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Raynaud's Syndrome - Biotech, Pharma and Life Science Channel

04:05 EDT 18th April 2014 | BioPortfolio

PubMed Articles [4056 Associated PubMed Articles listed on BioPortfolio]

Aspirin Desensitization: Useful Treatment for Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) in Aspirin-Exacerbated Respiratory Disease (AERD)?

Aspirin intolerance syndrome is due to disturbances in the arachidonic acid metabolism implicating both the lipoxygenase and cyclooxygenase pathways. This results in imbalances of eicosanoid, leukotri...

Good's Syndrome, CVID, and Selective Antibody Deficiency in Patients with Chronic Rhinosinusitis.

Good's syndrome and common variable immune deficiency (CVID) are associated with chronic rhinosinusitis. Good's syndrome is characterized by hypogammaglobulinemia, B-cell depletion, variable defects i...

Influence of dietary pattern, physical activity, and I148M PNPLA3 on steatosis severity in at-risk adolescents.

Evidence relating dietary patterns to obesity and related disorders such as non-alcoholic fatty liver disease (NAFLD) is limited in pediatric age. Aim of this study was to analyze the association betw...

Platelet function testing in contemporary clinical and interventional practice.

Dual antiplatelet therapy with a combination of aspirin and an inhibitor of the ADP P2Y12 receptor is the recommended treatment for patients with acute coronary syndrome or who are undergoing percutan...

Management of hyponatremia in clinical hepatology practice.

The burden of liver disease continues to increase in the United States, with the epidemics of hepatitis C, alcoholic liver disease, and the coming wave of nonalcoholic fatty liver disease patients all...

Anti-epileptic drugs and hormonal treatments.

Epilepsy and the medications used in its treatment are known to affect the menstrual cycle, aspects of contraception, and bone health in women. Adolescence is an important time to review the diagnosis...

Development of Evidenced-Based Guidelines for PCOS and Implications for Community Health.

Despite the prevalence and health implications of polycystic ovary syndrome (PCOS), key evidence practice gaps exist including delayed diagnosis, inconsistent management, inadequate support for lifest...

Menopausal implications of polycystic ovarian syndrome.

Polycystic ovary syndrome (PCOS) is a common endocrinopathy affecting up to 8 to 10% of reproductive-aged women. Although the medical and metabolic consequences of PCOS are well-described in young rep...

Treatment of polycystic ovary syndrome in adolescence.

Adolescence is a time of rapidly changing reproductive hormones and menstrual patterns making diagnosis of polycystic ovary syndrome (PCOS) challenging in this population. Nonetheless, there is signif...

Childhood Obesity and Its Impact on the Development of Adolescent PCOS.

Obesity exacerbates the reproductive and metabolic manifestations of polycystic ovary syndrome (PCOS). The symptoms of PCOS often begin in adolescence, and the rising prevalence of peripubertal obesit...

News Articles [1248 Associated News Articles listed on BioPortfolio]

Brinks Charity Tourney a Big Win

Golf Tournament in Texas Supports The Research Down Syndrome Foundation Dallas, TX (PRWEB) April 18, 2014 Brink’s North America President Mel Parker was all smiles when a teammate sunk a 52 foot pu...

Progressive Neurodegenerative Disorder Linked to R-Loop Formation, UC Davis Researchers Find

Researchers at UC Davis have identified a new feature of the genetic mutation responsible for the progressive neurodegenerative disorder fragile X-associated tremor/ataxia syndrome (FXTAS) — the for...

Identification of KMT2D and KDM6A mutations by exome sequencing in Korean patients with Kabuki syndrome

Progressive neurodegenerative disorder linked to R-loop formation

Researchers at UC Davis have identified a new feature of the genetic mutation responsible for the progressive neurodegenerative disorder, fragile X-associated tremor/ataxia syndrome (FXTAS)—the form...

Teacher with chronic fatigue syndrome asks to be struck off | Edinburgh Evening News | 15 April 2014

Teacher worked at Dirleton Primary School in East Lothian

'Brain training' overcomes tics in Tourette syndrome, study finds

Children with Tourette Syndrome (TS) may unconsciously train their brain to more effectively control their tics. Teenagers diagnosed with Tourette Syndrome (TS) were slower than their typically develo...

Children with Tourette syndrome may unconsciously train brain to effectively control tics

Children with Tourette Syndrome (TS) may unconsciously train their brain to more effectively control their tics.

New syndrome osteosarcopenic obesity links deterioration of bone density and muscle mass with obesity

Florida State University researchers have identified a new syndrome called "osteosarcopenic obesity" that links the deterioration of bone density and muscle mass with obesity.

