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Raynaud's Syndrome - Biotech, Pharma and Life Science Channel

04:13 EDT 28th March 2017 | BioPortfolio

PubMed Articles [4975 Associated PubMed Articles listed on BioPortfolio]

Clinical assessment and train-of-four measurements in critically ill patients treated with recommended doses of cisatracurium or atracurium for neuromuscular blockade: a prospective descriptive study.

Despite few studies, a monitoring of a neuromuscular blockade with a train of four (TOF) is recommended in intensive care unit (ICU). Our objective was to compare the results of ulnar and facial TOF m...

Expansion of the phenotypic spectrum in three families of methyl CpG-binding protein 2 duplication syndrome.

The methyl CpG-binding protein 2 duplication syndrome (OMIM #300260) is characterized by hypotonia, developmental delay, spasticity, seizures, and recurrent infections. It is fully penetrant in males ...

Chemotherapy-related acute respiratory distress syndrome in germ cell tumors: a literature review.

Germ cell tumors (GCTs) are one of the more curable solid cancers in men. Approximately 8500 men are diagnosed with GCTs in the USA. The majority of patients survive due to the availability of effecti...

Locked-in Syndrome Due to Transtentorial Herniation and Kernohan Notch Phenomenon.

Key insights into the protein tyrosine phosphatase PTPN11/SHP2 associated with noonan syndrome and cancer.

Overstressed response to EIF2S3 variants in MEHMO syndrome.

Bone morphogenetic protein-2 for the treatment of congenital pseudarthrosis of the tibia or persistent tibial nonunion in children and adolescents: A retrospective study with a minimum 2-year follow-up.

There is a lack of studies reporting on rhBMP-2 application in pediatric orthopaedics, although few reports demonstrated promising results of the use of rhBMP-2 in children, especially for spine fusio...

Evaluation of the Predictive Potential of the Short Acute Retroviral Syndrome Severity Score for HIV-1 Disease Progression in Individuals With Acute HIV Infection.

A simple diagnostic scale based on the analysis and screening of clinical parameters in paediatric obstructive sleep apnoea hypopnea syndrome.

This study aimed to develop a simple and accurate method to diagnose paediatric obstructive sleep apnoea hypopnea syndrome.

Paroxysmal nocturnal haemoglobinuria in a patient with primary Budd-Chiari syndrome: a contraceptive challenge.

In this report, we describe the unique case of a 21 year-old woman, gravida 1, para 1, with paroxysmal nocturnal haemoglobinuria (PNH) and Budd-Chiari syndrome, as well as severe vaginismus and cervic...

News Articles [1363 Associated News Articles listed on BioPortfolio]

Scientists show p300 protein may stop MDS from developing into leukemia

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that p300, a protein that increases gene expression by attaching acetyl molecules to...

Severe Acute Respiratory Syndrome (SARS) - Pipeline Review, H1 2017

LONDON, March 27, 2017 /PRNewswire/ -- Severe Acute Respiratory Syndrome (SARS) - Pipeline Review, H1 2017 Summary Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline gu...

New genetic disorder named for Children's Hospital of Philadelphia team

Three scientists at Children’s Hospital of Philadelphia who identified and studied a genetic disease have been recognized by having their names attached to the disorder. An authoritative reference s...

Global Migraine market is expected to grow at 6% CAGR during 2016-2022

Key Players - Allergan, Impax Laboratories, Eisai Inc., Eli Lilly and Company, Pfizer, Inc., Johnson & Johnson, Klaria, Kowa Pharmaceuticals America,Luitpold Pharmaceuticals, Meda, Merck, " PUNE, ...

CHMP Backs Pentosan Polysulfate for Bladder Pain Syndrome

The orphan drug is for treatment of bladder pain syndrome characterized by glomerulations or Hunner's lesions in adults with moderate to severe pain, urgency and, frequency of micturition. Internati...

Synergy Pharmaceuticals Submits Supplemental New Drug Application (sNDA) for TRULANCE™ (Plecanatide) for the Treatment of Adults with Irritable Bowel Syndrome with Constipation (IBS-C)

Synergy Pharmaceuticals Inc. (NASDAQ:SGYP) announced today that the company has submitted a supplemental New Drug Application (sNDA) for TRULANCE™ (plecanatide) for the treatmen...

FDA grants orphan status to OPKO's Dravet syndrome candidate

OPKO's candidate CUR-1916, an oligonucleotide-based anti-natural antisense transcript to treat Dravet syndrome, was given orp -More- 

Neurotrope, Inc. Announces Approval for Listing on the NASDAQ Capital Market

NEW YORK, March 27, 2017 /PRNewswire/ -- Neurotrope, Inc. (OTCQB: NTRP),  a clinical-stage biopharmaceutical company developing novel therapies for neurodegenerative diseases, including Alzheimer...

White-Nose Syndrome Fungus Infects Bats in Texas

The pathogenic fungus that has decimated populations of bats throughout the eastern United States has surfaced in the state for the first time, although none of the bats appear diseased.

