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Raynaud's Syndrome - Biotech, Pharma and Life Science Channel

08:05 EST 24th January 2017 | BioPortfolio

PubMed Articles [4988 Associated PubMed Articles listed on BioPortfolio]

Clinical assessment and train-of-four measurements in critically ill patients treated with recommended doses of cisatracurium or atracurium for neuromuscular blockade: a prospective descriptive study.

Despite few studies, a monitoring of a neuromuscular blockade with a train of four (TOF) is recommended in intensive care unit (ICU). Our objective was to compare the results of ulnar and facial TOF m...

A Validation Study of the International Consensus Diagnostic Criteria for Neuroleptic Malignant Syndrome.

Neuroleptic malignant syndrome requires prompt recognition for effective management, but there are no established diagnostic criteria. This is the first validation study of recently published internat...

Methotrimeprazine-Associated Stevens-Johnson Syndrome in 2 Ashkenazi Jewish Patients.

The Curves Exercise Suppresses Endotoxemia in Korean Women with Obesity.

Obesity and metabolic syndrome is a worldwide pandemic and associated with high cardiovascular risk. Metabolic endotoxemia (ME) is thought to be an underlying molecular mechanism. It triggers toll-lik...

Major Disease Prevalence and Menstrual Characteristics in Infertile Female Korean Smokers.

We investigated the prevalence of smoking and factors associated with smoking in infertile Korean women. Smoking status, education, occupation, personal habits, past medical history, current illness, ...

Cushing's syndrome managed by endoscopic ultrasound-guided radiofrequency ablation of adrenal gland adenoma.

Changes and role evaluation of TNF-α and IL-1β in lung tissues of ARDS mice.

Objective To study the expression levels of TNF-α and IL-1β in the lung tissues of acute respiratory distress syndrome (ARDS) mice and their relationships with the severity of lung injury in the mic...

Loss of the transforming growth factor-β effector β2-Spectrin promotes genomic instability.

Exposure to genotoxins such as ethanol-derived acetaldehyde leads to DNA damage and liver injury and promotes the development of cancer. We report here a major role for the transforming growth factor ...

Incorporating Persistent Pain in Phenotypic Frailty Measurement and Prediction of Adverse Health Outcomes.

Frailty, a syndrome of physiological deficits, is prevalent among older adults and predicts elevated risk of adverse health outcomes. Although persistent pain predicts similar risk, it is seldom consi...

A regenerative anemia in infants: 2 cases of Pearson´s syndrome.

Anemia is very common in infants. Although its causes are usually not severe and treatable, proper etiologic diagnosis should be established. When anemia is non-regenerative, it can be caused by aplas...

News Articles [1369 Associated News Articles listed on BioPortfolio]

Actelion’s PAH drug fails to meet primary objective in Phase III study

A Phase III study evaluating Actelion's macitentan in patients with pulmonary arterial hypertension (PAH) due to Eisenmenger Syndrome failed to meet its primary goal.

Short Bowel Syndrome Market be Worth US$2.6 Billion by 2024: Rising Initiatives and Awareness Drives Shed Light on Treatment With Effective Drugs, Notes TMR

ALBANY, New York, January 24, 2017 /PRNewswire/ -- The competitive landscape of the Global Short Bowel Syndrome Market is quite consolidated with Shire Plc. holding about 50% share in th...

ProMetic's PBI-4050 receives promising innovative medicine designation from the UK MHRA for the treatment of Alström Syndrome

LAVAL, QC, Jan. 24, 2017 /PRNewswire/ - ProMetic Life Sciences Inc. (TSX: PLI) (OTCQX: PFSCF), ("ProMetic" or the "Corporation") announced today that its orally active lead drug candidate, PBI-40...

IDMA Meet: Trump, Protectionism, New Markets And Cricket

The Trump presidency and the threat of protectionism, new generic opportunities beyond the US market, and the need for new...   

Drug delivery company Zynerba nets $47mm in FOPO

Zynerba Pharmaceuticals Inc. (synthetic cannabinoid therapeutics for transdermal delivery) netted $47.4mm in a follow-on public offering of 2.8mm common shares at $18. The company will use the procee...

GSK US Pharma President Jack Bailey On A “Dynamic” 2017

With new US President Trump in place, new corporate CEO Walmsley to take the reins in April and the opportunity...    

Actelion weathers Phase III Eisenmenger miss

Actelion Ltd. (SIX:ATLN) said Opsumit macitentan missed the primary endpoint in the Phase III MAESTRO trial to treat pulmonary arterial hypertension (PAH) due to Eisenmenger syndrome, a congenital hea...

Pediatric Neuropsychology Program at NYU Lutheran Helps Children Develop into Healthy Adults

BROOKLYN, N.Y., Jan. 23, 2017 /PRNewswire-USNewswire/ -- Adding further to its expanding scope of pediatric and neurological services, NYU Lutheran Medical Center is now making it easier for families ...

