Applied Molecular Company Profile

19:25 EDT 23rd September 2017 | BioPortfolio

Applied Molecular Evolution, Inc. (AME) is a leader in the application of directed molecular evolution to improve healthcare by optimizing and developing human biotherapeutics. AME uses its proprietary AMEsystem™ directed molecular evolution technology platform to optimize genes and therapeutic proteins for specific commercial purposes. AME optimizes the full range of proteins, including antibodies, cytokines, hormones and enzymes to develop improved versions of currently marketed, FDA-approved biotherapeutics as well as novel human biopharmaceuticals.

AME has collaborations with leading developers of biotherapeutics including Centocor, Lilly, Chiron, MedImmune, Bristol-Myers Squibb, Seattle Genetics, Cell Matrix and Biosynexus, whose biopharmaceutical projects may benefit from significant optimization of therapeutic and commercial parameters including:

Improved safety, efficacy and potency

Enhanced convenience

Decreased manufacturing costs

Broadened and lengthened patents


3520 Dunhill Street
San Diego
United States of America


Phone: (858) 597-4990
Fax: (858) 597-4950

News Articles [1298 Associated News Articles listed on BioPortfolio]

Applied BioMath, LLC to Present Poster on Quantitative Systems Pharmacology Modeling of ...

Applied BioMath's poster highlights how their quantitative systems pharmacology (QSP) approach provides biological insights into the impact of drug-to-antibody ratio and the resulting changes in mo...

Study examines cross-species interactions

In a first-of-its-kind study, NC State researchers applied a new approach to examine how members of two different species – a plant and a pathogen, for example, or a bacterium and a human – intera...

Giant molecular cages made for energy conversion and drug delivery

The porous, 'sponge'-type molecules have an enormous internal surface area. This allows their use as 'molecular flasks' or 'molecular containers' that change the reactivity and properties of encapsula...

The Optical Society announces plenary highlights at 2017 Imaging and Applied Optics Congress

(The Optical Society) The OSA Imaging and Applied Optics Congress will begin with a plenary program hosted by award-winning film and television cinematographer, John Schwartzman, and University of Cal...

AMP to recognize Andrew P. Feinberg, M.D., M.P.H. with 2017 Award for Excellence in Molecular Diagnostics

(Association for Molecular Pathology) The Association for Molecular Pathology (AMP), the premier global, non-profit organization serving molecular diagnostic professionals, today announced that Andrew...

Scientists make giant molecular cages for energy conversion and drug delivery

(Trinity College Dublin) The porous, 'sponge'-type molecules have an enormous internal surface area. This allows their use as 'molecular flasks' or 'molecular containers' that change the reactivity an...

Applied Biosystems 2720 Thermal Cycler 96 well

$79.99 (0 Bids)End Date: Monday May-29-2017 8:05:38 PDTBid now | Add to watch list Biotech365 : Applied Biosystems 2720 Thermal Cycler 96 well BioMarketplace You want to propose your products or ...

2017 World Molecular Diagnostics Market: Sales and Market Shares of Major Suppliers [Updated: 22032017] Prices from USD $4850

This unique report from VPGMarketResearch provides sales and market share estimates for major suppliers of molecular diagnostic products by country.The report also presents strategic assessments of ma...

Drugs and Medications [394 Associated Drugs and Medications listed on BioPortfolio]

Xolegel [Stiefel Laboratories Inc]


Sun savvy solar shield [APPLIED SKIN TECHNOLOGY LLC]


U40 [Kylemore Pharmaceuticals, LLC]

U40 Foam

Mometasone furoate ointment usp, 0.1% [E. FOUGERA and CO.]


Mometasone furoate [Physicians Total Care, Inc.]

PubMed Articles [2617 Associated PubMed Articles listed on BioPortfolio]

Acute Myeloid Leukemia (AML): Upregulation of BAALC/MN1/MLLT11/EVI1 Gene Cluster Relate With Poor Overall Survival and a Possible Linkage With Coexpression of MYC/BCL2 Proteins.

Molecular heterogeneity accounts for the variable and often poor prognosis in acute myeloid leukemia (AML). The current risk stratification strategy in clinical practice is limited to karyotyping and ...

Spectral clustering using Nyström approximation for the accurate identification of cancer molecular subtypes.

A major challenge in clinical cancer research is the identification of accurate molecular subtype. While unsupervised clustering methods have been applied for class discovery, this clustering method r...

Science to Practice: Multiparametric Molecular and Functional US Imaging Goes Three-dimensional.

Although microbubbles can boost the diagnostic value of ultrasonography (US), they are not routinely applied in clinical tumor diagnosis. This can be explained by the limited reproducibility of US exa...

Improved and Standardized Approaches to Selection of Control Materials From ISIMM: Announcing a Workshop at the Annual ASCP Meeting, September 6-7, 2017, Sponsored by the International Society for Immunohistochemistry and Molecular Morphology.

Bio-functions and molecular carbohydrate structure association study in forage with different source origins revealed using non-destructive vibrational molecular spectroscopy techniques.

The objectives of this study were to: 1) investigate forage carbohydrate molecular structure profiles; 2) bio-functions in terms of CHO rumen degradation characteristics and hourly effective degradati...

Clinical Trials [2100 Associated Clinical Trials listed on BioPortfolio]

Pregnancy Outcome of Women Using Low Molecular Weight Heparin Before Frozen-thawed Embryo Transfer

Embryo freezing is a technique used commonly to optimize the pregnancy rate in assisted reproduction techniques (ART). Hormone replacement therapy (HRT) regimen is applied to prepare endom...

Study of Sperm Molecular Factors Implicated in Male Fertility

Sperm analysis following World Health Organization guidelines is unable to explain the molecular causes of male infertility when basic sperm parameters are within a normal range and women ...

The Application of Ticagrelor Combined With Low Molecular Weight Heparin During PCI

The purpose of this study is to determine ticagrelor combining with low molecular weight heparin is effective and safe during PCI or not.

In Vivo EGFR Molecular Classification

The investigators developed 18F-MPG as a targeted molecular imaging agent for noninvasive and repeatable detecting EGFR-activating mutational status.

Clinical Value of Molecular Genetic Analyzes in Gynecological Malignomas

The aim of the planned research project is to find out the clinical significance of molecular genetic analyzes in gynecological malignomas. In particular, it will be investigated how the k...

Companies [1198 Associated Companies listed on BioPortfolio]

Applied BioCode, Inc.

Applied BioCode, Inc. is a privately held biotechnology company with headquarters located in Santa Fe Springs, California. Applied BioCode develops, manufactures, and markets high...

Applied Molecular

Applied Molecular Evolution, Inc. (AME) is a leader in the application of directed molecular evolution to improve healthcare by optimizing and developing human biotherapeutics. AME uses its proprietar...

Applied Biosystems (Australia)

Applied Biosystems has demonstrated its position as a technology leader and driving force in the changing dynamics of the life science marketplace. The Applied Biosystems business is focused on the fo...

Applied Precision, Inc.

Applied Precision is a leading provider of innovative microscopy imaging, measurement and analysis systems for the life sciences industries and OEM markets. Headquartered in Issaquah, Washington, just...

Molecular Templates Inc.

Molecular Templates Inc. is creating an entirely new generation of potent anti-cancer agents based on proprietary applied proteomics technologies.The novel therapeutic agents in development by MTI are...

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