Genetics: Up and down in Down's syndrome

A comparison of identical human twins, only one of whom has Down's syndrome, reveals a genome-wide flattening of gene-expression levels in the affected individual. See Article p.345

Domains of genome-wide gene expression dysregulation in Down’s syndrome

Trisomy 21 is the most frequent genetic cause of cognitive impairment. To assess the perturbations of gene expression in trisomy 21, and to eliminate the noise of genomic variability, we studied the t...

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Companies [43 Associated Companies listed on BioPortfolio]

Akebia Therapeutics, Inc.

Akebia Therapeutics is a discovery and development company focused on anemia and vascular disorders. Akebia’s lead program, AKB-6548, an orally bioavailable HIF-prolyl hydrox...

XenoPort

We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

NPS Pharmaceuticals

NPS Pharmaceuticals is engaged in the discovery, development and commercialization of therapeutic small molecules and recombinant proteins to treat bone and mineral, gastrointestinal and central nervo...

My Possibilities

My Possibilities is a Plano, Texas-based non-profit, charity - 501(c)(3), for adults with disabilities (Autism, Down Syndrome, Aspergers, Prader-Willi, Head Injuries, etc.). St...

Sea-licious™

Karlene Karst, a Registered Dietician, is a leading health specialist in both nutrition and natural medicine. She is the co-author of the national best seller “Healthy...

Novaliq GmbH

"Novaliq GmbH is a medical technology / biopharmaceutical company with the aim to develop and market life-saving drug delivery systems for the treatment of severe lung diseases, such as for example ac...

Synergy Pharmaceuticals Inc.

Synergy Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development of new drugs to treat patients with gastrointestinal (GI) diseases and disorders. Synergyâ...

Avaxia Biologics, Inc.

Avaxia is a leader in the growing field of gut-targeted therapeutics — orally administered, minimally absorbed drugs that are designed to act locally in the gastrointestinal...

Sturge-Weber Foundation

Since its founding in 1987, the Sturge-Weber Foundation (SWF) has provided information, education and friendly support to adults and families of children with Sturge-Weber syndrom...

NeuroMetrix, Inc.

NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...

Clinical Trials [1806 Associated Clinical Trials listed on BioPortfolio]

Safety and Pharmacokinetics of Ifetroban in Hepatorenal Syndrome Patients

Cumberland Pharmaceuticals Inc. (CPI) is developing ifetroban for treatment of hepatorenal syndrome (HRS) and proposes to conduct a study in hospitalized adult patients with HRS to assess...

Guanfacine in Children With Tic Disorders

The goal of this pilot study is to obtain preliminary information on the tolerability and efficacy of extended release guanfacine (trade name Intuniv) in children with Tourette Disorder (T...

MAESTRO-OL: Macitentan in Eisenmenger Syndrome To Restore Exercise Capacity (Open-Label)

Long-term study to evaluate if macitentan is safe, tolerable and efficient enough to be used for treatment of Eisenmenger syndrome.

Survey of Patients With Idiopathic Orbital Inflammation Syndrome

The purpose of this study is to characterise the clinical features, histopathology and the treatment outcomes of patients with idiopathic orbital inflammation syndrome.

Randomized Study of ON 01910.Na in Refractory Myelodysplastic Syndrome Patients With Excess Blasts

The primary objective of this study is to compare overall survival (OS) in patients receiving ON 01910.Na + best supportive care (BSC) to OS of patients receiving BSC in a population of pa...

Observational Study to Investigate the Effectiveness of Eprosartan on Pulse Pressure (Teveten_MS)

The study is to identify the effectiveness of Eprosartan on pulse pressure in hypertensive patients with metabolic syndrome -Definition of pulse pressure (PP): Difference between systolic...

Efficacy of Mesalamine in Diarrhea-predominant Irritable Bowel Syndrome (dIBS)

The purpose of this study is to find whether treating patients with diarrhea predominant Irritable Bowel Syndrome (IBS) with an anti-inflammatory drug called Mesalamine will help improve t...

Efficacy of Minoxidil in Children With Williams-Beuren Syndrome

The Williams-Beuren syndrome (WBS) is a sporadic congenital disorder characterized by a multisystem developmental impairment. This syndrome is caused by a microdeletion in chromosome 7q11....

Sleep Disordered Breathing and Impaired Glucose Homeostasis in Obese Children

SDB has been identified as an important risk factor for insulin resistance and the metabolic syndrome. In a recent study in patients with SDB and T2DM it was shown that CPAP therapy can l...

Pre-Transplant 5-Azacitidine In Patients With High-Risk Myelodysplastic Syndrome Who Are Candidates For Allogeneic Hematopoietic Cell Transplant

The purpose of this study is to find out if treating people who have high-risk myelodysplastic syndrome (MDS) with Vidaza (also called 5-azacitidine) prior to their allogeneic hematopoieti...

Medical and Biotech [MESH] Definitions

An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.

A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.

A selective adrenergic alpha-1 antagonist used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention.

A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.

A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.

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