Raynaud's Syndrome - Biotech, Pharma and Life Science Channel

23:06 EST 31st January 2015 | BioPortfolio

PubMed Articles [5224 Associated PubMed Articles listed on BioPortfolio]

Pediatric lupus: varied haematological picture and presentation.

Systemic lupus erythematosus (SLE) is a chronic, multisystem, autoimmune disease characterized by periods of increased disease activity caused by inflammation of blood vessels and connective tissue. P...

Infantile Acute Monoblastic Leukemia with MLL Gene Rearrangements.

A 7 month infant presented with fever and breathlessness with raised total counts. Examination revealed 90 % blasts with prominent nucleoli. Flow cytometry revealed a tight cluster in the monocytic ...

Vulvodynia.

Vulvodynia is a genital pain syndrome occurring in 7% to 8% of women. Although common, most practitioners are uncomfortable with the diagnosis and management of these women's pain, and many believe th...

Analysis of AGG interspersion of the FMR1 gene in fragile X syndrome.

OBJECTIVE To analyze (CGG)n repeats sequence and AGG interspersion correlated with unstable expansion of FMR1 gene in a general Chinese population. METHODS AmplideX FMR1 PCR Kit was used to amplify 38...

Prenatal diagnosis of a case of Pallister-Killian syndrome.

OBJECTIVE To study the clinical and genetic characteristics of Pallister-Killian syndrome and improve the diagnosis for this rare chromosomal disease. METHODS Standard G-banding was carried out for th...

Clinical and genetic study of a family affected with spinocerebellar ataxia 3 and polycystic kidney disease.

OBJECTIVE To investigate clinical features and genetic mutations of a family affected with spinocerebellar ataxia 3 and polycystic kidney disease. METHODS Polymerase chain reaction and DNA sequencing ...

Construction and analysis of recombinant eukaryotic expression plasmids for SOX10, the causative gene of Warrdenburg syndrome.

OBJECTIVE To study the exogenous expression and subcellular localization of wild type (WT) and mutant SOX10 proteins in vitro through generation of expression plasmids in order to reveal the pathogene...

Trends in Standard Workup Performed by Pediatric Subspecialists for the Diagnosis of Adolescent Polycystic Ovary Syndrome.

The purpose of this study is to identify trends in the clinical workup, diagnosis, and treatment of polycystic ovary syndrome by pediatric endocrinologists, pediatric gynecologists, and adolescent med...

The nocebo effect might affect treatment expectations in patients with burning mouth syndrome.

Fluid Management With a Simplified Conservative Protocol for the Acute Respiratory Distress Syndrome*

In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a low...

News Articles [1262 Associated News Articles listed on BioPortfolio]

Premenstrual Syndrome Therapeutic Pipeline Review H1 2015 Market Research Report at ReportsnReports.com

ReportsnReports.com adds “Premenstrual Syndrome - Pipeline Review, H1 2015” to its store. The report provides an overview of the Premenstrual Syndrome’s therapeutic pipeline. Dallas, TX (PRWEB) ...

Eculizumab approved by NICE

The National Institute for Health and Care Excellence approved the use of eculizumab (Soliris) for the treatment of atypical haemolytic uraemic syndrome (aHUS) for NHS patients in England on 27 Januar...

Growing Heart Cells For Epilepsy Patients

Researchers use pluripotent stem cells from patients with Dravet syndrome, differentiated into cardiomyocytes, to study potential causes of SUDEP. Medscape Neurology

ACS: A Possibly Lethal Complication of Hip Arthroscopy

Abdominal compartment syndrome is a rare but serious complication of arthroscopic hip surgery. What steps are necessary to manage it promptly? Journal of Medical Case Reports

Women with polycystic ovary syndrome admitted to hospital twice as often, study finds

Women with polycystic ovary syndrome (PCOS) have more than twice the number of hospital admissions unrelated to obstetric problems or injury compared with women without the condition, a retrospective....

What exactly is coronavirus?

The conflicts in Syria and Iraq are straining public health systems and public health efforts meant to prevent and detect the spread of infectious diseases. This is generating a "perfect storm" of con...

Thoughts on Corcept Therapeutics' (CORT) Update

On Thursday, January 29, 2015, Corcept Therapeutics reported Q4 and FY 2014 revenue and held a conference call. In sum, we were treated to a positive outlook, more than we had previously anticipated.&...

Ending Isolation and Stigma Couldn't be Easier at NJ Walks for Tourette Syndrome at Princeton

Princeton Junction, NJ, January 30, 2015 --(PR.com)-- To look at the Kowalski family of Plainsboro, it's apparent that they make each other happy. Tim and Leslie are never far from a smile when t...

