this open-label, single-arm trial designed to assess the safety and tolerability of oral deferasirox in adult transfusion dependent myelodysplastic sy...
Clinical and Laboratory Investigation of Humans With Informative Iron or Erythroid Phenotypes
This study will examine blood for factors that may cause or prevent diseases involving iron or red blood cells. Iron is an important nutrient for human health that is needed to produce red...
TransMID treatment or best standard of care for patients with advanced glioblastoma multiforme Glioblastoma multiforme (GBM) is a type of brain tumour. GBM tumours are usually treated...
Cardiac Function in Patients With Hereditary Hemochromatosis
This study will examine the effect of iron buildup in the hearts of patients with hereditary hemochromatosis (HH), a genetic disease that causes the body to accumulate excess amounts of ir...
Safety and Efficacy of Doxorubicin Adsorbed to Magnetic Beads
MTC-DOX is Doxorubicin or DOX, a chemotherapy drug, that is adsorbed, or made to “stick,” to magnetic beads (MTCs). MTCs are tiny, microscopic particles of iron and carbon. When DOX...
MTC-DOX is Doxorubicin or DOX, a chemotherapy drug, that is adsorbed, or made to "stick", to magnetic beads (MTCs). MTCs are tiny, microscopic particles of iron and carbon. When DOX is a...
Videos
Iron Overload ( subtitulado espanhol)
Sobrecarga de hierro a causa de transfusiones de sangre...
Medical and Biotech [MESH] Definitions
Iron-binding Proteins
Proteins that specifically bind to IRON.
Transferrin-binding Proteins
A class of carrier proteins that bind to TRANSFERRIN. Many strains of pathogenic bacteria utilize transferrin-binding proteins to acquire their supply of iron from serum.
Bacterial Transferrin Receptor Complex
A complex of proteins that forms a receptor for TRANSFERRIN in BACTERIA. Many pathogenic bacteria utilize the transferrin-binding complex to acquire their supply of iron from serum.
Iron-regulatory Proteins
Proteins that regulate cellular and organismal iron homeostasis. They play an important biological role by maintaining iron levels that are adequate for metabolic need, but below the toxicity threshold.
Iron Regulatory Protein 1
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its RNA binding ability and its aconitate hydrolase activity are dependent upon availability of IRON.
