Sleep Apnea - Biotech, Pharma and Life Science Channel
Sleep apnea (AP-ne-ah) is a common disorder in which you have one or more pauses in breathing or shallow breaths while you sleep. Breathing pauses can last from a few seconds to minutes. They often occur 5 to 30 times or more an hour. Typically, normal breathing then starts again, sometimes with a loud snort or choking sound. Sleep apnea usually is a chronic (ongoing) condition that disrupts your sleep. You often move out of deep sleep and into light sleep when your breathing pauses or becomes shallow. This results in poor sleep quality that makes you tired during the day. Sleep apnea is one of the leading causes of excessive daytime sleepiness.
Sleep apnea often goes undiagnosed. Doctors usually can't detect the condition during routine office visits. Also, there are no blood tests for the condition. Most people who have sleep apnea don't know they have it because it only occurs during sleep. A family member and/or bed partner may first notice the signs of sleep apnea.
The most common type of sleep apnea is obstructive sleep apnea. This most often means that the airway has collapsed or is blocked during sleep. The blockage may cause shallow breathing or breathing pauses. Obstructive sleep apnea is more common in people who are overweight, but it can affect anyone. For example, small children may have enlarged tonsil tissues in their throats, which can lead to obstructive sleep apnea.
Central sleep apnea is a less common type of sleep apnea. This disorder happens if the area of your brain that controls your breathing doesn't send the correct signals to your breathing muscles. As a result, you'll make no effort to breathe for brief periods. Central sleep apnea can occur in anyone. However, it's more common in people who have certain medical conditions or use certain medicines. Central sleep apnea often occurs with obstructive sleep apnea, but it can occur alone. Snoring doesn't typically happen with central sleep apnea.
Untreated sleep apnea can increase the risk of cardiovascular disease. Sleep apnea is a chronic condition that requires long-term management. Lifestyle changes, mouthpieces, surgery, and/or breathing devices can successfully treat sleep apnea in many people.
Source; http://www.nhlbi.nih.gov/
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PubMed Articles
Genetic analysis of candidate SNPs for metabolic syndrome in obstructive sleep apnea (OSA).
Obstructive sleep apnea (OSA) is a common disorder characterized by the reduction or complete cessation in airflow resulting from an obstruction of the upper airway. Several studies have observed an i...
Previous echocardiographic studies using tissue Doppler imaging (TDI) and speckle tracking imaging (STI) have demonstrated that obstructive sleep apnea syndrome (OSAS) patients may develop subclinical...
Physical predictors for moderate to severe obstructive sleep apnea in snoring patients.
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Prevalence and risk factors for insomnia among Portuguese adolescents.
Epidemiologic studies have shown that insomnia is the most prevalent sleep disorder at all ages, associated with sociodemographic and environmental factors and lifestyle. The aim of this study was to...
Treatment of Restless Legs Syndrome.
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Cholinergic basal forebrain structures are implicated in cortical arousal and regulation of the sleep-wake cycle. Cholinergic neurones are innervated by noradrenergic terminals, noradrenaline excites...
Comparison between the rhythmic jaw contractions occurring during sleep and while chewing.
The masticatory central pattern generator (CPG) may be implicated in the pathophysiology of sleep bruxism (SB). The aim of this study was to compare rhythmic masticatory muscle activity (RMMA) occurri...
Prevalence of sleep bruxism in children: a systematic review of the literature.
The aim of the present investigation was to perform a systematic review of the literature dealing with the issue of sleep bruxism prevalence in children at the general population level. Quality assess...
Clinical characteristics of patients with resistant hypertension: the RESIST-POL study.
Recent studies indicate that resistant hypertension (RHTN) is present in about 12% of the treated hypertensive population. However, patients with true RHTN (confirmed out of the office) have not been...
BACKGROUND: Sleep-disordered breathing (SDB), also known as obstructive sleep apnea (OSA), has been increasingly recognized as a possible risk factor for adverse perioperative outcomes in non-bariatri...
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Companies
Physician Therapeutics is a division of Targeted Medical Pharma, Inc., a specialty pharmaceutical company that develops and sells prescription medical foods to physi...
AZ-TMJ is a clinic focused on the treatment of TMJ, Severe Headaches and Sleep Apnea, all of which can be symptoms of an issue with the Temporomandibular Joint, which is where the...
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An Open-Label Study of Atomoxetine in Children With Attention-Deficit/Hyperactivity Disorder
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Videos
Sleep Apnea Treatment - How To Cure Sleep Apnea
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Medical and Biotech [MESH] Definitions
Nocturia
Frequent URINATION at night that interrupts sleep. It is often associated with outflow obstruction, DIABETES MELLITUS, or bladder inflammation (CYSTITIS).
Nocturnal Enuresis
Involuntary discharge of URINE during sleep at night after expected age of completed development of urinary control.
Sinus Arrest, Cardiac
The omission of atrial activation that is caused by transient cessation of impulse generation at the SINOATRIAL NODE. It is characterized by a prolonged pause without P wave in an ELECTROCARDIOGRAM. Sinus arrest has been associated with sleep apnea (REM SLEEP-RELATED SINUS ARREST).
Orthokeratologic Procedures
An alternative to REFRACTIVE SURGICAL PROCEDURES. A therapeutic procedure for correcting REFRACTIVE ERRORS. It involves wearing CONTACT LENSES designed to force corrective changes to the curvature of the CORNEA that remain after the lenses are removed. The effect is temporary but is maintained by wearing the therapeutic lenses daily, usually during sleep.
National Heart, Lung, And Blood Institute (u.s.)
Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports research program related to diseases of the heart, blood vessels, lung, and blood; blood resources; and sleep disorders. From 1948 until October 10, 1969, it was known as the National Heart Institute. From June 25, 1976, it was the National Heart and Lung Institute. Since October 1997, the NHLBI has also had administrative responsibility for the NIH Woman's Health Initiative.
