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Optic nerve appearance - Biotech, Pharma and Life Science Channel

12:53 EDT 24th May 2013 | BioPortfolio

PubMed Articles [ 5246 Associated PubMed Articles listed on BioPortfolio]

Identification of serum microRNAs in genome-wide serum microRNA expression profiles as novel noninvasive biomarkers for malignant peripheral nerve sheath tumor diagnosis.

Recent studies found that serum microRNAs (miRNAs) could serve as stable and noninvasive biomarkers for disease diagnosis. We used genome-wide serum miRNA expression analysis to investigate the role o...

Expression changes and bioinformatic analysis of Wallerian degeneration after sciatic nerve injury in rat.

Wallerian degeneration (WD) remains an important research topic. Many genes are differentially expressed during the process of WD, but the precise mechanisms responsible for these differentiations are...

Spinal neuroimmune activation inhibited by repeated administration of pioglitazone in rats after L5 spinal nerve transection.

Neuroimmune activation contributes to the generation and maintenance of neuropathic pain after peripheral nerve injury. Peroxisome proliferator activated receptor gamma (PPAR-γ) agonists have potenti...

Capsaicin avoidance as a measure of chemical hyperalgesia in orofacial nerve injury models.

Many patients suffer from trigeminal neuralgia and other types of orofacial pain that are poorly treated, necessitating preclininal animal models for development of mechanisms-based therapies. The pre...

Transcorneal electrical stimulation alters morphology and survival of retinal ganglion cells after optic nerve damage.

Traumatic optic nerve injury leads to retrograde death of retinal ganglion cells (RGCs), but transcorneal electrical stimulation (TES) can increase the cell survival rate. To understand the mechanisms...

A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4.

Many studies have shown that minocycline, an antibacterial tetracycline, suppresses experimental pain. While minocycline's positive effects on pain resolution suggest that clinical use of such drugs m...

Femoral nerve palsy as delayed complication after total hip replacement : Delayed hematoma formation in unexpected screw malpositioning.

Nerve injury after total hip replacement is a rare but severe complication. If the nerve lesion becomes evident in the early postoperative phase the lesion is often due to an incorrect implant positio...

Chronic relapsing inflammatory optic neuropathy: a systematic review of 122 cases reported.

Chronic relapsing inflammatory optic neuropathy (CRION) is an entity that was described in 2003. Early recognition of patients suffering from CRION is relevant because of the associated risk for blind...

Generic Drugs for Hypertension: Are They Really Equivalent?

Many antihypertensive drugs are now available in generic formulations at fractions of the cost of their branded counterparts. In the United States, marketing approval for generic medications is usuall...

Phacoemulsification in anterior megalophthalmos: rhexis fixation technique for intraocular lens centration.

We describe phacoemulsification in both eyes of a patient with anterior megalophthalmos. Surgery in such cases can be challenging because of a deep anterior chamber, enlarged ciliary ring, weakened zo...

News Articles [ 1932 Associated News Articles listed on BioPortfolio]

New animal model gives insights into mechanisms of Parkinson's disease pathogenesis

In Parkinson's disease, the protein "alpha-synuclein" aggregates and accumulates within neurons. Specific areas of the brain become progressively affected as the disease develops and advances. The mec...

New Research Discusses Success of Facelift Procedures Performed in Conjunction with Parotidectomy

World-renowned head and neck surgeon Dr. Babak Larian says that it is safe and possible to perform a facelift alongside a parotidectomy in patients requiring both procedures. Beverly Hills, CA (PRWEB)...

Research findings may offer new hope to stroke victims

A study by researchers at Henry Ford Hospital found "substantial evidence" that a regenerative process involving damaged nerve fibers in the spinal cord could hold the key to better functional recover...

Researchers reveal new insights about the process of axon amputation

As the human body fine-tunes its neurological wiring, nerve cells often must fix a faulty connection by amputating an axon - the "business end" of the neuron that sends electrical impulses to tissues...