'Scared' father of Bangladesh 'tree girl' ends treatment

A young Bangladeshi girl diagnosed with a rare condition known as "tree man syndrome" has left hospital, her father told AFP Monday, saying he feared she would never be cured.

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Companies [57 Associated Companies listed on BioPortfolio]

MedAutonomic

MedAutonomic is a privately held medtech company dedicated to developing a bioelectric medicine to treat patients with functional diseases of the metabolic syndrome such as type-2...

Ironwood Pharmaceuticals, Inc. & Astellas Pharma Inc.

Ironwood Pharmaceuticals (NASDAQ: IRWD) is a commercial biotechnology company focused on creating medicines that make a difference for patients, building value for our fellow shar...

XenoPort

We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

Velicept Therapeutics, Inc.

Velicept Therapeutics, Inc. is a privately held, clinical development company focused on advancing best-in-class compounds with the potential to fill unmet medical needs. Its lead...

Alexion Pharmaceuticals Inc.

Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion developed ...

PeterGreenlaw.com

Peter Greenlaw is a renowned health and wellness expert, researcher, speaker and co-author of "Your Third Brain: The Revolutionary Discovery to Achieve Optimal Health," "TDOS Synd...

Sensory NeuroStimulation Inc.

Based in San Clemente, Calif., the privately held Sensory NeuroStimulation Inc. was formed in 2009 after the company’s CEO, Fred Burbank, M.D., began experiencing RLS and sou...

Newron Pharmaceuticals S.p.A.

Newron (SIX: NWRN) is a biopharmaceutical company focused on the development of novel therapies for patients with diseases of the central nervous system (CNS) and pain. The Compan...

LYSOGENE

LYSOGENE is a clinical stage biotechnology company committed to the development and commercialization of innovative therapies for patients affected with rare disorders and high un...

Newron Pharmaceuticals SpA

Newron Pharmaceuticals SpA is a clinical stage biopharmaceutical company focused on the discovery and development of small molecule drugs for the treatment of central nervous system (CNS) diseases. Ou...

Clinical Trials [2968 Associated Clinical Trials listed on BioPortfolio]

The Efficacy and Safety of the Xu-Fu-Zhu-Yu Capsule in Treatment of Qi Stagnation and Blood Stasis Syndrome.

This is a muticenter, double-blind, randomized and placebo-controled trial. the purpose of this trial is to evaluate the efficacy and safety of the Xu-Fu-Zhu-Yu Capsule in Treatment of Qi ...

Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary Therapy

The purpose of this study is to determine whether a medication, Clonidine can reduce the number of days a baby spends in the hospital and the number of days of medical treatment of withdra...

Hepatopulmonary Syndrome and Postoperative Complications After Liver Transplantation : A Case-control Study

Hepatopulmonary Syndrome is a respiratory complication of liver cirrhosis defined as a triad: hypoxemia (PaO2 < 80 mmHg in room air), chronic liver disease and intrapulmonary vasodilatatio...

The Effects of Prolonged Standing Compared to Prolonged Sitting on Postprandial Lipemia

The effects of 12 hours of prolonged standing will be compared to prolonged standing on a high fat tolerance test the following day. Plasma triglycerides, insulin, and glucose will be meas...

Small Airway Chronic Obstructive Disease Syndrome Following Exposure to WTC Dust

Many "Survivors" in the World Trade Center (WTC) clinical program have a clinical syndrome characterized by chronic obstruction in small airways and persistence of lower respiratory sympto...

Prevention of Ulinastatin on Acute Respiratory Distress Syndrome (ARDS)

Since strategies were applied in intensive care medicine, including low tidal volume ventilation, fluid resuscitation, use of antibiotics, restrictive transfusion strategy and bundle of ve...

Safety and Efficacy of TOP1630 for Dry Eye Syndrome

In subjects with Dry Eye Syndrome: The primary objective of this study is to compare the safety and tolerability of TOP1630 Ophthalmic Solution to placebo. The secondary objectives...

Circulating Androgen Levels Are Not Affected by the Administration of Vaginal Micronized Progesterone for Withdrawal Bleeding in Patients With Polycystic Ovarian Syndrome

Hormonal evaluation of women who are suspected of having Polycystic ovary syndrome (PCOS) involves the measurement of basal levels of androgens and 17-hydroxyprogesterone (17-OHP), which a...

International Congenital Central Hypoventilation Syndrome (CCHS) Registry

The Center for Autonomic Medicine in Pediatrics (CAMP) has built the first International CCHS (Congenital Central Hypoventilation Syndrome REDCap (Research Electronic Data Capture) Registr...

Brief Behavioral Treatment for Sleep Problems in IBS Study

Patients with Irritable Bowel Syndrome (IBS) often report more fatigue and sleep disturbances compared to their healthy counterparts and compared to patients with other GI disorders. This ...

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Medical and Biotech [MESH] Definitions

An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.

A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.

A selective adrenergic alpha-1 antagonist used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention.

A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.

A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.

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