Serum urate level - Biotech, Pharma and Life Science Channel
PubMed Articles
Objective-To compare treatment protocols for chronic enteropathy and concurrent protein-losing enteropathy that used prednisolone in conjunction with either azathioprine or chlorambucil in dogs. Desig...
Soluble CD27-Pool in Humans May Contribute to T Cell Activation and Tumor Immunity.
The interaction between CD27 and its ligand, CD70, has been implicated in regulating cellular immune responses to cancer. In this article, we report on the role of soluble CD27 (sCD27) in T cell activ...
NSE, neuron-specific enolase, is an important biomarker for several pathological conditions including small cell lung cancer (SCLC). The current paper presents an LC-MS/MS-based approach for quantific...
Here, we describe the development and application of a liquid chromatography-tandem mass spectrometry method with positive electrospray ionisation and scheduled multiple reaction monitoring algorithm...
A LC-ESI-MS/MS method for the determination of crenolanib (CP-868,596) in human serum was developed and validated employing d4-CP-868,596 as an internal standard (ISTD). In addition to human serum, th...
Heavy neurofilaments (NFH) released from neurons during axonal injury induce a humoral immune response. We measured CSF and serum levels of NFH proteins and anti-NFH IgG antibodies in 19 patients with...
Therapeutic drug monitoring (TDM) may be very useful in the clinical management of antiepileptic drug therapy for multiple reasons, such as individual variability, metabolism, genetic factors or drug-...
Prenatal passive transfer of maternal immunity in Asian elephants (Elephas maximus).
Asian (Elephas maximus) and African (Loxodonta africana) elephants exhibit characteristics of endotheliochorial placentation, which is common in carnivore species and is associated with modest materna...
At therapeutic doses, acetaminophen (APAP) is a safe and effective analgesic. However, overdose of APAP is the principal cause of acute liver failure in the West. Binding of the reactive metabolite of...
Immune activation and inflammation represent critical factors in the pathogenesis of Alzheimer's disease (AD) and are associated with increased blood concentrations of markers like neopterin and the k...
News Articles
Senesco Announces Results of Cohort 2 of its SNS01-T Phase 1b/2a Trial
Senesco Technologies, Inc. (“Senesco” or the “Company”) (OTC QB: SNTI) reported results of cohort 2 in its Phase 1b/2a clinical study of SNS01-T. In cohort...
Aftermath Inc. Biohazard Removal Services Now Using ATP Testing Technology
Detectors will be used to measure biological cleanliness at crime scenes, trauma clean-up. Aurora, IL (PRWEB) June 19, 2013 Aftermath Inc., the country’s leading biohazard remediation company, anno...
Unexplained deaths spark FDA probe of Lilly's Zyprexa Relprevv
High doses of olanzapine can cause delirium, cardiopulmonary arrest, cardiac arrhythmias and reduced level of consciousness ranging from sedation to coma, the agency said in a MedWatch alert to health...
Chairman Level CEO Level President Level Executive Level Board Level Executive Vice President Level Vice President, Corporate Communications Level Executive Suite Sponsorship Opportuniti...
Recent executive-level company changes and promotions in the biopharma, medical device, and diagnostics industries.
Manches' Patent Expertise Recognised at an International Level (News)
04 June 2013: Oxford, UK - Manches LLP Thames Valley is delighted to announce that intellectual property partner, Chris Shelley, has been recognised as one of the World's Leading Patent Practitioners...
Changes in lipid levels with inflammation and therapy in RA: a maturing paradigm
Despite having increased cardiovascular risk, patients with rheumatoid arthritis (RA) often have low serum cholesterol levels. In this Review, the authors discuss this putative 'lipid paradox', highli...
Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism
In this Review, the author discusses new insights into the pathogenesis of chronic kidney disease and describes a novel mechanism of ageing, both in the context of the fibroblast growth factor (FGF)...
Association Between Eating Behaviors In Preschoolers And Later Cardiovascular Risk
Eating behaviors of preschoolers may be associated with risk of cardiovascular disease in later life, suggests a study published in CMAJ (Canadian Medical Association Journal). A study of 1076 prescho...
TruAir’s broad-spectrum protection — NIOSH approved N95, N99, and P100 level protection — have made the entire TruAir line extremely popular in myriad industries. TruAir and TruAir Plus, NIOSH...
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Companies
Catalina Health® is committed to helping our partners deliver unprecedented performance and healthier outcomes for their health consumers. Our proprietary platforms enable the...
Overlake Hospital Medical Center is a nonprofit, non-tax-supported regional medical center with a network of medical clinics throughout the Eastside. The hospital is licensed for...
DecisionSim⢠is a web-based virtual patient platform enabling healthcare providers, academic institutions and professional societies to cost-effectively develop, improve and...