Discovery could aid research into motor neuron disease

Scientists have found that a key hormone allows young zebrafish to develop and replace their motor neurons - a kind of nerve cell found in the spinal cord.

Neuropathy Nerve Damage Can Now Be Reversed With Neuracel

Boise, Idaho (PRWEB) May 23, 2013 Diabetes is one of the worst diseases on its own, but it can become a nuisance when patients are unfortunate enough to become victims of peripheral neuropathy as w...

The secret lives (and deaths) of neurons

Researchers have uncovered surprising insights about how nerve cells rewire themselves, shedding light on a process linked with neurodegenerative diseases and neurodevelopmental disorders like schizop...

Yves Pichon’s New Book Presents Latest Neurophysiological Discoveries

UNITED KINGDOM (PRWEB) May 24, 2013 The sodium theory has been elegantly proposed by A.L. Hodkin, A.F. Huxley and B. Katz in the early 1950s, after their experiments on Plymouth squids, to accoun...

AIBioTech(R) Receives Subcontract Award From DynPort Vaccine Company LLC, for Continued Development and FDA Approval of a Nerve Agent Prophylactic

RICHMOND, Va., May 23, 2013 (GLOBE NEWSWIRE) -- AIBioTech is pleased to announce receipt of a firm fixed price subcontract from DynPort Vaccine Company LLC (DVC), a CSC company, valued at nearly $3 m...

Researchers Develop Model For Better Testing, Targeting Of MPNST

Researchers from the Masonic Cancer Center, University of Minnesota, and the University's Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors (MPNST) that...

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Companies [ 33 Associated Companies listed on BioPortfolio]

Integra Telecom Inc.

Integra Telecom Inc. provides integrated communications services across 33 metropolitan areas in 11 Western states, including: Arizona, California, Colorado, Idaho, Minnesota, Mon...

Alaska Communications Systems Group, Inc.

Headquartered in Anchorage, Alaska Communications Systems Group, Inc. (“ACS”) (NASDAQ:ALSK), through its subsidiaries, provides Alaska Communications services and is Ala...

Impulse Monitoring, Inc. (IMI)

Impulse Monitoring, Inc. (IMI) provides surgical support services to hospitals and other facilities that includes intraoperative neuromonitoring (IONM) for spinal, nerve and brain...

CerebralRx

Based in Yehud, Israel, CerebralRx was founded in 2010 as a spin-off of BioControl Medical to develop breakthrough implantable neuromodulation systems for the treatment of autonom...

DigitalOptics Corporation

DigitalOptics Corporation, a wholly owned subsidiary of Tessera Technologies, Inc. (NASDAQ: TSRA), delivers innovation in imaging and optics with products and capabilities that en...

Axonia Medical

Axonia Medical is a privately owned-company located in Kalamazoo MI, founded by the University of Pennsylvania, Dr. Douglas H. Smith, The Robert A. Groff Endowed Professor and Vic...

Cerbomed GmbH

Cerbomed is an innovative medical device company located in Erlangen, Germany, that focuses on neuromodulation. The company, founded in 2005, focuses on transcutaneous Vagu...

RST Global Communications, LLC

Based in Shelby, North Carolina, RST Global Communications, LLC (RST), www.rstfiber.com, is a member-owned company formed in 2009 to construct and manage state-of-the-art all fibe...

NeuroMetrix, Inc.

NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...

Tomophase Corporation

Tomophase Corporation is a privately held opto-medical device company with a proprietary position in real-time, high resolution, cross sectional tissue imaging using a variant of...

Clinical Trials [ 673 Associated Clinical Trials listed on BioPortfolio]

USG Nerve Blocks for ACL Reconstruction

Anterior cruciate ligament reconstruction is a routine surgical procedure. Traditional femoral/sciatic block combinations effectively reduce postoperative pain, but results in considerable...

Direct Stimulation Of Spinal Nerve Roots To Determine Sensory And Motor Innervation Patterns

The purpose of this study is to collect data while monitoring muscles and nerves during spine surgery. The data being collected and analyzed will be used to learn more about how the body's...

