Revascularization Modalities and Indications - Biotech, Pharma and Life Science Channel
PubMed Articles
Breast cancer is the most common cancer in women worldwide. The disease remains a public health concern as recent evidence indicates that the breast cancer burden has increased mainly in developing an...
Cervical cancer is one of the leading causes of death among women with gynecological malignancies. In early stages of the disease (IB-IIA), surgical treatment alone is usually the treatment of choice....
Nano-Sized CT Contrast Agents.
Computed tomography (CT) is one of the most widely used clinical imaging modalities. In order to increase the sensitivity of CT, small iodinated compounds are used as injectable contrast agents. Howev...
The accurate detection and dosimetry of neutrons in mixed and pulsed radiation fields is a demanding instrumental issue with great interest both for the industrial and medical communities. In recent s...
In girls and young women, irradiation of the ovaries can reduce the number of viable ovarian primordial follicles, which may lead to premature ovarian failure (POF) and subsequently to sterility. One...
Optimal control oriented to therapy for a free-boundary tumor growth model.
This paper is devoted to present and solve some optimal control problems, oriented to therapy, for a particular model of tumor growth. In the considered systems, the state is given by one or several f...
Endobronchial Biopsy: A Guide for Asthma Therapy Selection in the Era of Bronchial Thermoplasty.
Objective. Bronchial thermoplasty (BT) reduces airway smooth muscle in patients with severe asthma. We developed a novel standardized histologic grading system assessing inflammation and structural re...
Recent advances in optogenetics and pharmacogenetics.
Optogenetics with microbial opsin genes, and pharmacogenetics with designer receptors, represent potent and versatile experimental modalities that can be integrated with each other as well as with a r...
Indications for and outcomes of valve replacement for asymptomatic aortic valve stenosis.
The efficacy of dynamic slow motion video endoscopy as a test of eustachian tube function.
Objective: To assess the efficacy of dynamic slow motion video endoscopy as a test of eustachian tube function based on its correlation with the eustachian tube swallow test. Method: The eustachian tu...
News Articles
Three Analyses Presented at EuroPCR Demonstrate Device's Durability in Addressing Common Clinical Challenge PARIS -- May 22, 2013 -- Addressing one of the most common clinical challenges in th...
A Trio Of Strategic VCs Helps To Back Effector Therapeutics With $45 Million
Using technology spun out of UCSF, a new company hopes to develop oncology drugs that target effector mechanisms of protein synthesis, thereby affecting multiple oncogenes simultaneously. The San Dieg...
Pfizer's leading ADC in Phase III study failure
Pfizer's Phase III program for its leading antibody-drug conjugate drug inotuzumab ozogamicin has got off to a disappointing start after a Phase III study in one of its indications was stopped due to...
Elan big biotech deals Speranza Therapeutics for ELND005 license
Elan has entered biotech deals and decides to divest ELND005 to, Speranza Therapeutics, focused on progressing the development of ELND005 (Scyllo-inositol). Leading to the biotech deals, current indic...
Ignyta acquires Actagene Oncology and entry into cancer personalized medicine
Privately-held US biotechnology company, Ignyta, which engages in catalyzing personalized medicine in autoimmune diseases, says it has acquired Actagene Oncology, effective May 20. Actagene was a San...
Stemedica Cell Technologies, Inc., a leader in adult allogeneic stem cell manufacturing, research and development, announced today that Robert L. Wilensky, MD, Professor of Medicine and Director of In...
Karyopharm raises $48.2 million in series B
Cancer company Karyopharm Therapeutics Inc. (Natick, Mass.) raised $48.2 million in a series B round led by an undisclosed private investor. New investor Delphi Ventures and additional undisclosed inv...
Effector raises $45M in tranched series A
Effector Therapeutics Inc. (San Diego, Calif.) raised $45 million in a tranched series A round co-led by U.S. Venture Partners; Abingworth; Novartis Venture Funds; and SR One. Astellas Venture Managem...
STENTYS Enrolls First Heart Attack Patient in Pivotal U.S. Clinical Trial
STENTYS (FR0010949404 – STNT), a medical technology company commercializing in Europe the world's first and only Self-Apposing® Stent to treat acute myocardial infarction (AMI)...
Catalyst Pharmaceutical's CPP-115 May Be Big Pipeline In Just One Little Pill
ByMichael Anderson:I've been searching and researching for new drugs that have a high potential to become blockbusters and big stock winners and I came across one that looks particularly interesting....
Companies
Izun Pharmaceuticals Corporation
Izun Pharmaceuticals is a US based pharmaceutical company with a wholly owned R&D center in Israel. Izunâs technology platform allows it to develop botanical drugs by optimiz...
Kite Pharma, Inc. is a privately held development stage biotechnology company engaged in the design and development of cutting-edge immunotherapeutic products to treat different c...
Toshiba America Medical Systems Inc.
With headquarters in Tustin, Calif., Toshiba America Medical Systems markets, sells, distributes and services diagnostic imaging systems, and coordinates clinical diagnostic imagi...
Phytoceuticals is a life science company that develops intellectual property from natural product extracts, defines scientifically sound development protocols, manages product dev...
