Raynaud's Syndrome - Biotech, Pharma and Life Science Channel

02:22 EDT 25th October 2014 | BioPortfolio

PubMed Articles [5318 Associated PubMed Articles listed on BioPortfolio]

Dual Antiplatelet Therapy in the Anticoagulated Patient Undergoing Percutaneous Coronary Intervention Risks, Benefits, and Unanswered Questions.

A commonly encountered scenario is the patient with atrial fibrillation (AF) on oral anticoagulation (OAC) who either develops an acute coronary syndrome or has to undergo percutaneous coronary interv...

Use of Left Ventricular Support Devices During Acute Coronary Syndrome and Percutaneous Coronary Intervention.

In an effort to improve outcomes in percutaneous coronary intervention (PCI), percutaneous ventricular assist devices (PVADs) have been investigated in (1) high-risk PCI, (2) acute myocardial infarcti...

Editorial: abnormal permeability and altered mucosal serotonin metabolism in the irritable bowel syndrome - is there a link?

Obesity, Metabolic Syndrome, and Airway Disease: A Bioenergetic Problem?

Multiple studies have determined that obesity increases asthma risk or severity. Metabolic changes of obesity, such as diabetes or insulin resistance, are associated with asthma and poorer lung functi...

Total Local Anesthetic Administered Is Integral to the Syndrome of Local Anesthetic Systemic Toxicity.

Impact of childhood obesity on cardiac structure and function.

Obesity prevalence is still on the rise worldwide in both adults and children. In adults, obesity is a significant cardiovascular risk factor associated with increased morbidity and mortality. In chil...

Genetic heterogeneity in Alzheimer disease and implications for treatment strategies.

Since the original publication describing the illness in 1907, the genetic understanding of Alzheimer's disease (AD) has advanced such that it is now clear that it is a genetically heterogeneous condi...

Judicious use of biologicals in juvenile idiopathic arthritis.

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disorder that may cause joint destruction. Biological treatments targeting specific cytokines and cell interactions have transformed the o...

Prognostic utility of the soluble CD40 ligand in acute coronary syndrome.

Ulcerative colitis and Budd-Chiari syndrome: which comes first?

News Articles [1487 Associated News Articles listed on BioPortfolio]

Academy and GRAMMY Award-winner Jamie Foxx and his sister DeOndra Dixon Help Launch Down Syndrome World™ during Down Syndrome Awareness Month

Global Down Syndrome Foundation Magazine Covers Groundbreaking Research, Medical Care, and Features about People with Down Syndrome The Global Down Syndrome Foundation ...

NICE recommends Bayer's rivaroxaban as option for secondary prevention in ACS

The UK's National Institute for Health and Care Excellence (NICE) has issued its Appraisal Consultation Document (ACD) recommending Bayer HealthCare's Xarelto (rivaroxaban) 2.5mg twice daily as an opt...

Middle East respiratory syndrome coronavirus (MERS-CoV) – Turkey

On 17 October 2014, WHO EURO was notified by the National IHR Focal Point for Turkey of a laboratory-confirmed case of infection with Middle East respiratory syndrome coronavirus (MERS-CoV). On 11 Oct...

Tourette Syndrome Management Often Simple

Most patients with tics need only a handful of clinic visits, according to a new survey. The study also suggests that for some, tics continue to improve into adulthood. Medscape Medical News

Sunshine isn't slimming and can't halt diabetes

"Sunshine can make you thin," claims the Daily Mirror, while the Daily Express splashed on its front page that, "Sunlight is key to fighting diabetes". Both are strong contenders f...

Mood Disorders Linked to Lingering Concussion Effect in Kids

A personal or family history of mood disorders may be a risk factor for the postconcussion syndrome in young athletes, say authors of a case-control study. Medscape Medical News

Medical News Today: Alzheimer's-Down syndrome relationship explained

Almost all people with Down syndrome develop some signs of Alzheimer's disease. Researchers now claim to have mapped the mechanism driving this association.

Clues to genetics of congenital heart defects emerge from Down syndrome study

(Emory Health Sciences) The largest genetic study of congenital heart defects in individuals with Down syndrome found a connection to rare, large genetic deletions affecting cilia.

Researchers to Present Data on Soliris® (eculizumab) as a Treatment for Patients with aHUS at ASN 2014 Annual Meeting

Alexion Pharmaceuticals, Inc. (NASDAQ:ALXN) today announced that researchers will present seven posters detailing findings from clinical studies of Soliris® (eculizumab) in patie...

Ipsen pays $23mm up front for exclusive rights to Lexicon's Phase III carcinoid syndrome candidate

Ipsen licensed exclusive global marketing rights (outside of the US, Canada, and Japan) to Lexicon Pharmaceuticals Inc.’s telotristat, which is in Phase III trials for carcinoid syndrome.

