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GenVec Company Profile

22:09 EDT 25th September 2017 | BioPortfolio

GenVec, Inc. (NASDAQ: GNVC) is a biopharmaceutical company developing novel gene-based therapeutic drugs and vaccines. Each of our gene-based therapeutic product candidates use a common patent-protected technology platform to deliver genes that produce medically beneficial proteins directly at the site of disease. TNFerade™ represents a novel approach to treating cancer in combination with radiation and/or chemotherapy by introducing tumor necrosis factor-alpha (TNF-alpha), a potent anti-cancer protein, directly into tumors. Pancreatic cancer is the lead indication for TNFerade™. We are conducting a 330-patient randomized, controlled Phase II/III clinical trial designed to assess the safety and clinical benefit of using TNFerade™ in combination with standard of care treatment in patients with locally advanced pancreatic cancer. Phase II trials in rectal cancer and melanoma are also ongoing. AdPEDF is being developed for patients with wet age-related macular degeneration (AMD) to determine whether pigment epithelium-derived factor (PEDF) prevents vision loss in this leading cause of blindness in people over the age of 50. We have completed a Phase I clinical trial of PEDF in patients with severe AMD. Data from this trial demonstrated that PEDF was generally well tolerated with no dose limiting toxicities. Expanded clinical testing of PEDF in AMD patients with less severe disease is ongoing. TherAtoh Atonal Therapy is a product concept to restore hearing or balance function through the regeneration of critical cells of the inner ear. Hearing and Balance require specialized cells of the inner ear called sensory hair cells. During embryonic development a gene termed atonal (ATOH) induces the generation of these cells. GenVec has shown preclinically that the production of the ATOH protein results in the formation of new inner ear sensory hair cells, and the restoration of hearing and balance function. TherAtoh is an adenovector product delivering the human atonal gene (Hath1) to trigger the production of therapeutic proteins by cells in the inner ear. We also are using GenVec's proprietary adenovector technology to develop vaccines for infectious diseases. Worldwide HIV vaccine in collaboration with the National Institute of Allergy and Infectious Diseases (NIAID) Malaria vaccine in collaboration with U.S. Navy and PATH's Malaria Vaccine Initiative Foot and Mouth Disease antiviral and vaccine program in collaboration with the United States Department of Agriculture/Agricultural Research Services (USDA-ARS) Seasonal and pandemic influenza vaccines in collaboration with the National Institute of Allergy and Infectious Diseases (NIAID) GenVec, Inc. is based in Gaithersburg, Maryland. GenVec, Inc. is based in Gaithersburg, Maryland.

Location

65 West Watkins Mill Road
Gaithersburg
Maryland
20878
United States of America

Contact

Phone: (240) 632-0740 or (877) 943-6832
Fax: (240) 632-0735
Email: resume@genvec.com


News Articles [12 Associated News Articles listed on BioPortfolio]

GenVec to Present at the 14th Annual BIO CEO & Investor Conference

GAITHERSBURG, Md., Feb. 7, 2012 /PRNewswire/ -- GenVec, Inc. (Nasdaq: GNVC), a biopharmaceutical company using differentiated, proprietary technologies to create superior therapeutics and vaccine...

Intrexon Integrates Leading Adenoviral Gene Delivery Technology with Completion of GenVec ...

Additionally Intrexon's RheoSwitch Therapeutic System ® platform combined with GenVec's AdV-based technology is projected to accelerate its ability to develop cutting-edge gene therapies that regu...

Intrexon acquires gene delivery company GenVec

Intrexon Corp. acquired GenVec Inc. (gene delivery) for an undisclosed price.

GenVec To Release Fourth Quarter And Year-end 2012 Financial Results And Conduct A Conference Call On March 22, 2013

GAITHERSBURG, Md., March 15, 2013 /PRNewswire/ -- GenVec, Inc. (Nasdaq: GNVC) will report financial results for the fourth quarter and year ended December 31, 2012 on Friday, March 22, 2013, befo...

GenVec, Inc. Mergers Acquisitions MA, Partnerships Alliances and Investment Report [Updated: 05052017] Prices from USD $350

GenVec, Inc. Mergers Acquisitions MA, Partnerships Alliances and Investment ReportSummaryMarketline's GenVec, Inc. Mergers Acquisitions MA, Partnerships Alliances and Investments report includes ...

GenVec, Inc. Mergers Acquisitions MA, Partnerships Alliances and Investment Report [Report Updated: 12062017] Prices from USD $350

GenVec, Inc. Mergers Acquisitions MA, Partnerships Alliances and Investment ReportSummaryMarketline's GenVec, Inc. Mergers Acquisitions MA, Partnerships Alliances and Investments report includes ...

Faruqi & Faruqi, LLP Announces Investigation of GenVec, Inc.

NEW YORK, Feb. 6, 2012 /PRNewswire/ -- Faruqi & Faruqi, LLP, a leading national securities law firm, is investigating potential securities fraud at GenVec, Inc. ("GenVec" or the "Company") (Nasdaq...

Intrexon Integrates Gene Delivery Technology with Completion of GenVec Acquisition

Intrexon Corporation, specializing in the engineering and industrialization of biology to improve the quality of life and health of the planet, has completed the acquisition of GenVec, Inc., a clinic...

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Companies [2 Associated Companies listed on BioPortfolio]

GenVec, Inc.

GenVec

GenVec, Inc. (NASDAQ: GNVC) is a biopharmaceutical company developing novel gene-based therapeutic drugs and vaccines. Each of our gene-based therapeutic product candidates use a common patent-protect...

More Information about "GenVec" on BioPortfolio

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