Mimetogen Pharmaceuticals Inc.
Mimetogen Pharmaceuticals, Inc. began operations in 2006, developing the use of peptidomimetics as novel approaches to treat diseases with high unmet medical needs. The underlying...
Ivivi Health Sciences is an emerging leader in the field of inductive electrotherapy. Its lead product, the Ivivi Torino II, has a demonstrated mechanism of action and proven clin...
SpringLeaf Therapeutics is creating innovative therapeutic modalities to address serious disease and elevate the quality of care for patients. SpringLeafâs technology is b...
Enterologics, Inc. (OTCBB: ELGO.OB) is a biotechnology company that is developing probiotics as biologic drugs for specific gastrointestinal disease indications. Probiotics are li...
Radimetrics provides radiation dose monitoring and management software to hospitals and imaging centers. Radimetricsâ flagship product, eXposure⢠is a single-system solu...
Amp Orthopedics develops innovative, non-invasive products for the treatment of post-operative pain and edema in orthopedic indications. These products use an FDA approved and CE...
Clinical Trials
Evaluation of Myocardial Viability by Means of Low-Dose Dobutamine Gated SPECT (the DOGS Study)
Viability assessment remains a clinical challenge in patient with coronary artery disease and left ventricular dysfunction. Several imaging modalities are available for evaluating myocardi...
Follow-up Modalities of Low Grade Precancerous Bronchial Lesions
The goal of this multicentric French randomized trial is to determine the best auto fluorescence bronchial endoscopic follow-up strategy in high risk patients bearing low grade bronchial...
Safety and Acceptability of Carraguard™ Among HIV-Negative Couples in Thailand
The primary aims of the study were to assess the safety and acceptability of Carraguard applied vaginally prior to sexual intercourse for six months in both women and men; and to examine s...
Development of an Evaluation Method of Elderly Condition in Patient Receiving Chemotherapy Treatment
Number of elderly people over 70 is increasing in France. In 2002, in the south-west, 273,741 of them were over 75 years, i.e. 9.2% of Aquitaine population. Incidence of cancer in this old...
SMART Trial Longitudinal Follow-Up:Off-Pump Versus On-Pump Coronary Artery Bypass Surgery
The purpose of this study is to determine completeness of revascularization, graft patency, clinical outcomes, health-related quality of life and costs in 200 initial trial participants at...
Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization
The PATCAR study has been designed to test the hypothesis that the strategy of pre-hospital use of a "clot busting" (thrombolytic) drug followed with emergent heart catheterization includi...
The Study of Human Atherosclerosis by Polarization-Sensitive Optical Coherence Tomography
Atherosclerosis is unquestionably the leading cause of morbidity and mortality in developed countries, and the world-wide importance of acute vascular syndromes is increasing. Rupture of a...
Mobilization Techniques in Patients With Frozen Shoulder: a Randomized Multiple-Treatment Trial
Background: Frozen shoulder syndrome (FSS) or adhesive capsulitits, a condition of uncertain etiology characterized by a progressive loss of both active and passive shoulder motion, is one...
Sublingual Immunotherapy With House Dust Mite Extract in Asthmatic Children
Asthma, the airway inflammatory disorder, is an important chronic disease in children. About 10~15% children are bothered with this. Allergens, such as house-dust mites (HDM), animal dande...
EArly Discharge After Transradial Stenting of CoronarY Arteries: The EASY Study
HYPOTHESES - Discharge on the same day after uncomplicated trans-radial coronary artery stenting is safe and effective. - Hospitalized patients can be safely returned to...
Videos
Medicine Today - Ep. 8 - Cardiogenic Shock and Mechanical Complications
This Cardiogenic Shock and Mechanical Complications webcast, from the 23rd Annual Intensive Review of Internal Medicine Symposium, discusses the pathogenesis...
Medical and Biotech [MESH] Definitions
Cone-beam Computed Tomography
Computed tomography modalities which use a cone or pyramid-shaped beam of radiation.
Osteochondrosis
Any of a group of bone disorders involving one or more ossification centers (EPIPHYSES). It is characterized by degeneration or NECROSIS followed by revascularization and reossification. Osteochondrosis often occurs in children causing varying degrees of discomfort or pain. There are many eponymic types for specific affected areas, such as tarsal navicular (Kohler disease) and tibial tuberosity (Osgood-Schlatter disease).
Molecular Imaging
The use of molecularly targeted imaging probes to localize and/or monitor biochemical and cellular processes via various imaging modalities that include RADIONUCLIDE IMAGING; ULTRASONOGRAPHY; MAGNETIC RESONANCE IMAGING; fluorescence imaging; and MICROSCOPY.
Recreation Therapy
The enhancement of physical, cognitive, emotional and social skills so an individual may participate in chosen activities. Recreational modalities are used in designed intervention strategies, incorporating individual's interests to make the therapy process meaningful and relevant.
Transmyocardial Laser Revascularization
A procedure to increase the flow of blood to the MYOCARDIUM by creating transmural channels in the heart wall via the application of laser pulses to epicardial or endocardial surfaces.
