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Biocept Incorporated Company Profile

06:26 EDT 21st September 2017 | BioPortfolio

Privately held Biocept was founded in 1997 and is based in Carlsbad, California near San Diego.

Biocept is emerging as a leader in the development and commercialization, in part through partners, of Next Generation Microarrays for Genomics and Proteomics™. Biocept’s proprietary platform technology is based on novel hydrogel polymers. The resulting three-dimensional microarrays have very high sensitivity, excellent precision and a broad dynamic range. Biocept has already developed several assay formats for the analysis of samples containing nucleic acids or proteins. Biocept has collaborations with investigators at leading research organizations for prototype microarrays to monitor the expression of apoptosis-related genes.



Life Sciences applications of Biocept’s genomic and proteomic microarrays include pharmaceutical research and development [e.g. target identification and validation, expression profiling, pathway analysis, high throughput screening, ADMET studies, and detection of single nucleotide polymorphisms (SNP's)] and clinical diagnostics.



Science & Technology:



Successful genomic and proteomic research requires tools that can rapidly and accurately provide results. While gene expression profiling is frequently the first step, protein expression may ultimately be more important, since proteins are the targets for most drugs. Gene expression does not always correlate well with the amount or activity of expressed proteins. In addition, protein diversity and activity results from alternative splicing at the messenger RNA level and by post-translational modifications such as phosphorylation and glycosylation. Several forms of a single protein may have important roles either as targets for drug discovery or as indicators of toxicity. These relationships demonstrate the crucial importance of proteomics in drug discovery.



Biocept's platform technology uses proprietary hydrogel polymers to create three-dimensional microarrays. Biocept prints microdroplets in an array on a treated glass slide. Each microdroplet contains a large number of molecules of a single probe, uniformly dispersed within and covalently bound to the hydrogel matrix. Key features of Biocept's microarrays are:



§ Versatile-useful for genomic and proteomic applications-



Biocept has developed and demonstrated the utility of genomic and proteomic microarrays in formats suitable for many life sciences applications.



§ High probe density provides high precision and broad dynamic range-



The higher probe density provides a lower coefficient of variation and broader dynamic range than conventional two-dimensional microarrays.



· Aqueous environment allows biomolecular probes to retain native conformation and activity-



Probes tethered within a hydrogel microdroplet retain their native three-dimensional configuration and activity, improving interaction with targets in the sample.



§ Readily manufactured-



Microdroplets about 300 microns in diameter and 30 microns thick are deposited as an array on a treated glass slide.



Biocept’s platform technology is protected by issued or pending patents in all major pharmaceutical markets.



Commercialization Strategy:



Biocept is establishing corporate partnerships and other collaborations to accelerate the development, commercialization and utilization of microarrays based on its technology. This includes partnerships with Pharmaceutical/Biotech companies for research and development, collaborations with Life Science Reagents companies, partnerships for clinical diagnostics, and partnerships to enhance technology development and commercialization.

Location

2151 Las Palmas Drive, Suite C
Carlsbad
CA
92009
United States of America

Contact

Phone: (760) 804-9580 x15
Fax: (760) 804-6238
Email: kbrown@biocept


News Articles [35 Associated News Articles listed on BioPortfolio]

Biocept Raises $2.2 Million from Ally Bridge; Plans China Expansion

Biocept , a San Diego liquid biopsy company, raised $2.2 million from Hong Kong's Ally Bridge LB Healthcare Master Fund in a private placement. Biocept provides physicians with personal medicine tests...

Biocept, UT Southwestern to study liquid biopsy platform in ALK-positive non-small cell lung cancer

Biocept Inc. and University of Texas Southwestern Medical Center entered a clinical study agreement to evaluate the clinical utility of Biocept’s Target Selector platform for patients with ALK-posit...

Biocept launches new liquid biopsy test for progesterone receptor detection

Biocept has announced the commercial availability of its new liquid biopsy test for progesterone receptor (PR), which can be used for the detection and monitoring of a key biomarker in the blood of pa...

Biocept and UT Southwestern Medical Center Announce Study to Profile & Monitor NSCLC Cancer Patients with ALK Rearrangements

SAN DIEGO, Aug. 17, 2017 /PRNewswire/ — Biocept, Inc. (NASDAQ: BIOC), a leading commercial provider of liquid biopsy tests designed to provide physicians with clinically actionable information t...

Biocept to Release Second Quarter 2017 Financial Results and Host Investor Conference Call on August 10, 2017

SAN DIEGO, Aug. 3, 2017 /PRNewswire/ -- Biocept, Inc. (NASDAQ: BIOC), a leading commercial provider of liquid biopsy tests designed to provide physicians with clinically actionable information to...

Biocept to Present at the 6th Annual Gateway Conference on September 6, 2017 in San Francisco

SAN DIEGO, Aug. 28, 2017 /PRNewswire/ -- Biocept, Inc. (NASDAQ: BIOC), a leading commercial provider of liquid biopsy tests designed to provide physicians with clinically actionable information t...

Biocept completes $2.2M private placement with Ally Bridge

Biocept (BIOC) Presents At 6th Annual Liolios Gateway Conference - Slideshow

PubMed Articles [1 Associated PubMed Articles listed on BioPortfolio]

AERODYNAMIC PROPERTIES AND IN SILICO DEPOSITION OF MELOXICAM POTASSIUM INCORPORATED IN A CARRIER-FREE DPI PULMONARY SYSTEM.

Dry powder inhalers (DPIs) have been among the fastest developing inhaler forms in the past decades. Researches are focusing on the formulation of carrier-free powders to obtain a higher deep-lung dep...

Clinical Trials [0 Results]

None

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