Angelman syndrome-associated ubiquitin ligase UBE3A/E6AP mutants interfere with the proteolytic activity of the proteasome

Novel mutations in the PNPLA6 gene in Boucher-Neuhäuser syndrome

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Companies [48 Associated Companies listed on BioPortfolio]

Tenax Therapeutics, Inc.

Tenax Therapeutics, Inc. (formerly Oxygen Biotherapeutics) is a specialty pharmaceutical company focused on developing and commercializing a portfolio of products for the critical...

Ideal Protein

Ideal Protein is a medical weight loss program that was developed 23 years ago by physician Dr. Tran Tien Chanh. Ideal Protein is a medical solution protocol based on validated sc...

Cortendo AB

Cortendo AB is a biopharmaceutical company headquartered in Göteborg, Sweden. Its stock is publicly traded on the NOTC-A-list (OTC) in Norway. Cortendo is a pioneer in the fiel...

Innocrin Pharmaceuticals, Inc.

Innocrin discovers and develops novel, best-in-class oral inhibitors of CYP17 lyase, a validated enzyme target for the treatment of castration-resistant prostate cancer. VT-464 an...

Sea-licious™

Karlene Karst, a Registered Dietician, is a leading health specialist in both nutrition and natural medicine. She is the co-author of the national best seller “Healthy ...

Synergy Pharmaceuticals Inc.

Synergy Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development of new drugs to treat patients with gastrointestinal (GI) diseases and disorders. Synergyâ...

Sturge-Weber Foundation

Since its founding in 1987, the Sturge-Weber Foundation (SWF) has provided information, education and friendly support to adults and families of children with Sturge-Weber syndrom...

Horizon Science

Horizon Science is an Australian-based company that develops natural innovative sugar cane molasses extracts enriched with polyphenols for health benefits in blood glucose managem...

Nathealth Solutions

Nathealth Solutions is the U.S.-based distributor of BergaMet MEGA, the most powerful, natural agent for the management of lipid disorders. Derived from the Citrus bergamia Risso ...

Ironwood Pharmaceuticals, Inc. and Bionomics Limited

Ironwood Pharmaceuticals (NASDAQ: IRWD) is an entrepreneurial pharmaceutical company dedicated to the art and science of great drugmaking. Linaclotide, Ironwood’s GC-C agonis...

Clinical Trials [1906 Associated Clinical Trials listed on BioPortfolio]

Blood Cell Response to Exercise

Moderate exercise is recommended to improve cardiovascular health in obese and overweight people particularly with metabolic syndrome (MetS) that have hypertension, elevated fasting blood ...

Ph 2 Trial to Evaluate Safety & Efficacy of RM-493 in Obese Patients With Prader-Willi Syndrome

The purpose of this study is to evaluate the effects of a once daily subcutaneous (SC) injectable formulation of RM-493 in obese subjects with Prader-Willi syndrome on tolerability, weight...

Phase II Hedgehog Inhibitor for Myelodysplastic Syndrome (MDS)

This study is being done to see how safe an investigational drug is and test how well it will work to help people with refractory/relapsed myelodysplastic syndrome (MDS) or chronic myelomo...

Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies

Whole blood samples will be collected from high-risk pregnant women to validate the clinical performance of the SEQureDx Trisomy 21 Test.

Gene Therapy for WAS

This is a phase I/II study to evaluate the safety and efficacy of Hematopoietic Stem Cell genetherapy for the Wiskott-Aldrich Syndrome.

Study of MLN9708 as Maintenance Therapy for Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) in Remission

The goal of this clinical research study is to learn if ixazomib can prevent AML or MDS from coming back in patients who are in remission. The safety of this drug will also be studied.

Safety Study of TPI-287 to Treat CBS and PSP

The purpose of this study is to determine the safety and tolerability [maximum tolerated dose (MTD) within planned dosing range] of intravenous (IV) infusions of TPI 287 administered once ...

Sodium Oxybate in Patients With Chronic Fatigue Syndrome.

Chronic fatigue syndrome (CFS) is a disabling, unexplained disorder characterized by physical and mental exhaustion. Complaints of disturbed and unrefreshing sleep are very common in CFS p...

Uncertain Genetic Test Results for Lynch Syndrome

Background: - Individuals have varying tolerances for receiving ambiguous information. However, not much is known about how ambiguous genetic testing information is received. Also...

Iron Overload and Transient Elastography in Patients With Myelodysplastic Syndrome

Patients with myelodysplastic syndrome (MDS) have an ineffective hemopoiesis and often suffer from anemia. This can lead to red blood cell transfusion dependency and iron overload. Iron ov...

Medical and Biotech [MESH] Definitions

An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.

A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.

A selective adrenergic alpha-1 antagonist used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention.

A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.

A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.

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