Biodesix is a personalized medicine company focused on the development of diagnostic products that inform treatment decisions and improve patient care. In 2009, Biodesix launched VeriStrat®, a serum...
IRI Consulting provides strategic insights and actionable recommendations to leverage growth with support from IRIâs proprietary, granular data, analytics and technology asse...
Circadian Technologies Limited
Circadian Technologies Limited is an emerging leader in the field of angiogenesis-based treatments for cancer. Focusing on a class of drug targets called Vascular Endothelial Growth Factors (VEGFs),...
Xenex Healthcare Services and Louisiana Continuing Care Hospital
Established in 1995, LCCH is certified by Medicare to operate up to 56 beds. Currently, the hospital is licensed for 33 high acuity beds serving medically complex patients who typ...
ReNu Medical, founded in 2000, provides immediate solutions to rising healthcare costs. ReNu is a FDA-registered, High Level Disinfection (HLD) reprocessor of non-critical and sem...
Rothman Healthcare Corporation
Since 2004, Rothman Healthcare Corporation has been developing the Patient Condition Tracker to bridge gaps in continuity of care. Rothman's software application uses electronic h...
CytomX Therapeutics is an early stage biotechnology company developing Probodiesâ¢, or proteolytically-activated antibodies. Probodies combine the well-established power and s...
Clinical Trials
Intravitreal LFG316 in Patients With Age-related Macular Degeneration (AMD)
This study is designed to test the efficacy of twelve successive monthly doses of intravitreal (IVT) LFG316 on the growth of geographic atrophy (GA) lesions. The study will also provide in...
Brentuximab Vedotin (SGN-35) as Salvage Treatment for CD30-positive Germ Cell Tumors
Complete responses with third-line or later salvage chemotherapy (CT) for germ cell tumors (GCT) range 0% to 10% and are usually short-lived and nearly all patients (pts) progressing after...
Low-level Laser Therapy on Temporomandibular Disorder
The purpose of this study is to assess the effect of low-level laser on pain, occlusal contacts, mandibular movements and electromyography activity in the masseter and temporal muscles in...
Our long-term working hypothesis is that if 3-D radiation is combined with the effect of capecitabine one hopes to see improved and durable tumor response and survival with acceptable toxi...
The overall objective of the project is to contribute to an increased knowledge about the effect of praziquantel on schistosomiasis related morbidity and re-infection level among communiti...
Dosage Effects of Folic Acid on Blood Folates of Honduran Women
CDC staff at the National Center on Birth Defects and Developmental Disabilities have been working closely with a Honduras-based organization, Project Healthy Children (PNS) and the Minist...
The Effects of Anabolic Steroids and Protease Inhibitors on People Living With HIV/AIDS
The main aim of the study is to investigate the combined effects of using anabolic steroids and protease inhibitors on fat metabolism and body composition of People Living with HIV/AIDS....
The trial is planned as a multicentric, randomized, prospective, open study in accordance with a 1/1 plan, on parallel groups and 2 arms of treatment. A total of 200 patients with chronic...
Serum HBV DNA is a referent but insufficient marker of therapeutic follow-up in chronic hepatitis B treatment. Intra hepatic cccDNA disappearance reflects HBV eradication in the liver....
Study of the Pharmacokinetic Action of Amantadine and Ribavirin in Chronic Hepatitis C. CINAM
Peg interferon and ribavirin currently represent the standard approved association for treating patients infected with hepatitis C virus (HCV) . The adjunction of amantadine is expected to...
Videos
Careful Use of Currently Available Gout Drugs Can Put an End to Acute Attacks
General internists often continue to treat gout the way they were taught to as medical students, and the result of that approach has been that patients conti...
Medical and Biotech [MESH] Definitions
Hyperuricemia
Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.
Transferrin-binding Proteins
A class of carrier proteins that bind to TRANSFERRIN. Many strains of pathogenic bacteria utilize transferrin-binding proteins to acquire their supply of iron from serum.
Bacterial Transferrin Receptor Complex
A complex of proteins that forms a receptor for TRANSFERRIN in BACTERIA. Many pathogenic bacteria utilize the transferrin-binding complex to acquire their supply of iron from serum.
Hypoalbuminemia
A condition in which albumin level in blood (SERUM ALBUMIN) is below the normal range. Hypoalbuminemia may be due to decreased hepatic albumin synthesis, increased albumin catabolism, altered albumin distribution, or albumin loss through the urine (ALBUMINURIA).
Hyperamylasemia
A condition with abnormally elevated level of AMYLASES in the serum. Hyperamylasemia due to PANCREATITIS or other causes may be differentiated by identifying the amylase isoenzymes.
