Angstrom Pharmaceuticals Incorporated Company Profile
Ångstrom Pharmaceuticals, Inc. was formed in 1996 to add a new dimension to drug discovery. It is committed to discovering drugs that block the docking of an extracellular regulatory protein (ligand) to its receptor found on the outside of a cell – when this event is responsible for initiating a disease state. Receptors can be identified that trigger several intractable diseases including cancer, the first focus of the Company's mission. Ångstrom targets a receptor for blockade only following a detailed analysis of that receptor’s role in the disease. The blocking drugs are designed such that they can easily reach their site of action and have minimal side effects.
Ã…ngstrom has integrated the most advanced structure-based drug design, combinatorial science and state-of-the-art biology to create molecules that potently block the ligand-receptor docking interaction. From the intellectual property viewpoint, structure-based design, boldly applied, is inevitably creative resulting in an unassailable patent portfolio.
Location
11772 Sorrento Valley Road #105
San Diego
CA
92121
United States of America
Contact
Phone: 619 350 1760
Fax: 619 350 1761
News Articles
SPring-8 Angstrom Compact free-electron Laser demonstrates shortest wavelength and high peak output
A detailed technical introduction to the SPring-8 Angstrom Compact free-electron Laser (SACLA) appeared online in Nature Photonics. The attention on the world's second XFEL facility comes in response...
A compact X-ray free-electron laser emitting in the sub-ångström region
Researchers report sub-ångström fundamental-wavelength lasing at the SPring-8 Angstrom Compact Free-Electron Laser in Japan. The output has a maximum power of more than 10 GW, a pulse duration of 1...
A toolkit and benchmark study for FRET-restrained high-precision structural modeling
A collection of simulation tools and workflow for single-molecule Förster resonance energy transfer (smFRET) allows highly quantitative structural modeling. This hybrid approach yields a model of rev...
SACLA draws acclaim for unique XFEL design
(RIKEN) A detailed technical introduction to the SPring-8 Angstrom Compact free-electron Laser (SACLA) appeared online in Nature Photonics.SACLA boasts the shortest wavelength in the world, an extreme...
Drugs and Medications
None
PubMed Articles
Chirality of the 1,4-phenylene-silica nanoribbons at the nano and angstrom levels.
We reported the preparation of chiral 1,4-phenylene-silicas, using a sol-gel transcription approach, by self-assembly using low-molecular-weight gelators as templates. The silicas exhibited chirality...
The structural basis of ZMPSTE24-dependent laminopathies.
Mutations in the nuclear membrane zinc metalloprotease ZMPSTE24 lead to diseases of lamin processing (laminopathies), such as the premature aging disease progeria and metabolic disorders. ZMPSTE24 pro...
Microfluidic stretchable RF electronics.
Stretchable electronics is a revolutionary technology that will potentially create a world of radically different electronic devices and systems that open up an entirely new spectrum of possibilities....
Imaging ultrafast dynamics of molecules with laser-induced electron diffraction.
We introduce a laser-induced electron diffraction method (LIED) for imaging ultrafast dynamics of small molecules with femtosecond mid-infrared lasers. When molecules are placed in an intense laser fi...
Isocyanide (formerly isonitrile) hydratase (EC 4.2.1.103) is an enzyme of the DJ-1 superfamily that hydrates isocyanides to yield the corresponding N-formamide. In order to understand the structural b...
Clinical Trials
None
Companies
We are an integrated and leading supplier of UV fluorescent chemicals and electronic detection systems. Since 1983, many prominent companies and financial institutions have used Angstrom's products fo...
Angstrom Pharmaceuticals Incorporated
Ã…ngstrom Pharmaceuticals, Inc. was formed in 1996 to add a new dimension to drug discovery. It is committed to discovering drugs that block the docking of an extracellular regulatory protein (ligand)...
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