Raynaud's Syndrome - Biotech, Pharma and Life Science Channel

07:27 EDT 16th September 2014 | BioPortfolio

PubMed Articles [5471 Associated PubMed Articles listed on BioPortfolio]

Impact of childhood obesity on cardiac structure and function.

Obesity prevalence is still on the rise worldwide in both adults and children. In adults, obesity is a significant cardiovascular risk factor associated with increased morbidity and mortality. In chil...

Genetic heterogeneity in Alzheimer disease and implications for treatment strategies.

Since the original publication describing the illness in 1907, the genetic understanding of Alzheimer's disease (AD) has advanced such that it is now clear that it is a genetically heterogeneous condi...

Judicious use of biologicals in juvenile idiopathic arthritis.

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disorder that may cause joint destruction. Biological treatments targeting specific cytokines and cell interactions have transformed the o...

Infectious Diseases and Tropical Disease Pathology: SY16-2B PEDIATRIC CEREBRAL MALARIA PATHOLOGY.

Malaria kills more than half a million children a year in sub-Saharan Africa despite the availability of effective combination drug therapy, efficacy of bed nets, and environmental control measures. C...

Coexistence of psoriasis, and alopecia areata with trachyonychia in a pediatric patient with Turner Syndrome.

Turner syndrome is a genetic disorder characterized by abnormalities of the X chromosome. An association with many autoimmune diseases is described as well as skin diseases such as psoriasis, vitiligo...

Extramedullary relapse of acute linfoblastic leukemia: report of a case.

The superior vena cava syndrome (SVCS) is considered an emergency and requires immediate treatment; therefore, the etiologic diagnosis is essential before deciding on its implementation. The managemen...

Biotinidase deficiency and vascular ring malformation: case report.

Biotinidase deficiency is an autosomal recessive metabolic disorder that affects the cleavage of biotin. Family studies of the index case found that both parents are usually carriers and siblings have...

Autonomic failure in CANVAS syndrome.

Renal Pathology: SY23-2 HYPOCOMPLEMENTEMIC URTICARIAL VASCULITIS SYNDROME - A CASE REPORT.

Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a rare immune-complex small vessel systemic vasculitis involving kidney in about 50% of patients. Characteristic clinical features are recur...

Renal Pathology: SY23-2 A CASE OF A NEW DISEASE ENTITY: PODOCYTIC INFOLDING GLOMERULOPATHY.

A 41-year-old woman was discovered to have enteric infection of Aeromonas caviae and was treated with antibiotics. Subsequently she developed nephrotic syndrome. Renal biopsy showed a non-argentaffine...

News Articles [1502 Associated News Articles listed on BioPortfolio]

NovaBay Pharmaceuticals Will Feature i-Lid Cleanser for the First Time at Vision Expo West

The world’s most important meeting on eye care offers a major opportunity for NovaBay to explain the successful use of i-Lid Cleanser for the management of serious common eye co...

My Pain Cream MD Now Offering Customized Prescription Pain Creams for Those with Failed Back and Neck Surgery Syndrome

My Pain Cream MD, the leading supplier of prescription pain creams for all types of pain conditions, is now offering the customized topical creams for those suffering from failed back or neck surgery...

Bovine Immunoglobulin Protein Isolates For The Nutritional Management Of Enteropathy

Entera Health, Inc. Announces the Publication of a Scientific Article Summarizing Preclinical and Clinical Studies Evaluating the Ability of Serum- or Plasma-Derived Protein Preparations to Promote In...

Physician Improves Upon His Proven & Patented Dry Eye Syndrome Formula with Dry Eye Relief® TG-1000

HUNTINGTON, N.Y., Sept. 16, 2014 /PRNewswire/ -- The 30+ million American adults who struggle with the stinging, eye watering, light sensitivity and itchiness of Dry Eye Syndrome now have a new w...

Alternative medicine: There should only be one standard

“Doctor, what do you think of alternative medicine?” a patient with chronic fatigue syndrome asked me the other day. She was interested in doing something more for her severe fatigue. “Would acu...

Novavax, U. of Maryland report positive preclinical results for MERS vaccine

With the arrival of Middle East respiratory syndrome coronavirus in the U.S. and a rising death toll in Saudi Arabia, a vaccine designed by Novavax ($NVAX) and the University of Maryland has shown pro...

Jacobsen Syndrome, Autism Linked

A rare genetic disorder known as Jacobsen syndrome has been linked with autism, according to a recent joint investigation by researchers at San Diego State University and the University of California,...

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

Scott Canna and colleagues report the identification of a de novo mutation in a conserved region of NLRC4 by whole-exome sequencing of an individual presenting with macrophage activation syndrome. Fun...

Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

Richard Lifton, Barbara Kazmierczak and colleagues report the identification of a new enterocolitic and autoinflammatory syndrome, which they find is caused by de novo gain-of-function mutations affec...