A Study to Compare the Ultrasound-guided Fascia Iliaca Compartment Block (FICB) to Surgeon-placed Fascia Iliaca Compartment Block for Post-operative Pain Control in Patients Undergoing an Anterior Hip Replacement Surgery.

Surgical trauma causes nerve sensitization leading to amplification and prolongation of postoperative pain. In experimental studies, pre-injury neural blockade using local anesthetics has...

Research Study Examining Nerve Block for Migraine

Migraine and the skin sensitivity that accompanies it can go away in minutes after a nerve block, which is a procedure involving an injection of a small amount of a local anesthetic next t...

Sacral Nerve Stimulation Therapy for the Treatment of Chronic Fecal Incontinence

Fecal incontinence (FI) is a difficulty in storing gas, liquid stool or solid stool (bowel movement) in order to expel it at a proper time and place. Patients who suffer from FI may exper...

Treatment for Cubital Tunnel Syndrome

The researchers want to find out the best treatment for cubital tunnel. The researchers establish the degree of nerve compression and then the patients are randomised to different treatmen...

Control Strategies of the Locomotor System During Obstacle-Crossing in Stroke Patients

Tripping over obstacles is one of the common movements in daily life and is the most frequently mentioned cause of falls in the elderly. Indeed, crossing obstacles is a more complex motor...

Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins.

To address the following issues: (1) the course of small nerve fiber degeneration in type 2 diabetic patients, especially in asymptomatic patients; (2) the influence of blood sugar control...

Ocular Blood Flow in Early Glaucoma Patients Before and After Treatment With Dorzolamide

Impaired ocular blood flow is an important risk factor in the pathogenesis of primary open angle glaucoma (POAG). A few studies suggest that topical dorzolamide 2% may increase optic nerve...

Quality of Life Among Breast Reduction Patients

Despite the growing evidence showing that breast hypertrophy is associated with reduced Health-Related Quality of Life (HRQL) and that reduction mammoplasty has a significant positive impa...

Videos

Optic Nerve Fibers

A normal optic nerve is made up of more than a million nerve fibers. With glaucoma, as the optic nerve is damaged, it loses nerve fibers and changes in appea...

Medical and Biotech [MESH] Definitions

Amphipoda

An order of mostly marine CRUSTACEA containing more than 5500 species in over 100 families. Like ISOPODA, the other large order in the superorder Peracarida, members are shrimp-like in appearance, have sessile compound eyes, and no carapace. But unlike Isopoda, they possess thoracic gills and their bodies are laterally compressed.

Isopoda

One of the largest orders of mostly marine CRUSTACEA, containing over 10,000 species. Like AMPHIPODA, the other large order in the superorder Peracarida, members are shrimp-like in appearance, have sessile compound eyes, and no carapace. But unlike Amphipoda, they possess abdominal pleopods (modified as gills) and their bodies are dorsoventrally flattened.

Receptor, Ephb2

An eph family receptor found widely expressed in embryonic and adult tissues. High levels of EphB2 receptor are observed in growing AXONS and NERVE FIBERS. Several isoforms of the protein exist due to multiple alternative mRNA splicing.

Ephrin-a3

A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin with a high affinity for the EPHA3 RECEPTOR; EPHA5 RECEPTOR; EPHA6 RECEPTOR; EPHA7 RECEPTOR; and EPHA8 RECEPTOR. It is found primarily in NERVE TISSUE.

Nerve Fibers, Unmyelinated

A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the unmyelinated nerve fibers are small. The axons to SCHWANN CELLS ratio is greater in the unmyelinated nerve fibers than that in the myelinated fiber (NERVE FIBERS, MYELINATED) which is 1:1. Usually several axons are surrounded by a single Schwann cell in the unmyelinated nerve fibers. Therefore, each unmyelinated fiber is not completely covered by the MYELIN SHEATH formed by the Schwann cell. Unmyelinated nerve fibers conduct impulses at low velocities. They represent the majority of peripheral sensory and autonomic fibers. They are also found in the spinal cord and brain.

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