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Menstrual Cycle - Biotech, Pharma and Life Science Channel

10:29 EDT 19th May 2013 | BioPortfolio

PubMed Articles [ 3401 Associated PubMed Articles listed on BioPortfolio]

Total synthesis and biological evaluation of grassypeptolide a.

Herein, we describe in full our investigations into the synthesis of grassypeptolide A (1) in 17 linear steps with an overall yield of 11.3 %. In particular, this work features the late-stage intr...

A randomized, multi-center, open-label, phase II study of once-per-cycle DA-3031, a biosimilar pegylated G-CSF, compared with daily filgrastim in patients receiving TAC chemotherapy for early-stage breast cancer.

Backgrounds A pegylated form of recombinant granulocyte-colony stimulating factor (G-CSF) was developed for prophylactic use in breast cancer. The aim of this study was to evaluate the efficacy and sa...

Tetrahydrofurofuran-type lignans inhibit breast cancer-mediated bone destruction by blocking the vicious cycle between cancer cells, osteoblasts and osteoclasts.

Breast cancer frequently spreads to bone. The interaction between bone metastases and microenvironment, referred as the "vicious cycle", increases both tumor burden and bone destruction. Therefore, in...

Antiproliferative effect of two novel COX-2 inhibitors on human keratinocytes.

Selective COX-2 inhibitors (COXib) belonging to the class of diaryl heterocycles (e.g., celecoxib, rofecoxib, etc.), are devoid of the undesirable effects due to their capacity to inhibit selectively...

A catalytic asymmetric synthesis of polysubstituted piperidines using a rhodium(i)-catalyzed 2+2+2 cycloaddition employing a cleavable tether.

Break the cycle: The title reaction proceeds with a variety of alkyne substrates in good yield and high enantioselectivity. Upon reduction of the vinylogous amide in high diastereoselectivity (>19:1)...

Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma.

PURPOSE To assess pharmacodynamic effects and intrinsic and acquired resistance mechanisms of the BRAF inhibitor vemurafenib in BRAF(V600)-mutant melanoma, leading to an understanding of the mechanism...

Biologic Determinants of Tumor Recurrence in Stage II Colon Cancer: Validation Study of the 12-Gene Recurrence Score in Cancer and Leukemia Group B (CALGB) 9581.

PURPOSE A greater understanding of the biology of tumor recurrence should improve adjuvant treatment decision making. We conducted a validation study of the 12-gene recurrence score (RS), a quantitati...

The aza-morita-baylis-hillman reaction: a mechanistic and kinetic study.

The aza-Morita-Baylis-Hillman (aza-MBH) reaction has been studied in a variety of solvents, a selection of imine substrates and with various combinations of PPh3 and para-nitrophenol as the catalyst s...

Differential gene expression analysis between anagen and telogen of Capra hircus skin based on the de novo assembled transcriptome sequence.

Capra hircus, an economically important livestock, plays an indispensable role in the world animal fiber industry. In the present study, using Illumina/Solexa high throughput sequencing technology, we...

Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages.

The mycotoxin alternariol (AOH), a frequent contaminant in fruit and cereal products, is known to induce DNA damage with subsequent cell cycle arrest. Here we elucidated the effects of AOH on stages o...

News Articles [ 1170 Associated News Articles listed on BioPortfolio]

A Vicious Cycle That Helps Obesity Perpetuate Itself

With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds su...

To Increase Bicycle Use, Improve Public Health, A Change In Cycle Track Policy Needed

Bicycle engineering guidelines often used by state regulators to design bicycle facilities need to be overhauled to reflect current cyclists' preferences and safety data, according to a new study from...

Scottish women over 40 to get IVF on the NHS

Women aged up to 42 will now get a free cycle, rather than the previous maximum age limit of 40, after undergoing a test to see how many eggs they have left. This is known as their ovarian reserve....

e-MDs Partners with dashboardMD to Provide Enhanced Business Intelligence Reporting Capabilities and Turnkey Healthcare Analytics

dashboardMD, a leading provider of business intelligence reporting solutions for healthcare, announced today that it has formed a strategic partnership with e-MDs, a leading provider of electronic hea...

Oncothyreon off after Phase II data for PX-866

Oncothyreon Inc. (NASDAQ:ONTY) fell $0.64 (25%) to $1.97 on Thursday after reporting data from two Phase II trials of once-daily oral PX-866 to treat recurrent glioblastoma multiforme (GBM) and recurr...

Gene involved in neurodegeneration keeps clock running: Scientists identify another gene important to morning wake-up call

Scientists have shown a gene involved in neurodegenerative disease also plays a critical role in the proper function of the circadian clock. In a study of the common fruit fly, the researchers found t...

hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces New Weight Loss Tips to Break the Brutal Cycle of Weight Gain and Depression

Diet Doc hCG diets incorporate weight loss tips from weight management experts trying to break the vicious cycle of depression and weight gain. San Francisco, CA (PRWEB) May 16, 2013 Patients dealing...

Shaun Hadsall's 4 Cycle Solution New Diet Program Review and Secrets Revealed By Daily Gossip

Denver, Colorado (PRWEB) May 16, 2013 Daily Gossip will provide its readers with the long-sought solution for a perfectly chiseled body: Shaun Hadsall's 4 Cycle Solution program . Accordin...

FDA/PhUSE Collaboration: Study Data Reviewer’s Guide Work Package v1.1 Available

The Study Data Reviewer’s Guide Template, a creation of the FDA/PhUSE Working Group collaboration is now available. The Study Data Reviewer’s Guide documents, in a human-readable way, data life-c...