How To Get Ahead In The Trendy World Of Immuno-Oncology

With basic research in immuno-oncology still very limited, there are still a lot of opportunities to develop new breakthrough therapies...   &

Therabron Therapeutics Receives Orphan Drug Designation in the European Union for CG367, Indicated for the Treatment of Bronchiolitis Obliterans Syndrome

ROCKVILLE, Md., Jan. 23, 2017 /PRNewswire/ -- Therabron Therapeutics, Inc., a clinical-stage biotechnology company dedicated to advancing a new standard in respiratory care, today announced that ...

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Companies [55 Associated Companies listed on BioPortfolio]

XenoPort

We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

Velicept Therapeutics, Inc.

Velicept Therapeutics, Inc. is a privately held, clinical development company focused on advancing best-in-class compounds with the potential to fill unmet medical needs. Its lead...

Alexion Pharmaceuticals Inc.

Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion developed ...

PeterGreenlaw.com

Peter Greenlaw is a renowned health and wellness expert, researcher, speaker and co-author of "Your Third Brain: The Revolutionary Discovery to Achieve Optimal Health," "TDOS Synd...

Sensory NeuroStimulation Inc.

Based in San Clemente, Calif., the privately held Sensory NeuroStimulation Inc. was formed in 2009 after the company’s CEO, Fred Burbank, M.D., began experiencing RLS and sou...

Newron Pharmaceuticals S.p.A.

Newron (SIX: NWRN) is a biopharmaceutical company focused on the development of novel therapies for patients with diseases of the central nervous system (CNS) and pain. The Compan...

LYSOGENE

LYSOGENE is a clinical stage biotechnology company committed to the development and commercialization of innovative therapies for patients affected with rare disorders and high un...

Newron Pharmaceuticals SpA

Newron Pharmaceuticals SpA is a clinical stage biopharmaceutical company focused on the discovery and development of small molecule drugs for the treatment of central nervous system (CNS) diseases. Ou...

Tenax Therapeutics, Inc.

Tenax Therapeutics, Inc. (formerly Oxygen Biotherapeutics) is a specialty pharmaceutical company focused on developing and commercializing a portfolio of products for the critical...

Ideal Protein

Ideal Protein is a medical weight loss program that was developed 23 years ago by physician Dr. Tran Tien Chanh. Ideal Protein is a medical solution protocol based on validated sc...

Clinical Trials [2881 Associated Clinical Trials listed on BioPortfolio]

Buprenorphine Dose Adjustments and Gestational Age

In this retrospective cohort study, we plan to examine the relationship between buprenorphine dose adjustments, gestational age, urine buprenorphine levels and the rate of neonatal abstine...

Study of Iguratimod in Sjögren's Syndrome

A single-center, self-control, open-label study of efficacy and safety of Iguratimod in patients with Sjögren's Syndrome

Diagnosis of Bladder Pain Syndrome / Interstitial Cystitis

To identify new, simple and reliable biomarkers for bladder pain syndrome/interstitial cystitis (BPS/IC) for diagnosis of this disease.

Severe ARDS: Generating Evidence

An assessment of early management of moderate-severe ARDS in the United States, including ventilator management and use of rescue therapy.

Mobile Health Strategies for Veterans

The purpose of this study is to determine whether text messages/messaging (TM) or a mobile application (app), compared with an educational website-control provided to all Veterans, can imp...

Physical Activity Intervention for Patients With Reduced Physical Performance After Acute Coronary Syndrome

RATIONALE and AIM OF THE STUDY Patients with low functional capacity (frail patients) with cardiovascular disease, in particular those undergoing invasive procedures or suffering from cor...

Serum Endocan Levels in Polycystic Ovary Syndrome

In this study the investigators aimed to investigate whether there is a relation between polycystic ovary syndrome and serum endocan levels.

Safety and Efficacy of ANX-042 in Human Cardiorenal Syndrome

The purpose of this study is to look at kidney function and hormonal function in patients with a history of heart failure and kidney dysfunction, and to see how the use of a new drug, ANX-...

A Phase 2/3 Trial of the the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINAL

This international, multi-center, Phase 2/3 trial will study the safety, tolerability, and efficacy of bardoxolone methyl in qualified patients with Alport syndrome. The Phase 2 portion of...

Protocolized Sedative Weaning VS. Usual Care in Pediatric Critically Ill, RCT

Sedative and analgesic agents are widely used in the ICU. These agents can provide hypnotic effect, pain alleviation, cooperation, and synchronizing ventilatory support. Prolonged use of t...

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Medical and Biotech [MESH] Definitions

An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.

A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.

A selective adrenergic alpha-1 antagonist used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention.

A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.

A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.

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