HCW ups Catalyst Pharma price target to $13

H.C. Wainwright has raised its price target for “buy-rated” Catalyst Pharmaceutical Partners (NASDAQ:CPRX) to $13 from $5. The stock closed at $3.09 on Friday. Catalyst’s lead program, Firda...

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Companies [44 Associated Companies listed on BioPortfolio]

Sea-licious™

Karlene Karst, a Registered Dietician, is a leading health specialist in both nutrition and natural medicine. She is the co-author of the national best seller “Healthy ...

Synergy Pharmaceuticals Inc.

Synergy Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development of new drugs to treat patients with gastrointestinal (GI) diseases and disorders. Synergyâ...

Sturge-Weber Foundation

Since its founding in 1987, the Sturge-Weber Foundation (SWF) has provided information, education and friendly support to adults and families of children with Sturge-Weber syndrom...

Horizon Science

Horizon Science is an Australian-based company that develops natural innovative sugar cane molasses extracts enriched with polyphenols for health benefits in blood glucose managem...

Nathealth Solutions

Nathealth Solutions is the U.S.-based distributor of BergaMet MEGA, the most powerful, natural agent for the management of lipid disorders. Derived from the Citrus bergamia Risso ...

Ironwood Pharmaceuticals, Inc. and Bionomics Limited

Ironwood Pharmaceuticals (NASDAQ: IRWD) is an entrepreneurial pharmaceutical company dedicated to the art and science of great drugmaking. Linaclotide, Ironwood’s GC-C agonis...

Shionogi & Co., Ltd.

Headquartered in Osaka, Japan, Shionogi & Co., Ltd. is a major research-driven pharmaceutical company dedicated to placing the highest value on patients. Shionogi’s Research ...

Akebia Therapeutics, Inc.

Akebia Therapeutics is a discovery and development company focused on anemia and vascular disorders. Akebia’s lead program, AKB-6548, an orally bioavailable HIF-prolyl hydrox...

Aviir, Inc.

Founded in 2005 by cardiologists and researchers from the Stanford University School of Medicine , Aviir is focused on the discovery, development and commercialization of innovati...

AltheRx Pharmaceuticals

Formed in 2010, AltheRx Pharmaceuticals is a privately held development company whose business model is to advance projects through clinical development and create partnerships wi...

Clinical Trials [1807 Associated Clinical Trials listed on BioPortfolio]

Pre-Transplant 5-Azacitidine In Patients With High-Risk Myelodysplastic Syndrome Who Are Candidates For Allogeneic Hematopoietic Cell Transplant

The purpose of this study is to find out if treating people who have high-risk myelodysplastic syndrome (MDS) with 5-Azacitidine (Vidaza) prior to their allogeneic hematopoietic cell trans...

Efficacy of Minoxidil in Children With Williams-Beuren Syndrome

The Williams-Beuren syndrome (WBS) is a sporadic congenital disorder characterized by a multisystem developmental impairment. This syndrome is caused by a microdeletion in chromosome 7q11....

Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome

Marfan syndrome is an inherited connective tissue disorder with morbidity and mortality from aortic dilation and dissection. The degree of aortic dilation and response to beta-blockade (s...

Nicotine Patches in Reducing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine For Metastatic Breast Cancer

RATIONALE: Nicotine patches may reduce hand-foot syndrome in patients receiving capecitabine for metastatic breast cancer. It is not yet known which nicotine patch regimen may be more effe...

Randomized Study of ON 01910.Na in Refractory Myelodysplastic Syndrome Patients With Excess Blasts

The primary objective of this study is to compare overall survival (OS) in patients receiving ON 01910.Na + best supportive care (BSC) to OS of patients receiving BSC in a population of pa...

MAESTRO-OL: Macitentan in Eisenmenger Syndrome To Restore Exercise Capacity (Open-Label)

Long-term study to evaluate if macitentan is safe, tolerable and efficient enough to be used for treatment of Eisenmenger syndrome.

Safety and Pharmacokinetics of Ifetroban in Hepatorenal Syndrome Patients

Cumberland Pharmaceuticals Inc. (CPI) is developing ifetroban for treatment of hepatorenal syndrome (HRS) and proposes to conduct a study in hospitalized adult patients with HRS to assess...

Development of a Blood Test for Marfan Syndrome

The objective of this study is to determine whether a simple blood test can be a useful clinical tool for monitoring aortic disease in Marfan syndrome and Marfan-related disorders.

The Use of Heliox in Obstructive Sleep Apnea Syndrome

The goals of the project is to evaluate the effects of Heliox therapy on obstructive sleep apnea syndrome (OSAS).

Tart Cherry, Metabolic Syndrome, and Cardiovascular Risk

The hypothesis of this study is that the daily consumption of 480 ml tart cherry juice for twelve weeks will improve blood pressure and arterial stiffness by improving endothelial-mediated...

Medical and Biotech [MESH] Definitions

An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.

A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.

A selective adrenergic alpha-1 antagonist used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention.

A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.

A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.

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