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Companies [46 Associated Companies listed on BioPortfolio]

Innocrin Pharmaceuticals, Inc.

Innocrin discovers and develops novel, best-in-class oral inhibitors of CYP17 lyase, a validated enzyme target for the treatment of castration-resistant prostate cancer. VT-464 an...

Tenax Therapeutics, Inc.

Tenax Therapeutics, Inc. (formerly Oxygen Biotherapeutics) is a specialty pharmaceutical company focused on developing and commercializing a portfolio of products for the critical...

Sea-licious™

Karlene Karst, a Registered Dietician, is a leading health specialist in both nutrition and natural medicine. She is the co-author of the national best seller “Healthy ...

Synergy Pharmaceuticals Inc.

Synergy Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development of new drugs to treat patients with gastrointestinal (GI) diseases and disorders. Synergyâ...

Sturge-Weber Foundation

Since its founding in 1987, the Sturge-Weber Foundation (SWF) has provided information, education and friendly support to adults and families of children with Sturge-Weber syndrom...

Horizon Science

Horizon Science is an Australian-based company that develops natural innovative sugar cane molasses extracts enriched with polyphenols for health benefits in blood glucose managem...

Nathealth Solutions

Nathealth Solutions is the U.S.-based distributor of BergaMet MEGA, the most powerful, natural agent for the management of lipid disorders. Derived from the Citrus bergamia Risso ...

Ironwood Pharmaceuticals, Inc. and Bionomics Limited

Ironwood Pharmaceuticals (NASDAQ: IRWD) is an entrepreneurial pharmaceutical company dedicated to the art and science of great drugmaking. Linaclotide, Ironwood’s GC-C agonis...

Shionogi & Co., Ltd.

Headquartered in Osaka, Japan, Shionogi & Co., Ltd. is a major research-driven pharmaceutical company dedicated to placing the highest value on patients. Shionogi’s Research ...

Akebia Therapeutics, Inc.

Akebia Therapeutics is a discovery and development company focused on anemia and vascular disorders. Akebia’s lead program, AKB-6548, an orally bioavailable HIF-prolyl hydrox...

Clinical Trials [1847 Associated Clinical Trials listed on BioPortfolio]

A Non-Drug Study of The Suitability of Neurocognitive Tests And Functioning Scales For The Measurement of Cognitive And Functioning Changes in Individuals With Down Syndrome

This non-drug, longitudinal, multi-center, multi-national study will evaluate th e suitability of neurocognitive tests and functioning scales for the measurement of cognitive and functioni...

Study in Pediatric Subjects With Epilepsy

This is an open-label study to evaluate the pharmacokinetics, safety and tolerability of ezogabine/retigabine in subjects aged 12 years to less than 18 years with uncontrolled partial onse...

Treatment of Myofascial Pain Syndrome With Lidocaine Injection and Physical Therapy.

Background: Myofascial pain syndrome (MPS) of the shoulder girdle and cervical region is a common musculoskeletal problem that is often chronic or recurrent. It has demonstrated the effect...

Observational Study to Evaluate Neurodevelopmental Status in Pediatric Patients With Hunter Syndrome (MPS II)

Hunter syndrome (Mucopolysaccharidosis II, [MPS II]) is a rare, genetically linked lysosomal storage disease (LSD) caused by deficiency of the enzyme, iduronate-2-sulfatase (I2S). Most MPS...

Developing Novel Microbiota-Targeted Therapies for Irritable Bowel Syndrome

This longitudinal study is being done to understand mechanisms underlying development of irritable bowel syndrome (IBS) and the role of the gut bacteria in development of symptoms. This in...

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

This double-blind, parallel, two-arm study will evaluate the potential to reduce cardiovascular risk, the tolerability and long-term safety profile of aleglitaz ar compared to placebo on t...

Studies of Disorders in Antibody Production and Related Primary Immunodeficiency States

This study investigates gene abnormalities in Primary Immune Deficiency(PID) with a goal of improving the diagnosis and treatment of patients. The specific disorders include: 1....

Ipilimumab in Treating Patients With Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

This phase I trial studies the side effects and best dose of ipilimumab in treating patients with high-risk myelodysplastic syndrome or acute myeloid leukemia that has come back or no long...

Terlipressin + Albumin Versus Midodrine + Octreotide in the Treatment of Hepatorenal Syndrome

From 1999, several studies have showed that the use of vasoconstrictors in association with albumin are effective in the treatment of hepatorenal syndrome (HRS). The rationale of the use o...

A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)

This double-blind, randomized, placebo-controlled, multi-center study will evalu ate the safety and efficacy of dalcetrapib in patients hospitalized for an acute coronary syndrome (ACS). T...

Medical and Biotech [MESH] Definitions

An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.

A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.

A selective adrenergic alpha-1 antagonist used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention.

A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.

A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.

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