PeopleBeatingCancer Founder to Participate in Cleveland Marathon

Cancer survivor and founder of PeopleBeatingCancer, David Emerson, will hand-cycle the Cleveland Marathon to fundraise for his patient-focused non-profit. Money from sponsorships will go towards supp...

Events [0 Results]

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Companies [ 92 Associated Companies listed on BioPortfolio]

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Storwize

On July 29th, IBM announced that it has entered into a definitive agreement to acquire Storwize. The acquisition is anticipated to close in the third quarter of 2010, subject to t...

NHPN

NHPN, a national healthcare revenue cycle management company, supports hospitals and hospital owned provider organizations by offering strategic managed care solutions to drive in...

D3Publisher

D3Publisher is a video game publisher for Wii™, Nintendo DS™, the PSP® (PlayStation®Portable) system, PlayStation®2 computer entertainment system, PlayStationÂ...

GfK HealthCare

GfK HealthCare (www.gfkhc.com) is the largest provider of fully integrated custom health care marketing research in the world. With the broadest range of custom and syndicated...

Planned Systems International, Inc. (PSI)

PSI has been a leading provider of IT solutions and services to federal government and private sector organizations since 1988. With principle offices in Arlington, VA and corpora...

RemitDATA Inc. and SYNNEX Corporation

Founded in 2000, RemitDATA Inc. helps more than 75,000 healthcare providers improve revenue and cash collections by identifying and correcting performance issues in the post-adjud...

Adreima

Adreima advocates for hospitals nationwide, providing revenue cycle management services supported by a deep knowledge of state-specific issues and unparalleled in-house expertise...

3M Health Information Systems

3M Health Information Systems delivers comprehensive software and consulting services to help organizations worldwide improve documentation, quality, and financial performance acr...

ProspX, Inc.

ProspX, Inc. develops the industry leading solution for managing the complex, multi-party sales process of the $500 billion commercial insurance industry. The Software-as-a-Servic...

Clinical Trials [ 652 Associated Clinical Trials listed on BioPortfolio]

Pelvic Pain in Women With Endometriosis

This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standa...

Body Heat Content and Dissipation in Obese and Normal Weight Adults

This study will investigate how different parts of the body lose body heat and will measure the heat released by specific areas such as the limbs and abdomen. Animal studies suggest that d...

Preconception Reproductive Knowledge Promotion (PREKNOP)

This study examines the efficacy of the "Preconception Reproductive Knowledge Promotion (PREKNOP)" intervention, designed to promote women's reproductive health and positive pregnancy outc...

Optimal rhCG(Ovidrel®) Dose in Poor Responder During IVF and ICSI Cycles

Choriogonadotropin alfa (Ovidrel®) is a recombinant hCG (rhCG) preparation derived from genetically engineered Chinese hamster ovary cells, which is widely used for final oocyte maturatio...

Development of an Evaluation Method of Elderly Condition in Patient Receiving Chemotherapy Treatment

Number of elderly people over 70 is increasing in France. In 2002, in the south-west, 273,741 of them were over 75 years, i.e. 9.2% of Aquitaine population. Incidence of cancer in this old...

Anti-Estrogens - A Potential Treatment for Bipolar Affective Disorder in Women?

OBJECTIVE: To test the use of two adjunctive hormonal agents in a 28 day three-arm, double-blind, placebo-controlled study in the treatment of acute mania/hypomania. HYPOTHESIS:...

Paraplegic Cycling: Improving Health After Spinal Cord Injury

Surface electrical stimulation has for many years been widely used to retrain paralysed muscle and achieve the functions of standing and stepping. Recently a number of centres have used el...

Treatment Protocol for Relapsed Acute Promyelocytic Leukemia (APL) With Arsenic

Summary Acute promyelocytic leukemia is defined by a characteristic morphology (AML FAB M3/M3v), by the specific translocation t(15;17) and its molecular correlates (PML/RARa and RARa/PML...

Gemcitabine Plus Cisplatin Single Dose Versus Split Dose in the Treatment of Patients With Locally Advanced or Metastatic Breast Cancer After Failure of Anthracyclines and/or Taxanes

This is an open label, two arms, randomized, unblinded phase 2 study in patients with locally advanced or metastatic breast cancer who have been previously treated with anthracycline with/...

A Trial of Gemcitabine Combined With Vinorelbine as First Line Chemotherapy for Metastatic Breast Cancer

This is a Phase II study of gemcitabine- Vinorelbine combination in a 3-weekly schedule as first line chemotherapy in patients with metastatic breast cancer. Eighty patients with measurabl...

Medical and Biotech [MESH] Definitions

Spores, Protozoan

A vegetative stage in the life cycle of sporozoan protozoa. It is characteristic of members of the phyla APICOMPLEXA and MICROSPORIDIA.

Telomeric Repeat Binding Protein 1

A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues.

Telomeric Repeat Binding Protein 2

A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the cell cycle. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 1 in that it contains basic N-terminal amino acid residues.

Scyphozoa

The class of true jellyfish, in the phylum CNIDARIA. They are mostly free-swimming marine organisms that go through five stages in their life cycle and exhibit two body forms: polyp and medusa.

Hydrozoa

A class in the phylum CNIDARIA which alternates between polyp and medusa forms during their life cycle. There are over 2700 species in five orders.

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